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The map label for this gene is hflX [H]

Identifier: 126209416

GI number: 126209416

Start: 2192241

End: 2193464

Strand: Direct

Name: hflX [H]

Synonym: APL_1962

Alternate gene names: 126209416

Gene position: 2192241-2193464 (Clockwise)

Preceding gene: 126209415

Following gene: 126209418

Centisome position: 96.38

GC content: 43.87

Gene sequence:

>1224_bases
ATGGAATTCCAAACGCTTGCCGAATCGGCCGGTGTTGAAATTCTTGCCACATTAACTACTTCTCGTTCCGCACCGCATAT
CAAATATTTTGTCGGACAAGGCAAAGCCGATGAAATCGCACAAGCGGTTAAAGATTTAGAAGCTACGGTTGTTTTAGTCA
ATCACGAGCTTAGTCCGTCACAAACCCGTAATTTACAAGCGTTATGCGAATGTCGAGTTGTGGACAGAACCGGTCTGATT
TTAGATATTTTTGCCCAACGTGCCAGATCGCACGAAGGAAAATTACAAGTCGAGCTGGCTCAACTTAAACACTTGGCAAC
ACGTTTGGTACGTCGTTTGGGCAATCAGGATCAGCAAAAGGGCGGGGCAGTAGGCTTACGAGGGCCGGGTGAAACTCAGC
TTGAAACTGATCGCCGTTTGATTAAAGTGCGCATTCAGCAACTTCAAAATCGTTTGGAGAAAGTGAATAAGCAGCGCAGC
CAAAATCGCAAAACTCGTCAGAAAGCGGATATTCCGACCGTTTCTTTGGTCGGTTATACCAATGCGGGGAAATCGACTTT
ATTCAATGCGATTACTAATGCCGGTGTTTATGCGGCGGATCAGTTATTCGCAACGCTTGATCCGACTTTACGCCGAATGC
AGATTCAAGATGTCGGCACTACAATCTTAGCGGATACGGTCGGTTTTATTCGTTTTTTACCGCATGATTTGGTCTCCGCA
TTTAAATCGACTTTACAAGAAACCACCGAAGCAAGCTTACTGTTACACGTGATTGATGCGGCGGATGATCGTAAAAATGA
AAATATTGACGCGGTCAATCAAGTCTTAGATGAAATCGGTGCGTTAGACATTCCAACGTTATTGGTCTATAACAAGGTTG
ATAAACTTGAAGGCATAGTGCCGCATATCGAGCGTAATGACGATGGTAAACCGGTGGCGGTTTATCTCTCCGCACAAGCT
AATCAAGGTATTGATTTGCTATATGAGGCGATTAGAGAATGTTTACGCAACGAGTTGGTGTGTGAGAAAGTATTATTACC
GGCAACCGCTGGGCAAATTTATACGCAACTTCACCTACAGCATTGTATTAAAAACGAAAGCTTTAATCAGTTTGGTGACC
GATTGGTTGAGGTGGAAGTGGATTTAGTGCAGTGGAATAAATGGCTAAAACAATTCCCCGAATTGACGGAATATATTGAA
TTCGCAAGTTGGGAAGAGAACTAG

Upstream 100 bases:

>100_bases
CGAGAATGGGAGAACCGCCGATAAAGAGCTATCCCATACGAAAGATAAAGCGATTTTAGTTCATCTCTTCCTTTCTCAAC
ATAAAGATATTGAGAATCTG

Downstream 100 bases:

>100_bases
CATACAGCGGGTAGCATTGCTACCGCCTTTTGCATTTAATAGCGGCGGATTTCCGGCGGTCTGTAATTTTGAATAAATTG
TTCGATTTCAGTGAAATCAT

Product: GTP-binding protein hflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MEFQTLAESAGVEILATLTTSRSAPHIKYFVGQGKADEIAQAVKDLEATVVLVNHELSPSQTRNLQALCECRVVDRTGLI
LDIFAQRARSHEGKLQVELAQLKHLATRLVRRLGNQDQQKGGAVGLRGPGETQLETDRRLIKVRIQQLQNRLEKVNKQRS
QNRKTRQKADIPTVSLVGYTNAGKSTLFNAITNAGVYAADQLFATLDPTLRRMQIQDVGTTILADTVGFIRFLPHDLVSA
FKSTLQETTEASLLLHVIDAADDRKNENIDAVNQVLDEIGALDIPTLLVYNKVDKLEGIVPHIERNDDGKPVAVYLSAQA
NQGIDLLYEAIRECLRNELVCEKVLLPATAGQIYTQLHLQHCIKNESFNQFGDRLVEVEVDLVQWNKWLKQFPELTEYIE
FASWEEN

Sequences:

