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The map label for this gene is lolE [H]

Identifier: 126209490

GI number: 126209490

Start: 2263265

End: 2264515

Strand: Reverse

Name: lolE [H]

Synonym: APL_2036

Alternate gene names: 126209490

Gene position: 2264515-2263265 (Counterclockwise)

Preceding gene: 126209491

Following gene: 126209488

Centisome position: 99.56

GC content: 44.52

Gene sequence:

>1251_bases
ATGAATACCCCTTTTTTTATTAGCTGGCGTTATCAACGAGGCAAACAAAAAAATCGGTTGGTCTCCTTGATCTCACTATT
TTCCAGTGTCGGCATTGCGCTTGGTGTGGCAGTATTAATTATCGGCTTAAGTGCGATGAACGGTTTCGAACGAGAACTAA
ATCAGCGAGTGCTTTCCGTTGTTCCGCACGCTGAACTGTATTCCTACAACGGTAATGAAAACGCCCCGATACAAGCGGGC
AAAAAACTGGAAAATCTTGCAAATAGTAATCCGAATGTGACCGCTTCTTCGCCTTTCGTCAGCTTTACCGGCTTGATCGA
AAACGGTACGCAATTAAAAATCGCCCAAGTTCGAGGCGTTGATCCGGTTAAGCAAGATAAAGTCAGTTCGCTTAGCCATT
ATATTCCGAGTGAGCAATGGCAAGCGTTCCATCAACAAGGAGGCTTGATTCTTGGTGCCGGCATTGCTAAAGATTTGGAA
GTCGCCGCCGGCGATGAAGTCACACTGTTATTACCGCAGCCGACCGAAGACGGCAAATTGGCTCAACCGTTACGTTTCAG
CCTACCGGTAACCGGCGTACTAAAACTGGAAGGGCAACTCGACCATAGCTATGCGTTATTACCGATTGAAAAAGCCCAAG
AGCTATTGGAATATCAACCGAATGAATATTCGGGCATTGAGTTGGCATTAAAAGAGCCGTTTAAAGTACAAGAACTGCAA
ATGCCGGAACTCGCTAACTTTAATCAACCGCTGTATCTCAACACTTGGATTGAAAAATTCGGTTATATGTATAACGACAT
TCAGCTGGTTCGCACCGTGATGTATATTGCGATGGTGTTAGTGATTGGCGTAGCGTGTTTTAATATTATTTCTACGCTGA
TTATGGCGGTAAAAGATAAGCAGGGCGATATTGCGATTATGCGTACACTCGGTGCGAATAATGGGTTTATCAAACGTATT
TTTCTATGGTACGGCTTGCTGTCCGGTATGAAAGGGGCGTTGGCCGGGATTATACTCGGTGTGATATTGTCGCTGAATTT
AACCGCAATGATTAAAGCGATTGAAGGATTTTTCGGCATCAAATTGTTATCGGACGGTGTTTACTTCGTGGATTTCCTAC
CAAGTGAATTACATTGGCAAGATGTCGCTTATGTGTTAATCGCCACCATCGTATTAAGTCTATTCGCCAGCCTCTATCCG
GCAACCCGAGCGGCAAAATTAGAACCGGCGAAAGTGTTAAGCGGTCATTAA

Upstream 100 bases:

>100_bases
AAAATATCGCATTTTTGTTGGTCACTCACGACTTAAATCTGGCAAATAAATTAGCTCGCCGCTTTGTAATGCGAGACGGC
GTATTAAGCGAGGCGGATTA

Downstream 100 bases:

>100_bases
TTTGAAAATACTTTCAAACGATAATACGCAAAAACTCAGCTTTTCAGCTGAGTTTTTTATTTAACGGTTATTAATGCACA
TAACCGGCATCAATATCCGC

Product: outer membrane-specific lipoprotein transporter subunit LolE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MNTPFFISWRYQRGKQKNRLVSLISLFSSVGIALGVAVLIIGLSAMNGFERELNQRVLSVVPHAELYSYNGNENAPIQAG
KKLENLANSNPNVTASSPFVSFTGLIENGTQLKIAQVRGVDPVKQDKVSSLSHYIPSEQWQAFHQQGGLILGAGIAKDLE
VAAGDEVTLLLPQPTEDGKLAQPLRFSLPVTGVLKLEGQLDHSYALLPIEKAQELLEYQPNEYSGIELALKEPFKVQELQ
MPELANFNQPLYLNTWIEKFGYMYNDIQLVRTVMYIAMVLVIGVACFNIISTLIMAVKDKQGDIAIMRTLGANNGFIKRI
FLWYGLLSGMKGALAGIILGVILSLNLTAMIKAIEGFFGIKLLSDGVYFVDFLPSELHWQDVAYVLIATIVLSLFASLYP
ATRAAKLEPAKVLSGH

Sequences:

>Translated_416_residues
MNTPFFISWRYQRGKQKNRLVSLISLFSSVGIALGVAVLIIGLSAMNGFERELNQRVLSVVPHAELYSYNGNENAPIQAG
KKLENLANSNPNVTASSPFVSFTGLIENGTQLKIAQVRGVDPVKQDKVSSLSHYIPSEQWQAFHQQGGLILGAGIAKDLE
VAAGDEVTLLLPQPTEDGKLAQPLRFSLPVTGVLKLEGQLDHSYALLPIEKAQELLEYQPNEYSGIELALKEPFKVQELQ
MPELANFNQPLYLNTWIEKFGYMYNDIQLVRTVMYIAMVLVIGVACFNIISTLIMAVKDKQGDIAIMRTLGANNGFIKRI
FLWYGLLSGMKGALAGIILGVILSLNLTAMIKAIEGFFGIKLLSDGVYFVDFLPSELHWQDVAYVLIATIVLSLFASLYP
ATRAAKLEPAKVLSGH
>Mature_416_residues
MNTPFFISWRYQRGKQKNRLVSLISLFSSVGIALGVAVLIIGLSAMNGFERELNQRVLSVVPHAELYSYNGNENAPIQAG
KKLENLANSNPNVTASSPFVSFTGLIENGTQLKIAQVRGVDPVKQDKVSSLSHYIPSEQWQAFHQQGGLILGAGIAKDLE
VAAGDEVTLLLPQPTEDGKLAQPLRFSLPVTGVLKLEGQLDHSYALLPIEKAQELLEYQPNEYSGIELALKEPFKVQELQ
MPELANFNQPLYLNTWIEKFGYMYNDIQLVRTVMYIAMVLVIGVACFNIISTLIMAVKDKQGDIAIMRTLGANNGFIKRI
FLWYGLLSGMKGALAGIILGVILSLNLTAMIKAIEGFFGIKLLSDGVYFVDFLPSELHWQDVAYVLIATIVLSLFASLYP
ATRAAKLEPAKVLSGH

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=419, Percent_Identity=48.4486873508353, Blast_Score=391, Evalue=1e-110,
Organism=Escherichia coli, GI1787360, Length=413, Percent_Identity=27.8450363196126, Blast_Score=151, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925
- InterPro:   IPR011926 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45775; Mature: 45775

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPFFISWRYQRGKQKNRLVSLISLFSSVGIALGVAVLIIGLSAMNGFERELNQRVLSV
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VPHAELYSYNGNENAPIQAGKKLENLANSNPNVTASSPFVSFTGLIENGTQLKIAQVRGV
CCCHHHEECCCCCCCCCCCCHHHHHHHCCCCCEEECCCCEEEEHHHCCCCEEEEEEECCC
DPVKQDKVSSLSHYIPSEQWQAFHQQGGLILGAGIAKDLEVAAGDEVTLLLPQPTEDGKL
CCHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEEECCCCCCCCC
AQPLRFSLPVTGVLKLEGQLDHSYALLPIEKAQELLEYQPNEYSGIELALKEPFKVQELQ
CCCEEECCCCEEEEEECCCCCCCEEEEEHHHHHHHHHCCCCCCCCEEEEECCCCCHHHCC
MPELANFNQPLYLNTWIEKFGYMYNDIQLVRTVMYIAMVLVIGVACFNIISTLIMAVKDK
CCHHCCCCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGDIAIMRTLGANNGFIKRIFLWYGLLSGMKGALAGIILGVILSLNLTAMIKAIEGFFGI
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLLSDGVYFVDFLPSELHWQDVAYVLIATIVLSLFASLYPATRAAKLEPAKVLSGH
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCC
>Mature Secondary Structure
MNTPFFISWRYQRGKQKNRLVSLISLFSSVGIALGVAVLIIGLSAMNGFERELNQRVLSV
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VPHAELYSYNGNENAPIQAGKKLENLANSNPNVTASSPFVSFTGLIENGTQLKIAQVRGV
CCCHHHEECCCCCCCCCCCCHHHHHHHCCCCCEEECCCCEEEEHHHCCCCEEEEEEECCC
DPVKQDKVSSLSHYIPSEQWQAFHQQGGLILGAGIAKDLEVAAGDEVTLLLPQPTEDGKL
CCHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEEECCCCCCCCC
AQPLRFSLPVTGVLKLEGQLDHSYALLPIEKAQELLEYQPNEYSGIELALKEPFKVQELQ
CCCEEECCCCEEEEEECCCCCCCEEEEEHHHHHHHHHCCCCCCCCEEEEECCCCCHHHCC
MPELANFNQPLYLNTWIEKFGYMYNDIQLVRTVMYIAMVLVIGVACFNIISTLIMAVKDK
CCHHCCCCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGDIAIMRTLGANNGFIKRIFLWYGLLSGMKGALAGIILGVILSLNLTAMIKAIEGFFGI
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLLSDGVYFVDFLPSELHWQDVAYVLIATIVLSLFASLYPATRAAKLEPAKVLSGH
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]