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The map label for this gene is lipA [H]

Identifier: 126445060

GI number: 126445060

Start: 2420038

End: 2421120

Strand: Reverse

Name: lipA [H]

Synonym: BURPS668_A2505

Alternate gene names: 126445060

Gene position: 2421120-2420038 (Counterclockwise)

Preceding gene: 126443902

Following gene: 126442460

Centisome position: 77.41

GC content: 66.94

Gene sequence:

>1083_bases
ATGCGATCCAGGGCAGTGGCGGCGGCAGTCGCGTTCGCGGTGAGCGCGGCGCCCGCCGCGGGCATCGGGACTTTCCTCTC
GCTTGCAGGCACGCAAGCCGCCGCTGCGGCGACGAGCGCCGTCGACAACTACGCGGCCACCCAATATCCGATCATCCTCG
TGCACGGTCTGACCGGCACCGACAAATACGCGAACGTTCTCGAATACTGGTACGGCATCCGGGAAGACTTGCAGGCGCAC
GGCGCGCAGGTCTATGTCGCGAACCTGTCCGGCTTCCAGAGCGACGACGGGCCGAACGGACGCGGCGAACAGCTGCTCGC
ATACGTGCAGCAGGTGCTCGCCGCGACGGGCGCATCGAAGGTGAATCTGATCGGCCACAGCCAGGGCGGGCTGACCTCGC
GCTACGTCGCGGCCGTCGCGCCGCAACTGGTCGCATCGGTGACGACGATCGGCACGCCGCATCGCGGTTCGGAGTTCGCG
GACTTCGTGCAAACCGTGCTCGCGTACGATCCGACCGGCTTGTCGTCGACGGTGATCGCCGCGTTCGTCAATGTGTTCGG
CATCCTGACGAGCAGCACCAACAACACGAACCAGGACGCGCTCGCCGCGCTGAAGACGCTGACGACTTCGCAGGCCGCGA
CGTACAACCAGAACTATCCGAGCGCGGGCCTCGGCGCGCCGGGCTCATGCCAGACAGGGGCGCAGACCGAGACCGTAGGC
GGCAACACGCATCTGCTGTATTCGTGGGGCGGCACGGCGATCCAGCCGACGCTGTCGATTCTCGGCGTGACGGGCGCGAC
CGACACGAGCACGATTCCCGTCGTCGATCCGGCGAACGTGCTCGATGCGTCGACGCTCGCGATGCTCGGCTCCGGCACCG
TGATGATCAATCGCGGCTCCGGTGCGAACGACGGCCTCGTGTCGCGCTGCAGCTCGCTGTACGGCCAGGTGCTCGGCACG
AGCTACAAGTGGAACCACCTCGACGAGATCAACCAGTTGCTCGGCGTGCGCGGCGCGTACGCGGAGGATCCGGTCGCGGT
GATCCGCACGCATGCGAACCGGTTGAAGACGCAGGGTGTGTGA

Upstream 100 bases:

>100_bases
ATGCCGCGTGTGCGGGCGACGCGAAACGTAGGCGTGCGAACAGAAGCAATATTCCCATCCGATACGATTCAAACAACAGG
AGACGTACATGGCCAGAACG

Downstream 100 bases:

>100_bases
TCGATGAAGGGAGAAGGCAGCGTTGCGCGGCGCGTCGCGCTTTACTGTGTGGCCGGCGCCGTCGCGGCCGGCGCGGTGTG
GTATGTCGTCGGCGCGCCGG

Product: lipase

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MRSRAVAAAVAFAVSAAPAAGIGTFLSLAGTQAAAAATSAVDNYAATQYPIILVHGLTGTDKYANVLEYWYGIREDLQAH
GAQVYVANLSGFQSDDGPNGRGEQLLAYVQQVLAATGASKVNLIGHSQGGLTSRYVAAVAPQLVASVTTIGTPHRGSEFA
DFVQTVLAYDPTGLSSTVIAAFVNVFGILTSSTNNTNQDALAALKTLTTSQAATYNQNYPSAGLGAPGSCQTGAQTETVG
GNTHLLYSWGGTAIQPTLSILGVTGATDTSTIPVVDPANVLDASTLAMLGSGTVMINRGSGANDGLVSRCSSLYGQVLGT
SYKWNHLDEINQLLGVRGAYAEDPVAVIRTHANRLKTQGV

Sequences:

>Translated_360_residues
MRSRAVAAAVAFAVSAAPAAGIGTFLSLAGTQAAAAATSAVDNYAATQYPIILVHGLTGTDKYANVLEYWYGIREDLQAH
GAQVYVANLSGFQSDDGPNGRGEQLLAYVQQVLAATGASKVNLIGHSQGGLTSRYVAAVAPQLVASVTTIGTPHRGSEFA
DFVQTVLAYDPTGLSSTVIAAFVNVFGILTSSTNNTNQDALAALKTLTTSQAATYNQNYPSAGLGAPGSCQTGAQTETVG
GNTHLLYSWGGTAIQPTLSILGVTGATDTSTIPVVDPANVLDASTLAMLGSGTVMINRGSGANDGLVSRCSSLYGQVLGT
SYKWNHLDEINQLLGVRGAYAEDPVAVIRTHANRLKTQGV
>Mature_360_residues
MRSRAVAAAVAFAVSAAPAAGIGTFLSLAGTQAAAAATSAVDNYAATQYPIILVHGLTGTDKYANVLEYWYGIREDLQAH
GAQVYVANLSGFQSDDGPNGRGEQLLAYVQQVLAATGASKVNLIGHSQGGLTSRYVAAVAPQLVASVTTIGTPHRGSEFA
DFVQTVLAYDPTGLSSTVIAAFVNVFGILTSSTNNTNQDALAALKTLTTSQAATYNQNYPSAGLGAPGSCQTGAQTETVG
GNTHLLYSWGGTAIQPTLSILGVTGATDTSTIPVVDPANVLDASTLAMLGSGTVMINRGSGANDGLVSRCSSLYGQVLGT
SYKWNHLDEINQLLGVRGAYAEDPVAVIRTHANRLKTQGV

Specific function: Catalyzes the hydrolysis of triglycerides [H]

COG id: COG1075

COG function: function code R; Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Pseudomonas lipase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320263, Length=165, Percent_Identity=30.9090909090909, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 36945; Mature: 36945

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSRAVAAAVAFAVSAAPAAGIGTFLSLAGTQAAAAATSAVDNYAATQYPIILVHGLTGT
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCC
DKYANVLEYWYGIREDLQAHGAQVYVANLSGFQSDDGPNGRGEQLLAYVQQVLAATGASK
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCE
VNLIGHSQGGLTSRYVAAVAPQLVASVTTIGTPHRGSEFADFVQTVLAYDPTGLSSTVIA
EEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
AFVNVFGILTSSTNNTNQDALAALKTLTTSQAATYNQNYPSAGLGAPGSCQTGAQTETVG
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEECC
GNTHLLYSWGGTAIQPTLSILGVTGATDTSTIPVVDPANVLDASTLAMLGSGTVMINRGS
CCEEEEEECCCCCCCCCHHEEEECCCCCCCEECCCCCHHHHHHHHHHHHCCCEEEEECCC
GANDGLVSRCSSLYGQVLGTSYKWNHLDEINQLLGVRGAYAEDPVAVIRTHANRLKTQGV
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRSRAVAAAVAFAVSAAPAAGIGTFLSLAGTQAAAAATSAVDNYAATQYPIILVHGLTGT
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCC
DKYANVLEYWYGIREDLQAHGAQVYVANLSGFQSDDGPNGRGEQLLAYVQQVLAATGASK
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCE
VNLIGHSQGGLTSRYVAAVAPQLVASVTTIGTPHRGSEFADFVQTVLAYDPTGLSSTVIA
EEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
AFVNVFGILTSSTNNTNQDALAALKTLTTSQAATYNQNYPSAGLGAPGSCQTGAQTETVG
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEECC
GNTHLLYSWGGTAIQPTLSILGVTGATDTSTIPVVDPANVLDASTLAMLGSGTVMINRGS
CCEEEEEECCCCCCCCCHHEEEECCCCCCCEECCCCCHHHHHHHHHHHHCCCEEEEECCC
GANDGLVSRCSSLYGQVLGTSYKWNHLDEINQLLGVRGAYAEDPVAVIRTHANRLKTQGV
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1987151; 9032073; 9032074 [H]