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The map label for this gene is ctaD [H]

Identifier: 126443199

GI number: 126443199

Start: 118900

End: 120495

Strand: Reverse

Name: ctaD [H]

Synonym: BURPS668_A0137

Alternate gene names: 126443199

Gene position: 120495-118900 (Counterclockwise)

Preceding gene: 126444641

Following gene: 126444629

Centisome position: 3.85

GC content: 63.22

Gene sequence:

>1596_bases
ATGAGCGAGATCTCCACGAACATGCCGCACGTGCGCGACGCCGCGCATCATGCCCCAACCGGCTGGCGCCGCTGGTTGTT
CGCGACGAATCACAAGGACATCGGCACGCTGTATCTGCTGTTCTCGATCGTCAACCTGATGATCGGCGGCGTGATGGCGC
TGATGATTCGCGCCGAGCTGTTCGAGCCCGGCCTGCAACTGATGCGCCCGGAGTTCTTCAATCAGCTGTCGACCGAGCAC
GGCTTCATCATGATCTTCGGCGCGATCATGCCCGCGTTCGTCGGCCTCGCGAACTGGATGATCCCGCTGCAGATCGGCGC
GTCCGACATGGCGTTCGCGCGGATGAACAACTTCAGCTTCTGGCTGCTGCCGGTGTCGAGCGCGCTGCTGATCGGCTCGT
TCTTCGTGCCGGGCGGCGCGCCGGCGGCCGGCTGGACGATGTACGCGCCGCTGTCGACGCAGATGGGCCCGGGCATGGAT
CTGTCGATCTTCGCGATCCACATCGCCGGTGCATCGTCGATCATGGGCGCGATCAACATCGTCGTGACCGTGGTCAACAT
GCGCGCGCCCGGCCTCACGCTGATGAAGATGCCGATGTTCGCGTGGACATGGATCATCACGTCGTTCCTGCTGATCGCGA
TCATGCCGGTGCTCGCGGGCGCGGTGACGATGGTGCTGTTCGACCGGCATTTCGGCACGTCGTTCTTCAACGCGTCGGGC
GGCGGCGATCCGGTGCTGTACCAGCACATCTTCTGGTACTTCGGCCATCCCGAGGTCTACGTGATGATCCTGCCCGGCTT
CGGAATGATCTCGCAGGTGATTCCCGCGTTCTCGCGCAAGCCGCTGTTCGGCTATGCATCGATGGTGTACGCAACCGCGT
CGATCGGCATCCTGTCGTTCATGGTCTGGGCGCACCACATGTTCGTCACGGGAATGCCGGTGGCGGGCCAGTTGTTCTTC
ATGTACGCGACGATGACGATCGCCGTGCCCACCGGCGTGAAGGTGTTCAACTGGGTCGCGACGATGTGGCGCGGCTCGCT
CACGTTCGAGACGCCGATGCTGTTCTCGATCGGCTTCATCTTCGTGTTCCTGATCGGCGGGCTGACGGGCGTCACGCTCG
CGATGGCGCCGCTGAACGTCGCGCTGCACGGCACCTATTACATCATCGCGCACTTCCACTACGTGATGGTGGCCGCATCG
CTGTTCAGCATCTATGCGGGCTGGTACTTCTGGGTGCCGAAGTGGACCGGCTATTTCTACGACGAGCGGCGCGGCAGGAT
TCACTTCTGGGGGTCGATGATCTCGTTCAACGTCACGTTCTTCCCGATGCACTTCCTCGGCCTCGCGGGCATGCCGCGCC
GCTATGCGGACTACCCGGCGCAATTCACCGACTTCAATCAGATCGCGACGATCGGCGCGTTCGCGTTCGGGCTGATGCAA
GTGTACTTCCTGTTCTGGGTCGCGCTGCCGACGTACCTCGGCAAGACGCGCCGCTGCGTCGACGCGAAACCGTGGGACGG
CGCGCAGGGGCTCGAATGGACGCTGCCGAGCCCAGCGCCGTACCATTCGTTCGAAACGCCGCCGGCCGTCAAATGA

Upstream 100 bases:

>100_bases
CGAGAGCGGCGAGCGCATCGAATATCGCGGTCGCGACACAGTGCCGACAGCCGGCACAACGGCCCCCATTCCGGATTTTC
GAGAACGAGGCAACGACACA

Downstream 100 bases:

>100_bases
CCGCCCGGCCGCGGACCCGGCGGCACGCGCGCGCACATGCCGATGCCGGCGCCAACGCCAACGCCGATGCCAACGCCGAT
GCCAACGCCGATACCAACGC

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MSEISTNMPHVRDAAHHAPTGWRRWLFATNHKDIGTLYLLFSIVNLMIGGVMALMIRAELFEPGLQLMRPEFFNQLSTEH
GFIMIFGAIMPAFVGLANWMIPLQIGASDMAFARMNNFSFWLLPVSSALLIGSFFVPGGAPAAGWTMYAPLSTQMGPGMD
LSIFAIHIAGASSIMGAINIVVTVVNMRAPGLTLMKMPMFAWTWIITSFLLIAIMPVLAGAVTMVLFDRHFGTSFFNASG
GGDPVLYQHIFWYFGHPEVYVMILPGFGMISQVIPAFSRKPLFGYASMVYATASIGILSFMVWAHHMFVTGMPVAGQLFF
MYATMTIAVPTGVKVFNWVATMWRGSLTFETPMLFSIGFIFVFLIGGLTGVTLAMAPLNVALHGTYYIIAHFHYVMVAAS
LFSIYAGWYFWVPKWTGYFYDERRGRIHFWGSMISFNVTFFPMHFLGLAGMPRRYADYPAQFTDFNQIATIGAFAFGLMQ
VYFLFWVALPTYLGKTRRCVDAKPWDGAQGLEWTLPSPAPYHSFETPPAVK

Sequences:

>Translated_531_residues
MSEISTNMPHVRDAAHHAPTGWRRWLFATNHKDIGTLYLLFSIVNLMIGGVMALMIRAELFEPGLQLMRPEFFNQLSTEH
GFIMIFGAIMPAFVGLANWMIPLQIGASDMAFARMNNFSFWLLPVSSALLIGSFFVPGGAPAAGWTMYAPLSTQMGPGMD
LSIFAIHIAGASSIMGAINIVVTVVNMRAPGLTLMKMPMFAWTWIITSFLLIAIMPVLAGAVTMVLFDRHFGTSFFNASG
GGDPVLYQHIFWYFGHPEVYVMILPGFGMISQVIPAFSRKPLFGYASMVYATASIGILSFMVWAHHMFVTGMPVAGQLFF
MYATMTIAVPTGVKVFNWVATMWRGSLTFETPMLFSIGFIFVFLIGGLTGVTLAMAPLNVALHGTYYIIAHFHYVMVAAS
LFSIYAGWYFWVPKWTGYFYDERRGRIHFWGSMISFNVTFFPMHFLGLAGMPRRYADYPAQFTDFNQIATIGAFAFGLMQ
VYFLFWVALPTYLGKTRRCVDAKPWDGAQGLEWTLPSPAPYHSFETPPAVK
>Mature_530_residues
SEISTNMPHVRDAAHHAPTGWRRWLFATNHKDIGTLYLLFSIVNLMIGGVMALMIRAELFEPGLQLMRPEFFNQLSTEHG
FIMIFGAIMPAFVGLANWMIPLQIGASDMAFARMNNFSFWLLPVSSALLIGSFFVPGGAPAAGWTMYAPLSTQMGPGMDL
SIFAIHIAGASSIMGAINIVVTVVNMRAPGLTLMKMPMFAWTWIITSFLLIAIMPVLAGAVTMVLFDRHFGTSFFNASGG
GDPVLYQHIFWYFGHPEVYVMILPGFGMISQVIPAFSRKPLFGYASMVYATASIGILSFMVWAHHMFVTGMPVAGQLFFM
YATMTIAVPTGVKVFNWVATMWRGSLTFETPMLFSIGFIFVFLIGGLTGVTLAMAPLNVALHGTYYIIAHFHYVMVAASL
FSIYAGWYFWVPKWTGYFYDERRGRIHFWGSMISFNVTFFPMHFLGLAGMPRRYADYPAQFTDFNQIATIGAFAFGLMQV
YFLFWVALPTYLGKTRRCVDAKPWDGAQGLEWTLPSPAPYHSFETPPAVK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=516, Percent_Identity=49.031007751938, Blast_Score=471, Evalue=1e-132,
Organism=Escherichia coli, GI1786634, Length=518, Percent_Identity=40.3474903474903, Blast_Score=367, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6226519, Length=530, Percent_Identity=46.6037735849057, Blast_Score=487, Evalue=1e-138,
Organism=Saccharomyces cerevisiae, GI6226524, Length=323, Percent_Identity=50.7739938080495, Blast_Score=336, Evalue=7e-93,
Organism=Saccharomyces cerevisiae, GI6226523, Length=247, Percent_Identity=46.1538461538462, Blast_Score=216, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59274; Mature: 59143

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
6.8 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEISTNMPHVRDAAHHAPTGWRRWLFATNHKDIGTLYLLFSIVNLMIGGVMALMIRAEL
CCCCCCCCCCHHHHHCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEPGLQLMRPEFFNQLSTEHGFIMIFGAIMPAFVGLANWMIPLQIGASDMAFARMNNFSF
HHCCHHHHCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCEEEEEECCCHHHHHEECCCEE
WLLPVSSALLIGSFFVPGGAPAAGWTMYAPLSTQMGPGMDLSIFAIHIAGASSIMGAINI
EEEEHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCEEEEEEEECCHHHHHHHHHH
VVTVVNMRAPGLTLMKMPMFAWTWIITSFLLIAIMPVLAGAVTMVLFDRHFGTSFFNASG
HHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GGDPVLYQHIFWYFGHPEVYVMILPGFGMISQVIPAFSRKPLFGYASMVYATASIGILSF
CCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
MVWAHHMFVTGMPVAGQLFFMYATMTIAVPTGVKVFNWVATMWRGSLTFETPMLFSIGFI
HHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCEECCHHHHHHHHH
FVFLIGGLTGVTLAMAPLNVALHGTYYIIAHFHYVMVAASLFSIYAGWYFWVPKWTGYFY
HHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEE
DERRGRIHFWGSMISFNVTFFPMHFLGLAGMPRRYADYPAQFTDFNQIATIGAFAFGLMQ
ECCCCEEEEEEEEEEEEEEEHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHH
VYFLFWVALPTYLGKTRRCVDAKPWDGAQGLEWTLPSPAPYHSFETPPAVK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SEISTNMPHVRDAAHHAPTGWRRWLFATNHKDIGTLYLLFSIVNLMIGGVMALMIRAEL
CCCCCCCCCHHHHHCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEPGLQLMRPEFFNQLSTEHGFIMIFGAIMPAFVGLANWMIPLQIGASDMAFARMNNFSF
HHCCHHHHCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCEEEEEECCCHHHHHEECCCEE
WLLPVSSALLIGSFFVPGGAPAAGWTMYAPLSTQMGPGMDLSIFAIHIAGASSIMGAINI
EEEEHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCEEEEEEEECCHHHHHHHHHH
VVTVVNMRAPGLTLMKMPMFAWTWIITSFLLIAIMPVLAGAVTMVLFDRHFGTSFFNASG
HHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GGDPVLYQHIFWYFGHPEVYVMILPGFGMISQVIPAFSRKPLFGYASMVYATASIGILSF
CCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
MVWAHHMFVTGMPVAGQLFFMYATMTIAVPTGVKVFNWVATMWRGSLTFETPMLFSIGFI
HHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCEECCHHHHHHHHH
FVFLIGGLTGVTLAMAPLNVALHGTYYIIAHFHYVMVAASLFSIYAGWYFWVPKWTGYFY
HHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEE
DERRGRIHFWGSMISFNVTFFPMHFLGLAGMPRRYADYPAQFTDFNQIATIGAFAFGLMQ
ECCCCEEEEEEEEEEEEEEEHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHH
VYFLFWVALPTYLGKTRRCVDAKPWDGAQGLEWTLPSPAPYHSFETPPAVK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8117073 [H]