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The map label for this gene is potH [H]

Identifier: 126447357

GI number: 126447357

Start: 432407

End: 433666

Strand: Direct

Name: potH [H]

Synonym: BMA10247_A0484

Alternate gene names: 126447357

Gene position: 432407-433666 (Clockwise)

Preceding gene: 126447505

Following gene: 126447774

Centisome position: 18.38

GC content: 67.46

Gene sequence:

>1260_bases
ATGACGATCGCTACGCAGTCGGCGCCGCCGACTCAATCGCTCAGGCGTGAACTGAAAGCGGCCGAGGCCAGGCGGCGCAC
GATGGCGCTGCTGCTCGTCGCGCCGCTCGCGATATTCCTGCTGCTCGTGTTCGTCGTGCCGATCGGCGCGTTGCTCACGC
GCGCGGTGCAGAATCCCGAGATCGCGACCGCGCTGCCGCGCACCGTGGCCGCGCTGTCGAACTGGGACCGCAAGGCGGCG
CCCGCCGACGCGGCGTACGCGGCGCTCGCCGCCGATCTCACGCAGATCGCCGACGGCGAGGCGATGGGCGCGCTCGCGCG
ACGCCTGAACACCGAGATACCCGGCTATCGGTCGCTCGTCGCGAAGACCGCGCGCGCGATGCCGCTGACGGGCGACGCGA
ACGCGCCGCTCGCGCCGGCGCAGACGCGTGCGAAGCTGATCGAGCTCGACGAGCGCTGGGGCGACGCCGCGTACTGGCAG
GCGATCGCGAAGAACGGCGGCCGCTATTCGCCGTTCTACCTGCTCGCGGCGCTCGATCACAAGCAGGACGGTTTCGGCAG
CATCGTGCCCGCCGATCCCGATCAATCGATCTACCTCGCGGTGTTCGGCCGCACGCTGCTGATCGGCTTCGCGGTCACGC
TGTTCGCGCTCGCGCTCGGCTATCCGCTCGCGTACTGGATCTCGACGCTGCCCGAGCGGCGCGCGAATCTCGCGATGATC
CTCGTGCTGATTCCGTTCTGGACGTCGGTGCTCGTGCGCGTCGCCGCCTGGATCGTGCTGCTGCAAAGCGAAGGGCTCGT
CAATCGCGCGCTGATCGACACCGGACTGATTTCGCAGCCGCTCGCGCTGTTGTTCAATCGCGTCGGCGTCTACATCTCGA
TGACGCACATCCTGCTGCCGTTCATGATCCTGCCGCTCTACAGCGTGATGAAATCGATTCCGCCGAGCTATCAGCGCGCG
GCGGTGTCGCTCGGCAGCCATCCGTTCGCGGCGTTCTGGCGCGTGTACGTGCCGCAGACCTATCCGGGCGTCGGCGCGGG
CGCGCTGCTCGTCTTCATTCTCGCGATCGGCTACTACATCACGCCCGCGTTGCTCGGCGGTCCGAACGATCAGATGGTCA
GCTACTACGTTGCGTACTTCACGAACGTGACGATCAACTGGGGCATGGCGTGTGCGCTCGGCGGCCTGCTGCTCGCCGCG
ACGCTCGTGCTGTATGCGATCTACGGCCGCTTTACGCGCTCGCAATTGAGCCTCGGCTGA

Upstream 100 bases:

>100_bases
CGGCCGCGTGAGCCGGTGAAGCAAACGGCCGCGCGCGCCGTGGCGGCGTGCGCGACGTTCCTCCGAACGGCGTTTCGGCC
GGAGACAACCGTTGAATACG

Downstream 100 bases:

>100_bases
ATGAGCGCCGAGCGAACAGGGGAAACGAACATGAAACTGCTGGCGAAGCCGCTCTTCGCGCCGCACATGTCGGGGCTCGA
GCGCGCCTGGTATTTCGCGC

Product: spermidine/putrescine ABC transporter, permease protein

Products: ADP; phosphate; putrescine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MTIATQSAPPTQSLRRELKAAEARRRTMALLLVAPLAIFLLLVFVVPIGALLTRAVQNPEIATALPRTVAALSNWDRKAA
PADAAYAALAADLTQIADGEAMGALARRLNTEIPGYRSLVAKTARAMPLTGDANAPLAPAQTRAKLIELDERWGDAAYWQ
AIAKNGGRYSPFYLLAALDHKQDGFGSIVPADPDQSIYLAVFGRTLLIGFAVTLFALALGYPLAYWISTLPERRANLAMI
LVLIPFWTSVLVRVAAWIVLLQSEGLVNRALIDTGLISQPLALLFNRVGVYISMTHILLPFMILPLYSVMKSIPPSYQRA
AVSLGSHPFAAFWRVYVPQTYPGVGAGALLVFILAIGYYITPALLGGPNDQMVSYYVAYFTNVTINWGMACALGGLLLAA
TLVLYAIYGRFTRSQLSLG

