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The map label for this gene is hipO [H]

Identifier: 126442979

GI number: 126442979

Start: 262348

End: 263538

Strand: Reverse

Name: hipO [H]

Synonym: BURPS668_A0295

Alternate gene names: 126442979

Gene position: 263538-262348 (Counterclockwise)

Preceding gene: 126444821

Following gene: 126443821

Centisome position: 8.43

GC content: 69.27

Gene sequence:

>1191_bases
ATGCATTCCGCCCCGTCCGAACACCCCGTCATCCCCGGCATCGCCGCGATCGCGCCCGAGCTGATCGACGTGCGCCGCCG
CATTCACGCGCACCCCGAACTCGCATTCGAGGAGACGCTCACGAGCGATCTCGTCGCCGGGCTGCTCGCCGGCTGGGGCT
ACGACGTGCATCGCGGGCTCGGCAAGACGGGCCTCGTCGGCGTGCTGCGCGAAGGTCAAGGCGCGCGCACGCTCGGCCTG
CGCGCGGACATGGACGCGCTGCCGATCGCCGAGGCAACGGGCCTGCCGTATGCGAGCCGCCGCGCGAACAAGATGCATGC
GTGCGGGCACGACGGCCACACCGCGATGCTGCTGTGCGCGGCGCGCCATCTCGCCGCGACGCGCCGGTTCTCGGGCACGC
TGAACCTCATCTTCCAGCCCGCCGAGGAAAACTTCGGCGGCGCGAAGGCGATGATGGACGACGGCCTGTTCGAGCGCTTT
CCCTGCGACGCGATCTTCGCGATCCACAACATGCCCGGCCGCGCGGCGGGCGACATGGCGTTCCGCACGGGCGCCGCGAT
GGCTTCGTCCGATCGCGTGACGATCACGCTGCGCGGCGTCGGCGGGCACGGCGCGATGCCGCATTTCGCGCGCGATCCGA
TGTCGGCGGCGGGCAGCATCATCGTCGCGCTGCAAACGATCGTCGCGCGCGAAATCGACGCGCAGCAATCGGCCGTGATC
ACCGTCGGCAGCGTGCAGGCCGGCGAGACGTTCAACGTGATTCCCGAGACCGTCGTGATGAAGCTGTCGGTGCGCGCGCT
GAACGCCGACGTGCGCGCGCTGCTCGCGCAGCGCATCGAGGCGCTCGCGAAAGGCCAGGCGCAGAGCTTCGGCATCGAGG
CGGACGTTCAGTATGACTACGGTTATCCGGTGCTCGTCAATCACGACGAGCCGACCGCGTTCGCGATCGACGTTGCGCGC
CGGATGCTCGGCGAGGCGCGCGTCGAAGCGCAAACCGCGCCGCTGATGGGCAGCGAGGATTTCGCGTACATGCTCGAAGC
GCGCCCCGGCTGCTATGCGTTCATCGGCAACGGCGTCGGCAGCAAGGGCGGCTGCATGGTCCACAACCCCGGCTACGACT
TCAACGACGACATCCTCGCGATCGGCGCGAGCTATTGGGTGCGGCTTGCCGAAGCATGGCTCGCCGCCTGA

Upstream 100 bases:

>100_bases
TGAGCACCGACGCAATTTATCAGCTTATGGTGCACAAAAAAAGTTCATATGCTTCGTCGACATGTCGCGCAAGCGCCCCC
AGCCCCCACGAGGAGACAGC

Downstream 100 bases:

>100_bases
TGCGGCGCCGCCGCGCCGTCTCGCGCTCCTCGGGGGTCACATGGAAACGTCCGCTCTCAATTTCGCCGGCGCGCCGGCCG
ACGCGCGCGCCGCCGCAAAG

Product: metal-dependent amidase/aminoacylase/carboxypeptidase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MHSAPSEHPVIPGIAAIAPELIDVRRRIHAHPELAFEETLTSDLVAGLLAGWGYDVHRGLGKTGLVGVLREGQGARTLGL
RADMDALPIAEATGLPYASRRANKMHACGHDGHTAMLLCAARHLAATRRFSGTLNLIFQPAEENFGGAKAMMDDGLFERF
PCDAIFAIHNMPGRAAGDMAFRTGAAMASSDRVTITLRGVGGHGAMPHFARDPMSAAGSIIVALQTIVAREIDAQQSAVI
TVGSVQAGETFNVIPETVVMKLSVRALNADVRALLAQRIEALAKGQAQSFGIEADVQYDYGYPVLVNHDEPTAFAIDVAR
RMLGEARVEAQTAPLMGSEDFAYMLEARPGCYAFIGNGVGSKGGCMVHNPGYDFNDDILAIGASYWVRLAEAWLAA

