Click here to switch to the map view.

The map label for this gene is hexR [H]

Identifier: 126442790

GI number: 126442790

Start: 1811982

End: 1812926

Strand: Reverse

Name: hexR [H]

Synonym: BURPS668_A1857

Alternate gene names: 126442790

Gene position: 1812926-1811982 (Counterclockwise)

Preceding gene: 126443556

Following gene: 126443384

Centisome position: 57.97

GC content: 75.13

Gene sequence:

>945_bases
ATGCCCAGCTCACCCGCCACGCCGCTTGCCGCCGAGCCGTCGATCGCCGCGCGCATCGCCGCCGCGCTGCCGTCGCTCAC
GCCGATCCATCGGCGCATGGGCGAGTACGTGCTCGCGAATCCGTTCCGCGCGGCGACGATGCGCATCGACGAGCTCGCGA
ACGCGGTGGACGCGTCGGTCGCGACCGCGAACCGCTTCGCGCGCGCGCTCGGCTTCGACGGCTACCCGGCGCTGCGCGCG
GCGCTCGTGCGCGGCTTCGAGGCGACGCTCGCGCCCGTCGAGCGGCTGCGTTGCGCGCAGGAGCGCGAGGCGGGCGCGCG
CGGCGGCGAGCTGATCGACGCGAGCTTCGAGCAGGCGCTCGCGAACCTCGAGCGCACGCGCGGGCGGCTCGATCGCGCGA
ACGCCGAGGCGGCCGTCGATTCGCTGCTCGCCGCACGCCGGATCTTCATCGTCGGGATGGGCGCGAGCGCGTTTCTCGCC
GGCTTGATGGAGCACGGGCTGTCCGTCTACCGCGACAACGTGCAATCGCTCGCGCTGCTCGGCGGGCCGACCGATGCCGC
GCGGCGCCTGTTCAGCGCGCGCGGCGACGATCTCGTCGTCGCGATCGCGTTTCCGCGCTACGTGTACGACACGATCGAGC
TCACGCGGCGCGCGGCCGAGCGCGGCGCGCCCGTGCTCGCGATCACCGACGGGCCCGATTCGCCGATCGCGCCGTTCGCC
GCGCGCGCGCTTTTCGTGCACGCGGAGCGCCGGCTCGCGGCGACCTCCGAGGCCGCGGTGCTCGCGCTCGTCGAGGCGCT
GATCGACGCGGTCGCGCATCGCTCGCAGCGCTCGGCGCGCGCGGCCGCCGAAGTGACCGAATTCATGCTGCCGTGGCTCG
AGGCGCGGGGCGCGTGCGCCGCGCCGCCGCGCCCGCCGCGCCGTTCCAGGAAAACCGACCGATGA

Upstream 100 bases:

>100_bases
CGGACGGGGCCCGTGCAAACCCCGATGAAAATTTATTTTTTCCATTTTGCCAATTGTGTAAATTTACTTTCATCGCCATT
CGATGCAACACCGCCGCCGC

Downstream 100 bases:

>100_bases
CTTCACCCGCAATCGTTGCGATTCACGGCGGCGCAGGCACGATCCTGCGCGAGGCGATGACGGCCGACGCCGAAGCGCAG
TACCGCGCGGAGCTTGCCGC

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MPSSPATPLAAEPSIAARIAAALPSLTPIHRRMGEYVLANPFRAATMRIDELANAVDASVATANRFARALGFDGYPALRA
ALVRGFEATLAPVERLRCAQEREAGARGGELIDASFEQALANLERTRGRLDRANAEAAVDSLLAARRIFIVGMGASAFLA
GLMEHGLSVYRDNVQSLALLGGPTDAARRLFSARGDDLVVAIAFPRYVYDTIELTRRAAERGAPVLAITDGPDSPIAPFA
ARALFVHAERRLAATSEAAVLALVEALIDAVAHRSQRSARAAAEVTEFMLPWLEARGACAAPPRPPRRSRKTDR

Sequences:

>Translated_314_residues
MPSSPATPLAAEPSIAARIAAALPSLTPIHRRMGEYVLANPFRAATMRIDELANAVDASVATANRFARALGFDGYPALRA
ALVRGFEATLAPVERLRCAQEREAGARGGELIDASFEQALANLERTRGRLDRANAEAAVDSLLAARRIFIVGMGASAFLA
GLMEHGLSVYRDNVQSLALLGGPTDAARRLFSARGDDLVVAIAFPRYVYDTIELTRRAAERGAPVLAITDGPDSPIAPFA
ARALFVHAERRLAATSEAAVLALVEALIDAVAHRSQRSARAAAEVTEFMLPWLEARGACAAPPRPPRRSRKTDR
>Mature_313_residues
PSSPATPLAAEPSIAARIAAALPSLTPIHRRMGEYVLANPFRAATMRIDELANAVDASVATANRFARALGFDGYPALRAA
LVRGFEATLAPVERLRCAQEREAGARGGELIDASFEQALANLERTRGRLDRANAEAAVDSLLAARRIFIVGMGASAFLAG
LMEHGLSVYRDNVQSLALLGGPTDAARRLFSARGDDLVVAIAFPRYVYDTIELTRRAAERGAPVLAITDGPDSPIAPFAA
RALFVHAERRLAATSEAAVLALVEALIDAVAHRSQRSARAAAEVTEFMLPWLEARGACAAPPRPPRRSRKTDR

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=220, Percent_Identity=26.3636363636364, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 33512; Mature: 33380

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSPATPLAAEPSIAARIAAALPSLTPIHRRMGEYVLANPFRAATMRIDELANAVDASV
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHH
ATANRFARALGFDGYPALRAALVRGFEATLAPVERLRCAQEREAGARGGELIDASFEQAL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
ANLERTRGRLDRANAEAAVDSLLAARRIFIVGMGASAFLAGLMEHGLSVYRDNVQSLALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHC
GGPTDAARRLFSARGDDLVVAIAFPRYVYDTIELTRRAAERGAPVLAITDGPDSPIAPFA
CCCCHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHH
ARALFVHAERRLAATSEAAVLALVEALIDAVAHRSQRSARAAAEVTEFMLPWLEARGACA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
APPRPPRRSRKTDR
CCCCCCCCCCCCCC
>Mature Secondary Structure 
PSSPATPLAAEPSIAARIAAALPSLTPIHRRMGEYVLANPFRAATMRIDELANAVDASV
CCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHH
ATANRFARALGFDGYPALRAALVRGFEATLAPVERLRCAQEREAGARGGELIDASFEQAL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
ANLERTRGRLDRANAEAAVDSLLAARRIFIVGMGASAFLAGLMEHGLSVYRDNVQSLALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHC
GGPTDAARRLFSARGDDLVVAIAFPRYVYDTIELTRRAAERGAPVLAITDGPDSPIAPFA
CCCCHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHH
ARALFVHAERRLAATSEAAVLALVEALIDAVAHRSQRSARAAAEVTEFMLPWLEARGACA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
APPRPPRRSRKTDR
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]