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The map label for this gene is fucP [H]

Identifier: 126209152

GI number: 126209152

Start: 1918611

End: 1919900

Strand: Direct

Name: fucP [H]

Synonym: APL_1688

Alternate gene names: 126209152

Gene position: 1918611-1919900 (Clockwise)

Preceding gene: 126209151

Following gene: 126209153

Centisome position: 84.35

GC content: 44.34

Gene sequence:

>1290_bases
ATGACAGCTAAAGTTCTTGAGAAAAAATTTGTGGTGCCATTTATCCTGATCACCACGCTATTTGCCCTTTGGGGTTTTGC
AAATGATATTACCAACCCGATGGTAGCTGTATTCCAAACCGTAATGGAAATTCCGGCTTCCGAAGCCGCTCTGGTGCAGT
TCGCATTCTACGGCGGTTACGGTACTATGGCGATTCCCGCCGCATTGTTTGCCAGCCGCTACAGCTATAAAGCGGGGGTA
TTATTAGGTTTAGCATTATATGCCATTGGGGCGTTCCTCTTTATCCCGGCGGCAAAATATGAACAGTTCTCTTTCTTCCT
TTGGTCGCTTTATATTCTTACTTTCGGTTTAGCGTTCTTGGAAACTACGGCGAACCCGTTCATTCTTTCTATGGGTGATC
CGGCAACTGCGACCCGTCGTTTAAATTTAGCGCAATCTTTTAACCCGCTCGGTTCGATTACCGGTATGTTTGTCGCTTCA
CAAATCGTTTTAACCAACCTTGAATCGGAAAAACGTGATGCGGCGGGTAACTTATTGTTCAATACTTTATCGGAAGCGGA
AAAAGCGGTGATTAGAACCAACGACTTAGAAATGATTCGTAACCCGTATGTGGCGATTGGTATTGTGGTATTGGTGGTCT
TTATCATTATTGCGCTTTACAAAATGCCTGCAACCAAAATGGATGAACACGGTAAAATCTCTGTGAAAGAATCATTCGGT
CGTTTAATTAAAAATGCACGTTATCGTGAGGGTGTGATTGCACAAGTATTCTATGTTGGTGTGCAAATTATGTGTTGGAC
CTTCATTATCCAATATGCGGAACGTATTGGTTTAACTAAAGCGGAAGCGCAAAACTGGAATATTGCGGCAATGGCGCTCT
TTATCAGTAGCCGCTTTATCAGTACTGCTGTGATGAAATATCTTAAAGCGGAATTAATGTTGTTCCTGTTTGCGGTAGGA
GGTTTCTTCAGTATCTTAGGGGTAATGTTTATTGACGGTATGGGCGGCTTATATTGCCTTGTATTGACCTCCGGTTTTAT
GTCGCTTATGTTCCCGACTATTTATGGTATTGCGCTTGACGGACAATGCGAAGAATCGGCACTCGGTGCGGCTGGTTTAG
TGATGGCTATCGTGGGCGGAGCGTTAATGCCGCCGCTTCAAGGTTCGATTATCGATATGGGTACGGTTGCGGGTATGCCG
GCGGTAAACTTCTCATTTATCCTACCGTTAATTTGCTTCGTCGCTATCGCTATCTACGGTTTCCGCTGCTGGAAAGTGTT
AGTCAAATAG

Upstream 100 bases:

>100_bases
ATTGGAAAAATTCAAATCTTACGGTTCTTGGGTCGAAGAAAAATAAATGTAATCGAGAAATGTAATGACATCTTCATAAA
CAACGAAAAAGGAACGTCCT

Downstream 100 bases:

>100_bases
AGATAAAAGGAGCCATCAAGCGGTCGAGTTTTCCATAAAATTTGCAAGAAAATCGGAAAATAAGACCGCTTACCTTCCTT
ATCGGAAAATGAATTTTTAA

Product: L-fucose permease

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MTAKVLEKKFVVPFILITTLFALWGFANDITNPMVAVFQTVMEIPASEAALVQFAFYGGYGTMAIPAALFASRYSYKAGV
LLGLALYAIGAFLFIPAAKYEQFSFFLWSLYILTFGLAFLETTANPFILSMGDPATATRRLNLAQSFNPLGSITGMFVAS
QIVLTNLESEKRDAAGNLLFNTLSEAEKAVIRTNDLEMIRNPYVAIGIVVLVVFIIIALYKMPATKMDEHGKISVKESFG
RLIKNARYREGVIAQVFYVGVQIMCWTFIIQYAERIGLTKAEAQNWNIAAMALFISSRFISTAVMKYLKAELMLFLFAVG
GFFSILGVMFIDGMGGLYCLVLTSGFMSLMFPTIYGIALDGQCEESALGAAGLVMAIVGGALMPPLQGSIIDMGTVAGMP
AVNFSFILPLICFVAIAIYGFRCWKVLVK

