Click here to switch to the map view.

The map label for this gene is galE [H]

Identifier: 126208767

GI number: 126208767

Start: 1491032

End: 1492048

Strand: Reverse

Name: galE [H]

Synonym: APL_1301

Alternate gene names: 126208767

Gene position: 1492048-1491032 (Counterclockwise)

Preceding gene: 126208768

Following gene: 126208766

Centisome position: 65.6

GC content: 38.74

Gene sequence:

>1017_bases
ATGGCTATTTTAGTAACTGGTGGTGCAGGTTATATCGGCACACATACGATTGTTGAATTATTAAATATTAATCGAGAAGT
GGTTGTATTGGATAATTTACATAATTCATCTGAAGTTTCGCTTGAACGTGTAAAACAAATTACCGGTAAAGCGGTGAAAT
TTTATAAAGGTGATGTATTAGATCGTGAAATTTTACGCAAAATTTTTGCCGAACATAAAATTGAATCGGTTATTCACTTT
GCCGGTTTAAAAGCTGTCGGTGAGAGCGTACAAAAACCGCTTTTCTATTATGAAAATAATGTAGGCGGTTCTATTGTTTT
AGTGGAAGAAATGATTAAAGCGGGCGTCAATACGATTGTATTTAGTTCTACGGCAACCGTTTATGGTGTGCCTGAAGTAG
TACCTGTTACCGAAGCTTGCCGTGTGGGCGATACAACCAGCCCTTATGCAACCTCTAAATATATGGTTGAACGAGTATTA
GCGGATACGGTAAAAGCAAATCCTCAATTTAGTGCGGTAATTTTACGTTATTTTAATCCGGTTGGTGCGCATGAAAGCGG
TTTAATCGGTGAAGATCCTAACGGTATCCCAAATAATCTTATGCCGTTTATCAGCCAAGTGGCTGTAGGTAAATTACCAC
AACTTTCAGTATTTGGCGGTGACTACGAAACGCATGATGGTACCGGTGTTCGTGATTATATTCATGTGGTCGATTTAGCC
ATCGGGCATTTAAAAGCATTAGATAAACATCAAGATGATGCCGGCTTGCATATCTATAACTTAGGTACGGGTATCGGTTA
TTCGGTATTGGATATGGTAACAGCATTTGAAAAAGCCAATGACATTAAAGTACCTTACCAAATTGTCGCTCGTCGTGCCG
GAGACATTGATTCATACTATTCAAATCCGCAAAAAGCACTTGATGAGTTAGGCTGGAAAACCGAACGCGGTTTAGAACAA
ATGATGAAAGACACTTGGAATTGGCAAAAAAATAACCCGAACGGTTATAAAGGCTAA

Upstream 100 bases:

>100_bases
CGAACAAGAATTTATCGCTTTAACCGGCGAAAATTAAATTATCGTTTGTCAGCAAAAAAGCGTAAAATACAAGCGGTCGA
ATTTCTAAGAGGATTTACAA

Downstream 100 bases:

>100_bases
CAAGCATTAATTAAACGAAGGCACAAGCGTTTAGGTTTGTGCCTTTTTTATCTCCGAAAATTTCTGTTATGATGTTTGAT
AATTAAGCTAATACAAAGTT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MAILVTGGAGYIGTHTIVELLNINREVVVLDNLHNSSEVSLERVKQITGKAVKFYKGDVLDREILRKIFAEHKIESVIHF
AGLKAVGESVQKPLFYYENNVGGSIVLVEEMIKAGVNTIVFSSTATVYGVPEVVPVTEACRVGDTTSPYATSKYMVERVL
ADTVKANPQFSAVILRYFNPVGAHESGLIGEDPNGIPNNLMPFISQVAVGKLPQLSVFGGDYETHDGTGVRDYIHVVDLA
IGHLKALDKHQDDAGLHIYNLGTGIGYSVLDMVTAFEKANDIKVPYQIVARRAGDIDSYYSNPQKALDELGWKTERGLEQ
MMKDTWNWQKNNPNGYKG

Sequences:

>Translated_338_residues
MAILVTGGAGYIGTHTIVELLNINREVVVLDNLHNSSEVSLERVKQITGKAVKFYKGDVLDREILRKIFAEHKIESVIHF
AGLKAVGESVQKPLFYYENNVGGSIVLVEEMIKAGVNTIVFSSTATVYGVPEVVPVTEACRVGDTTSPYATSKYMVERVL
ADTVKANPQFSAVILRYFNPVGAHESGLIGEDPNGIPNNLMPFISQVAVGKLPQLSVFGGDYETHDGTGVRDYIHVVDLA
IGHLKALDKHQDDAGLHIYNLGTGIGYSVLDMVTAFEKANDIKVPYQIVARRAGDIDSYYSNPQKALDELGWKTERGLEQ
MMKDTWNWQKNNPNGYKG
>Mature_337_residues
AILVTGGAGYIGTHTIVELLNINREVVVLDNLHNSSEVSLERVKQITGKAVKFYKGDVLDREILRKIFAEHKIESVIHFA
GLKAVGESVQKPLFYYENNVGGSIVLVEEMIKAGVNTIVFSSTATVYGVPEVVPVTEACRVGDTTSPYATSKYMVERVLA
DTVKANPQFSAVILRYFNPVGAHESGLIGEDPNGIPNNLMPFISQVAVGKLPQLSVFGGDYETHDGTGVRDYIHVVDLAI
GHLKALDKHQDDAGLHIYNLGTGIGYSVLDMVTAFEKANDIKVPYQIVARRAGDIDSYYSNPQKALDELGWKTERGLEQM
MKDTWNWQKNNPNGYKG

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=55.8823529411765, Blast_Score=400, Evalue=1e-111,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=55.8823529411765, Blast_Score=400, Evalue=1e-111,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=55.8823529411765, Blast_Score=400, Evalue=1e-111,
Organism=Homo sapiens, GI7657641, Length=346, Percent_Identity=26.878612716763, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=53.2738095238095, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI1788353, Length=367, Percent_Identity=27.2479564032698, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI48994969, Length=369, Percent_Identity=26.2872628726287, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=53.6231884057971, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=53.314121037464, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17568069, Length=339, Percent_Identity=24.188790560472, Blast_Score=74, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=50.2906976744186, Blast_Score=344, Evalue=1e-95,
Organism=Drosophila melanogaster, GI19923002, Length=342, Percent_Identity=57.3099415204678, Blast_Score=407, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37145; Mature: 37014

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILVTGGAGYIGTHTIVELLNINREVVVLDNLHNSSEVSLERVKQITGKAVKFYKGDVL
CEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHH
DREILRKIFAEHKIESVIHFAGLKAVGESVQKPLFYYENNVGGSIVLVEEMIKAGVNTIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEHHHHHHCCCCEEE
FSSTATVYGVPEVVPVTEACRVGDTTSPYATSKYMVERVLADTVKANPQFSAVILRYFNP
EECCCEEECCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
VGAHESGLIGEDPNGIPNNLMPFISQVAVGKLPQLSVFGGDYETHDGTGVRDYIHVVDLA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHH
IGHLKALDKHQDDAGLHIYNLGTGIGYSVLDMVTAFEKANDIKVPYQIVARRAGDIDSYY
HHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHH
SNPQKALDELGWKTERGLEQMMKDTWNWQKNNPNGYKG
CCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
AILVTGGAGYIGTHTIVELLNINREVVVLDNLHNSSEVSLERVKQITGKAVKFYKGDVL
EEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHH
DREILRKIFAEHKIESVIHFAGLKAVGESVQKPLFYYENNVGGSIVLVEEMIKAGVNTIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEHHHHHHCCCCEEE
FSSTATVYGVPEVVPVTEACRVGDTTSPYATSKYMVERVLADTVKANPQFSAVILRYFNP
EECCCEEECCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
VGAHESGLIGEDPNGIPNNLMPFISQVAVGKLPQLSVFGGDYETHDGTGVRDYIHVVDLA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHH
IGHLKALDKHQDDAGLHIYNLGTGIGYSVLDMVTAFEKANDIKVPYQIVARRAGDIDSYY
HHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHH
SNPQKALDELGWKTERGLEQMMKDTWNWQKNNPNGYKG
CCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8641792 [H]