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The map label for this gene is aldH [H]

Identifier: 126444577

GI number: 126444577

Start: 532249

End: 533841

Strand: Reverse

Name: aldH [H]

Synonym: BURPS668_A0566

Alternate gene names: 126444577

Gene position: 533841-532249 (Counterclockwise)

Preceding gene: 126443431

Following gene: 126444556

Centisome position: 17.07

GC content: 75.33

Gene sequence:

>1593_bases
ATGCGACTCACTGGCGAGCTTTTGATCGGCCAATCGGCGACGTTCGGACAACACGGCGCGTTCCGCGCGATCGAGGCGGC
CACGGGCGCGCCGCTCGAGCCGGCGTTCGGCGGCGCGAGCCTGCAGGACCTGGACGCCGCGTGCGCGCTCGCCGACGACG
CGTTCGACGCGTACCGCGAGACGAGCCTCGACGCACGCGCCGCGTTTCTCGACGCGATCGGCCGGCACATCGTCGCGCTC
GGCGACGCGCTGATCGAGCGCTGCGCGGCCGAATCGGGGCTGCCGCGCGCGCGGATCGAAGGCGAGCGCGCGCGCACCGT
CGGGCAGCTCGCGCTGTTCGCGGCCGTCGTGCGCGACGGCGGCTTCATCGACGCGCGCATCGACCCCGCGCGCGCGCAGC
GCAAGCCGCTGCCGCGCGTCGACCTGCGGCTGCGCAATATCGCGATCGGCCCCGTCGCCGTGTTCGGCGCGTCCAATTTT
CCGCTCGCGTTCTCGGTCGCCGGCGGCGACACGGCGTCCGCGCTCGCGGCCGGGTGCCCGGTGATCGTCAAGGCGCACGG
CGCGCATCCCGGCACGTCCGAGCTCGTCGGCCGCGCGATCCAGGCGGCGGTGCGCGAATGCGGGCTGCCGGCGGGCGTGT
TCTCGCTGCTGTTCGACGCGTCGCGCGAGATCGGCCAGGCGCTCGTCGCCGATCCGCGCATCAAGGCGGTCGGCTTCACG
GGCTCGCGGCGCGGCGGCGTCGCGCTGATGCGCATCGCCGCCGCGCGGCCCGAGCCGGTTCCCGTCTACGCCGAGATGAG
CTCGATCAATCCGGTCGTGCTCATGCCCGGCGCGCTCGCCGCGCGGCACGACGCGATCGCGCAGCAGTTCGTCGCGTCGC
TCACGCTCGGCGCGGGCCAGTTCTGCACGAATCCGGGGCTGATTCTCGCGATCGACGGCCCGGCGCTGCGCGCGTTCGAG
AAGGCCGCGGCGGCCGCGATCGACGCCGCCGCCGCGCAGACGATGCTCACGCCGCCCATCCACGCGAGCTACCGCGAGGG
CGTCGCGCGGCTCGCGTCGCACCGCGCGGTCGAGCGGCTCGGCGAAGGCCCCGCCGGCGGGCCCTTCGCCGCGCGCGCCG
CGCTGTTCGCGACGACGGCCGACGCGTTGCTCTCGCACGCCGAGTTGCGCGACGAAGTGTTCGGCCCCGCGTCGCTCGTC
GTGCGCTGCGCGGATGCCGACGCGCTGCACCGCGTGCTGAAGTCGCTCGAAGGCCAGCTGACGATCGCCGCGCATCTCGG
CGAGCGCGACGCGCCGCTGTTCGCCGCGCTGCGCCCGACGCTCGAGCGCCGCGCCGGGCGCATCCTCGTGAACGGCTTCG
GCACGGGCGTCGAGGTCGGCCACGCGATGGTGCACGGCGGACCGTTCCCGGCGACGTCGGACCCGCGCACGACGTCGGTC
GGCGCGCGCGCGATCGAGCGCTTCCTGCGGCCGGTGTCGTATCAGGACGTGCCCGACGCGCTGCTGCCCGATGCGCTGCG
CGACGCGAACCCGCTGCGCGTGCCGCAACGCATCGACGGCGCGCTCGCGCCGCGGGAGGCGCGCGATGCATGA

