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The map label for this gene is pdhR [H]

Identifier: 126444546

GI number: 126444546

Start: 520664

End: 521383

Strand: Reverse

Name: pdhR [H]

Synonym: BURPS668_A0554

Alternate gene names: 126444546

Gene position: 521383-520664 (Counterclockwise)

Preceding gene: 126443791

Following gene: 126445256

Centisome position: 16.67

GC content: 70.14

Gene sequence:

>720_bases
ATGACGTTTCAGCCTGTCGAGTCCTATACCCGCGTGCGCCTGTCCGACGTGGTGTCCGATCAGATCAAGTCGCTCATCTC
GGCGGGCAAGCTGCTGCCCGGCCAGAAGCTGCCGACCGAGCGCGAGCTCGCCGCGCAGCTGAACGTGTCGCGCCCGTCGC
TGCGCGAGGCGCTCGTGCGGCTCGAGGCGGACGGCTTCATCGGCTCGGTCGGGCGCGGCGGCTTCGTCGTCTCGGACATC
ACGGCGCCCGTCGTGTCCAGCCCGCTCGCCGATCTGCTGCTGCAGAACCCCGAGGCGAGCCACGACGTGCTCGAGCTGCG
CCATGGCCTCGAGACGATCTCGACCGCGTACGCGGCCGAGCGCGCGACGCCCGGCGATCTCGCGAAGATCAAGGAGGCAT
TCGACACGCTCGCCGGCCACTCGCTGAAGCACGAGCCGGGCCGGCTCGCCGAGGTCGACGCGAACTTCCACCTCGCGATC
GCCGACGCGACGCACAACGTCGCGCTGATCCACGTGATGCACGGCATCCACGGGCTGCTGCAGGAATCGATGCACAAGTC
GCACCGGCTCGTGAACCACGCGGACGCGATGGAGCGCGCGCTGCTCGAGCAGCACACCGAGATCTACGAGGCGATCGCCG
CGAAGGACCCGGAACGCGCGCGCGCGGCGGCGGAGCGGCACCTGCGCTACGTGCGCGCGCTGTACGAGCAGGCGGCCTGA

Upstream 100 bases:

>100_bases
GGCACGCCCCGGCACGCCCCGGCGCGCGTCGGCCGAAGCGCGTACGAGCCGGCCGCGCGAGCCGGCGCCCGCGCCACCTA
ACCGTCCAGAAGGCCCGTGC

Downstream 100 bases:

>100_bases
CACGCCGCGGCGCGCGCGCCTCGCGGCGCCCGGCCAATGCTACATTGGGGCTTTCGACGAGGAGCCCGCATGTCGCCGGA
CCATCCGTGGAATTCGCTGG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MTFQPVESYTRVRLSDVVSDQIKSLISAGKLLPGQKLPTERELAAQLNVSRPSLREALVRLEADGFIGSVGRGGFVVSDI
TAPVVSSPLADLLLQNPEASHDVLELRHGLETISTAYAAERATPGDLAKIKEAFDTLAGHSLKHEPGRLAEVDANFHLAI
ADATHNVALIHVMHGIHGLLQESMHKSHRLVNHADAMERALLEQHTEIYEAIAAKDPERARAAAERHLRYVRALYEQAA

Sequences:

>Translated_239_residues
MTFQPVESYTRVRLSDVVSDQIKSLISAGKLLPGQKLPTERELAAQLNVSRPSLREALVRLEADGFIGSVGRGGFVVSDI
TAPVVSSPLADLLLQNPEASHDVLELRHGLETISTAYAAERATPGDLAKIKEAFDTLAGHSLKHEPGRLAEVDANFHLAI
ADATHNVALIHVMHGIHGLLQESMHKSHRLVNHADAMERALLEQHTEIYEAIAAKDPERARAAAERHLRYVRALYEQAA
>Mature_238_residues
TFQPVESYTRVRLSDVVSDQIKSLISAGKLLPGQKLPTERELAAQLNVSRPSLREALVRLEADGFIGSVGRGGFVVSDIT
APVVSSPLADLLLQNPEASHDVLELRHGLETISTAYAAERATPGDLAKIKEAFDTLAGHSLKHEPGRLAEVDANFHLAIA
DATHNVALIHVMHGIHGLLQESMHKSHRLVNHADAMERALLEQHTEIYEAIAAKDPERARAAAERHLRYVRALYEQAA

Specific function: Transcriptional repressor for the pyruvate dehydrogenase complex genes aceEF and lpd [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786303, Length=230, Percent_Identity=40, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1790032, Length=223, Percent_Identity=39.0134529147982, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1789353, Length=222, Percent_Identity=31.5315315315315, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1790780, Length=218, Percent_Identity=31.651376146789, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082208, Length=226, Percent_Identity=27.8761061946903, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789621, Length=235, Percent_Identity=27.6595744680851, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI48994955, Length=200, Percent_Identity=28.5, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI87081914, Length=227, Percent_Identity=27.7533039647577, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26113; Mature: 25982

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFQPVESYTRVRLSDVVSDQIKSLISAGKLLPGQKLPTERELAAQLNVSRPSLREALVR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
LEADGFIGSVGRGGFVVSDITAPVVSSPLADLLLQNPEASHDVLELRHGLETISTAYAAE
HHCCCCEECCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
RATPGDLAKIKEAFDTLAGHSLKHEPGRLAEVDANFHLAIADATHNVALIHVMHGIHGLL
CCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHH
QESMHKSHRLVNHADAMERALLEQHTEIYEAIAAKDPERARAAAERHLRYVRALYEQAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TFQPVESYTRVRLSDVVSDQIKSLISAGKLLPGQKLPTERELAAQLNVSRPSLREALVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
LEADGFIGSVGRGGFVVSDITAPVVSSPLADLLLQNPEASHDVLELRHGLETISTAYAAE
HHCCCCEECCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
RATPGDLAKIKEAFDTLAGHSLKHEPGRLAEVDANFHLAIADATHNVALIHVMHGIHGLL
CCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHH
QESMHKSHRLVNHADAMERALLEQHTEIYEAIAAKDPERARAAAERHLRYVRALYEQAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]