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The map label for this gene is catR [C]

Identifier: 126446195

GI number: 126446195

Start: 197393

End: 198280

Strand: Direct

Name: catR [C]

Synonym: BMA10247_A0232

Alternate gene names: 126446195

Gene position: 197393-198280 (Clockwise)

Preceding gene: 126446731

Following gene: 126447088

Centisome position: 8.39

GC content: 71.73

Gene sequence:

>888_bases
ATGGAACTGCGTCAGCTCCGGTATTTCATCGCGGTGGCCGAGGAGATGAACATCACGCGCGCCGCGCAGCGCCTGCACAT
GACGCAGCCGCCGCTCAGCCGCCAGCTTCAACTGATCGAGGACGAGATCGGCCTGCCGCTGTTCGAGCGCGGCGCGCGGC
CGCTGAAGCTGACCGACGCCGGGCGGGTGCTGTACGCGCAGGCGCGGCGCGTGCTCGAACAGGCCGACGAGCTCGCGCCG
CTCACGCGGCGGCTCGCGCAGGCGGCCGAGCGGATCGTGATCGGCTTCGTGCCGTCGACGCTGTACGGCGCGCTGCCCGA
GGTGATCCGCGCGTTTCGCGAGGCCGCGCCGGCCGTCGAGCTTTCGCTGATCGAAATGTTCACGCTCGAGCAGCTCGGCG
CGCTCAAGGGCGGGCGCATCGACATCGGCTTCGGCCGGCTGCGCTTCGACGACGATCGGCTCGTGCGCGAGGTGCTCGTC
GAAGAGCGGCTGATCGCGGCGCTGCCGGACGGGCATCCGCTCGCCGCGCCCGATGCGTCGATCTCGCTGGCGGACATCGC
CGGGCAGACGTTGATCGTCTACCCGAGCACGCCCCGGCCGAGCTTCGCCGACCAGCAACTGTCCGCGCTGCGCGACGGCG
GGCTCGCGCCCGTCGCGGTGCACGAGGTGCGCGAGCTGCAGACGGCGCTCGGGCTCGTCGCCGCGCAGGTCGGCGTATCG
CTTGTGCCGGAGAGCGTCGAGGGCGTGAGGGTGAAGGGTGTCGTCTACCGGCGGCTGCCGGAGCCCGTCGCGACCTCGCC
GATCATCCTGAGCCGGCGGCTGCACGACGAAAGCCGCGCGACCGCGCTGTTCTGCTCGCTCGCGCGCAAACTGATGGCGG
GCCACTGA

Upstream 100 bases:

>100_bases
GTTGCTATCATCGGAACCCTCCTGTCGCACACATGGTAGAAACAAACGCGCGACGGCGTCCAACACCCTTTCCGACTACT
TCCATACTTTCGAGGTATGC

Downstream 100 bases:

>100_bases
CGCGTGCCGCGCGCTCCGGCGGGCGTGAGGCGAAAGGAGAACGAAGGAATCAGGCGTCGCGCCGATCGGCGAGCGTCGCG
GACGGCAGCTCGCCGAACCG

Product: cat operon transcriptional activator CatR

Products: NA

Alternate protein names: ORFR1 [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MELRQLRYFIAVAEEMNITRAAQRLHMTQPPLSRQLQLIEDEIGLPLFERGARPLKLTDAGRVLYAQARRVLEQADELAP
LTRRLAQAAERIVIGFVPSTLYGALPEVIRAFREAAPAVELSLIEMFTLEQLGALKGGRIDIGFGRLRFDDDRLVREVLV
EERLIAALPDGHPLAAPDASISLADIAGQTLIVYPSTPRPSFADQQLSALRDGGLAPVAVHEVRELQTALGLVAAQVGVS
LVPESVEGVRVKGVVYRRLPEPVATSPIILSRRLHDESRATALFCSLARKLMAGH

Sequences:

>Translated_295_residues
MELRQLRYFIAVAEEMNITRAAQRLHMTQPPLSRQLQLIEDEIGLPLFERGARPLKLTDAGRVLYAQARRVLEQADELAP
LTRRLAQAAERIVIGFVPSTLYGALPEVIRAFREAAPAVELSLIEMFTLEQLGALKGGRIDIGFGRLRFDDDRLVREVLV
EERLIAALPDGHPLAAPDASISLADIAGQTLIVYPSTPRPSFADQQLSALRDGGLAPVAVHEVRELQTALGLVAAQVGVS
LVPESVEGVRVKGVVYRRLPEPVATSPIILSRRLHDESRATALFCSLARKLMAGH
>Mature_295_residues
MELRQLRYFIAVAEEMNITRAAQRLHMTQPPLSRQLQLIEDEIGLPLFERGARPLKLTDAGRVLYAQARRVLEQADELAP
LTRRLAQAAERIVIGFVPSTLYGALPEVIRAFREAAPAVELSLIEMFTLEQLGALKGGRIDIGFGRLRFDDDRLVREVLV
EERLIAALPDGHPLAAPDASISLADIAGQTLIVYPSTPRPSFADQQLSALRDGGLAPVAVHEVRELQTALGLVAAQVGVS
LVPESVEGVRVKGVVYRRLPEPVATSPIILSRRLHDESRATALFCSLARKLMAGH

Specific function: Probable positive regulator of the cat1 operon which encode enzymes responsible for the degradation of catechol to acetyl-CoA via the beta-ketoadipate pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=284, Percent_Identity=36.6197183098592, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1788887, Length=294, Percent_Identity=29.9319727891156, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI2367136, Length=264, Percent_Identity=30.3030303030303, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1790399, Length=244, Percent_Identity=29.5081967213115, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI145693105, Length=245, Percent_Identity=28.9795918367347, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI87081904, Length=185, Percent_Identity=32.972972972973, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI157672245, Length=285, Percent_Identity=27.719298245614, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787601, Length=294, Percent_Identity=26.8707482993197, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787530, Length=199, Percent_Identity=29.1457286432161, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788296, Length=202, Percent_Identity=32.6732673267327, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788297, Length=255, Percent_Identity=26.2745098039216, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790262, Length=263, Percent_Identity=29.6577946768061, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787806, Length=249, Percent_Identity=24.8995983935743, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789204, Length=299, Percent_Identity=28.4280936454849, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082132, Length=247, Percent_Identity=26.7206477732794, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788481, Length=176, Percent_Identity=30.6818181818182, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790208, Length=287, Percent_Identity=26.1324041811847, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1790783, Length=160, Percent_Identity=28.75, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32349; Mature: 32349

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRQLRYFIAVAEEMNITRAAQRLHMTQPPLSRQLQLIEDEIGLPLFERGARPLKLTDA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHCCCCCEEECCC
GRVLYAQARRVLEQADELAPLTRRLAQAAERIVIGFVPSTLYGALPEVIRAFREAAPAVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHCCCHH
LSLIEMFTLEQLGALKGGRIDIGFGRLRFDDDRLVREVLVEERLIAALPDGHPLAAPDAS
HHHHHHHHHHHHHCCCCCEEEEECCCEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
ISLADIAGQTLIVYPSTPRPSFADQQLSALRDGGLAPVAVHEVRELQTALGLVAAQVGVS
EEHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LVPESVEGVRVKGVVYRRLPEPVATSPIILSRRLHDESRATALFCSLARKLMAGH
HCCCCCCCEEEHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELRQLRYFIAVAEEMNITRAAQRLHMTQPPLSRQLQLIEDEIGLPLFERGARPLKLTDA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHCCCCCEEECCC
GRVLYAQARRVLEQADELAPLTRRLAQAAERIVIGFVPSTLYGALPEVIRAFREAAPAVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHCCCHH
LSLIEMFTLEQLGALKGGRIDIGFGRLRFDDDRLVREVLVEERLIAALPDGHPLAAPDAS
HHHHHHHHHHHHHCCCCCEEEEECCCEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
ISLADIAGQTLIVYPSTPRPSFADQQLSALRDGGLAPVAVHEVRELQTALGLVAAQVGVS
EEHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LVPESVEGVRVKGVVYRRLPEPVATSPIILSRRLHDESRATALFCSLARKLMAGH
HCCCCCCCEEEHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9473520 [H]