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The map label for this gene is ycfH [C]

Identifier: 126209274

GI number: 126209274

Start: 2031836

End: 2032624

Strand: Reverse

Name: ycfH [C]

Synonym: APL_1810

Alternate gene names: 126209274

Gene position: 2032624-2031836 (Counterclockwise)

Preceding gene: 126209276

Following gene: 126209273

Centisome position: 89.37

GC content: 41.95

Gene sequence:

>789_bases
TTGAAAGACTTATTTATTATCGACTCACATTGTCATTTAGATGCCTTAGATTACGAAACTCGCCATAAAAACGTGGACCA
GGTAATCGAAAATGCTAAAGCGCGTGGTGTACACCACTTTATTTCGATTTGTACCACGCTTGGGCGTTTTGAGGCGATGA
AAGCCTTAACTGCGCATCGTAATGATGTCTCGCTTTCTTGTGGCGTTCATCCGCTGAATATAGAAGAAGAGCCATTTGAT
TACGATAAATTACTTACCTTCGCACAAGATGAAAAAGTGGTTGCGATTGGCGAAACAGGATTAGATTATCACTACACGCC
GGAAACCAAAGCATTACAACAATCGCTGTTTTCACAACAAATTGACATTGCCAATAAAGTAAATAAACCGTTAATTATCC
ATACCCGTTCGGCTCGTCAAGATACGATGGATATGCTGATTGCCGGCAATGCTAAAAAATGCGGCGGCGTATTACACTGC
TTTACCGAAGATTGGAATATGGCAAAACGTGCGTTGGATATCGGTTTCTATATCTCGATTTCGGGGATTATCACATTCCG
CAATGCGGAAGAATTGCGTGATGTGGTACGTAAAGTGCCGCTCGATAGTTTATTGGTTGAGACCGATTCGCCTTATCTTG
CGCCGATTCCGTATCGTGGTAAACCGAATCAGCCGGCCTATGTGCGTGAAACTTGTGAATATCTTGCCGCACTAAAAGGC
GTTTCAACAGAAGAATTAGCTCGCATTACCACTGAAAATGTGCAAAACTTATTCAAGATTAAACTCTAA

Upstream 100 bases:

>100_bases
ATGCTACATTTGCCTTTTAGAGATAAATCTCTTTTCTATATATCTCTGAATATTCAAATCATTACATAATAGCTCGCAAA
TATTATATGTAGGAAAAACA

Downstream 100 bases:

>100_bases
TCTATCAAGTTAAAGGTTAAATAAAGGAACTCGAATGAAAGCGATTTTAAAATATTTTCTCATTCTCGTATCACTCTCAT
TTTTTATTGTGTTGGGCGGT

Product: putative Mg-dependent DNAse

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MKDLFIIDSHCHLDALDYETRHKNVDQVIENAKARGVHHFISICTTLGRFEAMKALTAHRNDVSLSCGVHPLNIEEEPFD
YDKLLTFAQDEKVVAIGETGLDYHYTPETKALQQSLFSQQIDIANKVNKPLIIHTRSARQDTMDMLIAGNAKKCGGVLHC
FTEDWNMAKRALDIGFYISISGIITFRNAEELRDVVRKVPLDSLLVETDSPYLAPIPYRGKPNQPAYVRETCEYLAALKG
VSTEELARITTENVQNLFKIKL

Sequences:

>Translated_262_residues
MKDLFIIDSHCHLDALDYETRHKNVDQVIENAKARGVHHFISICTTLGRFEAMKALTAHRNDVSLSCGVHPLNIEEEPFD
YDKLLTFAQDEKVVAIGETGLDYHYTPETKALQQSLFSQQIDIANKVNKPLIIHTRSARQDTMDMLIAGNAKKCGGVLHC
FTEDWNMAKRALDIGFYISISGIITFRNAEELRDVVRKVPLDSLLVETDSPYLAPIPYRGKPNQPAYVRETCEYLAALKG
VSTEELARITTENVQNLFKIKL
>Mature_262_residues
MKDLFIIDSHCHLDALDYETRHKNVDQVIENAKARGVHHFISICTTLGRFEAMKALTAHRNDVSLSCGVHPLNIEEEPFD
YDKLLTFAQDEKVVAIGETGLDYHYTPETKALQQSLFSQQIDIANKVNKPLIIHTRSARQDTMDMLIAGNAKKCGGVLHC
FTEDWNMAKRALDIGFYISISGIITFRNAEELRDVVRKVPLDSLLVETDSPYLAPIPYRGKPNQPAYVRETCEYLAALKG
VSTEELARITTENVQNLFKIKL