Sequences:

>Translated_429_residues
MTAKVLEKKFVVPFILITTLFALWGFANDITNPMVAVFQTVMEIPASEAALVQFAFYGGYGTMAIPAALFASRYSYKAGV
LLGLALYAIGAFLFIPAAKYEQFSFFLWSLYILTFGLAFLETTANPFILSMGDPATATRRLNLAQSFNPLGSITGMFVAS
QIVLTNLESEKRDAAGNLLFNTLSEAEKAVIRTNDLEMIRNPYVAIGIVVLVVFIIIALYKMPATKMDEHGKISVKESFG
RLIKNARYREGVIAQVFYVGVQIMCWTFIIQYAERIGLTKAEAQNWNIAAMALFISSRFISTAVMKYLKAELMLFLFAVG
GFFSILGVMFIDGMGGLYCLVLTSGFMSLMFPTIYGIALDGQCEESALGAAGLVMAIVGGALMPPLQGSIIDMGTVAGMP
AVNFSFILPLICFVAIAIYGFRCWKVLVK
>Mature_428_residues
TAKVLEKKFVVPFILITTLFALWGFANDITNPMVAVFQTVMEIPASEAALVQFAFYGGYGTMAIPAALFASRYSYKAGVL
LGLALYAIGAFLFIPAAKYEQFSFFLWSLYILTFGLAFLETTANPFILSMGDPATATRRLNLAQSFNPLGSITGMFVASQ
IVLTNLESEKRDAAGNLLFNTLSEAEKAVIRTNDLEMIRNPYVAIGIVVLVVFIIIALYKMPATKMDEHGKISVKESFGR
LIKNARYREGVIAQVFYVGVQIMCWTFIIQYAERIGLTKAEAQNWNIAAMALFISSRFISTAVMKYLKAELMLFLFAVGG
FFSILGVMFIDGMGGLYCLVLTSGFMSLMFPTIYGIALDGQCEESALGAAGLVMAIVGGALMPPLQGSIIDMGTVAGMPA
VNFSFILPLICFVAIAIYGFRCWKVLVK

Specific function: Transport of L-fucose into the cell [H]

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family [H]

Homologues:

Organism=Escherichia coli, GI1789166, Length=422, Percent_Identity=33.4123222748815, Blast_Score=237, Evalue=8e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005275
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46878; Mature: 46747

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKVLEKKFVVPFILITTLFALWGFANDITNPMVAVFQTVMEIPASEAALVQFAFYGGY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
GTMAIPAALFASRYSYKAGVLLGLALYAIGAFLFIPAAKYEQFSFFLWSLYILTFGLAFL
CHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ETTANPFILSMGDPATATRRLNLAQSFNPLGSITGMFVASQIVLTNLESEKRDAAGNLLF
HHCCCCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
NTLSEAEKAVIRTNDLEMIRNPYVAIGIVVLVVFIIIALYKMPATKMDEHGKISVKESFG
HHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHH
RLIKNARYREGVIAQVFYVGVQIMCWTFIIQYAERIGLTKAEAQNWNIAAMALFISSRFI
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHH
STAVMKYLKAELMLFLFAVGGFFSILGVMFIDGMGGLYCLVLTSGFMSLMFPTIYGIALD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEC
GQCEESALGAAGLVMAIVGGALMPPLQGSIIDMGTVAGMPAVNFSFILPLICFVAIAIYG
CCCCHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHH
FRCWKVLVK
HHHHHHHCC
>Mature Secondary Structure 
TAKVLEKKFVVPFILITTLFALWGFANDITNPMVAVFQTVMEIPASEAALVQFAFYGGY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
GTMAIPAALFASRYSYKAGVLLGLALYAIGAFLFIPAAKYEQFSFFLWSLYILTFGLAFL
CHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ETTANPFILSMGDPATATRRLNLAQSFNPLGSITGMFVASQIVLTNLESEKRDAAGNLLF
HHCCCCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
NTLSEAEKAVIRTNDLEMIRNPYVAIGIVVLVVFIIIALYKMPATKMDEHGKISVKESFG
HHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHH
RLIKNARYREGVIAQVFYVGVQIMCWTFIIQYAERIGLTKAEAQNWNIAAMALFISSRFI
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHH
STAVMKYLKAELMLFLFAVGGFFSILGVMFIDGMGGLYCLVLTSGFMSLMFPTIYGIALD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEC
GQCEESALGAAGLVMAIVGGALMPPLQGSIIDMGTVAGMPAVNFSFILPLICFVAIAIYG
CCCCHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHH
FRCWKVLVK
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]