Sequences:

>Translated_419_residues
MTIATQSAPPTQSLRRELKAAEARRRTMALLLVAPLAIFLLLVFVVPIGALLTRAVQNPEIATALPRTVAALSNWDRKAA
PADAAYAALAADLTQIADGEAMGALARRLNTEIPGYRSLVAKTARAMPLTGDANAPLAPAQTRAKLIELDERWGDAAYWQ
AIAKNGGRYSPFYLLAALDHKQDGFGSIVPADPDQSIYLAVFGRTLLIGFAVTLFALALGYPLAYWISTLPERRANLAMI
LVLIPFWTSVLVRVAAWIVLLQSEGLVNRALIDTGLISQPLALLFNRVGVYISMTHILLPFMILPLYSVMKSIPPSYQRA
AVSLGSHPFAAFWRVYVPQTYPGVGAGALLVFILAIGYYITPALLGGPNDQMVSYYVAYFTNVTINWGMACALGGLLLAA
TLVLYAIYGRFTRSQLSLG
>Mature_418_residues
TIATQSAPPTQSLRRELKAAEARRRTMALLLVAPLAIFLLLVFVVPIGALLTRAVQNPEIATALPRTVAALSNWDRKAAP
ADAAYAALAADLTQIADGEAMGALARRLNTEIPGYRSLVAKTARAMPLTGDANAPLAPAQTRAKLIELDERWGDAAYWQA
IAKNGGRYSPFYLLAALDHKQDGFGSIVPADPDQSIYLAVFGRTLLIGFAVTLFALALGYPLAYWISTLPERRANLAMIL
VLIPFWTSVLVRVAAWIVLLQSEGLVNRALIDTGLISQPLALLFNRVGVYISMTHILLPFMILPLYSVMKSIPPSYQRAA
VSLGSHPFAAFWRVYVPQTYPGVGAGALLVFILAIGYYITPALLGGPNDQMVSYYVAYFTNVTINWGMACALGGLLLAAT
LVLYAIYGRFTRSQLSLG

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine [H]

COG id: COG1176

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component I

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787080, Length=228, Percent_Identity=35.0877192982456, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1787369, Length=223, Percent_Identity=31.8385650224215, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787713, Length=180, Percent_Identity=31.6666666666667, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 45312; Mature: 45181

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIATQSAPPTQSLRRELKAAEARRRTMALLLVAPLAIFLLLVFVVPIGALLTRAVQNPE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
IATALPRTVAALSNWDRKAAPADAAYAALAADLTQIADGEAMGALARRLNTEIPGYRSLV
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHH
AKTARAMPLTGDANAPLAPAQTRAKLIELDERWGDAAYWQAIAKNGGRYSPFYLLAALDH
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCEEEEEECCC
KQDGFGSIVPADPDQSIYLAVFGRTLLIGFAVTLFALALGYPLAYWISTLPERRANLAMI
CCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVLIPFWTSVLVRVAAWIVLLQSEGLVNRALIDTGLISQPLALLFNRVGVYISMTHILLP
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMILPLYSVMKSIPPSYQRAAVSLGSHPFAAFWRVYVPQTYPGVGAGALLVFILAIGYYI
HHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
TPALLGGPNDQMVSYYVAYFTNVTINWGMACALGGLLLAATLVLYAIYGRFTRSQLSLG
HHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIATQSAPPTQSLRRELKAAEARRRTMALLLVAPLAIFLLLVFVVPIGALLTRAVQNPE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
IATALPRTVAALSNWDRKAAPADAAYAALAADLTQIADGEAMGALARRLNTEIPGYRSLV
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHH
AKTARAMPLTGDANAPLAPAQTRAKLIELDERWGDAAYWQAIAKNGGRYSPFYLLAALDH
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCEEEEEECCC
KQDGFGSIVPADPDQSIYLAVFGRTLLIGFAVTLFALALGYPLAYWISTLPERRANLAMI
CCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVLIPFWTSVLVRVAAWIVLLQSEGLVNRALIDTGLISQPLALLFNRVGVYISMTHILLP
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMILPLYSVMKSIPPSYQRAAVSLGSHPFAAFWRVYVPQTYPGVGAGALLVFILAIGYYI
HHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
TPALLGGPNDQMVSYYVAYFTNVTINWGMACALGGLLLAATLVLYAIYGRFTRSQLSLG
HHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; putrescine [Periplasm]; H2O [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8416922; 8905232; 9278503 [H]