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The map label for this gene is ccmB [H]

Identifier: 126208835

GI number: 126208835

Start: 1568191

End: 1568853

Strand: Reverse

Name: ccmB [H]

Synonym: APL_1371

Alternate gene names: 126208835

Gene position: 1568853-1568191 (Counterclockwise)

Preceding gene: 126208836

Following gene: 126208834

Centisome position: 68.98

GC content: 43.89

Gene sequence:

>663_bases
ATGATTTTATTTACTATTATTCAACGCGAATTAACCATCGCTTTGCGTAAGCCGGCGGAAATATTGAACCCGCTTTGGTT
CTTTCTGATTGTGATTACTTTGTTCCCGCTTCTTATGGGACCAAATCCCGAATTATTAGGGAAAATCGCACCGGGCGTCG
CTTGGGTAGCGGCATTACTTTCCGCTTTATTATCGTTTGAAAGACTTTTTCGTGACGACTATTTAGACGGCTCGCTTGAG
CAATTAATGTTATTGCCTATCGGTTTACCGCAGGTCGCATTAGCGAAAGTGATTGCGCATTGGTTACTAACGGGACTTCC
GCTAATTCTGCTTTCGCCGGTTGCGGCAATCTTACTTTCGTTAGAAACAAATGTATGGTGGGCATTGGTGCTAACCTTAT
TACTTGGTACGCCGATTTTAAGTTGTTTAGGTGCGATTGGCGTCGCTTTAACGGTCGGTTTGCGTAAAGGCGGAACTTTA
CTAAGTTTACTTATTCTACCGTTATTTTTACCGGTGCTGATTTTTGCCGCAGCCGTATTAGAAGCGGCGACATTGAATAT
GGGATATAGTGGGCAGCTTGCGATTATCGGGGCGATATTGGCTTTGACGCTGACTTTCTCACCTTTTGCAATAGCAGGCG
CATTAAGAATAAGCCTTCAGTAA

Upstream 100 bases:

>100_bases
TTGAAAAGCATTGCGAAAATGGCGGAATGGTTATTTTTACCAGTCATCAAGCGGCGGAAAGTCATAAAGTTAAAATCTTA
TCTTTGGATCAGTTTAAACT

Downstream 100 bases:

>100_bases
GTAATGAAAAGCGGTGAGATTTTTAATCTTTTTTGTAATTTGGAGATGTTATGTGGAAATGGCTTCATCCCTATGCTAAA
TCGGAAACACAATATCGATT

Product: heme exporter protein B

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MILFTIIQRELTIALRKPAEILNPLWFFLIVITLFPLLMGPNPELLGKIAPGVAWVAALLSALLSFERLFRDDYLDGSLE
QLMLLPIGLPQVALAKVIAHWLLTGLPLILLSPVAAILLSLETNVWWALVLTLLLGTPILSCLGAIGVALTVGLRKGGTL
LSLLILPLFLPVLIFAAAVLEAATLNMGYSGQLAIIGAILALTLTFSPFAIAGALRISLQ

Sequences:

>Translated_220_residues
MILFTIIQRELTIALRKPAEILNPLWFFLIVITLFPLLMGPNPELLGKIAPGVAWVAALLSALLSFERLFRDDYLDGSLE
QLMLLPIGLPQVALAKVIAHWLLTGLPLILLSPVAAILLSLETNVWWALVLTLLLGTPILSCLGAIGVALTVGLRKGGTL
LSLLILPLFLPVLIFAAAVLEAATLNMGYSGQLAIIGAILALTLTFSPFAIAGALRISLQ
>Mature_220_residues
MILFTIIQRELTIALRKPAEILNPLWFFLIVITLFPLLMGPNPELLGKIAPGVAWVAALLSALLSFERLFRDDYLDGSLE
QLMLLPIGLPQVALAKVIAHWLLTGLPLILLSPVAAILLSLETNVWWALVLTLLLGTPILSCLGAIGVALTVGLRKGGTL
LSLLILPLFLPVLIFAAAVLEAATLNMGYSGQLAIIGAILALTLTFSPFAIAGALRISLQ

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=220, Percent_Identity=63.6363636363636, Blast_Score=217, Evalue=6e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 23529; Mature: 23529

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILFTIIQRELTIALRKPAEILNPLWFFLIVITLFPLLMGPNPELLGKIAPGVAWVAALL
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHH
SALLSFERLFRDDYLDGSLEQLMLLPIGLPQVALAKVIAHWLLTGLPLILLSPVAAILLS
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LETNVWWALVLTLLLGTPILSCLGAIGVALTVGLRKGGTLLSLLILPLFLPVLIFAAAVL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
EAATLNMGYSGQLAIIGAILALTLTFSPFAIAGALRISLQ
HHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHEECC
>Mature Secondary Structure
MILFTIIQRELTIALRKPAEILNPLWFFLIVITLFPLLMGPNPELLGKIAPGVAWVAALL
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHH
SALLSFERLFRDDYLDGSLEQLMLLPIGLPQVALAKVIAHWLLTGLPLILLSPVAAILLS
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LETNVWWALVLTLLLGTPILSCLGAIGVALTVGLRKGGTLLSLLILPLFLPVLIFAAAVL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
EAATLNMGYSGQLAIIGAILALTLTFSPFAIAGALRISLQ
HHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]