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The map label for this gene is mxiA [H]

Identifier: 126444659

GI number: 126444659

Start: 2109170

End: 2111242

Strand: Reverse

Name: mxiA [H]

Synonym: BURPS668_A2173

Alternate gene names: 126444659

Gene position: 2111242-2109170 (Counterclockwise)

Preceding gene: 126444754

Following gene: 126443908

Centisome position: 67.51

GC content: 66.43

Gene sequence:

>2073_bases
ATGCTGAAGAATCTCCTGATCAAGGCCCAAGCGCGCCCCGAACTGATCGTCCTGTGCCTGATGGTGCTCGTGATCGCGAT
GCTGATCGTGCCGCTGCCGCCGTACGTGCTCGATTTCCTGATCGGCCTGAACATCGTGACGGCGCTGCTCGTGTTCATGG
GCTCGTTCTACATCGTCAACATCCTCGAGTTCTCGACGTTTCCGCCGATCCTGCTGATCACGACGCTGTTCCGGCTCGCG
CTGTCGATCAGCACGAGCCGGATGATCCTGCTCACCGCCGAGGGCGGCAAGATCATCACGACGTTCGGGCAGTTCGTGAT
CGGCGATAACCTCGTGGTCGGCTTCGTCGTGTTCGTGATCGTGACGATCGTGCAGTTCATCGTGATCACGAAGGGCTCGG
AGCGCGTCGCCGAAGTCGCGGCGCGCTTCTCGCTCGACGCGATGCCCGGCAAGCAGATGAGCATCGACGCGGACCTGCGC
GCCGGCATCATCGACAACGAAGGCGTGAAGGCGCGCCGCTCGGCGCTCGAGCGTGAAAGCCAGCTGTACGGCTCGTTCGA
CGGCGCGATGAAGTTCATCAAGGGCGATGCGATCGCCGGCATCGTCGTCATCTTCGTGAACCTGATCGGCGGCATCTCGG
TCGGCGTGATGCAGCACGGCATGTCGGTGTCCGACGCGCTCACGACCTACACGATCCTGTCGATCGGCGACGGCCTCGTC
GCGCAGATCCCGGCGCTCCTGATCGCGATCGGCGCGGGCTTCGTCGTCACCCGCGTGGGCGGCTCGGGCAACAACCTCGG
CGCGAACATCGTCGGCGAGCTGTTCTCGAACCCGTTCGTGCTCGTCGTCACGGCCGTGCTCGCGCTCGCGATCGGCCTGC
TGCCCGGCTTTCCGCTGATCGTCTTCCTGCTGATCGCGCTCGCGCTCGGCGCGCTGTACGTGCGCCGCGAATGGCGCAAG
CCGGGCGAGCCGGCGCGCGAGGGCGGGCTCGTCGGCAAGGTCGCGGGCGCGCTCTCGGGCGGCGGCGCGGCGAAAGCGGC
CGACGGCGGCGCCGGCGATGTCGACATCGACAAGCTGATTCCGGAGACGGTGCCGCTGATGCTGATGGTGCCCGAGGCGG
CGCAGCCGATGTTCGAGCAGGAAGGCGTGATCGGCGCGTTCCGGCGGCGCGCGTTCGTCGACATGGGGCTGCGCCTGCCC
GATATCCGCGTCGTGTATTCGCCGCAGGTGCATCCGCGCGAGGCGATCGTGCTGATCAACGAGATCCGCGCGGCGACGTT
CGCGATCTGCTTCGACCGGCACCGCGTGGTCGGCTCGACGCTCGCGCTCGAAGGGCTGCCCGTCGATGTCGTGACGCTGC
CGGACGGCGCGGGCGGCGACGCGTGGTGGGTGCCGGGCGCGCAGACCGACGCGCTCGCGAAGATCGACGTGCTCACGCGC
TCGGCGATCGACGATCTGTACGGGCAGTTTCTCGCGGTGATGCTCGCCAACGTATCGGAATTCTTCGGCGTGCAGGAGGC
CAAGCGCCTGCTCGACGACATGGACCAGAAGTACCCGGAGCTCATCAAGGAGAGCTATCGGCACATTTCGGTGCAGCGCA
TCGCGGAGGTGTTCCAGCGCCTGCTCGCCGAGAAGATCTCGATTCGCAACATGAAGCTGATTCTCGAATCGCTCGCGCAA
TGGGGGCCGAAGGAGAAGGATTCGATCCTGCTCGTCGAGCACGTGCGCGCGGCGCTCGCGCGCTACATCTCGAACCGCTT
CGCCGCGGGCGGCAAGCTGCGCGCGCTCGTGCTGTCGGCGCAGTTCGAGGACGCGGTGGGCAAGGGCGTGCGGCAGACCT
CGGGCGGCGCGTATCTGAACCTGGAGCCCGCGACGAGCGAGCAACTGCTCGACCGGCTCGCGCTCGAGCTCGCGCGCGCG
GGCTTCTCGCAGCGCGACATGGTGCTGCTTGCCTCGATGGAAGTCAGGCGTTTCGTCAAGCGGCTGATCGAGAGCCGCTT
TCCGGAACTGGAGGTGCTGTCGTTCGGCGAAGTGGCCGACAGCGTCGCAATCGATGTGTTGAAGACGATCTAA

Upstream 100 bases:

>100_bases
TCGAGGAGCTGATCGGCGCGACGTATGCGCGCGAGCGGCGGCAGGCGCGCCCGCGCGCCGACTGACGCGCGGCGCCTTTC
ATTCAATCCGGTCGATAGTC

Downstream 100 bases:

>100_bases
GGAGAGAAGCGATGAACGTCGATGTCGTCATGCTCGTGAAGGAAAGCATGGAGAAGATGGACTGCGGCAACGCGATCGCG
GGCGAGCTGGATGCGCACGC

Product: HrcV family type III secretion protein

Products: NA

Alternate protein names: Protein virH [H]

Number of amino acids: Translated: 690; Mature: 690

Protein sequence:

>690_residues
MLKNLLIKAQARPELIVLCLMVLVIAMLIVPLPPYVLDFLIGLNIVTALLVFMGSFYIVNILEFSTFPPILLITTLFRLA
LSISTSRMILLTAEGGKIITTFGQFVIGDNLVVGFVVFVIVTIVQFIVITKGSERVAEVAARFSLDAMPGKQMSIDADLR
AGIIDNEGVKARRSALERESQLYGSFDGAMKFIKGDAIAGIVVIFVNLIGGISVGVMQHGMSVSDALTTYTILSIGDGLV
AQIPALLIAIGAGFVVTRVGGSGNNLGANIVGELFSNPFVLVVTAVLALAIGLLPGFPLIVFLLIALALGALYVRREWRK
PGEPAREGGLVGKVAGALSGGGAAKAADGGAGDVDIDKLIPETVPLMLMVPEAAQPMFEQEGVIGAFRRRAFVDMGLRLP
DIRVVYSPQVHPREAIVLINEIRAATFAICFDRHRVVGSTLALEGLPVDVVTLPDGAGGDAWWVPGAQTDALAKIDVLTR
SAIDDLYGQFLAVMLANVSEFFGVQEAKRLLDDMDQKYPELIKESYRHISVQRIAEVFQRLLAEKISIRNMKLILESLAQ
WGPKEKDSILLVEHVRAALARYISNRFAAGGKLRALVLSAQFEDAVGKGVRQTSGGAYLNLEPATSEQLLDRLALELARA
GFSQRDMVLLASMEVRRFVKRLIESRFPELEVLSFGEVADSVAIDVLKTI

Sequences:

>Translated_690_residues
MLKNLLIKAQARPELIVLCLMVLVIAMLIVPLPPYVLDFLIGLNIVTALLVFMGSFYIVNILEFSTFPPILLITTLFRLA
LSISTSRMILLTAEGGKIITTFGQFVIGDNLVVGFVVFVIVTIVQFIVITKGSERVAEVAARFSLDAMPGKQMSIDADLR
AGIIDNEGVKARRSALERESQLYGSFDGAMKFIKGDAIAGIVVIFVNLIGGISVGVMQHGMSVSDALTTYTILSIGDGLV
AQIPALLIAIGAGFVVTRVGGSGNNLGANIVGELFSNPFVLVVTAVLALAIGLLPGFPLIVFLLIALALGALYVRREWRK
PGEPAREGGLVGKVAGALSGGGAAKAADGGAGDVDIDKLIPETVPLMLMVPEAAQPMFEQEGVIGAFRRRAFVDMGLRLP
DIRVVYSPQVHPREAIVLINEIRAATFAICFDRHRVVGSTLALEGLPVDVVTLPDGAGGDAWWVPGAQTDALAKIDVLTR
SAIDDLYGQFLAVMLANVSEFFGVQEAKRLLDDMDQKYPELIKESYRHISVQRIAEVFQRLLAEKISIRNMKLILESLAQ
WGPKEKDSILLVEHVRAALARYISNRFAAGGKLRALVLSAQFEDAVGKGVRQTSGGAYLNLEPATSEQLLDRLALELARA
GFSQRDMVLLASMEVRRFVKRLIESRFPELEVLSFGEVADSVAIDVLKTI
>Mature_690_residues
MLKNLLIKAQARPELIVLCLMVLVIAMLIVPLPPYVLDFLIGLNIVTALLVFMGSFYIVNILEFSTFPPILLITTLFRLA
LSISTSRMILLTAEGGKIITTFGQFVIGDNLVVGFVVFVIVTIVQFIVITKGSERVAEVAARFSLDAMPGKQMSIDADLR
AGIIDNEGVKARRSALERESQLYGSFDGAMKFIKGDAIAGIVVIFVNLIGGISVGVMQHGMSVSDALTTYTILSIGDGLV
AQIPALLIAIGAGFVVTRVGGSGNNLGANIVGELFSNPFVLVVTAVLALAIGLLPGFPLIVFLLIALALGALYVRREWRK
PGEPAREGGLVGKVAGALSGGGAAKAADGGAGDVDIDKLIPETVPLMLMVPEAAQPMFEQEGVIGAFRRRAFVDMGLRLP
DIRVVYSPQVHPREAIVLINEIRAATFAICFDRHRVVGSTLALEGLPVDVVTLPDGAGGDAWWVPGAQTDALAKIDVLTR
SAIDDLYGQFLAVMLANVSEFFGVQEAKRLLDDMDQKYPELIKESYRHISVQRIAEVFQRLLAEKISIRNMKLILESLAQ
WGPKEKDSILLVEHVRAALARYISNRFAAGGKLRALVLSAQFEDAVGKGVRQTSGGAYLNLEPATSEQLLDRLALELARA
GFSQRDMVLLASMEVRRFVKRLIESRFPELEVLSFGEVADSVAIDVLKTI

Specific function: Necessary for the secretion of IPA invasins [H]

COG id: COG4789

COG function: function code U; Type III secretory pathway, component EscV

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=689, Percent_Identity=35.9941944847605, Blast_Score=360, Evalue=1e-100,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001712
- InterPro:   IPR006302 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74418; Mature: 74418

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKNLLIKAQARPELIVLCLMVLVIAMLIVPLPPYVLDFLIGLNIVTALLVFMGSFYIVN
CCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILEFSTFPPILLITTLFRLALSISTSRMILLTAEGGKIITTFGQFVIGDNLVVGFVVFVI
HHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEHHHHHHCCCHHHHHHHHHH
VTIVQFIVITKGSERVAEVAARFSLDAMPGKQMSIDADLRAGIIDNEGVKARRSALERES
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEECCHHHCCCCCCCCHHHHHHHHHHHH
QLYGSFDGAMKFIKGDAIAGIVVIFVNLIGGISVGVMQHGMSVSDALTTYTILSIGDGLV
HHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHH
AQIPALLIAIGAGFVVTRVGGSGNNLGANIVGELFSNPFVLVVTAVLALAIGLLPGFPLI
HHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHH
VFLLIALALGALYVRREWRKPGEPAREGGLVGKVAGALSGGGAAKAADGGAGDVDIDKLI
HHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHC
PETVPLMLMVPEAAQPMFEQEGVIGAFRRRAFVDMGLRLPDIRVVYSPQVHPREAIVLIN
CCCCCEEEECCHHHCCHHHHCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHH
EIRAATFAICFDRHRVVGSTLALEGLPVDVVTLPDGAGGDAWWVPGAQTDALAKIDVLTR
HHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCCCEECCCCCCCHHHHHHHHHH
SAIDDLYGQFLAVMLANVSEFFGVQEAKRLLDDMDQKYPELIKESYRHISVQRIAEVFQR
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAEKISIRNMKLILESLAQWGPKEKDSILLVEHVRAALARYISNRFAAGGKLRALVLSA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEEH
QFEDAVGKGVRQTSGGAYLNLEPATSEQLLDRLALELARAGFSQRDMVLLASMEVRRFVK
HHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
RLIESRFPELEVLSFGEVADSVAIDVLKTI
HHHHCCCCCEEEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKNLLIKAQARPELIVLCLMVLVIAMLIVPLPPYVLDFLIGLNIVTALLVFMGSFYIVN
CCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILEFSTFPPILLITTLFRLALSISTSRMILLTAEGGKIITTFGQFVIGDNLVVGFVVFVI
HHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEHHHHHHCCCHHHHHHHHHH
VTIVQFIVITKGSERVAEVAARFSLDAMPGKQMSIDADLRAGIIDNEGVKARRSALERES
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEECCHHHCCCCCCCCHHHHHHHHHHHH
QLYGSFDGAMKFIKGDAIAGIVVIFVNLIGGISVGVMQHGMSVSDALTTYTILSIGDGLV
HHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHH
AQIPALLIAIGAGFVVTRVGGSGNNLGANIVGELFSNPFVLVVTAVLALAIGLLPGFPLI
HHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHH
VFLLIALALGALYVRREWRKPGEPAREGGLVGKVAGALSGGGAAKAADGGAGDVDIDKLI
HHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHC
PETVPLMLMVPEAAQPMFEQEGVIGAFRRRAFVDMGLRLPDIRVVYSPQVHPREAIVLIN
CCCCCEEEECCHHHCCHHHHCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHH
EIRAATFAICFDRHRVVGSTLALEGLPVDVVTLPDGAGGDAWWVPGAQTDALAKIDVLTR
HHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCCCEECCCCCCCHHHHHHHHHH
SAIDDLYGQFLAVMLANVSEFFGVQEAKRLLDDMDQKYPELIKESYRHISVQRIAEVFQR
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAEKISIRNMKLILESLAQWGPKEKDSILLVEHVRAALARYISNRFAAGGKLRALVLSA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEEH
QFEDAVGKGVRQTSGGAYLNLEPATSEQLLDRLALELARAGFSQRDMVLLASMEVRRFVK
HHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
RLIESRFPELEVLSFGEVADSVAIDVLKTI
HHHHCCCCCEEEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1639496; 11115111; 11292750; 12384590; 1312536; 8385666 [H]