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The map label for this gene is bfpB [H]

Identifier: 126443441

GI number: 126443441

Start: 2188622

End: 2190394

Strand: Reverse

Name: bfpB [H]

Synonym: BURPS668_A2257

Alternate gene names: 126443441

Gene position: 2190394-2188622 (Counterclockwise)

Preceding gene: 126443086

Following gene: 126444180

Centisome position: 70.04

GC content: 71.57

Gene sequence:

>1773_bases
ATGCGCGTGCTGTTCGCCATTTCATTGCTGGCCGTCGCATGGCTCGCCGGTTGCACCGGCCTTCGCGGCGGCATCGAGCG
CGACGCGCGGCGCGATTCGAACGAAACCGGCGCGCTGCTCAAGCGCGCATCCGACGGCGACAACAGCGTGCGCTCGCTCG
CGCCCGTCGTCGTCGACAGCGGGCTGTGGGTGTCCGCGGGCACCGTCAAGCTGCGCAACAGCGAGCAGTTGCCGCCGCTG
TTCGACGAGCCGGCGTCGTTCGATCGCTCGGTCGCTTCGTTGTCCGAATTCGCCGAGCAGATCACGCGCCTGACCCAGGT
GCCGACGCAGGTCGCCGCGAGCGCGCAGCAGGCGGCCGCGCGTTCACAGCACGGCGGCGCGGGCGACGCCGCGCGCGGCG
CGCCGGCCTTTCTCGACGCATCGGGCGCGCGCGCGGTGCCGCCGCTGCCCCCCGGCCTGCCGGGCGGCGCATCGGCGGGC
GGCGGCAAGACGGGCGGCGGCGCGGCGGGCGCGGGCTCGGAGGGCGGCGGCGGCACGTCGTTCGCGCCGGTGCGCGTGCT
GTACGCGGGCGGCACGCTGCGCGGCCTGCTCGACGCGGCCTGCGCGCGCTTCGGCGTGTCCTGGAAGTACGAGCAGGGGG
CGATCCGCTTCTTCTTCACCGATACCCGCACGTTCCAGGTCAACGCGATTCCGGGCGACTCGTCGCTGAACGCATCGGTC
GTGAGCGGCGCGACGAGCGACGGCGCCGCGGGCGGCTCGCAGTCGGGCGGCTCGGGGGGCTCGGGCGGCGGCATCAACGG
CGCGGGCTCCGGCACGACGGGCCTCACCGCGAACAACACGGCGAACACCGCGGTGAACTCGCAGCTGTCGGTGTTCAATG
GCCTGCAAAGCGCGATCCAATCGATGCTCTCGCGCTACGGCAGCTCGGTCGCCTCGCCCGCGACGGGATCGATCTCGGTG
ACCGACACGCCCGACGTGCTCGAGCGCGTCGCCGCGTTCATGGCGCAGCAGAACCGCTCGCTGTCGCGGCAGGTGCTGCT
CAACGTGACCGTGCTCAGCGTGTCGCTGCAGGCGGGCGACGCGTACGGGATCGACTGGAACCTCGTCTACAAGACGATGT
CCGCGGGGTTCGGCATCACCAATCCGTTCCATCCGACGGCGCTGACGGCGCCCGCCGACATGTCCGCGGCGGTGCTCAGC
CCGACGAGCCGCTTCAACGGCACGAAGCTGCTGATCCGCGCGCTGTCGCAGCAGGGGACGGTGCGGCGCAAGACGTCGGC
GTCGGTCACGACGCTCAACAACCAGCCGGTGCCCGTGCAGGTCGCGACGCAGACGGGCTACCTCGCGTCGGTGTCGACGA
CGAACACCGCGAACGTCGGCTCGTCGACGGCGCTCACGCCGGGCGTCGTGACGACGGGCTTCAACATGACGCTGCTGCCG
CACGTGCTCGACGACGGCACCGTGATGCTGCAGTTCTCGACCAACATCTCGTCGCTGCTCGAGCTGAAGGAGGTGACGAG
CAGCACCGGCGGCAGCGGCCTGGCGCGCATCCAGACGCCCGACGTCGACATGCGCAACTTCCTGCAGCGCGTCGCGATGA
AATCGGGCGAGACGCTCGTCATCAGCGGCTACGAAGGCGCGAACGATTCGCTCGACGAGCGCGGCGTGGGCACGCCGAAG
ATGATCGCGCTCGGCGGCGGCTACGAGGCGCAGCGCGCGCGCGAGGTGATCGTGATCCTGATCACGCCCGTCACGCAGCG
CGGCGGCGCCTGA

Upstream 100 bases:

