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The map label for this gene is cysW [H]

Identifier: 126209309

GI number: 126209309

Start: 2077909

End: 2078721

Strand: Direct

Name: cysW [H]

Synonym: APL_1847

Alternate gene names: 126209309

Gene position: 2077909-2078721 (Clockwise)

Preceding gene: 126209308

Following gene: 126209310

Centisome position: 91.36

GC content: 43.79

Gene sequence:

>813_bases
ATGCAAAGTTTACTCAAAAAACGACCGCTTGTTGAAAGACTATTAATCGGCTTAGCGATTCTGCTATTTGTGATTTTGCT
ACTTTTACCGTTATTGGTGGTAATTTCACAAGGGTTGGCAAAAGGCTTGGATTTTTTCCTTGCGTCAATCAGCGAGGAAG
ATACGCTTGCTGCGCTAAAACTAACCTTATTAGCCGCAACAATTGCCGTGCCGCTGAATATCATTTTCGGCATTGCCGCA
GCTTGGGCGGTCGCGAAATATCAATTTAGAGGCAGACAGCTTTTGCTTACCTTAATTGATTTACCTTTTTCGATTTCACC
GGTGGTGGCAGGCTTAATTTACGTGTTGTTATTCGGCGCACAGAGTTGGCTTTATCCGCACTTACAAGCGGTCGATTTTC
AAATCGTTTATGCTATTCCGGGCATTATTTTAGCCACCCTATTTGTTTCTGTGCCTTTTGTCGCACGAGAACTGATTCCG
ATTATGGAAGCACAAGGCACAACGGAAGAAGAAGCGGCGGCGGTATTGGGCGCAAACGGCTGGCAAACTTTCTACCACGT
CACTTTACCGAATATCAAATGGGCGTTATTACACGGCGTGGTACTCTGTACCGCTCGTGCGTTAGGCGAATTCGGGGCGG
TTTCGGTAGTATCGGGACATATACGGGGATTAACTAACACCTTACCGCTGCAAATCGAAATTTTATACAACGAATACAAC
ATTGTAGCAGCATTTTCGGTCGCCATTTTATTACTCGGTTTATCTTTAATTTTATTATTTATTCGTCAGTGGACAGAGGC
GAAATTAGCATGA

Upstream 100 bases:

>100_bases
TGGTGCATTAATGTTGATCATCTCATTCGTACTGATTTTTGTGATCAACCTTATTCAGCGTTACTTCGCTAAGCGGACAG
CAAAATAGAAGGGAAGAAAT

Downstream 100 bases:

>100_bases
TAGTGGGGCATTATGGCAATTAGCGTTAAACAAATTAATAAGCGCTTTGGACAATTCCAAGCACTAAACAATATTGATTT
TAGTATTCAAAATGGTGAAC

Product: Sulfate transport system permease protein cysW

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MQSLLKKRPLVERLLIGLAILLFVILLLLPLLVVISQGLAKGLDFFLASISEEDTLAALKLTLLAATIAVPLNIIFGIAA
AWAVAKYQFRGRQLLLTLIDLPFSISPVVAGLIYVLLFGAQSWLYPHLQAVDFQIVYAIPGIILATLFVSVPFVARELIP
IMEAQGTTEEEAAAVLGANGWQTFYHVTLPNIKWALLHGVVLCTARALGEFGAVSVVSGHIRGLTNTLPLQIEILYNEYN
IVAAFSVAILLLGLSLILLFIRQWTEAKLA

Sequences:

>Translated_270_residues
MQSLLKKRPLVERLLIGLAILLFVILLLLPLLVVISQGLAKGLDFFLASISEEDTLAALKLTLLAATIAVPLNIIFGIAA
AWAVAKYQFRGRQLLLTLIDLPFSISPVVAGLIYVLLFGAQSWLYPHLQAVDFQIVYAIPGIILATLFVSVPFVARELIP
IMEAQGTTEEEAAAVLGANGWQTFYHVTLPNIKWALLHGVVLCTARALGEFGAVSVVSGHIRGLTNTLPLQIEILYNEYN
IVAAFSVAILLLGLSLILLFIRQWTEAKLA
>Mature_270_residues
MQSLLKKRPLVERLLIGLAILLFVILLLLPLLVVISQGLAKGLDFFLASISEEDTLAALKLTLLAATIAVPLNIIFGIAA
AWAVAKYQFRGRQLLLTLIDLPFSISPVVAGLIYVLLFGAQSWLYPHLQAVDFQIVYAIPGIILATLFVSVPFVARELIP
IMEAQGTTEEEAAAVLGANGWQTFYHVTLPNIKWALLHGVVLCTARALGEFGAVSVVSGHIRGLTNTLPLQIEILYNEYN
IVAAFSVAILLLGLSLILLFIRQWTEAKLA

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=253, Percent_Identity=52.5691699604743, Blast_Score=264, Evalue=5e-72,
Organism=Escherichia coli, GI1788764, Length=199, Percent_Identity=40.7035175879397, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1786980, Length=210, Percent_Identity=31.4285714285714, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29393; Mature: 29393

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSLLKKRPLVERLLIGLAILLFVILLLLPLLVVISQGLAKGLDFFLASISEEDTLAALK
CCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LTLLAATIAVPLNIIFGIAAAWAVAKYQFRGRQLLLTLIDLPFSISPVVAGLIYVLLFGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
QSWLYPHLQAVDFQIVYAIPGIILATLFVSVPFVARELIPIMEAQGTTEEEAAAVLGANG
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCC
WQTFYHVTLPNIKWALLHGVVLCTARALGEFGAVSVVSGHIRGLTNTLPLQIEILYNEYN
CCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEECCCH
IVAAFSVAILLLGLSLILLFIRQWTEAKLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQSLLKKRPLVERLLIGLAILLFVILLLLPLLVVISQGLAKGLDFFLASISEEDTLAALK
CCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LTLLAATIAVPLNIIFGIAAAWAVAKYQFRGRQLLLTLIDLPFSISPVVAGLIYVLLFGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
QSWLYPHLQAVDFQIVYAIPGIILATLFVSVPFVARELIPIMEAQGTTEEEAAAVLGANG
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCC
WQTFYHVTLPNIKWALLHGVVLCTARALGEFGAVSVVSGHIRGLTNTLPLQIEILYNEYN
CCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEECCCH
IVAAFSVAILLLGLSLILLFIRQWTEAKLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1708375 [H]