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The map label for this gene is yrkH [H]

Identifier: 126446396

GI number: 126446396

Start: 371707

End: 372447

Strand: Reverse

Name: yrkH [H]

Synonym: BMA10247_A0424

Alternate gene names: 126446396

Gene position: 372447-371707 (Counterclockwise)

Preceding gene: 126447274

Following gene: 126446939

Centisome position: 15.83

GC content: 67.07

Gene sequence:

>741_bases
GTGATCCTACGGCAATTCCTCCATTGCGACCCGGTCGGCATTTCGTACCTCCTTGGATGCGGCGGCAAATCGACGGGTGT
CGTGGTCGATGCGGTGGCCGAGCCCGGCACCTACCTGCAAGCCGCCGCGGACGCCGGGATGAAGATCGATTACGTGATCG
ACACCCACGTGCACGCAGACCACCTGTCCACCGGCCCGGCGCTGGCCGACGCGGCCGGCGCCGCCTACGTGCTGTCCACG
AAGGCCGATGTCGTACTGCCGTTCAAGGGTGTCGAGGACGGTGACGAAATCCGGGTCGGCAACGTCGTCATCAAAGTGCT
CGAAACGCCCGGCCACACGCCGGAACACATCAGCCTGCTGGTGACGGACCGCACGCGCGCCGAGGAACCGTGGCTCGCGC
TGACCGGACATACGCTGATGATCGGCGACCTCGGCCGCACGGAGCTGGCGGAAAGCGCCGAAGCCGGCGCGCGGAATCTG
TTCCGCAGCGTGCGGACGCTCAAGTCGCTCCCCGATTATCTTCCGCTCCTTCCCGGCGCATTCGCGGGCTCGGCGTGCGG
ACGCGGCCTCAGCGCGACTCCGCTGTCGACGATCGGCTTCGAAAAGCGCCACAACGCGGCATTCGGCATCGACGACGAAG
CGGCATTCGTGCGGTTCATGCTGAGCGACATGCCGCCTGCGCCGCCTGAGGCGGCACGCCTGCGCGCAGCCAACTCCGGA
CGCAACCCTGACGAGATCTGA

Upstream 100 bases:

>100_bases
TCTCTTGCTTGGGTCCCGCACTTGACACTTGCGCCTCCCTGGTCAATCATTCTCGAAAATGATTGAATGTTACCACCCGT
ACGTACCAGGAGCAACTCAA

Downstream 100 bases:

>100_bases
TTCCATGAGCAAATCCACCATGCCGGCCGGCGGCGCCGCGATCCGGCTTGGTCTCAAGGAAAACTGGCGCCAGTTCGCAC
TACTCGTGCTGATCAATGCG

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MILRQFLHCDPVGISYLLGCGGKSTGVVVDAVAEPGTYLQAAADAGMKIDYVIDTHVHADHLSTGPALADAAGAAYVLST
KADVVLPFKGVEDGDEIRVGNVVIKVLETPGHTPEHISLLVTDRTRAEEPWLALTGHTLMIGDLGRTELAESAEAGARNL
FRSVRTLKSLPDYLPLLPGAFAGSACGRGLSATPLSTIGFEKRHNAAFGIDDEAAFVRFMLSDMPPAPPEAARLRAANSG
RNPDEI

Sequences:

>Translated_246_residues
MILRQFLHCDPVGISYLLGCGGKSTGVVVDAVAEPGTYLQAAADAGMKIDYVIDTHVHADHLSTGPALADAAGAAYVLST
KADVVLPFKGVEDGDEIRVGNVVIKVLETPGHTPEHISLLVTDRTRAEEPWLALTGHTLMIGDLGRTELAESAEAGARNL
FRSVRTLKSLPDYLPLLPGAFAGSACGRGLSATPLSTIGFEKRHNAAFGIDDEAAFVRFMLSDMPPAPPEAARLRAANSG
RNPDEI
>Mature_246_residues
MILRQFLHCDPVGISYLLGCGGKSTGVVVDAVAEPGTYLQAAADAGMKIDYVIDTHVHADHLSTGPALADAAGAAYVLST
KADVVLPFKGVEDGDEIRVGNVVIKVLETPGHTPEHISLLVTDRTRAEEPWLALTGHTLMIGDLGRTELAESAEAGARNL
FRSVRTLKSLPDYLPLLPGAFAGSACGRGLSATPLSTIGFEKRHNAAFGIDDEAAFVRFMLSDMPPAPPEAARLRAANSG
RNPDEI

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=171, Percent_Identity=30.9941520467836, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1787158, Length=211, Percent_Identity=26.5402843601896, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538952, Length=190, Percent_Identity=31.0526315789474, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221330176, Length=236, Percent_Identity=28.8135593220339, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR001763 [H]

Pfam domain/function: PF00753 Lactamase_B; PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 25937; Mature: 25937

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILRQFLHCDPVGISYLLGCGGKSTGVVVDAVAEPGTYLQAAADAGMKIDYVIDTHVHAD
CCHHHHHCCCCCCHHHEEECCCCCCCEEEEECCCCCHHHHHHHCCCCEEEEEEECCEECC
HLSTGPALADAAGAAYVLSTKADVVLPFKGVEDGDEIRVGNVVIKVLETPGHTPEHISLL
CCCCCCCHHHHCCCEEEEECCCCEEEEECCCCCCCCEEECCEEEEEECCCCCCCCCEEEE
VTDRTRAEEPWLALTGHTLMIGDLGRTELAESAEAGARNLFRSVRTLKSLPDYLPLLPGA
EECCCCCCCCEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCC
FAGSACGRGLSATPLSTIGFEKRHNAAFGIDDEAAFVRFMLSDMPPAPPEAARLRAANSG
CCCHHHCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCC
RNPDEI
CCCCCC
>Mature Secondary Structure
MILRQFLHCDPVGISYLLGCGGKSTGVVVDAVAEPGTYLQAAADAGMKIDYVIDTHVHAD
CCHHHHHCCCCCCHHHEEECCCCCCCEEEEECCCCCHHHHHHHCCCCEEEEEEECCEECC
HLSTGPALADAAGAAYVLSTKADVVLPFKGVEDGDEIRVGNVVIKVLETPGHTPEHISLL
CCCCCCCHHHHCCCEEEEECCCCEEEEECCCCCCCCEEECCEEEEEECCCCCCCCCEEEE
VTDRTRAEEPWLALTGHTLMIGDLGRTELAESAEAGARNLFRSVRTLKSLPDYLPLLPGA
EECCCCCCCCEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCC
FAGSACGRGLSATPLSTIGFEKRHNAAFGIDDEAAFVRFMLSDMPPAPPEAARLRAANSG
CCCHHHCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCC
RNPDEI
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]