>100_bases
AGGCGCTCGTCGCGAGCCTCGGCCGAACGTCGACGCCGATCCAGGCGATTCTCTATCGAGGCAATCACGTGTTGCGCGTC
GTCGCGCAAGGAGCGGGCTG

Downstream 100 bases:

>100_bases
CGGAGCCGGCGATGAGCGCGCAGGTGATTCAAATCGGCCGCCAGCGTTTCGTCGGCGGCCTGTTCTGGCAATCGTTGTCG
AGGCGCAACGAGTTGCGCGC

Product: type IVB pilus formation outer membrane protein

Products: NA

Alternate protein names: Bundle-forming pilus B [H]

Number of amino acids: Translated: 590; Mature: 590

Protein sequence:

>590_residues
MRVLFAISLLAVAWLAGCTGLRGGIERDARRDSNETGALLKRASDGDNSVRSLAPVVVDSGLWVSAGTVKLRNSEQLPPL
FDEPASFDRSVASLSEFAEQITRLTQVPTQVAASAQQAAARSQHGGAGDAARGAPAFLDASGARAVPPLPPGLPGGASAG
GGKTGGGAAGAGSEGGGGTSFAPVRVLYAGGTLRGLLDAACARFGVSWKYEQGAIRFFFTDTRTFQVNAIPGDSSLNASV
VSGATSDGAAGGSQSGGSGGSGGGINGAGSGTTGLTANNTANTAVNSQLSVFNGLQSAIQSMLSRYGSSVASPATGSISV
TDTPDVLERVAAFMAQQNRSLSRQVLLNVTVLSVSLQAGDAYGIDWNLVYKTMSAGFGITNPFHPTALTAPADMSAAVLS
PTSRFNGTKLLIRALSQQGTVRRKTSASVTTLNNQPVPVQVATQTGYLASVSTTNTANVGSSTALTPGVVTTGFNMTLLP
HVLDDGTVMLQFSTNISSLLELKEVTSSTGGSGLARIQTPDVDMRNFLQRVAMKSGETLVISGYEGANDSLDERGVGTPK
MIALGGGYEAQRAREVIVILITPVTQRGGA

Sequences:

>Translated_590_residues
MRVLFAISLLAVAWLAGCTGLRGGIERDARRDSNETGALLKRASDGDNSVRSLAPVVVDSGLWVSAGTVKLRNSEQLPPL
FDEPASFDRSVASLSEFAEQITRLTQVPTQVAASAQQAAARSQHGGAGDAARGAPAFLDASGARAVPPLPPGLPGGASAG
GGKTGGGAAGAGSEGGGGTSFAPVRVLYAGGTLRGLLDAACARFGVSWKYEQGAIRFFFTDTRTFQVNAIPGDSSLNASV
VSGATSDGAAGGSQSGGSGGSGGGINGAGSGTTGLTANNTANTAVNSQLSVFNGLQSAIQSMLSRYGSSVASPATGSISV
TDTPDVLERVAAFMAQQNRSLSRQVLLNVTVLSVSLQAGDAYGIDWNLVYKTMSAGFGITNPFHPTALTAPADMSAAVLS
PTSRFNGTKLLIRALSQQGTVRRKTSASVTTLNNQPVPVQVATQTGYLASVSTTNTANVGSSTALTPGVVTTGFNMTLLP
HVLDDGTVMLQFSTNISSLLELKEVTSSTGGSGLARIQTPDVDMRNFLQRVAMKSGETLVISGYEGANDSLDERGVGTPK
MIALGGGYEAQRAREVIVILITPVTQRGGA
>Mature_590_residues
MRVLFAISLLAVAWLAGCTGLRGGIERDARRDSNETGALLKRASDGDNSVRSLAPVVVDSGLWVSAGTVKLRNSEQLPPL
FDEPASFDRSVASLSEFAEQITRLTQVPTQVAASAQQAAARSQHGGAGDAARGAPAFLDASGARAVPPLPPGLPGGASAG
GGKTGGGAAGAGSEGGGGTSFAPVRVLYAGGTLRGLLDAACARFGVSWKYEQGAIRFFFTDTRTFQVNAIPGDSSLNASV
VSGATSDGAAGGSQSGGSGGSGGGINGAGSGTTGLTANNTANTAVNSQLSVFNGLQSAIQSMLSRYGSSVASPATGSISV
TDTPDVLERVAAFMAQQNRSLSRQVLLNVTVLSVSLQAGDAYGIDWNLVYKTMSAGFGITNPFHPTALTAPADMSAAVLS
PTSRFNGTKLLIRALSQQGTVRRKTSASVTTLNNQPVPVQVATQTGYLASVSTTNTANVGSSTALTPGVVTTGFNMTLLP
HVLDDGTVMLQFSTNISSLLELKEVTSSTGGSGLARIQTPDVDMRNFLQRVAMKSGETLVISGYEGANDSLDERGVGTPK
MIALGGGYEAQRAREVIVILITPVTQRGGA

