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The map label for this gene is rbsK [H]

Identifier: 126209137

GI number: 126209137

Start: 1898947

End: 1899858

Strand: Direct

Name: rbsK [H]

Synonym: APL_1673

Alternate gene names: 126209137

Gene position: 1898947-1899858 (Clockwise)

Preceding gene: 126209136

Following gene: 126209138

Centisome position: 83.49

GC content: 46.49

Gene sequence:

>912_bases
ATGAAAAAACTTTGTGTGTTGGGCAGCGTAAATGCGGATCATGTTATTCGAGTGCCTTATTTCCCGAAAGCGGGCGAAAC
GCTGAAAGGCGGTCATTATCACATTGCGTATGGCGGCAAAGGGGCTAATCAGGCAGTAGCGGCGGCTCGTGTGCGAAATA
CATCGTTAGTTGAGGTGGATTTTATCGCTTGTATCGGCGCTGATGATATTGGACGAGCGATGAAACAAGCCTTTGTGCAA
GACGGAATTAATCCCGAACACATTGTTGAAGTAGCTGACCAAATGACCGGCATTGCGATGATTCAAGTGGCGGATTCAGG
CGAGAATAGCATTGTAATTTCCGCCGGTGCAAATGCAAACTTAGATGAAAGCGTGGTGGCACAACATCAAGCTACGATTG
AAAGAGCGGATTGCTTACTGGTTCAGCTGGAAACGCCGTTACAAGCGGTCGAAAAAGCGTTAAAAATTGCTAAGGCAAAT
CATACTCAAGTCATTTTAAATCCGGCACCGGCACAACCGCTCTCAGATGAAATTTTGGCGAATATCGATATGATTACCCC
AAACGAAACGGAAACTGCCTTACTGACAGGCATTCAAGTGGTCGATGAACAAACCGCTCAACAAGCAGCGAATGTATTCC
ATCAAAAAGGGATTCAAACCGTGTTAATTACTTTGGGGGCGAAAGGGGCGTTTTTAAGTGAAAACGGTAACGGTGAAATA
ATTGCCGGCTTTAAAGTCACACCGGTGGACACCACCGCCGCCGGCGATACCTTTAACGGCGCATTGGCGATTGCTTTATT
AGAAGGCAAATCAATGCGAGATGCGGTCATGTTTGCCCACAAAGCCTCTTCGATTTCAGTCACTCGTATGGGGGCACAAA
GTTCTATTCCAACTCGAGCGGAATTAGTTTAA

Upstream 100 bases:

>100_bases
AGTGCCGTTAAAAGTGATTAGTCAGTAATTTTGGCTCCGGAACCGTTATTTTGACGGTTCCGGCATCGCTAGATTTGTTT
AAGGTCGGTTTGAGGTAGTT

Downstream 100 bases:

>100_bases
CTATTTTATTGAATCAATAAGCGGTTGGGTTTTTGCAGAAATTTGCAATAATTCGACCGCTTGTTTTTTTATTATTTCAC
CTTGTTATAAAAATCATTAT

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKKLCVLGSVNADHVIRVPYFPKAGETLKGGHYHIAYGGKGANQAVAAARVRNTSLVEVDFIACIGADDIGRAMKQAFVQ
DGINPEHIVEVADQMTGIAMIQVADSGENSIVISAGANANLDESVVAQHQATIERADCLLVQLETPLQAVEKALKIAKAN
HTQVILNPAPAQPLSDEILANIDMITPNETETALLTGIQVVDEQTAQQAANVFHQKGIQTVLITLGAKGAFLSENGNGEI
IAGFKVTPVDTTAAGDTFNGALAIALLEGKSMRDAVMFAHKASSISVTRMGAQSSIPTRAELV

Sequences:

>Translated_303_residues
MKKLCVLGSVNADHVIRVPYFPKAGETLKGGHYHIAYGGKGANQAVAAARVRNTSLVEVDFIACIGADDIGRAMKQAFVQ
DGINPEHIVEVADQMTGIAMIQVADSGENSIVISAGANANLDESVVAQHQATIERADCLLVQLETPLQAVEKALKIAKAN
HTQVILNPAPAQPLSDEILANIDMITPNETETALLTGIQVVDEQTAQQAANVFHQKGIQTVLITLGAKGAFLSENGNGEI
IAGFKVTPVDTTAAGDTFNGALAIALLEGKSMRDAVMFAHKASSISVTRMGAQSSIPTRAELV
>Mature_303_residues
MKKLCVLGSVNADHVIRVPYFPKAGETLKGGHYHIAYGGKGANQAVAAARVRNTSLVEVDFIACIGADDIGRAMKQAFVQ
DGINPEHIVEVADQMTGIAMIQVADSGENSIVISAGANANLDESVVAQHQATIERADCLLVQLETPLQAVEKALKIAKAN
HTQVILNPAPAQPLSDEILANIDMITPNETETALLTGIQVVDEQTAQQAANVFHQKGIQTVLITLGAKGAFLSENGNGEI
IAGFKVTPVDTTAAGDTFNGALAIALLEGKSMRDAVMFAHKASSISVTRMGAQSSIPTRAELV

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=303, Percent_Identity=37.6237623762376, Blast_Score=152, Evalue=4e-37,
Organism=Escherichia coli, GI1790193, Length=299, Percent_Identity=52.5083612040134, Blast_Score=283, Evalue=8e-78,
Organism=Escherichia coli, GI87081971, Length=303, Percent_Identity=25.7425742574257, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87082343, Length=243, Percent_Identity=26.7489711934156, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788491, Length=255, Percent_Identity=23.921568627451, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788484, Length=308, Percent_Identity=24.6753246753247, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=304, Percent_Identity=34.5394736842105, Blast_Score=158, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6319884, Length=332, Percent_Identity=28.3132530120482, Blast_Score=116, Evalue=3e-27,
Organism=Drosophila melanogaster, GI20128807, Length=307, Percent_Identity=37.4592833876222, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24583886, Length=308, Percent_Identity=29.5454545454545, Blast_Score=115, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31799; Mature: 31799

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLCVLGSVNADHVIRVPYFPKAGETLKGGHYHIAYGGKGANQAVAAARVRNTSLVEVD
CCCEEEEECCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCEEEEEE
FIACIGADDIGRAMKQAFVQDGINPEHIVEVADQMTGIAMIQVADSGENSIVISAGANAN
EEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEEECCCCCEEEEECCCCCC
LDESVVAQHQATIERADCLLVQLETPLQAVEKALKIAKANHTQVILNPAPAQPLSDEILA
CCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHH
NIDMITPNETETALLTGIQVVDEQTAQQAANVFHQKGIQTVLITLGAKGAFLSENGNGEI
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCE
IAGFKVTPVDTTAAGDTFNGALAIALLEGKSMRDAVMFAHKASSISVTRMGAQSSIPTRA
EEEEEECCCCCCCCCCCCCCEEEEEEECCCCHHHHHHEEECCCCEEEEECCCCCCCCCHH
ELV
CCC
>Mature Secondary Structure
MKKLCVLGSVNADHVIRVPYFPKAGETLKGGHYHIAYGGKGANQAVAAARVRNTSLVEVD
CCCEEEEECCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCEEEEEE
FIACIGADDIGRAMKQAFVQDGINPEHIVEVADQMTGIAMIQVADSGENSIVISAGANAN
EEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEEECCCCCEEEEECCCCCC
LDESVVAQHQATIERADCLLVQLETPLQAVEKALKIAKANHTQVILNPAPAQPLSDEILA
CCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHH
NIDMITPNETETALLTGIQVVDEQTAQQAANVFHQKGIQTVLITLGAKGAFLSENGNGEI
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCE
IAGFKVTPVDTTAAGDTFNGALAIALLEGKSMRDAVMFAHKASSISVTRMGAQSSIPTRA
EEEEEECCCCCCCCCCCCCCEEEEEEECCCCHHHHHHEEECCCCEEEEECCCCCCCCCHH
ELV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]