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The map label for this gene is ahpC [H]

Identifier: 126442391

GI number: 126442391

Start: 724779

End: 725342

Strand: Reverse

Name: ahpC [H]

Synonym: BURPS668_A0757

Alternate gene names: 126442391

Gene position: 725342-724779 (Counterclockwise)

Preceding gene: 126445566

Following gene: 284159994

Centisome position: 23.19

GC content: 62.94

Gene sequence:

>564_bases
ATGCCGATCATCAACAGCCCGATCAAACCGTTCAAGGCCACCGCATACCACAACGGCGACTTCGTGCAGGTGAGCGACGA
GACCCTGAAGGGCAAGTGGTCCGTCGTCGTGTTCTATCCCGCCGACTTCACGTTCGTGTGCCCGACCGAGCTCGGCGATC
TGGCCGAGCGCTACGCCGAATTCCAGAAGCTCGGCGTCGAAATCTACGCGGTGTCGACCGACACGCACTTCACGCACAAG
GCATGGCACGATACGTCGGACACGATCGCGAAGATCAAGTATCCGATGATCGGCGATCCGACGCTCGCGATCTCGCGCAA
CTTCGACGTGCTGATCGAAGAGGAAGGCCTCGCGCTGCGCGGCACGTTCGTGATCAATCCGCAGGGCGAGATCAAGCTGT
GCGAGATCCACGACAACGGCATCGGCCGCGACGCGGGCGAGTTGCTGCGCAAGGTCCAGGCCGCGCAATACGTCGCCGCG
CATCCGGGCGAAGTCTGCCCCGCCAAATGGACGCCGGGCGCCGACACGCTCACGCCGTCTCTCGACCTGATCGGCAAGAT
CTGA

Upstream 100 bases:

>100_bases
AATACCGATTCCGATCATTGAAACATGCAATTTCACAGAATCGGGCGTCATCGCCATACTGGCGCTTCCTGATCCAACAA
CGATTCAAGAGGAAGCGCAA

Downstream 100 bases:

>100_bases
AGCCACGCGGCGGGGCCGCCGCCGTTCGCGCCATGCGGGCCGAGGGTGCCGTGCGTTTCGTGGCCCGTTTGCGGCCCCCT
TGAGCCCGTTTTCAGCCGTT

Product: alkyl hydroperoxide reductase subunit C

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MPIINSPIKPFKATAYHNGDFVQVSDETLKGKWSVVVFYPADFTFVCPTELGDLAERYAEFQKLGVEIYAVSTDTHFTHK
AWHDTSDTIAKIKYPMIGDPTLAISRNFDVLIEEEGLALRGTFVINPQGEIKLCEIHDNGIGRDAGELLRKVQAAQYVAA
HPGEVCPAKWTPGADTLTPSLDLIGKI

Sequences:

>Translated_187_residues
MPIINSPIKPFKATAYHNGDFVQVSDETLKGKWSVVVFYPADFTFVCPTELGDLAERYAEFQKLGVEIYAVSTDTHFTHK
AWHDTSDTIAKIKYPMIGDPTLAISRNFDVLIEEEGLALRGTFVINPQGEIKLCEIHDNGIGRDAGELLRKVQAAQYVAA
HPGEVCPAKWTPGADTLTPSLDLIGKI
>Mature_186_residues
PIINSPIKPFKATAYHNGDFVQVSDETLKGKWSVVVFYPADFTFVCPTELGDLAERYAEFQKLGVEIYAVSTDTHFTHKA
WHDTSDTIAKIKYPMIGDPTLAISRNFDVLIEEEGLALRGTFVINPQGEIKLCEIHDNGIGRDAGELLRKVQAAQYVAAH
PGEVCPAKWTPGADTLTPSLDLIGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=173, Percent_Identity=46.8208092485549, Blast_Score=161, Evalue=4e-40,
Organism=Homo sapiens, GI5802974, Length=173, Percent_Identity=46.8208092485549, Blast_Score=160, Evalue=4e-40,
Organism=Homo sapiens, GI32189392, Length=182, Percent_Identity=43.956043956044, Blast_Score=158, Evalue=3e-39,
Organism=Homo sapiens, GI4505591, Length=182, Percent_Identity=41.2087912087912, Blast_Score=149, Evalue=1e-36,
Organism=Homo sapiens, GI32455266, Length=182, Percent_Identity=41.2087912087912, Blast_Score=149, Evalue=1e-36,
Organism=Homo sapiens, GI32455264, Length=182, Percent_Identity=41.2087912087912, Blast_Score=149, Evalue=1e-36,
Organism=Homo sapiens, GI5453549, Length=187, Percent_Identity=40.1069518716578, Blast_Score=143, Evalue=7e-35,
Organism=Homo sapiens, GI33188454, Length=81, Percent_Identity=49.3827160493827, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI4758638, Length=157, Percent_Identity=29.9363057324841, Blast_Score=67, Evalue=7e-12,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=66.8449197860963, Blast_Score=278, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI193204376, Length=182, Percent_Identity=43.4065934065934, Blast_Score=156, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI32565831, Length=182, Percent_Identity=43.4065934065934, Blast_Score=156, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17554494, Length=177, Percent_Identity=41.8079096045198, Blast_Score=147, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI25153706, Length=164, Percent_Identity=29.2682926829268, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323613, Length=175, Percent_Identity=40.5714285714286, Blast_Score=136, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6320661, Length=175, Percent_Identity=38.8571428571429, Blast_Score=136, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319407, Length=163, Percent_Identity=31.9018404907975, Blast_Score=88, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17738015, Length=184, Percent_Identity=40.7608695652174, Blast_Score=159, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24656348, Length=181, Percent_Identity=43.646408839779, Blast_Score=159, Evalue=1e-39,
Organism=Drosophila melanogaster, GI17864676, Length=181, Percent_Identity=43.646408839779, Blast_Score=159, Evalue=1e-39,
Organism=Drosophila melanogaster, GI21357347, Length=180, Percent_Identity=40.5555555555556, Blast_Score=151, Evalue=2e-37,
Organism=Drosophila melanogaster, GI17157991, Length=180, Percent_Identity=40.5555555555556, Blast_Score=148, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24641739, Length=180, Percent_Identity=40.5555555555556, Blast_Score=148, Evalue=2e-36,
Organism=Drosophila melanogaster, GI17975518, Length=158, Percent_Identity=31.6455696202532, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24652436, Length=158, Percent_Identity=31.6455696202532, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24652434, Length=158, Percent_Identity=31.6455696202532, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24581278, Length=158, Percent_Identity=31.6455696202532, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20619; Mature: 20487

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIINSPIKPFKATAYHNGDFVQVSDETLKGKWSVVVFYPADFTFVCPTELGDLAERYAE
CCCCCCCCCCCEEEEEECCCEEEECCCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHH
FQKLGVEIYAVSTDTHFTHKAWHDTSDTIAKIKYPMIGDPTLAISRNFDVLIEEEGLALR
HHHCCEEEEEEECCCCEEECCCCCCCCCEEEEECCCCCCCEEEEECCCEEEEECCCEEEE
GTFVINPQGEIKLCEIHDNGIGRDAGELLRKVQAAQYVAAHPGEVCPAKWTPGADTLTPS
EEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
LDLIGKI
HHHEECC
>Mature Secondary Structure 
PIINSPIKPFKATAYHNGDFVQVSDETLKGKWSVVVFYPADFTFVCPTELGDLAERYAE
CCCCCCCCCCEEEEEECCCEEEECCCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHH
FQKLGVEIYAVSTDTHFTHKAWHDTSDTIAKIKYPMIGDPTLAISRNFDVLIEEEGLALR
HHHCCEEEEEEECCCCEEECCCCCCCCCEEEEECCCCCCCEEEEECCCEEEEECCCEEEE
GTFVINPQGEIKLCEIHDNGIGRDAGELLRKVQAAQYVAAHPGEVCPAKWTPGADTLTPS
EEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
LDLIGKI
HHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]