Specific function: Is absolutely required for pilus biogenesis, and for EPEC localized adherence and autoaggregation. Acts at a step in the BFP biogenic pathway after production and processing of the structural pilus subunit BfpA [H]

COG id: COG1450

COG function: function code NU; Type II secretory pathway, component PulD

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011514
- InterPro:   IPR004846 [H]

Pfam domain/function: PF00263 Secretin; PF07655 Secretin_N_2 [H]

EC number: NA

Molecular weight: Translated: 59954; Mature: 59954

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLFAISLLAVAWLAGCTGLRGGIERDARRDSNETGALLKRASDGDNSVRSLAPVVVDS
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHCCC
GLWVSAGTVKLRNSEQLPPLFDEPASFDRSVASLSEFAEQITRLTQVPTQVAASAQQAAA
CCEEECCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSQHGGAGDAARGAPAFLDASGARAVPPLPPGLPGGASAGGGKTGGGAAGAGSEGGGGTS
HHCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
FAPVRVLYAGGTLRGLLDAACARFGVSWKYEQGAIRFFFTDTRTFQVNAIPGDSSLNASV
CCEEEEEEECCHHHHHHHHHHHHHCCCEEECCCCEEEEEECCEEEEEEECCCCCCCCCCE
VSGATSDGAAGGSQSGGSGGSGGGINGAGSGTTGLTANNTANTAVNSQLSVFNGLQSAIQ
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCHHHCCHHHHHHHHHHHHH
SMLSRYGSSVASPATGSISVTDTPDVLERVAAFMAQQNRSLSRQVLLNVTVLSVSLQAGD
HHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHEEEEEEEEEEEECCC
AYGIDWNLVYKTMSAGFGITNPFHPTALTAPADMSAAVLSPTSRFNGTKLLIRALSQQGT
CCCCCHHHHHHHHHCCCCCCCCCCCCEECCCCCCCHHEECCCCCCCCHHHHHHHHHHCCC
VRRKTSASVTTLNNQPVPVQVATQTGYLASVSTTNTANVGSSTALTPGVVTTGFNMTLLP
EEECCCCEEEEECCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCCEEHH
HVLDDGTVMLQFSTNISSLLELKEVTSSTGGSGLARIQTPDVDMRNFLQRVAMKSGETLV
HCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEE
ISGYEGANDSLDERGVGTPKMIALGGGYEAQRAREVIVILITPVTQRGGA
EECCCCCCCCCHHCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCCC
>Mature Secondary Structure
MRVLFAISLLAVAWLAGCTGLRGGIERDARRDSNETGALLKRASDGDNSVRSLAPVVVDS
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHCCC
GLWVSAGTVKLRNSEQLPPLFDEPASFDRSVASLSEFAEQITRLTQVPTQVAASAQQAAA
CCEEECCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSQHGGAGDAARGAPAFLDASGARAVPPLPPGLPGGASAGGGKTGGGAAGAGSEGGGGTS
HHCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
FAPVRVLYAGGTLRGLLDAACARFGVSWKYEQGAIRFFFTDTRTFQVNAIPGDSSLNASV
CCEEEEEEECCHHHHHHHHHHHHHCCCEEECCCCEEEEEECCEEEEEEECCCCCCCCCCE
VSGATSDGAAGGSQSGGSGGSGGGINGAGSGTTGLTANNTANTAVNSQLSVFNGLQSAIQ
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCHHHCCHHHHHHHHHHHHH
SMLSRYGSSVASPATGSISVTDTPDVLERVAAFMAQQNRSLSRQVLLNVTVLSVSLQAGD
HHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHEEEEEEEEEEEECCC
AYGIDWNLVYKTMSAGFGITNPFHPTALTAPADMSAAVLSPTSRFNGTKLLIRALSQQGT
CCCCCHHHHHHHHHCCCCCCCCCCCCEECCCCCCCHHEECCCCCCCCHHHHHHHHHHCCC
VRRKTSASVTTLNNQPVPVQVATQTGYLASVSTTNTANVGSSTALTPGVVTTGFNMTLLP
EEECCCCEEEEECCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCCEEHH
HVLDDGTVMLQFSTNISSLLELKEVTSSTGGSGLARIQTPDVDMRNFLQRVAMKSGETLV
HCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEE
ISGYEGANDSLDERGVGTPKMIALGGGYEAQRAREVIVILITPVTQRGGA
EECCCCCCCCCHHCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8626330; 10496929; 8932312 [H]