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The map label for this gene is ptxR [H]

Identifier: 126446665

GI number: 126446665

Start: 549728

End: 550666

Strand: Direct

Name: ptxR [H]

Synonym: BMA10247_A0604

Alternate gene names: 126446665

Gene position: 549728-550666 (Clockwise)

Preceding gene: 126445836

Following gene: 126445813

Centisome position: 23.37

GC content: 68.16

Gene sequence:

>939_bases
TTGACAATCGAGGGCGCGATGGTGAGTTTGGATCGTTTCGACGTGTTTCGCGCGGTCGTGGAGGCCGGCTCGTTTACGGG
CGCGGCGAACGTGCTGAACCAGGCGCGCGCGGCGGTGAGCTTCCACGTCAAGCAGCTCGAGGCCGAGCTCGGCGTGACGC
TGCTCACGCGGACGACGCGGCGCGTCGAGCTGACCGAAGCGGGCGAGCGCTTCTACGAGCGTTGCCTGCGTGTGCTTGCC
GAAGCCGAAGAGGCGATCGACGATGCGCGCGCCGAGCACGGCGGCATGCAGGGCAGCTTGCGCGTGACGTCGACGGTCGA
ATACGCGCTGCGGATCGTCGCGCCCGCCTTGAGCGAATTCATGAGCGCGCATCCGGCGTTGCGCGTGCGGCTCGAGACGC
ATACGTCGCAGGCGGATCTCGTGCGCGATCGCTTCGACGTTGCGATCCGGCTCGGTCGCCTTGAGCAGTTTCGGGATCTG
CCGTACCGGGGCGTATGTATCGACACGTACGACGTGCGGCCGGTGGCGTCGCCCGCACTGCTGGCCGCGCACGGTGTTGC
GCGAATCGACTCGCCGGAGGCGCTCGCGCGCCTGCCGCAGCTCGGGCACAGTCGGCTGTCGCAGGTCGCGTCGTGGCTGC
TGCACGATCGCGACGGGCGCGAACACGTGTATCGGCCCGCGGCGAAGCCGCATCTGATCGCGGACAACGCGTCGGTGCTG
CGCGCGTTCGCGCAGCAGGGCGGTGGCGTCGCGCTGCTGCCCGAGTGGCTCGTGCGCGATGATTTGGCCAGCGGAACGTT
GATCGACGCGCTACCGGGTTACCGGTTTGCGCAACAGGGCGTCTACGCATTGTATCCGTCGGCGCGGCACGTGCCGCAGA
AGATTCGCGCCTGGATCGATTTCATCAAGCGCTACGTTCGGCGGCGCGCGGAGGGTTGA

Upstream 100 bases:

>100_bases
GAGCGGACATGGCGGCCAACGGTGACATCGGGTGACGTAGTGTAAAGTCCGCGATCCGGGGCCGTCAGCCCGATTGCCCG
GATAGACTGATCGAAAAATT

Downstream 100 bases:

>100_bases
CGCTCGGCGCGCCGCCGGCGGGAGGCGGTGCGCAGGCCGGCACGAGCCGGCGCGATCGGGCACACGGCTTCCCGCGTACC
CGAACCGATCCCGCTTCACG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MTIEGAMVSLDRFDVFRAVVEAGSFTGAANVLNQARAAVSFHVKQLEAELGVTLLTRTTRRVELTEAGERFYERCLRVLA
EAEEAIDDARAEHGGMQGSLRVTSTVEYALRIVAPALSEFMSAHPALRVRLETHTSQADLVRDRFDVAIRLGRLEQFRDL
PYRGVCIDTYDVRPVASPALLAAHGVARIDSPEALARLPQLGHSRLSQVASWLLHDRDGREHVYRPAAKPHLIADNASVL
RAFAQQGGGVALLPEWLVRDDLASGTLIDALPGYRFAQQGVYALYPSARHVPQKIRAWIDFIKRYVRRRAEG

Sequences:

>Translated_312_residues
MTIEGAMVSLDRFDVFRAVVEAGSFTGAANVLNQARAAVSFHVKQLEAELGVTLLTRTTRRVELTEAGERFYERCLRVLA
EAEEAIDDARAEHGGMQGSLRVTSTVEYALRIVAPALSEFMSAHPALRVRLETHTSQADLVRDRFDVAIRLGRLEQFRDL
PYRGVCIDTYDVRPVASPALLAAHGVARIDSPEALARLPQLGHSRLSQVASWLLHDRDGREHVYRPAAKPHLIADNASVL
RAFAQQGGGVALLPEWLVRDDLASGTLIDALPGYRFAQQGVYALYPSARHVPQKIRAWIDFIKRYVRRRAEG
>Mature_311_residues
TIEGAMVSLDRFDVFRAVVEAGSFTGAANVLNQARAAVSFHVKQLEAELGVTLLTRTTRRVELTEAGERFYERCLRVLAE
AEEAIDDARAEHGGMQGSLRVTSTVEYALRIVAPALSEFMSAHPALRVRLETHTSQADLVRDRFDVAIRLGRLEQFRDLP
YRGVCIDTYDVRPVASPALLAAHGVARIDSPEALARLPQLGHSRLSQVASWLLHDRDGREHVYRPAAKPHLIADNASVLR
AFAQQGGGVALLPEWLVRDDLASGTLIDALPGYRFAQQGVYALYPSARHVPQKIRAWIDFIKRYVRRRAEG

Specific function: Transcriptional activator of the toxA (exotoxin) and regA genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=30.976430976431, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789440, Length=308, Percent_Identity=28.8961038961039, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789639, Length=315, Percent_Identity=30.1587301587302, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI87081978, Length=303, Percent_Identity=30.6930693069307, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI145693193, Length=306, Percent_Identity=28.7581699346405, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787589, Length=297, Percent_Identity=31.6498316498317, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1789173, Length=299, Percent_Identity=29.0969899665552, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787128, Length=317, Percent_Identity=26.1829652996845, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786448, Length=289, Percent_Identity=26.643598615917, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI157672245, Length=143, Percent_Identity=33.5664335664336, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788481, Length=305, Percent_Identity=24.9180327868852, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788706, Length=316, Percent_Identity=25.9493670886076, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787601, Length=124, Percent_Identity=29.8387096774194, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI145693105, Length=151, Percent_Identity=28.476821192053, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787806, Length=280, Percent_Identity=27.1428571428571, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34656; Mature: 34525

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIEGAMVSLDRFDVFRAVVEAGSFTGAANVLNQARAAVSFHVKQLEAELGVTLLTRTTR
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCH
RVELTEAGERFYERCLRVLAEAEEAIDDARAEHGGMQGSLRVTSTVEYALRIVAPALSEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHH
MSAHPALRVRLETHTSQADLVRDRFDVAIRLGRLEQFRDLPYRGVCIDTYDVRPVASPAL
HCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHH
LAAHGVARIDSPEALARLPQLGHSRLSQVASWLLHDRDGREHVYRPAAKPHLIADNASVL
HHHHCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEECCHHHH
RAFAQQGGGVALLPEWLVRDDLASGTLIDALPGYRFAQQGVYALYPSARHVPQKIRAWID
HHHHHCCCCEEECHHHHHHHHCCCCCHHHCCCCCHHHHCCEEEECCCHHHHHHHHHHHHH
FIKRYVRRRAEG
HHHHHHHHHCCC
>Mature Secondary Structure 
TIEGAMVSLDRFDVFRAVVEAGSFTGAANVLNQARAAVSFHVKQLEAELGVTLLTRTTR
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCH
RVELTEAGERFYERCLRVLAEAEEAIDDARAEHGGMQGSLRVTSTVEYALRIVAPALSEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHH
MSAHPALRVRLETHTSQADLVRDRFDVAIRLGRLEQFRDLPYRGVCIDTYDVRPVASPAL
HCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHH
LAAHGVARIDSPEALARLPQLGHSRLSQVASWLLHDRDGREHVYRPAAKPHLIADNASVL
HHHHCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEECCHHHH
RAFAQQGGGVALLPEWLVRDDLASGTLIDALPGYRFAQQGVYALYPSARHVPQKIRAWID
HHHHHCCCCEEECHHHHHHHHCCCCCHHHCCCCCHHHHCCEEEECCCHHHHHHHHHHHHH
FIKRYVRRRAEG
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8843437; 10984043 [H]