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The map label for this gene is frlR [H]

Identifier: 126446969

GI number: 126446969

Start: 448997

End: 449797

Strand: Direct

Name: frlR [H]

Synonym: BMA10247_A0498

Alternate gene names: 126446969

Gene position: 448997-449797 (Clockwise)

Preceding gene: 126447152

Following gene: 126446434

Centisome position: 19.08

GC content: 67.92

Gene sequence:

>801_bases
ATGACTTCCAATCAGGCGAGCGCACCCAATCCGAACGGCCAGGCCGGCTCCACGCAGCCGGGCGGCGAGGCCGCGGCTGC
GCCATCGCCCACTTTCAGCCCGCTCTACCGGCAGATCAAGGCGCTCATCACGCAGAGCCTCGAGGCGGGCGAGTGGAAGC
CGGGCGAGATCATCCCGAGCGAAGTCGAACTCGCCGGCCGCTATAAGGTGAGCCAGGGCACGGTGCGCAAGGCCATCGAC
GAGCTGGCGGCCGACAACCTGCTCGTGCGCCGCCAGGGCAAGGGCACGTTCGTCGCGACCCACAGCGAGGAGCGTGCGCA
ATTCCGGTTCCTGCGGCTGCTCGCCGACGACGGCGCCGAGCATCCGCACGTGAGCCGGCTGCTCGAATGCCGGCGGATGC
GCGCGCCCGCCGAGATCGCGCGCCAGCTCGATCTGAAACCGGCCGACCCCGTCGTCCAGGTGCGGCGCGTGCTCGAGTTC
GACGGCGTCGATACGGTGCTCGACGAGATCTGGCTGCCGGGCGCGATGTTCCGGGGGCTCACGTTCGAGCGTCTGAGCGA
ATACAAGGGGCCGCTCTACGCGATGTTCGAGAGCGAGTTCGGCACGCGGATGATCCGCGCAAGCGAGAAGATTCGTGCGA
TCGCGGCCGAGCCCGCCGTCGCCGACGTGCTGCGGGTGCCGCCCGGTTTTCCGCTGCTGTCGGTCGAGCGCGTGTCGTAC
ACGTATGGCGATCGTCCCGTCGAAGTGCGGCGCGGATGGTATGTCACAACCGGGTACTACTATCAGAACGATTTGAGCTG
A

Upstream 100 bases:

>100_bases
GACGGGTAAAGTCAAACGGTATCTTATGTCTTATATAAGACAGATGTTTTCGAGGGAAAAATCTGGACGGAAAAGCGCGA
TTCATGATGAAATGCGCGCC

Downstream 100 bases:

>100_bases
AATTCGGATTCAAGGTAAGGCGTAGCCTGAACCAAGGTCAGGCGAAACGACGGGTAATTGCGCTTCCCACGCGCATAGCA
CGTTTCGCGACGCGTTTATA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MTSNQASAPNPNGQAGSTQPGGEAAAAPSPTFSPLYRQIKALITQSLEAGEWKPGEIIPSEVELAGRYKVSQGTVRKAID
ELAADNLLVRRQGKGTFVATHSEERAQFRFLRLLADDGAEHPHVSRLLECRRMRAPAEIARQLDLKPADPVVQVRRVLEF
DGVDTVLDEIWLPGAMFRGLTFERLSEYKGPLYAMFESEFGTRMIRASEKIRAIAAEPAVADVLRVPPGFPLLSVERVSY
TYGDRPVEVRRGWYVTTGYYYQNDLS

Sequences:

>Translated_266_residues
MTSNQASAPNPNGQAGSTQPGGEAAAAPSPTFSPLYRQIKALITQSLEAGEWKPGEIIPSEVELAGRYKVSQGTVRKAID
ELAADNLLVRRQGKGTFVATHSEERAQFRFLRLLADDGAEHPHVSRLLECRRMRAPAEIARQLDLKPADPVVQVRRVLEF
DGVDTVLDEIWLPGAMFRGLTFERLSEYKGPLYAMFESEFGTRMIRASEKIRAIAAEPAVADVLRVPPGFPLLSVERVSY
TYGDRPVEVRRGWYVTTGYYYQNDLS
>Mature_265_residues
TSNQASAPNPNGQAGSTQPGGEAAAAPSPTFSPLYRQIKALITQSLEAGEWKPGEIIPSEVELAGRYKVSQGTVRKAIDE
LAADNLLVRRQGKGTFVATHSEERAQFRFLRLLADDGAEHPHVSRLLECRRMRAPAEIARQLDLKPADPVVQVRRVLEFD
GVDTVLDEIWLPGAMFRGLTFERLSEYKGPLYAMFESEFGTRMIRASEKIRAIAAEPAVADVLRVPPGFPLLSVERVSYT
YGDRPVEVRRGWYVTTGYYYQNDLS

Specific function: May regulate the transcription of the frlABCD operon [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082252, Length=217, Percent_Identity=29.4930875576037, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786950, Length=235, Percent_Identity=30.2127659574468, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790540, Length=222, Percent_Identity=28.3783783783784, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790118, Length=210, Percent_Identity=28.0952380952381, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 29568; Mature: 29437

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSNQASAPNPNGQAGSTQPGGEAAAAPSPTFSPLYRQIKALITQSLEAGEWKPGEIIPS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
EVELAGRYKVSQGTVRKAIDELAADNLLVRRQGKGTFVATHSEERAQFRFLRLLADDGAE
HHHHCCCEECCCCHHHHHHHHHHHCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHCCCC
HPHVSRLLECRRMRAPAEIARQLDLKPADPVVQVRRVLEFDGVDTVLDEIWLPGAMFRGL
CHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCHHHHHCC
TFERLSEYKGPLYAMFESEFGTRMIRASEKIRAIAAEPAVADVLRVPPGFPLLSVERVSY
CHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEHEEH
TYGDRPVEVRRGWYVTTGYYYQNDLS
CCCCCCEEEECCEEEEECEEECCCCC
>Mature Secondary Structure 
TSNQASAPNPNGQAGSTQPGGEAAAAPSPTFSPLYRQIKALITQSLEAGEWKPGEIIPS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
EVELAGRYKVSQGTVRKAIDELAADNLLVRRQGKGTFVATHSEERAQFRFLRLLADDGAE
HHHHCCCEECCCCHHHHHHHHHHHCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHCCCC
HPHVSRLLECRRMRAPAEIARQLDLKPADPVVQVRRVLEFDGVDTVLDEIWLPGAMFRGL
CHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCHHHHHCC
TFERLSEYKGPLYAMFESEFGTRMIRASEKIRAIAAEPAVADVLRVPPGFPLLSVERVSY
CHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEHEEH
TYGDRPVEVRRGWYVTTGYYYQNDLS
CCCCCCEEEECCEEEEECEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]