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The map label for this gene is mxiC [H]

Identifier: 126444754

GI number: 126444754

Start: 2111278

End: 2112399

Strand: Reverse

Name: mxiC [H]

Synonym: BURPS668_A2174

Alternate gene names: 126444754

Gene position: 2112399-2111278 (Counterclockwise)

Preceding gene: 126442335

Following gene: 126444659

Centisome position: 67.54

GC content: 74.6

Gene sequence:

>1122_bases
ATGAGCTCGATCATCGGCGGCGCGTCGGCCGCGCGGCGCGGCTTTTCGATAGACGGCACGGGGAGCGCGGCGAACCGGCT
CGACGCGGAGCCGTCGCTCGACGACGCGCCGCAGACGGCCGCGGCGGGCGCGGCCGACGTGCAGGCGCAACTCGCCGGCG
TCGACGAGGAGGCCGCGAACGCCGCCGCGCAATTCGGCCGGTTCCGCGCGTCGGAGCGCAAGGGGCGGCGCAGCGACGAG
CTCGAACGGATTCTCGACACGGACGCCGACGAGAAGCTCGACGAGCTCGCCGCGCTGCTCGGCGGCCGCGCGGCGCGCGG
CCGCGCGGACCTCGCGACGCTGCTGCGCGACGCGCGCGAGCGCTTTCGCGACGAGAGCGATCTGTTGCTCGCGCTGCGCG
AGCTGCGCCGGCGGCGCCGGCTCGACGGCGAATCCGTCGACGCGCTCGAGCGCGCGATCGACGAGCTGCTCGCGGGCGAC
GGCGCCAAGCGGATCAAGGCGGGCATCAACGCGGCGCTCAAGGCGAAGGTGTTCGGCGCGCGCATGCAGCTCGATGCGCG
CCGGCTGCGCGAGCTGTACCGGCAGTTCCTCGAGTTCGACGGCTCGCACCTCGTCATCTACGAAGACTGGATCGAGCAGT
TCGGCGCGAGCCGCCGCAAGCGGATTCTCGACTACGTGAGCGCCGCGCTGTCGTACGACATGCAGTCGCACGATCCGAGC
TGCGGGTGCGCGGCCGAGTTCGGCCCGCTGCTCGGCACGCTGCATCGCGCGCGCATGCTCGCGTCGGCCGACGAGCAGTT
CGTCGGCCGGCTGCTCGACGACGCGCTCGCGCGCGATTGCGGGCTCACCGAGGCGCGCGCGCTCGCGACGATGCTGGGCG
GCCTGCAACGGCCGTTCTCGGTCGCCGACGTGCTGCTGGGCACGCTCGGCGATCTGCTCGAGCCGCTCGCGCCCGCCCGT
CGCTCGCAGTTGTTGCAGCTCGCGCTGCGCGCGTTCGCGGGCGTGCCGATCGCGCTCTACGGCGACGCCGACGCGCGCCG
CGCGGCGCTCGGCGCGCTCGAGGAGCTGATCGGCGCGACGTATGCGCGCGAGCGGCGGCAGGCGCGCCCGCGCGCCGACT
GA

Upstream 100 bases:

>100_bases
CCTGGCCCGACGGCCAGCCGTGGGAATCGGGCGATCCGGCGGACAACGCGACGCTGCGCGCGACCGTGCAGATGCTCAAA
CCCTACATGGACGACAAGTC

Downstream 100 bases:

>100_bases
CGCGCGGCGCCTTTCATTCAATCCGGTCGATAGTCATGCTGAAGAATCTCCTGATCAAGGCCCAAGCGCGCCCCGAACTG
ATCGTCCTGTGCCTGATGGT

Product: type III secretion regulator YopN/LcrE/InvE/MxiC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MSSIIGGASAARRGFSIDGTGSAANRLDAEPSLDDAPQTAAAGAADVQAQLAGVDEEAANAAAQFGRFRASERKGRRSDE
LERILDTDADEKLDELAALLGGRAARGRADLATLLRDARERFRDESDLLLALRELRRRRRLDGESVDALERAIDELLAGD
GAKRIKAGINAALKAKVFGARMQLDARRLRELYRQFLEFDGSHLVIYEDWIEQFGASRRKRILDYVSAALSYDMQSHDPS
CGCAAEFGPLLGTLHRARMLASADEQFVGRLLDDALARDCGLTEARALATMLGGLQRPFSVADVLLGTLGDLLEPLAPAR
RSQLLQLALRAFAGVPIALYGDADARRAALGALEELIGATYARERRQARPRAD

Sequences:

>Translated_373_residues
MSSIIGGASAARRGFSIDGTGSAANRLDAEPSLDDAPQTAAAGAADVQAQLAGVDEEAANAAAQFGRFRASERKGRRSDE
LERILDTDADEKLDELAALLGGRAARGRADLATLLRDARERFRDESDLLLALRELRRRRRLDGESVDALERAIDELLAGD
GAKRIKAGINAALKAKVFGARMQLDARRLRELYRQFLEFDGSHLVIYEDWIEQFGASRRKRILDYVSAALSYDMQSHDPS
CGCAAEFGPLLGTLHRARMLASADEQFVGRLLDDALARDCGLTEARALATMLGGLQRPFSVADVLLGTLGDLLEPLAPAR
RSQLLQLALRAFAGVPIALYGDADARRAALGALEELIGATYARERRQARPRAD
>Mature_372_residues
SSIIGGASAARRGFSIDGTGSAANRLDAEPSLDDAPQTAAAGAADVQAQLAGVDEEAANAAAQFGRFRASERKGRRSDEL
ERILDTDADEKLDELAALLGGRAARGRADLATLLRDARERFRDESDLLLALRELRRRRRLDGESVDALERAIDELLAGDG
AKRIKAGINAALKAKVFGARMQLDARRLRELYRQFLEFDGSHLVIYEDWIEQFGASRRKRILDYVSAALSYDMQSHDPSC
GCAAEFGPLLGTLHRARMLASADEQFVGRLLDDALARDCGLTEARALATMLGGLQRPFSVADVLLGTLGDLLEPLAPARR
SQLLQLALRAFAGVPIALYGDADARRAALGALEELIGATYARERRQARPRAD

Specific function: Necessary for the secretion of IPA invasins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell (Probable). Note=Secreted via Mxi-Spa type III secretion system (TTSS), and delivered into the host cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010812
- InterPro:   IPR003520
- InterPro:   IPR013401 [H]

Pfam domain/function: PF07201 HrpJ [H]

EC number: NA

Molecular weight: Translated: 40427; Mature: 40296

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIIGGASAARRGFSIDGTGSAANRLDAEPSLDDAPQTAAAGAADVQAQLAGVDEEAAN
CCCCCCCHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCHHHHH
AAAQFGRFRASERKGRRSDELERILDTDADEKLDELAALLGGRAARGRADLATLLRDARE
HHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
RFRDESDLLLALRELRRRRRLDGESVDALERAIDELLAGDGAKRIKAGINAALKAKVFGA
HHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RMQLDARRLRELYRQFLEFDGSHLVIYEDWIEQFGASRRKRILDYVSAALSYDMQSHDPS
HHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCC
CGCAAEFGPLLGTLHRARMLASADEQFVGRLLDDALARDCGLTEARALATMLGGLQRPFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHH
VADVLLGTLGDLLEPLAPARRSQLLQLALRAFAGVPIALYGDADARRAALGALEELIGAT
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHH
YARERRQARPRAD
HHHHHHHCCCCCC
>Mature Secondary Structure 
SSIIGGASAARRGFSIDGTGSAANRLDAEPSLDDAPQTAAAGAADVQAQLAGVDEEAAN
CCCCCCHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCHHHHH
AAAQFGRFRASERKGRRSDELERILDTDADEKLDELAALLGGRAARGRADLATLLRDARE
HHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
RFRDESDLLLALRELRRRRRLDGESVDALERAIDELLAGDGAKRIKAGINAALKAKVFGA
HHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RMQLDARRLRELYRQFLEFDGSHLVIYEDWIEQFGASRRKRILDYVSAALSYDMQSHDPS
HHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCC
CGCAAEFGPLLGTLHRARMLASADEQFVGRLLDDALARDCGLTEARALATMLGGLQRPFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHH
VADVLLGTLGDLLEPLAPARRSQLLQLALRAFAGVPIALYGDADARRAALGALEELIGAT
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHH
YARERRQARPRAD
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11115111; 11292750; 12384590; 8437520; 1639496 [H]