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The map label for this gene is nahR [H]

Identifier: 126208658

GI number: 126208658

Start: 1368533

End: 1369432

Strand: Reverse

Name: nahR [H]

Synonym: APL_1190

Alternate gene names: 126208658

Gene position: 1369432-1368533 (Counterclockwise)

Preceding gene: 126208661

Following gene: 126208656

Centisome position: 60.21

GC content: 45.33

Gene sequence:

>900_bases
ATGCGTGATATTAGAACCGTTGATTTAAACTTATTGAAAGCGTTTGATGCACTCTTGCAAGAACGTAACGTAACCAAAGC
GGCACAACGTTTGTCGGTGACTCAGCCGGCAATGAGTGCGATGCTAAATCGTCTGCGTGATAGCTTTGGCGATCCGTTAT
TTGTGCGTGTGCAACACGGGATTGAACCGACCGCCAGAGCCTTGGCATTAATGCCTTCGGTCAAGACCATTTTGGCGGAA
GTGAATCGTATGCTGCGTCCGGTGGAGTTTGATCCGCAAACGGCTGAAATGACGATTAAGATTGCTTCTACCGATTATGG
CTTGGAAGCGATCGGTACACCTTTTTTATCCCATTTAAAGCAACTTGCACCGAAAATTCGTGTCGCTTTTTTACCGGCAC
AAGACGTGGATTTGTTAGCCCAATTTGAACAGGCAAGAATTGATATTGCCTTGGTTTCCACCCAACATATTCCGGCGGAT
TTACACAGCAAACCGTTGCTGACAGAACATTATGTTTGTGTGATGCGAGCAGATCACCCAATGGCAAACCAACTGTTAAA
TTTAGACAACTTTTGTGAATTGGATTTTGCAATGATGTCTTATGACGGCGGACAATTTTACGGCGTATGTGATGAAGCTC
TGGCTAAATTAGGCAAAACTCGCCGTGTGTCGGTCTCGGTCAATCACTTCTCACTGTTACCAAATATCTTGCGTACGACG
GATGTAGTAGCGCTGATTCCGTCACGGTTATCTCATCATCTCACAGGGCTGATTTGCAAAACGCTTCCGCTTGAAGTGCA
AGGTTTCTCATTGCAAATGGCGTGGCACGAACGTACTCACCAAGACCCAGCTTATCAATGGATCAGAAATTTGTTGGTGG
AGAGTTTGACGAAACAATAA

Upstream 100 bases:

>100_bases
ATTTTGCCATTGGTCTAATCCTTCATGTCTAAAAAACGAATGGATTTTAATCGGCTGAAGATATAAAATCTAATCACTAT
TCTTTATACTAAATATAAAT

Downstream 100 bases:

>100_bases
TTGACGAACGTATTTGCAAAAAATTAGGGAAATTAGATCGCTTGTTATCACTAATACACTAGCTCGCATCTCCTTTTGGG
CTTACCCCAAAATGTCTTTT

Product: putative transcriptional regulator LysR-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MRDIRTVDLNLLKAFDALLQERNVTKAAQRLSVTQPAMSAMLNRLRDSFGDPLFVRVQHGIEPTARALALMPSVKTILAE
VNRMLRPVEFDPQTAEMTIKIASTDYGLEAIGTPFLSHLKQLAPKIRVAFLPAQDVDLLAQFEQARIDIALVSTQHIPAD
LHSKPLLTEHYVCVMRADHPMANQLLNLDNFCELDFAMMSYDGGQFYGVCDEALAKLGKTRRVSVSVNHFSLLPNILRTT
DVVALIPSRLSHHLTGLICKTLPLEVQGFSLQMAWHERTHQDPAYQWIRNLLVESLTKQ

Sequences:

>Translated_299_residues
MRDIRTVDLNLLKAFDALLQERNVTKAAQRLSVTQPAMSAMLNRLRDSFGDPLFVRVQHGIEPTARALALMPSVKTILAE
VNRMLRPVEFDPQTAEMTIKIASTDYGLEAIGTPFLSHLKQLAPKIRVAFLPAQDVDLLAQFEQARIDIALVSTQHIPAD
LHSKPLLTEHYVCVMRADHPMANQLLNLDNFCELDFAMMSYDGGQFYGVCDEALAKLGKTRRVSVSVNHFSLLPNILRTT
DVVALIPSRLSHHLTGLICKTLPLEVQGFSLQMAWHERTHQDPAYQWIRNLLVESLTKQ
>Mature_299_residues
MRDIRTVDLNLLKAFDALLQERNVTKAAQRLSVTQPAMSAMLNRLRDSFGDPLFVRVQHGIEPTARALALMPSVKTILAE
VNRMLRPVEFDPQTAEMTIKIASTDYGLEAIGTPFLSHLKQLAPKIRVAFLPAQDVDLLAQFEQARIDIALVSTQHIPAD
LHSKPLLTEHYVCVMRADHPMANQLLNLDNFCELDFAMMSYDGGQFYGVCDEALAKLGKTRRVSVSVNHFSLLPNILRTT
DVVALIPSRLSHHLTGLICKTLPLEVQGFSLQMAWHERTHQDPAYQWIRNLLVESLTKQ

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=301, Percent_Identity=28.9036544850498, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790147, Length=299, Percent_Identity=28.7625418060201, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789506, Length=170, Percent_Identity=28.2352941176471, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87081766, Length=264, Percent_Identity=24.2424242424242, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786820, Length=70, Percent_Identity=44.2857142857143, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1789204, Length=200, Percent_Identity=29.5, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33644; Mature: 33644

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS50931 HTH_LYSR ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDIRTVDLNLLKAFDALLQERNVTKAAQRLSVTQPAMSAMLNRLRDSFGDPLFVRVQHG
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECC
IEPTARALALMPSVKTILAEVNRMLRPVEFDPQTAEMTIKIASTDYGLEAIGTPFLSHLK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCHHHHCCHHHHHHH
QLAPKIRVAFLPAQDVDLLAQFEQARIDIALVSTQHIPADLHSKPLLTEHYVCVMRADHP
HHCCHHEEEEECCCCHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCHHCEEEEEECCCH
MANQLLNLDNFCELDFAMMSYDGGQFYGVCDEALAKLGKTRRVSVSVNHFSLLPNILRTT
HHHHHCCCCCHHHHHHHEEECCCCCEECHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHH
DVVALIPSRLSHHLTGLICKTLPLEVQGFSLQMAWHERTHQDPAYQWIRNLLVESLTKQ
HHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEEEEHHCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRDIRTVDLNLLKAFDALLQERNVTKAAQRLSVTQPAMSAMLNRLRDSFGDPLFVRVQHG
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECC
IEPTARALALMPSVKTILAEVNRMLRPVEFDPQTAEMTIKIASTDYGLEAIGTPFLSHLK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCHHHHCCHHHHHHH
QLAPKIRVAFLPAQDVDLLAQFEQARIDIALVSTQHIPADLHSKPLLTEHYVCVMRADHP
HHCCHHEEEEECCCCHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCHHCEEEEEECCCH
MANQLLNLDNFCELDFAMMSYDGGQFYGVCDEALAKLGKTRRVSVSVNHFSLLPNILRTT
HHHHHCCCCCHHHHHHHEEECCCCCEECHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHH
DVVALIPSRLSHHLTGLICKTLPLEVQGFSLQMAWHERTHQDPAYQWIRNLLVESLTKQ
HHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEEEEHHCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]