Upstream 100 bases:

>100_bases
GCAGCTCGACGACGACGAGAACTGACGCGCGGCGCGAGCGCATCCGCTTTTTCAACGGCCGCGCGGCGACGCGCGGCCCG
CACTTTCTGCGAGGAGAACC

Downstream 100 bases:

>100_bases
TCGGCCAGACCTCGCGCGGCCGGACGTCGTCCTGTCGCTCGACGACGTGCGCGCGCTCGCGCTGCGCGTGCTCGCGCACC
ACGGGCTGTCCGACGCGCAC

Product: aldehyde dehydrogenase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MRLTGELLIGQSATFGQHGAFRAIEAATGAPLEPAFGGASLQDLDAACALADDAFDAYRETSLDARAAFLDAIGRHIVAL
GDALIERCAAESGLPRARIEGERARTVGQLALFAAVVRDGGFIDARIDPARAQRKPLPRVDLRLRNIAIGPVAVFGASNF
PLAFSVAGGDTASALAAGCPVIVKAHGAHPGTSELVGRAIQAAVRECGLPAGVFSLLFDASREIGQALVADPRIKAVGFT
GSRRGGVALMRIAAARPEPVPVYAEMSSINPVVLMPGALAARHDAIAQQFVASLTLGAGQFCTNPGLILAIDGPALRAFE
KAAAAAIDAAAAQTMLTPPIHASYREGVARLASHRAVERLGEGPAGGPFAARAALFATTADALLSHAELRDEVFGPASLV
VRCADADALHRVLKSLEGQLTIAAHLGERDAPLFAALRPTLERRAGRILVNGFGTGVEVGHAMVHGGPFPATSDPRTTSV
GARAIERFLRPVSYQDVPDALLPDALRDANPLRVPQRIDGALAPREARDA

Sequences:

>Translated_530_residues
MRLTGELLIGQSATFGQHGAFRAIEAATGAPLEPAFGGASLQDLDAACALADDAFDAYRETSLDARAAFLDAIGRHIVAL
GDALIERCAAESGLPRARIEGERARTVGQLALFAAVVRDGGFIDARIDPARAQRKPLPRVDLRLRNIAIGPVAVFGASNF
PLAFSVAGGDTASALAAGCPVIVKAHGAHPGTSELVGRAIQAAVRECGLPAGVFSLLFDASREIGQALVADPRIKAVGFT
GSRRGGVALMRIAAARPEPVPVYAEMSSINPVVLMPGALAARHDAIAQQFVASLTLGAGQFCTNPGLILAIDGPALRAFE
KAAAAAIDAAAAQTMLTPPIHASYREGVARLASHRAVERLGEGPAGGPFAARAALFATTADALLSHAELRDEVFGPASLV
VRCADADALHRVLKSLEGQLTIAAHLGERDAPLFAALRPTLERRAGRILVNGFGTGVEVGHAMVHGGPFPATSDPRTTSV
GARAIERFLRPVSYQDVPDALLPDALRDANPLRVPQRIDGALAPREARDA
>Mature_530_residues
MRLTGELLIGQSATFGQHGAFRAIEAATGAPLEPAFGGASLQDLDAACALADDAFDAYRETSLDARAAFLDAIGRHIVAL
GDALIERCAAESGLPRARIEGERARTVGQLALFAAVVRDGGFIDARIDPARAQRKPLPRVDLRLRNIAIGPVAVFGASNF
PLAFSVAGGDTASALAAGCPVIVKAHGAHPGTSELVGRAIQAAVRECGLPAGVFSLLFDASREIGQALVADPRIKAVGFT
GSRRGGVALMRIAAARPEPVPVYAEMSSINPVVLMPGALAARHDAIAQQFVASLTLGAGQFCTNPGLILAIDGPALRAFE
KAAAAAIDAAAAQTMLTPPIHASYREGVARLASHRAVERLGEGPAGGPFAARAALFATTADALLSHAELRDEVFGPASLV
VRCADADALHRVLKSLEGQLTIAAHLGERDAPLFAALRPTLERRAGRILVNGFGTGVEVGHAMVHGGPFPATSDPRTTSV
GARAIERFLRPVSYQDVPDALLPDALRDANPLRVPQRIDGALAPREARDA