Sequences:

>Translated_396_residues
MHSAPSEHPVIPGIAAIAPELIDVRRRIHAHPELAFEETLTSDLVAGLLAGWGYDVHRGLGKTGLVGVLREGQGARTLGL
RADMDALPIAEATGLPYASRRANKMHACGHDGHTAMLLCAARHLAATRRFSGTLNLIFQPAEENFGGAKAMMDDGLFERF
PCDAIFAIHNMPGRAAGDMAFRTGAAMASSDRVTITLRGVGGHGAMPHFARDPMSAAGSIIVALQTIVAREIDAQQSAVI
TVGSVQAGETFNVIPETVVMKLSVRALNADVRALLAQRIEALAKGQAQSFGIEADVQYDYGYPVLVNHDEPTAFAIDVAR
RMLGEARVEAQTAPLMGSEDFAYMLEARPGCYAFIGNGVGSKGGCMVHNPGYDFNDDILAIGASYWVRLAEAWLAA
>Mature_396_residues
MHSAPSEHPVIPGIAAIAPELIDVRRRIHAHPELAFEETLTSDLVAGLLAGWGYDVHRGLGKTGLVGVLREGQGARTLGL
RADMDALPIAEATGLPYASRRANKMHACGHDGHTAMLLCAARHLAATRRFSGTLNLIFQPAEENFGGAKAMMDDGLFERF
PCDAIFAIHNMPGRAAGDMAFRTGAAMASSDRVTITLRGVGGHGAMPHFARDPMSAAGSIIVALQTIVAREIDAQQSAVI
TVGSVQAGETFNVIPETVVMKLSVRALNADVRALLAQRIEALAKGQAQSFGIEADVQYDYGYPVLVNHDEPTAFAIDVAR
RMLGEARVEAQTAPLMGSEDFAYMLEARPGCYAFIGNGVGSKGGCMVHNPGYDFNDDILAIGASYWVRLAEAWLAA

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=428, Percent_Identity=27.1028037383178, Blast_Score=95, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 42118; Mature: 42118

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSAPSEHPVIPGIAAIAPELIDVRRRIHAHPELAFEETLTSDLVAGLLAGWGYDVHRGL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCC
GKTGLVGVLREGQGARTLGLRADMDALPIAEATGLPYASRRANKMHACGHDGHTAMLLCA
CCCCHHEEEECCCCCEEECCCCCCCCCCCHHHCCCCHHHHCCCCCCCCCCCCCHHHHHHH
ARHLAATRRFSGTLNLIFQPAEENFGGAKAMMDDGLFERFPCDAIFAIHNMPGRAAGDMA
HHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHCCCHHHCCCCCEEEEECCCCCCCCCHH
FRTGAAMASSDRVTITLRGVGGHGAMPHFARDPMSAAGSIIVALQTIVAREIDAQQSAVI
HHCCCCCCCCCEEEEEEEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
TVGSVQAGETFNVIPETVVMKLSVRALNADVRALLAQRIEALAKGQAQSFGIEADVQYDY
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEEECC
GYPVLVNHDEPTAFAIDVARRMLGEARVEAQTAPLMGSEDFAYMLEARPGCYAFIGNGVG
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCCCC
SKGGCMVHNPGYDFNDDILAIGASYWVRLAEAWLAA
CCCCEEEECCCCCCCCCCEEEHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHSAPSEHPVIPGIAAIAPELIDVRRRIHAHPELAFEETLTSDLVAGLLAGWGYDVHRGL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCC
GKTGLVGVLREGQGARTLGLRADMDALPIAEATGLPYASRRANKMHACGHDGHTAMLLCA
CCCCHHEEEECCCCCEEECCCCCCCCCCCHHHCCCCHHHHCCCCCCCCCCCCCHHHHHHH
ARHLAATRRFSGTLNLIFQPAEENFGGAKAMMDDGLFERFPCDAIFAIHNMPGRAAGDMA
HHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHCCCHHHCCCCCEEEEECCCCCCCCCHH
FRTGAAMASSDRVTITLRGVGGHGAMPHFARDPMSAAGSIIVALQTIVAREIDAQQSAVI
HHCCCCCCCCCEEEEEEEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
TVGSVQAGETFNVIPETVVMKLSVRALNADVRALLAQRIEALAKGQAQSFGIEADVQYDY
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEEECC
GYPVLVNHDEPTAFAIDVARRMLGEARVEAQTAPLMGSEDFAYMLEARPGCYAFIGNGVG
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCCCC
SKGGCMVHNPGYDFNDDILAIGASYWVRLAEAWLAA
CCCCEEEECCCCCCCCCCEEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]