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The map label for this gene is malF [H]

Identifier: 126208704

GI number: 126208704

Start: 1423046

End: 1424596

Strand: Direct

Name: malF [H]

Synonym: APL_1238

Alternate gene names: 126208704

Gene position: 1423046-1424596 (Clockwise)

Preceding gene: 126208703

Following gene: 126208705

Centisome position: 62.57

GC content: 38.36

Gene sequence:

>1551_bases
ATGCCAACATCAAATACAATGCCCCCTTCTCAACTTTGGGCTAAACGTCTATTTATCGGATTACTCTATCTGCTTTCTTT
CTACCTCGTGTTCACCATTTATCTACAAGGCGAAATTCTCTTTGCCTTACTTGTTTTAGTTGTTGTGACCACAGGGATCT
ATATTTTTTCAAATCAATCAACTTATCGTTGGCGCTATGTTTACCCTGGCGTTTCTGCTATGGGGATTTTTGTGTTATTC
CCGTTAATCTGCACTGTCGTTATCGCCTTTACAAATTATAGCGGATCCAATCAACTTAACTTTAAACAAGTCGTCCGCCA
ATTACAAAATCAGACTTACGCAGCAGGCGATCATCTGAATTTTAAATTGCTGCAAACTAATGAAAATCAGTATCAACTTG
CATTAAGTAACCCTAATTCGCAAAAAAATTATCTTTCTGAACCGCTTGTATTGGATGCCCTCCCTGCTGAATTAGCTGTA
ACTGAAGTAGAGCAGCTCCCTAACATCTCGGTTGCCCCTTTAAAAACAATTACGCAAAACCGAACTAAATTACAAGCAAT
AAAAGTATTATTACCAAGCGAACAAATCGTTACGATGAGTTCTCTCCGCCAATTTGCTGAACAAAAAACACGCTATACAT
TTGATGAACAAAATCAGATCTTAACGAATAATGAGAGTGGTGAACGCTATAAACCGAATGATGATATCGGCTTTTTCCAA
CCTATTGACGAACAAGGTAATTTTACAGGCAATCGACTAGAACCAGGTTATACCGTTTCAGTAGGTTGGCAAAATTTCGT
CAAAATCTTAACTGATGATGGTGTTCAAGAACCATTCATTAAAATCTTTATTTGGACTGTCGTATTTGCCCTTTTAACTG
TGATTTTTACAACTTTACTCGGTATGATTTTTGCTTCGCTCGTACAATGGGAAGCATTAAAAGGTAAAGCGGTCTATCGT
CTGTTATTAATTTTACCTTACGCCGTACCCGGCTTTATTTCGATTTTAGTCTTCAAAGGTTTATTTAACCAAAGTTTCGG
TGAAATCAACCTCATTCTGAACCAATTATTCGGTATCCGTCCGGAATGGTTTAATGATCCGTTCTTAGCCAAAGCAATGT
TACTGATTGTGAATACTTGGTTAGGCTACCCGTATATGATGATTGTTTGCATGGGCTTGCTAAAAGCGATTCCACACGAT
TTATATGAAGCTTCTGCGATTGATGGCGCAAGCGTATGGCAAAATTTCACGAAAATTACCATGCCATTGCTAGTTAAACC
ACTTATGCCGTTAATGATTGCCAGCTTCGCTTTTAACTTTAATAACTTTGTATTAATTCAGTTATTAACTAACGGCGGCC
CAAATATGGTAGGCACAACAACACCGGCTGGTCATACCGATTTACTGGTCAGTTACACTTATCGTATTGCCTTTGAAGGT
AGCGGTACACAAGACTTTGGTTTAGCGGCTGCAATCGCCGTCATCATCTTCTTGCTAGTAAGCGGATTAGCATTATTCCA
AATCAGAATGACGAAATTATCACAAGACTAA

Upstream 100 bases:

>100_bases
GGCCAAAATTGAAAAAGAATAACTTTTGCTAACCTCACTGTTAGGACGCCTATTAGAGGCGTCCTATACCTCCAGCTTAT
CAATTTACAGGGGAAACACT

Downstream 100 bases:

>100_bases
TTGACATTGTTCCTTCTACATACGAAGAAGGAGCAAAGAGGATATCAACTATGGCTATTGTTCAACCTAAATCAATGAAA
TTGCGTTTATTTTCCACGCA

Product: maltose transporter membrane protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MPTSNTMPPSQLWAKRLFIGLLYLLSFYLVFTIYLQGEILFALLVLVVVTTGIYIFSNQSTYRWRYVYPGVSAMGIFVLF
PLICTVVIAFTNYSGSNQLNFKQVVRQLQNQTYAAGDHLNFKLLQTNENQYQLALSNPNSQKNYLSEPLVLDALPAELAV
TEVEQLPNISVAPLKTITQNRTKLQAIKVLLPSEQIVTMSSLRQFAEQKTRYTFDEQNQILTNNESGERYKPNDDIGFFQ
PIDEQGNFTGNRLEPGYTVSVGWQNFVKILTDDGVQEPFIKIFIWTVVFALLTVIFTTLLGMIFASLVQWEALKGKAVYR
LLLILPYAVPGFISILVFKGLFNQSFGEINLILNQLFGIRPEWFNDPFLAKAMLLIVNTWLGYPYMMIVCMGLLKAIPHD
LYEASAIDGASVWQNFTKITMPLLVKPLMPLMIASFAFNFNNFVLIQLLTNGGPNMVGTTTPAGHTDLLVSYTYRIAFEG
SGTQDFGLAAAIAVIIFLLVSGLALFQIRMTKLSQD

Sequences:

>Translated_516_residues
MPTSNTMPPSQLWAKRLFIGLLYLLSFYLVFTIYLQGEILFALLVLVVVTTGIYIFSNQSTYRWRYVYPGVSAMGIFVLF
PLICTVVIAFTNYSGSNQLNFKQVVRQLQNQTYAAGDHLNFKLLQTNENQYQLALSNPNSQKNYLSEPLVLDALPAELAV
TEVEQLPNISVAPLKTITQNRTKLQAIKVLLPSEQIVTMSSLRQFAEQKTRYTFDEQNQILTNNESGERYKPNDDIGFFQ
PIDEQGNFTGNRLEPGYTVSVGWQNFVKILTDDGVQEPFIKIFIWTVVFALLTVIFTTLLGMIFASLVQWEALKGKAVYR
LLLILPYAVPGFISILVFKGLFNQSFGEINLILNQLFGIRPEWFNDPFLAKAMLLIVNTWLGYPYMMIVCMGLLKAIPHD
LYEASAIDGASVWQNFTKITMPLLVKPLMPLMIASFAFNFNNFVLIQLLTNGGPNMVGTTTPAGHTDLLVSYTYRIAFEG
SGTQDFGLAAAIAVIIFLLVSGLALFQIRMTKLSQD
>Mature_515_residues
PTSNTMPPSQLWAKRLFIGLLYLLSFYLVFTIYLQGEILFALLVLVVVTTGIYIFSNQSTYRWRYVYPGVSAMGIFVLFP
LICTVVIAFTNYSGSNQLNFKQVVRQLQNQTYAAGDHLNFKLLQTNENQYQLALSNPNSQKNYLSEPLVLDALPAELAVT
EVEQLPNISVAPLKTITQNRTKLQAIKVLLPSEQIVTMSSLRQFAEQKTRYTFDEQNQILTNNESGERYKPNDDIGFFQP
IDEQGNFTGNRLEPGYTVSVGWQNFVKILTDDGVQEPFIKIFIWTVVFALLTVIFTTLLGMIFASLVQWEALKGKAVYRL
LLILPYAVPGFISILVFKGLFNQSFGEINLILNQLFGIRPEWFNDPFLAKAMLLIVNTWLGYPYMMIVCMGLLKAIPHDL
YEASAIDGASVWQNFTKITMPLLVKPLMPLMIASFAFNFNNFVLIQLLTNGGPNMVGTTTPAGHTDLLVSYTYRIAFEGS
GTQDFGLAAAIAVIIFLLVSGLALFQIRMTKLSQD

Specific function: Part of the binding-protein-dependent transport system for maltose; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Periplasmic side. Note=A substantial portion of it protrudes into the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790465, Length=484, Percent_Identity=60.1239669421488, Blast_Score=607, Evalue=1e-175,
Organism=Escherichia coli, GI1787570, Length=260, Percent_Identity=28.8461538461538, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789861, Length=283, Percent_Identity=29.3286219081272, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 58075; Mature: 57944

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTSNTMPPSQLWAKRLFIGLLYLLSFYLVFTIYLQGEILFALLVLVVVTTGIYIFSNQS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
TYRWRYVYPGVSAMGIFVLFPLICTVVIAFTNYSGSNQLNFKQVVRQLQNQTYAAGDHLN
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEECCCCCE
FKLLQTNENQYQLALSNPNSQKNYLSEPLVLDALPAELAVTEVEQLPNISVAPLKTITQN
EEEEECCCCEEEEEECCCCCCHHHCCCCCEEECCCHHHHHHHHHHCCCCCCCCHHHHHCC
RTKLQAIKVLLPSEQIVTMSSLRQFAEQKTRYTFDEQNQILTNNESGERYKPNDDIGFFQ
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCC
PIDEQGNFTGNRLEPGYTVSVGWQNFVKILTDDGVQEPFIKIFIWTVVFALLTVIFTTLL
CCCCCCCCCCCCCCCCEEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GMIFASLVQWEALKGKAVYRLLLILPYAVPGFISILVFKGLFNQSFGEINLILNQLFGIR
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
PEWFNDPFLAKAMLLIVNTWLGYPYMMIVCMGLLKAIPHDLYEASAIDGASVWQNFTKIT
CCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHH
MPLLVKPLMPLMIASFAFNFNNFVLIQLLTNGGPNMVGTTTPAGHTDLLVSYTYRIAFEG
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEEEC
SGTQDFGLAAAIAVIIFLLVSGLALFQIRMTKLSQD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PTSNTMPPSQLWAKRLFIGLLYLLSFYLVFTIYLQGEILFALLVLVVVTTGIYIFSNQS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
TYRWRYVYPGVSAMGIFVLFPLICTVVIAFTNYSGSNQLNFKQVVRQLQNQTYAAGDHLN
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEECCCCCE
FKLLQTNENQYQLALSNPNSQKNYLSEPLVLDALPAELAVTEVEQLPNISVAPLKTITQN
EEEEECCCCEEEEEECCCCCCHHHCCCCCEEECCCHHHHHHHHHHCCCCCCCCHHHHHCC
RTKLQAIKVLLPSEQIVTMSSLRQFAEQKTRYTFDEQNQILTNNESGERYKPNDDIGFFQ
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCC
PIDEQGNFTGNRLEPGYTVSVGWQNFVKILTDDGVQEPFIKIFIWTVVFALLTVIFTTLL
CCCCCCCCCCCCCCCCEEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GMIFASLVQWEALKGKAVYRLLLILPYAVPGFISILVFKGLFNQSFGEINLILNQLFGIR
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
PEWFNDPFLAKAMLLIVNTWLGYPYMMIVCMGLLKAIPHDLYEASAIDGASVWQNFTKIT
CCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHH
MPLLVKPLMPLMIASFAFNFNNFVLIQLLTNGGPNMVGTTTPAGHTDLLVSYTYRIAFEG
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEEEC
SGTQDFGLAAAIAVIIFLLVSGLALFQIRMTKLSQD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2674653 [H]