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The map label for this gene is oxaA [H]

Identifier: 126208888

GI number: 126208888

Start: 1629241

End: 1630722

Strand: Direct

Name: oxaA [H]

Synonym: APL_1424

Alternate gene names: 126208888

Gene position: 1629241-1630722 (Clockwise)

Preceding gene: 126208887

Following gene: 126208896

Centisome position: 71.63

GC content: 43.39

Gene sequence:

>1482_bases
GTGCTTGCGGCATCTAACGCAAATACCGTTATTGCGGAGAATGCAACCCAAGGTAAAACCGTCACGCTTGAAAGTGATGT
ATTACGTTTAACCATCGACACTTTAGGTGGCGATGTAATTGCTTCGGATTTATTAGCGCATAATGCGGAATTAAATTCCC
AAACGCCATTCAAATTATTACAAACCGGAGCGACGACTTATGTTGCGCAAAGCGGTTTAGTCGGCAAAAACGGGATCGAT
ACCAATGCAGGTCGTCCGCAATACCAAGTTGCACAAGATACGTTCGTTTTGGCGGAAGGTCAAAATGAAATGAGCGTACC
GATGACGTTTGAAAAAGACGGTGTGCTTTATACCAAAACCTTTGTGTTAAAACGCGGTAGCTATGATGTTGCGGTGAACT
TCAATGTGAAAAACCAAACGGCGGCAACCGTCGAAGTTCAGCCTTACGGTCAAATCAAACATACCTTATTGGAAAGTTCA
GGCAGCTTAACTATGCCGACTTATACCGGCGGTGCGTATTCTTCAGCCGAAACAAACTATAAAAAATATAGTTTCCAAGA
TATGGAGAAAGCTAACCTCGATATTAATACGAAAGCGGGTTGGGTTGCGTTATTACAACACTATTTCGTTTCCGCTTGGG
TACCGAATCAAGATGCGGAAAATACGATTTACTCTCGTACCAACAACGGCATTGCGACCATCGGTTATCGTGGTCCGGTA
ACAACTATCGCACCGAATAGCGAAGCGACGATTACCAGCCAATTATGGACCGGTCCGAAAGACCAAAAAGAAATGGAAGC
GACCGCAGCAAACCTTGATTTAACCGTAGATTACGGTTGGGCGTGGTTTATTGCGAAACCGTTATTTGCGTTACTGACTT
TCATCCAAAGCATCGTGACAAACTGGGGTTTAGCGATTATCGGGGTTACCATTGTGGTTAAAACCATTCTTTACCCATTA
ACCAAAGCGCAATATACCTCAATGGCAAGAATGCGTATGCTACAACCGAAAATCCAAGAAATGCGCGAGCGTTTCGGCGA
TGATCGTCAGCGTATGAGCCAAGAGATGATGAAGCTCTATAAAGAAGAAAAAGTAAACCCGATGGGCGGCTGTTTACCGA
TTCTTATCCAAATGCCGATTTTCATCGCATTATATTGGACCTTTATGGAAGCGGTGGAACTTCGTCACGCACCGTTCTTC
GGTTGGATTCAAGACTTATCCGCACAAGACCCGTACTACATTCTTCCGTTATTAATGGGTGCGTCGATGTTCTTGTTACA
GAAAATGTCGCCTAGTCCGGTAACCGATCCGGTACAACAAAAAGTAATGACCTTTATGCCGGTAATGTTTACCGTATTCT
TCTTATGGTTCCCGTCAGGCTTAGTACTTTACTGGCTGACTTCAAACATCATTACGATTGTTCAACAATGGTTAATCTAT
CGTAATCTTGAGAAGAAAGGCTTACATTCTCGTAAAAAATAA

Upstream 100 bases:

>100_bases
TTTCTTGATTTTTACGCAATGGCAACAGGATTTTAATCCTGAAATTTAAGCGCAAAAACAAGCACAACAACAAGCTCAAG
TTGCATCACAATCAGGCGAT

Downstream 100 bases:

>100_bases
ACGAGATAATATTTAAAATATCCGCACGCCGAATCGGAATTATTCCTTTTAGCGTGCGGATTTTTTATGCCTTTAAGTCG
GTAGCAAATAGTCTATAAGA

Product: putative inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MLAASNANTVIAENATQGKTVTLESDVLRLTIDTLGGDVIASDLLAHNAELNSQTPFKLLQTGATTYVAQSGLVGKNGID
TNAGRPQYQVAQDTFVLAEGQNEMSVPMTFEKDGVLYTKTFVLKRGSYDVAVNFNVKNQTAATVEVQPYGQIKHTLLESS
GSLTMPTYTGGAYSSAETNYKKYSFQDMEKANLDINTKAGWVALLQHYFVSAWVPNQDAENTIYSRTNNGIATIGYRGPV
TTIAPNSEATITSQLWTGPKDQKEMEATAANLDLTVDYGWAWFIAKPLFALLTFIQSIVTNWGLAIIGVTIVVKTILYPL
TKAQYTSMARMRMLQPKIQEMRERFGDDRQRMSQEMMKLYKEEKVNPMGGCLPILIQMPIFIALYWTFMEAVELRHAPFF
GWIQDLSAQDPYYILPLLMGASMFLLQKMSPSPVTDPVQQKVMTFMPVMFTVFFLWFPSGLVLYWLTSNIITIVQQWLIY
RNLEKKGLHSRKK

Sequences:

>Translated_493_residues
MLAASNANTVIAENATQGKTVTLESDVLRLTIDTLGGDVIASDLLAHNAELNSQTPFKLLQTGATTYVAQSGLVGKNGID
TNAGRPQYQVAQDTFVLAEGQNEMSVPMTFEKDGVLYTKTFVLKRGSYDVAVNFNVKNQTAATVEVQPYGQIKHTLLESS
GSLTMPTYTGGAYSSAETNYKKYSFQDMEKANLDINTKAGWVALLQHYFVSAWVPNQDAENTIYSRTNNGIATIGYRGPV
TTIAPNSEATITSQLWTGPKDQKEMEATAANLDLTVDYGWAWFIAKPLFALLTFIQSIVTNWGLAIIGVTIVVKTILYPL
TKAQYTSMARMRMLQPKIQEMRERFGDDRQRMSQEMMKLYKEEKVNPMGGCLPILIQMPIFIALYWTFMEAVELRHAPFF
GWIQDLSAQDPYYILPLLMGASMFLLQKMSPSPVTDPVQQKVMTFMPVMFTVFFLWFPSGLVLYWLTSNIITIVQQWLIY
RNLEKKGLHSRKK
>Mature_493_residues
MLAASNANTVIAENATQGKTVTLESDVLRLTIDTLGGDVIASDLLAHNAELNSQTPFKLLQTGATTYVAQSGLVGKNGID
TNAGRPQYQVAQDTFVLAEGQNEMSVPMTFEKDGVLYTKTFVLKRGSYDVAVNFNVKNQTAATVEVQPYGQIKHTLLESS
GSLTMPTYTGGAYSSAETNYKKYSFQDMEKANLDINTKAGWVALLQHYFVSAWVPNQDAENTIYSRTNNGIATIGYRGPV
TTIAPNSEATITSQLWTGPKDQKEMEATAANLDLTVDYGWAWFIAKPLFALLTFIQSIVTNWGLAIIGVTIVVKTILYPL
TKAQYTSMARMRMLQPKIQEMRERFGDDRQRMSQEMMKLYKEEKVNPMGGCLPILIQMPIFIALYWTFMEAVELRHAPFF
GWIQDLSAQDPYYILPLLMGASMFLLQKMSPSPVTDPVQQKVMTFMPVMFTVFFLWFPSGLVLYWLTSNIITIVQQWLIY
RNLEKKGLHSRKK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI223718097, Length=193, Percent_Identity=27.4611398963731, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1790140, Length=489, Percent_Identity=57.8732106339468, Blast_Score=585, Evalue=1e-168,
Organism=Drosophila melanogaster, GI24662345, Length=194, Percent_Identity=31.9587628865979, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21356443, Length=194, Percent_Identity=31.9587628865979, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 55290; Mature: 55290

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAASNANTVIAENATQGKTVTLESDVLRLTIDTLGGDVIASDLLAHNAELNSQTPFKLL
CCCCCCCCEEEEECCCCCCEEEEECCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHH
QTGATTYVAQSGLVGKNGIDTNAGRPQYQVAQDTFVLAEGQNEMSVPMTFEKDGVLYTKT
HCCCHHHHHCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCCCCEEECCCCEEEEEE
FVLKRGSYDVAVNFNVKNQTAATVEVQPYGQIKHTLLESSGSLTMPTYTGGAYSSAETNY
EEEECCCEEEEEEEEECCCEEEEEEECCCHHHHHHHHHCCCCEECCEECCCCCCCCCCCC
KKYSFQDMEKANLDINTKAGWVALLQHYFVSAWVPNQDAENTIYSRTNNGIATIGYRGPV
CCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHEECCCCEEEEECCCCE
TTIAPNSEATITSQLWTGPKDQKEMEATAANLDLTVDYGWAWFIAKPLFALLTFIQSIVT
EEECCCCCCEEEHHHCCCCCCHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
NWGLAIIGVTIVVKTILYPLTKAQYTSMARMRMLQPKIQEMRERFGDDRQRMSQEMMKLY
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
KEEKVNPMGGCLPILIQMPIFIALYWTFMEAVELRHAPFFGWIQDLSAQDPYYILPLLMG
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEHHHHHHH
ASMFLLQKMSPSPVTDPVQQKVMTFMPVMFTVFFLWFPSGLVLYWLTSNIITIVQQWLIY
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHH
RNLEKKGLHSRKK
HCHHHHCCCCCCC
>Mature Secondary Structure
MLAASNANTVIAENATQGKTVTLESDVLRLTIDTLGGDVIASDLLAHNAELNSQTPFKLL
CCCCCCCCEEEEECCCCCCEEEEECCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHH
QTGATTYVAQSGLVGKNGIDTNAGRPQYQVAQDTFVLAEGQNEMSVPMTFEKDGVLYTKT
HCCCHHHHHCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCCCCEEECCCCEEEEEE
FVLKRGSYDVAVNFNVKNQTAATVEVQPYGQIKHTLLESSGSLTMPTYTGGAYSSAETNY
EEEECCCEEEEEEEEECCCEEEEEEECCCHHHHHHHHHCCCCEECCEECCCCCCCCCCCC
KKYSFQDMEKANLDINTKAGWVALLQHYFVSAWVPNQDAENTIYSRTNNGIATIGYRGPV
CCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHEECCCCEEEEECCCCE
TTIAPNSEATITSQLWTGPKDQKEMEATAANLDLTVDYGWAWFIAKPLFALLTFIQSIVT
EEECCCCCCEEEHHHCCCCCCHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
NWGLAIIGVTIVVKTILYPLTKAQYTSMARMRMLQPKIQEMRERFGDDRQRMSQEMMKLY
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
KEEKVNPMGGCLPILIQMPIFIALYWTFMEAVELRHAPFFGWIQDLSAQDPYYILPLLMG
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEHHHHHHH
ASMFLLQKMSPSPVTDPVQQKVMTFMPVMFTVFFLWFPSGLVLYWLTSNIITIVQQWLIY
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHH
RNLEKKGLHSRKK
HCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA