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The map label for this gene is mocR [H]

Identifier: 126444581

GI number: 126444581

Start: 1029561

End: 1031096

Strand: Reverse

Name: mocR [H]

Synonym: BURPS668_A1071

Alternate gene names: 126444581

Gene position: 1031096-1029561 (Counterclockwise)

Preceding gene: 126442437

Following gene: 126445246

Centisome position: 32.97

GC content: 73.24

Gene sequence:

>1536_bases
ATGCGATTACTGAATTTTGGAGCCACGATGGACTACGGTGTGTTGCTGTCGAACTTCGAACGGGACACCGCGCGCGACGC
GCTCGCGCGCGCGTCGCAGCAGCACCGGCTCTACGCGTGCCTGCGCGCGGCGATCCTGAACGGCACGCTCGAAGCCGGCA
CGTATCTGATGTCGTCGCGCGCGCTCGCCGAGACGCTGCGGATCGCGCGCAACACGGTGCTCTATGCCTACGAGCGGCTC
GCCGCCGAGGGCTTCGTCGTCGCGCGGCGGCAAGGCACGATGGTCGCGCGTGTGGGGCTGCCCGCGGCGAGCGCGACCGC
CTCGCCCACGCACGCGCGGCCCTCGCTCGCGCGGCGCGTCACCGGGCTGCCGGACATCGACGCCGACGACGAGCGCGAGC
CGCTGCCGTTCCTGCCGGGCATGCCCGCGCTCGACCAGTTTCCGCTCGCGCCGTGGCGGCGCGCGGTCGAGCGCGCATGG
CGGCGAATCGGTCCGGCGCAGCTCGGTCACGCGCCGCTCGGCGGCAATCTGCGGCTGCGGCAGGCGATCGCCGAATATCT
GCGCGTGTCGCGCGGCATCGGCTGCGATGCGCAGCAGGTGTTCATCACCGACGGCACGCAGCACGGCCTCGATCTGTGCG
CGCGCACGCTCGCCGACGCGGGCGATACCGTCTGGATCGAGCATCCCGGCTACGCCGGCGCGCGCGCCGCGTTCGAGGCG
GCCGACCTGCGGCTCGTGCCGATCCCCGTCGATGCGGACGGCCTCGCGCCGAGCGCCGAGCACTGGCGTGCGCATCCGCC
GCGGCTTGTCTACATCACGCCGTCGCACCAGTATCCGCTCGGCGCGGTGATGAGCGTGGAGCGGCGCGTCGCGCTCGTCG
CGAACGCGCGCGCGGCGGGCGCGTGGATCGTGGAGGACGATTACGACAGCGAGTTCCGCCACTTCGGCGCGCCGCTCGCC
GCGCTGCAAAGTCTCGGCGACGACGCGCCCGTCGTCTATCTCGGCACGTTCAGCAAGACGATGTTTCCGACGCTGCGCAT
CGGCTTCGTCGTCGCGTCGGCGGCGCTCGCGCCGCAACTGCGTCACACGATCGGCGCGCTCGCGCCGCGCGGGCGCCTTG
CCGAGCAGCTCGCGCTCGCCGACTTCATCGAAGCGGGCCATTTCACCCGGCATCTGCGCCGGATGCGCCGGCTCTACGAA
GAGCGGCGCGACGCACTGCAGGACGCGCTCGCGCGTCATCTCGGCGGCGCGCTGACGGTGTCGGGCGGCGCGGGCGGCAT
GCATCTGTCCGCGCGGCTCGATGCGCCTGTCGCCGACGTCGACGTCGCGCGCGCGGCGCTCGCCCGCGCGATCACCGTGC
GGCCGCTGTCGCGCTTCTGCCTGCCGGGCACCGATCGCGCCGCATACAACGGCCTCGTGCTCGGCTACGGCGCGGTGCCG
ACCGAGCAGATCGACGCTTGCGTGCGGCGGCTCGGCGCCGCGATCGACGATGCGCTGCGCGAGGTGACGCGGGCGCCGCG
CGACGCCGCGAGATGA

Upstream 100 bases:

>100_bases
GGAATCGGCTGCGGTCGAGGTCATCGGCGGGGCTCCTGCATCGGCATGTTCGTTTCGAAGAGCTCGACGATAGAAAATCT
GTGGCACCATGGATAGATCC

Downstream 100 bases:

>100_bases
ACCCCATGGCGGCGCGCGAGCGCGGCGTCTTCGCTTCGTCGGCGGCCACTATCGCCTCTGCAGCCTCTGCAGCCGCCGCG
GCCTCTATCGCCCTTGCAGT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MRLLNFGATMDYGVLLSNFERDTARDALARASQQHRLYACLRAAILNGTLEAGTYLMSSRALAETLRIARNTVLYAYERL
AAEGFVVARRQGTMVARVGLPAASATASPTHARPSLARRVTGLPDIDADDEREPLPFLPGMPALDQFPLAPWRRAVERAW
RRIGPAQLGHAPLGGNLRLRQAIAEYLRVSRGIGCDAQQVFITDGTQHGLDLCARTLADAGDTVWIEHPGYAGARAAFEA
ADLRLVPIPVDADGLAPSAEHWRAHPPRLVYITPSHQYPLGAVMSVERRVALVANARAAGAWIVEDDYDSEFRHFGAPLA
ALQSLGDDAPVVYLGTFSKTMFPTLRIGFVVASAALAPQLRHTIGALAPRGRLAEQLALADFIEAGHFTRHLRRMRRLYE
ERRDALQDALARHLGGALTVSGGAGGMHLSARLDAPVADVDVARAALARAITVRPLSRFCLPGTDRAAYNGLVLGYGAVP
TEQIDACVRRLGAAIDDALREVTRAPRDAAR

Sequences:

>Translated_511_residues
MRLLNFGATMDYGVLLSNFERDTARDALARASQQHRLYACLRAAILNGTLEAGTYLMSSRALAETLRIARNTVLYAYERL
AAEGFVVARRQGTMVARVGLPAASATASPTHARPSLARRVTGLPDIDADDEREPLPFLPGMPALDQFPLAPWRRAVERAW
RRIGPAQLGHAPLGGNLRLRQAIAEYLRVSRGIGCDAQQVFITDGTQHGLDLCARTLADAGDTVWIEHPGYAGARAAFEA
ADLRLVPIPVDADGLAPSAEHWRAHPPRLVYITPSHQYPLGAVMSVERRVALVANARAAGAWIVEDDYDSEFRHFGAPLA
ALQSLGDDAPVVYLGTFSKTMFPTLRIGFVVASAALAPQLRHTIGALAPRGRLAEQLALADFIEAGHFTRHLRRMRRLYE
ERRDALQDALARHLGGALTVSGGAGGMHLSARLDAPVADVDVARAALARAITVRPLSRFCLPGTDRAAYNGLVLGYGAVP
TEQIDACVRRLGAAIDDALREVTRAPRDAAR
>Mature_511_residues
MRLLNFGATMDYGVLLSNFERDTARDALARASQQHRLYACLRAAILNGTLEAGTYLMSSRALAETLRIARNTVLYAYERL
AAEGFVVARRQGTMVARVGLPAASATASPTHARPSLARRVTGLPDIDADDEREPLPFLPGMPALDQFPLAPWRRAVERAW
RRIGPAQLGHAPLGGNLRLRQAIAEYLRVSRGIGCDAQQVFITDGTQHGLDLCARTLADAGDTVWIEHPGYAGARAAFEA
ADLRLVPIPVDADGLAPSAEHWRAHPPRLVYITPSHQYPLGAVMSVERRVALVANARAAGAWIVEDDYDSEFRHFGAPLA
ALQSLGDDAPVVYLGTFSKTMFPTLRIGFVVASAALAPQLRHTIGALAPRGRLAEQLALADFIEAGHFTRHLRRMRRLYE
ERRDALQDALARHLGGALTVSGGAGGMHLSARLDAPVADVDVARAALARAITVRPLSRFCLPGTDRAAYNGLVLGYGAVP
TEQIDACVRRLGAAIDDALREVTRAPRDAAR

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=319, Percent_Identity=24.1379310344828, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI33469970, Length=319, Percent_Identity=24.1379310344828, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI1787710, Length=475, Percent_Identity=26.5263157894737, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1790797, Length=464, Percent_Identity=26.2931034482759, Blast_Score=125, Evalue=7e-30,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 55260; Mature: 55260

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLNFGATMDYGVLLSNFERDTARDALARASQQHRLYACLRAAILNGTLEAGTYLMSSR
CCEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ALAETLRIARNTVLYAYERLAAEGFVVARRQGTMVARVGLPAASATASPTHARPSLARRV
HHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHH
TGLPDIDADDEREPLPFLPGMPALDQFPLAPWRRAVERAWRRIGPAQLGHAPLGGNLRLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCHHHH
QAIAEYLRVSRGIGCDAQQVFITDGTQHGLDLCARTLADAGDTVWIEHPGYAGARAAFEA
HHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHH
ADLRLVPIPVDADGLAPSAEHWRAHPPRLVYITPSHQYPLGAVMSVERRVALVANARAAG
CCEEEEEECCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHEECCCCCC
AWIVEDDYDSEFRHFGAPLAALQSLGDDAPVVYLGTFSKTMFPTLRIGFVVASAALAPQL
EEEEECCCCHHHHHHCCHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
RHTIGALAPRGRLAEQLALADFIEAGHFTRHLRRMRRLYEERRDALQDALARHLGGALTV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
SGGAGGMHLSARLDAPVADVDVARAALARAITVRPLSRFCLPGTDRAAYNGLVLGYGAVP
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCCC
TEQIDACVRRLGAAIDDALREVTRAPRDAAR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRLLNFGATMDYGVLLSNFERDTARDALARASQQHRLYACLRAAILNGTLEAGTYLMSSR
CCEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ALAETLRIARNTVLYAYERLAAEGFVVARRQGTMVARVGLPAASATASPTHARPSLARRV
HHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHH
TGLPDIDADDEREPLPFLPGMPALDQFPLAPWRRAVERAWRRIGPAQLGHAPLGGNLRLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCHHHH
QAIAEYLRVSRGIGCDAQQVFITDGTQHGLDLCARTLADAGDTVWIEHPGYAGARAAFEA
HHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHH
ADLRLVPIPVDADGLAPSAEHWRAHPPRLVYITPSHQYPLGAVMSVERRVALVANARAAG
CCEEEEEECCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHEECCCCCC
AWIVEDDYDSEFRHFGAPLAALQSLGDDAPVVYLGTFSKTMFPTLRIGFVVASAALAPQL
EEEEECCCCHHHHHHCCHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
RHTIGALAPRGRLAEQLALADFIEAGHFTRHLRRMRRLYEERRDALQDALARHLGGALTV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
SGGAGGMHLSARLDAPVADVDVARAALARAITVRPLSRFCLPGTDRAAYNGLVLGYGAVP
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCCC
TEQIDACVRRLGAAIDDALREVTRAPRDAAR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]