>Translated_407_residues
MEFQTLAESAGVEILATLTTSRSAPHIKYFVGQGKADEIAQAVKDLEATVVLVNHELSPSQTRNLQALCECRVVDRTGLI
LDIFAQRARSHEGKLQVELAQLKHLATRLVRRLGNQDQQKGGAVGLRGPGETQLETDRRLIKVRIQQLQNRLEKVNKQRS
QNRKTRQKADIPTVSLVGYTNAGKSTLFNAITNAGVYAADQLFATLDPTLRRMQIQDVGTTILADTVGFIRFLPHDLVSA
FKSTLQETTEASLLLHVIDAADDRKNENIDAVNQVLDEIGALDIPTLLVYNKVDKLEGIVPHIERNDDGKPVAVYLSAQA
NQGIDLLYEAIRECLRNELVCEKVLLPATAGQIYTQLHLQHCIKNESFNQFGDRLVEVEVDLVQWNKWLKQFPELTEYIE
FASWEEN
>Mature_407_residues
MEFQTLAESAGVEILATLTTSRSAPHIKYFVGQGKADEIAQAVKDLEATVVLVNHELSPSQTRNLQALCECRVVDRTGLI
LDIFAQRARSHEGKLQVELAQLKHLATRLVRRLGNQDQQKGGAVGLRGPGETQLETDRRLIKVRIQQLQNRLEKVNKQRS
QNRKTRQKADIPTVSLVGYTNAGKSTLFNAITNAGVYAADQLFATLDPTLRRMQIQDVGTTILADTVGFIRFLPHDLVSA
FKSTLQETTEASLLLHVIDAADDRKNENIDAVNQVLDEIGALDIPTLLVYNKVDKLEGIVPHIERNDDGKPVAVYLSAQA
NQGIDLLYEAIRECLRNELVCEKVLLPATAGQIYTQLHLQHCIKNESFNQFGDRLVEVEVDLVQWNKWLKQFPELTEYIE
FASWEEN

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=235, Percent_Identity=32.3404255319149, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI310124267, Length=235, Percent_Identity=32.3404255319149, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI310124171, Length=235, Percent_Identity=32.3404255319149, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI310124169, Length=235, Percent_Identity=32.3404255319149, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI310133116, Length=241, Percent_Identity=31.5352697095436, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI310133118, Length=241, Percent_Identity=31.9502074688797, Blast_Score=105, Evalue=6e-23,
Organism=Escherichia coli, GI1790615, Length=398, Percent_Identity=62.5628140703518, Blast_Score=492, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17561038, Length=296, Percent_Identity=27.3648648648649, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24650079, Length=322, Percent_Identity=29.8136645962733, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 45640; Mature: 45640

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFQTLAESAGVEILATLTTSRSAPHIKYFVGQGKADEIAQAVKDLEATVVLVNHELSPS
CCHHHHHHHCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHEEEEEECCCCCC
QTRNLQALCECRVVDRTGLILDIFAQRARSHEGKLQVELAQLKHLATRLVRRLGNQDQQK
HHHCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHC
GGAVGLRGPGETQLETDRRLIKVRIQQLQNRLEKVNKQRSQNRKTRQKADIPTVSLVGYT
CCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
NAGKSTLFNAITNAGVYAADQLFATLDPTLRRMQIQDVGTTILADTVGFIRFLPHDLVSA
CCCHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKSTLQETTEASLLLHVIDAADDRKNENIDAVNQVLDEIGALDIPTLLVYNKVDKLEGIV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
PHIERNDDGKPVAVYLSAQANQGIDLLYEAIRECLRNELVCEKVLLPATAGQIYTQLHLQ
CCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
HCIKNESFNQFGDRLVEVEVDLVQWNKWLKQFPELTEYIEFASWEEN
HHHCCCCHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEFQTLAESAGVEILATLTTSRSAPHIKYFVGQGKADEIAQAVKDLEATVVLVNHELSPS
CCHHHHHHHCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHEEEEEECCCCCC
QTRNLQALCECRVVDRTGLILDIFAQRARSHEGKLQVELAQLKHLATRLVRRLGNQDQQK
HHHCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHC
GGAVGLRGPGETQLETDRRLIKVRIQQLQNRLEKVNKQRSQNRKTRQKADIPTVSLVGYT
CCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
NAGKSTLFNAITNAGVYAADQLFATLDPTLRRMQIQDVGTTILADTVGFIRFLPHDLVSA
CCCHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKSTLQETTEASLLLHVIDAADDRKNENIDAVNQVLDEIGALDIPTLLVYNKVDKLEGIV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
PHIERNDDGKPVAVYLSAQANQGIDLLYEAIRECLRNELVCEKVLLPATAGQIYTQLHLQ
CCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
HCIKNESFNQFGDRLVEVEVDLVQWNKWLKQFPELTEYIEFASWEEN
HHHCCCCHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]