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=32.9588014981273, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI110349730, Length=267, Percent_Identity=32.9588014981273, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI226061853, Length=273, Percent_Identity=32.6007326007326, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI226061614, Length=258, Percent_Identity=31.7829457364341, Blast_Score=117, Evalue=8e-27,
Organism=Homo sapiens, GI226061595, Length=230, Percent_Identity=32.1739130434783, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI225903424, Length=219, Percent_Identity=26.9406392694064, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI225903439, Length=223, Percent_Identity=26.0089686098655, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI14042943, Length=225, Percent_Identity=25.7777777777778, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1787342, Length=257, Percent_Identity=57.9766536964981, Blast_Score=316, Evalue=9e-88,
Organism=Escherichia coli, GI87082439, Length=258, Percent_Identity=29.4573643410853, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI48994985, Length=246, Percent_Identity=31.7073170731707, Blast_Score=116, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17559024, Length=274, Percent_Identity=28.1021897810219, Blast_Score=120, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI71980746, Length=265, Percent_Identity=29.4339622641509, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17565396, Length=303, Percent_Identity=25.4125412541254, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17543026, Length=195, Percent_Identity=29.2307692307692, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24648690, Length=291, Percent_Identity=27.8350515463918, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24586117, Length=271, Percent_Identity=29.520295202952, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI221330018, Length=271, Percent_Identity=29.520295202952, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29622; Mature: 29622

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLFIIDSHCHLDALDYETRHKNVDQVIENAKARGVHHFISICTTLGRFEAMKALTAHR
CCCEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NDVSLSCGVHPLNIEEEPFDYDKLLTFAQDEKVVAIGETGLDYHYTPETKALQQSLFSQQ
CCCEEECCCEECCCCCCCCCHHHHHHHCCCCEEEEEECCCCCEEECCCHHHHHHHHHHHH
IDIANKVNKPLIIHTRSARQDTMDMLIAGNAKKCGGVLHCFTEDWNMAKRALDIGFYISI
HHHHHHCCCCEEEEECCCCHHHHHHEEECCCHHCCCEEEEECCCHHHHHHHHHEEEEEEE
SGIITFRNAEELRDVVRKVPLDSLLVETDSPYLAPIPYRGKPNQPAYVRETCEYLAALKG
EEEEEECCHHHHHHHHHHCCHHHEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCC
VSTEELARITTENVQNLFKIKL
CCHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MKDLFIIDSHCHLDALDYETRHKNVDQVIENAKARGVHHFISICTTLGRFEAMKALTAHR
CCCEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NDVSLSCGVHPLNIEEEPFDYDKLLTFAQDEKVVAIGETGLDYHYTPETKALQQSLFSQQ
CCCEEECCCEECCCCCCCCCHHHHHHHCCCCEEEEEECCCCCEEECCCHHHHHHHHHHHH
IDIANKVNKPLIIHTRSARQDTMDMLIAGNAKKCGGVLHCFTEDWNMAKRALDIGFYISI
HHHHHHCCCCEEEEECCCCHHHHHHEEECCCHHCCCEEEEECCCHHHHHHHHHEEEEEEE
SGIITFRNAEELRDVVRKVPLDSLLVETDSPYLAPIPYRGKPNQPAYVRETCEYLAALKG
EEEEEECCHHHHHHHHHHCCHHHEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCC
VSTEELARITTENVQNLFKIKL
CCHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]