Click here to switch to the map view.

The map label for this gene is cckA [C]

Identifier: 126445955

GI number: 126445955

Start: 133852

End: 135687

Strand: Reverse

Name: cckA [C]

Synonym: BMA10247_A0163

Alternate gene names: 126445955

Gene position: 135687-133852 (Counterclockwise)

Preceding gene: 126447949

Following gene: 126447571

Centisome position: 5.77

GC content: 69.88

Gene sequence:

>1836_bases
ATGCACGTCGAGGTATTCGCACAACACCCAAGTTGTCCCGGCTGGCACGGCGAAATGGCCCGGCGCATCCGTGCGTTCGA
CTGGTCCGCCACCGAGCTCGGGCCGCTCGAGCGCTGGCCGGCCAGCCTCGTCGCCGCCGTGCGCACGGTGCTCGCGTCGC
CGGTCCCGCTCGTGATGCTGTGGGGCGCGTCCGGCTACATGCTCTACAACGACGCCTATGCGGCGTTCGCGGGCGGCCGT
CATCCGTATTTGCTCGGCCAGCCGGTCGAGCTCGGCTGGCCCGAAGTGGCCGATTTCAATCGCAACGTGATGCGCACGTG
CCTCGCGGGCGGCGCGCTGTCGTATCGCGACAAGGCGCTCGTGCTGCTGCGCAACGGCCGCCCGGAAGAAGTCTGGATGG
ATTTGTACTACAGCCCCCTCGCGGGCGACGACGGCGCGCCCGCCGGCGTGCTCGTGGTCGTCGTGGAGACCACCGAGCGG
GTGCTCGCCGCGCGGCATCGCGATCGTGCGAAGGCGGCGCTGCACGAAACCAACGCCGAGCTGCGCCGGCTCACCGAGAC
GCTCGAACAGCGGGTGGCGGACGCGATCACCGAGCGCGCGTCGATCGAGGAGCAATTGCGTCAGGCGCAAAAGATGGAAG
CGATCGGCAGCCTGACGGGCGGCATCGCGCACGATTTCAACAACGTGCTGCAAGTGGTCAGCAGCAATCTGCAAATGCTC
TCGGCCGAACTCGGCGAAGACGCCCGCGCACAGCGCCGCATCGCGAGCGCCGCCAACGCGGTGGCGCGCGGCGCGCAGCT
CGCGTCGCATCTGCTCGCGTTCGCGAGGCGCCAGCCGTTGGCGCCGGCGGTGCTCGACCCGCGCGGGCTCATCGACGGCA
TGAGGGAAATGCTGCATCGGGCGCTCGGCGAATCGGTCCATGTCGATGCCGATCTGCGCGACGACGTCTGGAACGTGCTC
GCGGATCGCCATCAGTTCGAGAACGCGCTGCTCAATCTCGCGATCAACGCGCGCGATGCGATGCGCGGCGAAGGCACGCT
GAAGATCACCGCGTGCAACATCGTGCTCGAAGCGGGCCGTCACGCGCGGCGCAACGGGTTGCCGCCCGGCGAGTACGTCG
CGTTCGACATCGCCGACAACGGCGTCGGCATGACGCCCGACATACTGGAGCGGGTGTTCGAGCCGTTTTTCACGACGAAG
CCGGACGGCCAGGGCACGGGCCTCGGGCTCAGCATGGTGTTCGGCTTCGTCAAGCAGAGCGGCGGCCACACGTCGATCGA
AAGCGCGCCGGGCCGCGGCACCACGGTGCGGCTGCTGCTTCCGCGCTGTCGCGAAGCGCCGGCCGGCGAGCCGGCCGCGC
AGCGGCGGCTTCCGGCCGAGGGCGGCCGCGAGACGATCCTCGTCGTCGAGGACGATGCGGACGTGCGGCTCGCCGTCGTC
GACATGCTCGCGCAGCTCGGCTACAAGGTGATCACCGCATCGGACGGCAAAGCGGGCCTTCTCGCGCTCGAAAGCGGAGC
GCCGATCGATTTGCTGTTTACCGACGTGATCATGCCCGGCCGCATCAAGGGCGGCGAACTGGCGCGGCGAGCGGCGCAGC
GCGTGCCGCCCGTGCCCGTGCTGTTCACGTCCGGCTACACGCGCGACGAGATCTTCCACGCGGGACGGCTCGATCCTGGC
GTGATGCTGCTCGGCAAGCCGTACCGGCGCGACGAGCTCGCACACAAGGTGCGCAGCGTGCTCGACGCACATGCGTCGGC
GCGGCGCGCTCACGGCGCGCGGCACGCGCAGGCGGACCCTCGCGCGAAAACGGCCGCCGCACGCGTGCAGCGGTAG

Upstream 100 bases:

>100_bases
CGCCTCGTCGCATCGCGCGCCGATCCTGTTCTAGAATGAGCGGGCGATCGCGCTGCGCAGCACGTGGAGCGCGCCGCCAC
GTTCGTCACGGAGCGCACGC

Downstream 100 bases:

>100_bases
CGCGAAGCGCGACGCTGGCGCTGGCGATGGCGATGGCGATGGCGATGGCGATGCTACCGGCGGCGAAACGCTCGTCCGGG
CGCTTCGCTTGCCGTGCGTG

Product: sensory box histidine kinase/response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 611; Mature: 611

Protein sequence:

>611_residues
MHVEVFAQHPSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVMLWGASGYMLYNDAYAAFAGGR
HPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKALVLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLVVVVETTER
VLAARHRDRAKAALHETNAELRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQML
SAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLDPRGLIDGMREMLHRALGESVHVDADLRDDVWNVL
ADRHQFENALLNLAINARDAMRGEGTLKITACNIVLEAGRHARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTK
PDGQGTGLGLSMVFGFVKQSGGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVV
DMLAQLGYKVITASDGKAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPVLFTSGYTRDEIFHAGRLDPG
VMLLGKPYRRDELAHKVRSVLDAHASARRAHGARHAQADPRAKTAAARVQR

Sequences:

>Translated_611_residues
MHVEVFAQHPSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVMLWGASGYMLYNDAYAAFAGGR
HPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKALVLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLVVVVETTER
VLAARHRDRAKAALHETNAELRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQML
SAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLDPRGLIDGMREMLHRALGESVHVDADLRDDVWNVL
ADRHQFENALLNLAINARDAMRGEGTLKITACNIVLEAGRHARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTK
PDGQGTGLGLSMVFGFVKQSGGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVV
DMLAQLGYKVITASDGKAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPVLFTSGYTRDEIFHAGRLDPG
VMLLGKPYRRDELAHKVRSVLDAHASARRAHGARHAQADPRAKTAAARVQR
>Mature_611_residues
MHVEVFAQHPSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVMLWGASGYMLYNDAYAAFAGGR
HPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKALVLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLVVVVETTER
VLAARHRDRAKAALHETNAELRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQML
SAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLDPRGLIDGMREMLHRALGESVHVDADLRDDVWNVL
ADRHQFENALLNLAINARDAMRGEGTLKITACNIVLEAGRHARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTK
PDGQGTGLGLSMVFGFVKQSGGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVV
DMLAQLGYKVITASDGKAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPVLFTSGYTRDEIFHAGRLDPG
VMLLGKPYRRDELAHKVRSVLDAHASARRAHGARHAQADPRAKTAAARVQR

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=258, Percent_Identity=28.6821705426357, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1788549, Length=248, Percent_Identity=26.2096774193548, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87081816, Length=396, Percent_Identity=23.4848484848485, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=31.1688311688312, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI48994928, Length=284, Percent_Identity=26.4084507042254, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66346; Mature: 66346

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00584 PFKB_KINASES_2 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVEVFAQHPSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVML
CCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEE
WGASGYMLYNDAYAAFAGGRHPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKAL
ECCCCEEEECCCHHHHCCCCCCEEECCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCCEE
VLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLVVVVETTERVLAARHRDRAKAALHETNAE
EEEECCCCHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
LRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
SAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLDPRGLIDGMREMLHR
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
ALGESVHVDADLRDDVWNVLADRHQFENALLNLAINARDAMRGEGTLKITACNIVLEAGR
HCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHEEECCHHHHCCCCEEEEEEEHHHHHCCC
HARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTKPDGQGTGLGLSMVFGFVKQS
HHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCC
GGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVV
CCCCCCCCCCCCCCEEEEECHHHCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCCHHHHH
DMLAQLGYKVITASDGKAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPV
HHHHHCCCEEEEECCCCCEEEEECCCCCEEEHHHHHCCCCCCCCHHHHHHHHHHCCCCCE
LFTSGYTRDEIFHAGRLDPGVMLLGKPYRRDELAHKVRSVLDAHASARRAHGARHAQADP
EECCCCCHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
RAKTAAARVQR
HHHHHHHHCCC
>Mature Secondary Structure
MHVEVFAQHPSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVML
CCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEE
WGASGYMLYNDAYAAFAGGRHPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKAL
ECCCCEEEECCCHHHHCCCCCCEEECCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCCEE
VLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLVVVVETTERVLAARHRDRAKAALHETNAE
EEEECCCCHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
LRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
SAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLDPRGLIDGMREMLHR
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
ALGESVHVDADLRDDVWNVLADRHQFENALLNLAINARDAMRGEGTLKITACNIVLEAGR
HCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHEEECCHHHHCCCCEEEEEEEHHHHHCCC
HARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTKPDGQGTGLGLSMVFGFVKQS
HHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCC
GGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVV
CCCCCCCCCCCCCCEEEEECHHHCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCCHHHHH
DMLAQLGYKVITASDGKAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPV
HHHHHCCCEEEEECCCCCEEEEECCCCCEEEHHHHHCCCCCCCCHHHHHHHHHHCCCCCE
LFTSGYTRDEIFHAGRLDPGVMLLGKPYRRDELAHKVRSVLDAHASARRAHGARHAQADP
EECCCCCHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
RAKTAAARVQR
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA