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The map label for this gene is scrK [H]

Identifier: 126209488

GI number: 126209488

Start: 2261049

End: 2261972

Strand: Reverse

Name: scrK [H]

Synonym: APL_2034

Alternate gene names: 126209488

Gene position: 2261972-2261049 (Counterclockwise)

Preceding gene: 126209490

Following gene: 126209487

Centisome position: 99.45

GC content: 46.1

Gene sequence:

>924_bases
ATGGGCAAAATTTGGGTAACCGGCGATGCCGTAGTAGATTTAATTCCGGACGGCGAAAATCACTATTTGAAATGTGCGGG
CGGTGCGCCGGCAAACGTTGCGGTAGGTGTTTCACGTTTAGGCGTAGAGGCTGGTTTTATCGGTCGAGTCGGTTTAGATC
CGCTTGGCAAATTTATGCAGCAAACGCTTAATGCAGAAAAAGTTTCGACCGAACATATGATCCTCGATCCGAAACAACGT
ACTTCGACAGTGATCGTCGGTTTAGACGACGGTGAACGCAGTTTTACCTTTATGGTAAACCCGAGTGCGGATCAATTCCT
TGAAGCGGGCGATTTACCGACTTTCCAAAAAGGCGATTTCCTACATTGTTGTTCTATCGCATTAATTAACGATCCGTCAC
GTTCAACCACAATCGAAGCGATTCGCCGTATAAAAGCCGCCGGCGGTTTCTTCTCATTCGACCCGAATTTACGCGAATCG
CTTTGGGCAAGTCTTGAAGAAATGAAACAAGTGGTCAATAGCGTAGTGGCAATGGCGGACGTGCTTAAATTCTCTGAAGA
AGAATTAACCCTTTTAACCGATACCGCAACACTTGAACAAGCGACGAAAGCGATTACCGCTCAGTATCCGGAGAAATTAA
TCATTATCACGTTAGGTAAAGACGGTGCTATTTATCATTTAAACGGTCATAGCCAAACGGTTGCCGGTAAAGCGTTAAAA
CCGGTTGATACCACCGGTGCCGGCGATGCGTTTGTCAGCGGTTTACTTGCCGGTTTATCACAAGTTGAAAATTGGAAAGA
CGAAAGCGTATTGGTGGATGTTATTCGCAAAGCGAACGCTTCAGGCGCTTTAGCAACGACAGCAAAAGGTGCGATGTCGG
CATTACCGAATAAAGCCGAACTAGAAGCGTTTTTAGCGCAATAA

Upstream 100 bases:

>100_bases
CTAAATGTGACAAGCGGTAGGCTTGAAATAGCTTTTGCAAAACTAAACCGTTTTAGCTAAGATAAATTAACTATTTTTGA
CTAGATAAGAGAACACGATT

Downstream 100 bases:

>100_bases
TCACAACAAGCGGTGAAATTTCACCGCTTTTTTGCAATTTAGGATTTTATACTATGCAGATTTTCAATAACGGCAAATAC
AAAAGCCTTCACGCAGCAGA

Product: aminoimidazole riboside kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MGKIWVTGDAVVDLIPDGENHYLKCAGGAPANVAVGVSRLGVEAGFIGRVGLDPLGKFMQQTLNAEKVSTEHMILDPKQR
TSTVIVGLDDGERSFTFMVNPSADQFLEAGDLPTFQKGDFLHCCSIALINDPSRSTTIEAIRRIKAAGGFFSFDPNLRES
LWASLEEMKQVVNSVVAMADVLKFSEEELTLLTDTATLEQATKAITAQYPEKLIIITLGKDGAIYHLNGHSQTVAGKALK
PVDTTGAGDAFVSGLLAGLSQVENWKDESVLVDVIRKANASGALATTAKGAMSALPNKAELEAFLAQ

Sequences:

>Translated_307_residues
MGKIWVTGDAVVDLIPDGENHYLKCAGGAPANVAVGVSRLGVEAGFIGRVGLDPLGKFMQQTLNAEKVSTEHMILDPKQR
TSTVIVGLDDGERSFTFMVNPSADQFLEAGDLPTFQKGDFLHCCSIALINDPSRSTTIEAIRRIKAAGGFFSFDPNLRES
LWASLEEMKQVVNSVVAMADVLKFSEEELTLLTDTATLEQATKAITAQYPEKLIIITLGKDGAIYHLNGHSQTVAGKALK
PVDTTGAGDAFVSGLLAGLSQVENWKDESVLVDVIRKANASGALATTAKGAMSALPNKAELEAFLAQ
>Mature_306_residues
GKIWVTGDAVVDLIPDGENHYLKCAGGAPANVAVGVSRLGVEAGFIGRVGLDPLGKFMQQTLNAEKVSTEHMILDPKQRT
STVIVGLDDGERSFTFMVNPSADQFLEAGDLPTFQKGDFLHCCSIALINDPSRSTTIEAIRRIKAAGGFFSFDPNLRESL
WASLEEMKQVVNSVVAMADVLKFSEEELTLLTDTATLEQATKAITAQYPEKLIIITLGKDGAIYHLNGHSQTVAGKALKP
VDTTGAGDAFVSGLLAGLSQVENWKDESVLVDVIRKANASGALATTAKGAMSALPNKAELEAFLAQ

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87081971, Length=290, Percent_Identity=28.6206896551724, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082281, Length=276, Percent_Identity=26.0869565217391, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790193, Length=290, Percent_Identity=25.1724137931034, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082343, Length=289, Percent_Identity=26.2975778546713, Blast_Score=62, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20128807, Length=322, Percent_Identity=25.4658385093168, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.4 [H]

Molecular weight: Translated: 32667; Mature: 32535

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKIWVTGDAVVDLIPDGENHYLKCAGGAPANVAVGVSRLGVEAGFIGRVGLDPLGKFMQ
CCEEEEECCEEEEEECCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
QTLNAEKVSTEHMILDPKQRTSTVIVGLDDGERSFTFMVNPSADQFLEAGDLPTFQKGDF
HHCCHHHCCCCCEEECCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHCCCCCCCCCCCE
LHCCSIALINDPSRSTTIEAIRRIKAAGGFFSFDPNLRESLWASLEEMKQVVNSVVAMAD
EEEEEEEEECCCCCHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
VLKFSEEELTLLTDTATLEQATKAITAQYPEKLIIITLGKDGAIYHLNGHSQTVAGKALK
HHHCCCCCEEEEECHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCC
PVDTTGAGDAFVSGLLAGLSQVENWKDESVLVDVIRKANASGALATTAKGAMSALPNKAE
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHH
LEAFLAQ
HHHHHCC
>Mature Secondary Structure 
GKIWVTGDAVVDLIPDGENHYLKCAGGAPANVAVGVSRLGVEAGFIGRVGLDPLGKFMQ
CEEEEECCEEEEEECCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
QTLNAEKVSTEHMILDPKQRTSTVIVGLDDGERSFTFMVNPSADQFLEAGDLPTFQKGDF
HHCCHHHCCCCCEEECCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHCCCCCCCCCCCE
LHCCSIALINDPSRSTTIEAIRRIKAAGGFFSFDPNLRESLWASLEEMKQVVNSVVAMAD
EEEEEEEEECCCCCHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
VLKFSEEELTLLTDTATLEQATKAITAQYPEKLIIITLGKDGAIYHLNGHSQTVAGKALK
HHHCCCCCEEEEECHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCC
PVDTTGAGDAFVSGLLAGLSQVENWKDESVLVDVIRKANASGALATTAKGAMSALPNKAE
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHH
LEAFLAQ
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2174811 [H]