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507229, Length=371, Percent_Identity=25.8760107816712, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI25777721, Length=380, Percent_Identity=25.2631578947368, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1788042, Length=265, Percent_Identity=31.3207547169811, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1787250, Length=269, Percent_Identity=28.6245353159851, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081896, Length=334, Percent_Identity=26.0479041916168, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1786504, Length=324, Percent_Identity=26.5432098765432, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 54935; Mature: 54935

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTGELLIGQSATFGQHGAFRAIEAATGAPLEPAFGGASLQDLDAACALADDAFDAYRE
CCCCCCEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
TSLDARAAFLDAIGRHIVALGDALIERCAAESGLPRARIEGERARTVGQLALFAAVVRDG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHCC
GFIDARIDPARAQRKPLPRVDLRLRNIAIGPVAVFGASNFPLAFSVAGGDTASALAAGCP
CEEEECCCHHHHHCCCCCCHHHEEEEEEECCEEEECCCCCCEEEEECCCCHHHHHHCCCC
VIVKAHGAHPGTSELVGRAIQAAVRECGLPAGVFSLLFDASREIGQALVADPRIKAVGFT
EEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GSRRGGVALMRIAAARPEPVPVYAEMSSINPVVLMPGALAARHDAIAQQFVASLTLGAGQ
CCCCCCHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCC
FCTNPGLILAIDGPALRAFEKAAAAAIDAAAAQTMLTPPIHASYREGVARLASHRAVERL
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
GEGPAGGPFAARAALFATTADALLSHAELRDEVFGPASLVVRCADADALHRVLKSLEGQL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCHHHHHHHHHHCCCCE
TIAAHLGERDAPLFAALRPTLERRAGRILVNGFGTGVEVGHAMVHGGPFPATSDPRTTSV
EEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCHHH
GARAIERFLRPVSYQDVPDALLPDALRDANPLRVPQRIDGALAPREARDA
HHHHHHHHHCCCCCCCCCHHHCCHHHCCCCCCCCCHHHCCCCCCCCCCCC
>Mature Secondary Structure
MRLTGELLIGQSATFGQHGAFRAIEAATGAPLEPAFGGASLQDLDAACALADDAFDAYRE
CCCCCCEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
TSLDARAAFLDAIGRHIVALGDALIERCAAESGLPRARIEGERARTVGQLALFAAVVRDG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHCC
GFIDARIDPARAQRKPLPRVDLRLRNIAIGPVAVFGASNFPLAFSVAGGDTASALAAGCP
CEEEECCCHHHHHCCCCCCHHHEEEEEEECCEEEECCCCCCEEEEECCCCHHHHHHCCCC
VIVKAHGAHPGTSELVGRAIQAAVRECGLPAGVFSLLFDASREIGQALVADPRIKAVGFT
EEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GSRRGGVALMRIAAARPEPVPVYAEMSSINPVVLMPGALAARHDAIAQQFVASLTLGAGQ
CCCCCCHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCC
FCTNPGLILAIDGPALRAFEKAAAAAIDAAAAQTMLTPPIHASYREGVARLASHRAVERL
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
GEGPAGGPFAARAALFATTADALLSHAELRDEVFGPASLVVRCADADALHRVLKSLEGQL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCHHHHHHHHHHCCCCE
TIAAHLGERDAPLFAALRPTLERRAGRILVNGFGTGVEVGHAMVHGGPFPATSDPRTTSV
EEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCHHH
GARAIERFLRPVSYQDVPDALLPDALRDANPLRVPQRIDGALAPREARDA
HHHHHHHHHCCCCCCCCCHHHCCHHHCCCCCCCCCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]