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The map label for this gene is oxyR [H]

Identifier: 126208945

GI number: 126208945

Start: 1695891

End: 1696784

Strand: Reverse

Name: oxyR [H]

Synonym: APL_1481

Alternate gene names: 126208945

Gene position: 1696784-1695891 (Counterclockwise)

Preceding gene: 126208948

Following gene: 126208944

Centisome position: 74.6

GC content: 43.18

Gene sequence:

>894_bases
GTGAATATTAGAGATTTAGAATATTTAATCGCTTTAGCAGACTATAAACATTTCCGCCGAGCGGCGGACGCCTGTAACGT
CAGCCAGCCGACACTAAGCGGTCAAATTCGCAAACTAGAGGACGAATTAGGTACGGTATTACTTGAACGTACCAGCCGTA
AGGTATTATTTACCCAAGCCGGTTTAACTCTTGTCGAACAAGCGAAAGCCGTCTTACGTGAAGTAAAAGTGCTAAAAGAG
ATGGCAAGTAACCAAGGGAAAGAAATGTCCGGACCGCTGCATGTCGGCATTATTCCGACCCTTGGTCCGTACCTTTTACC
ACTTGTATTGCCGGCATTGAAATCGACATTCCCCGAGTTGGAACTCTATATTTATGAGCTGCAAACCACGCAACTGGTTG
ATCAACTTGAATCCGGACAACTGGATTGCGGAATTTTAGCTTTTGTCAAAGAAAGCGAACCCTTTATCGAAGTGCCTATT
TTTAACGAACAAATGCTTTTAGCGGTTTCAGATAAACATGAGTGGTCGCATAAAAGTAAGATGGATATTTCATACTTAAA
AGATAAAGAATTACTCTTTTTAGACGACGGGCATTGCCTACGTACGCAAACGCTTGATTATTGCTTATCCGTCGGTGCCA
AAGAAAGCACGCACTTTAAAGCGACCAATCTTGAAACGTTACGTAATATGGTGGCGGCGAACGTCGGGATGTCACTTATT
CCGGAATTAGCGGCGAAGCCTTGCGAGGGACTGAATTACCTCACATTTGATGAACCTAAACCTTATCGCACCGTCGGCTT
AATTTATCGTCCGGGTTCACCGCTACGTATTCGTTACGAACGTCTTGCAAAAGAAGTTTCCAAGATTATGAAACAAGAGA
AAATTCATGAGTAA

Upstream 100 bases:

>100_bases
TTTTTCAAAAACCGCACGCATTCTACACCTAAATATGCCATAATTCATCCTATTTAATTAATAGGAAAACAGTCATCCTT
TGATCTCATGAGGAGTAGTT

Downstream 100 bases:

>100_bases
TATCGGTATCCGCGCCCAACAAAAAGAGAAAACGCGTCGTGCATTGGTGGATGCGGCTTTTAACCAATTAAGTGCGGAAA
AAAGTTTTTCTAACTTGAGT

Product: DNA-binding transcriptional regulator OxyR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNIRDLEYLIALADYKHFRRAADACNVSQPTLSGQIRKLEDELGTVLLERTSRKVLFTQAGLTLVEQAKAVLREVKVLKE
MASNQGKEMSGPLHVGIIPTLGPYLLPLVLPALKSTFPELELYIYELQTTQLVDQLESGQLDCGILAFVKESEPFIEVPI
FNEQMLLAVSDKHEWSHKSKMDISYLKDKELLFLDDGHCLRTQTLDYCLSVGAKESTHFKATNLETLRNMVAANVGMSLI
PELAAKPCEGLNYLTFDEPKPYRTVGLIYRPGSPLRIRYERLAKEVSKIMKQEKIHE

Sequences:

>Translated_297_residues
MNIRDLEYLIALADYKHFRRAADACNVSQPTLSGQIRKLEDELGTVLLERTSRKVLFTQAGLTLVEQAKAVLREVKVLKE
MASNQGKEMSGPLHVGIIPTLGPYLLPLVLPALKSTFPELELYIYELQTTQLVDQLESGQLDCGILAFVKESEPFIEVPI
FNEQMLLAVSDKHEWSHKSKMDISYLKDKELLFLDDGHCLRTQTLDYCLSVGAKESTHFKATNLETLRNMVAANVGMSLI
PELAAKPCEGLNYLTFDEPKPYRTVGLIYRPGSPLRIRYERLAKEVSKIMKQEKIHE
>Mature_297_residues
MNIRDLEYLIALADYKHFRRAADACNVSQPTLSGQIRKLEDELGTVLLERTSRKVLFTQAGLTLVEQAKAVLREVKVLKE
MASNQGKEMSGPLHVGIIPTLGPYLLPLVLPALKSTFPELELYIYELQTTQLVDQLESGQLDCGILAFVKESEPFIEVPI
FNEQMLLAVSDKHEWSHKSKMDISYLKDKELLFLDDGHCLRTQTLDYCLSVGAKESTHFKATNLETLRNMVAANVGMSLI
PELAAKPCEGLNYLTFDEPKPYRTVGLIYRPGSPLRIRYERLAKEVSKIMKQEKIHE

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=293, Percent_Identity=64.1638225255973, Blast_Score=397, Evalue=1e-112,
Organism=Escherichia coli, GI157672245, Length=271, Percent_Identity=28.4132841328413, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1788887, Length=243, Percent_Identity=29.2181069958848, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788297, Length=266, Percent_Identity=28.5714285714286, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787879, Length=247, Percent_Identity=27.5303643724696, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI145693105, Length=282, Percent_Identity=24.822695035461, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787530, Length=252, Percent_Identity=24.6031746031746, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI2367136, Length=272, Percent_Identity=25.7352941176471, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790208, Length=314, Percent_Identity=24.8407643312102, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788748, Length=258, Percent_Identity=24.8062015503876, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788296, Length=261, Percent_Identity=25.2873563218391, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787601, Length=145, Percent_Identity=26.8965517241379, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI145693193, Length=144, Percent_Identity=34.7222222222222, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33624; Mature: 33624

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRDLEYLIALADYKHFRRAADACNVSQPTLSGQIRKLEDELGTVLLERTSRKVLFTQA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEHH
GLTLVEQAKAVLREVKVLKEMASNQGKEMSGPLHVGIIPTLGPYLLPLVLPALKSTFPEL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCE
ELYIYELQTTQLVDQLESGQLDCGILAFVKESEPFIEVPIFNEQMLLAVSDKHEWSHKSK
EEEEEEHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCEEEEEECCCCCCCCCCC
MDISYLKDKELLFLDDGHCLRTQTLDYCLSVGAKESTHFKATNLETLRNMVAANVGMSLI
CCHHHCCCCCEEEEECCCEEHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHCCHHHH
PELAAKPCEGLNYLTFDEPKPYRTVGLIYRPGSPLRIRYERLAKEVSKIMKQEKIHE
HHHHCCCCCCCCCEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIRDLEYLIALADYKHFRRAADACNVSQPTLSGQIRKLEDELGTVLLERTSRKVLFTQA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEHH
GLTLVEQAKAVLREVKVLKEMASNQGKEMSGPLHVGIIPTLGPYLLPLVLPALKSTFPEL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCE
ELYIYELQTTQLVDQLESGQLDCGILAFVKESEPFIEVPIFNEQMLLAVSDKHEWSHKSK
EEEEEEHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCEEEEEECCCCCCCCCCC
MDISYLKDKELLFLDDGHCLRTQTLDYCLSVGAKESTHFKATNLETLRNMVAANVGMSLI
CCHHHCCCCCEEEEECCCEEHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHCCHHHH
PELAAKPCEGLNYLTFDEPKPYRTVGLIYRPGSPLRIRYERLAKEVSKIMKQEKIHE
HHHHCCCCCCCCCEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 8890216 [H]