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The map label for this gene is yvaA [H]

Identifier: 126208648

GI number: 126208648

Start: 1357682

End: 1358725

Strand: Reverse

Name: yvaA [H]

Synonym: APL_1180

Alternate gene names: 126208648

Gene position: 1358725-1357682 (Counterclockwise)

Preceding gene: 126208654

Following gene: 126208647

Centisome position: 59.74

GC content: 43.3

Gene sequence:

>1044_bases
ATGATGAAAATTCTTAATGTTGCGATTGCCGGCAGCGGTTATTCCAGTCGCTTGTTCCATATTCCTTTTCTTAAAAATGA
CAAACGCTTCCATATTCAGAAAGTGTACGAGCGTACTACCGAGCGAGCAAAGGAATGGCTGCCGGATGTGAATATTGTGC
ATGAATATCAAGCGTTACTTACGCCGGAAATCGATTTGGTTATTATTACTACGCCGAACCAAACGCATTATGAGATGGTA
AAAAGCGCCTTATTAGCCGGTAAACACGTGTTGGTTGAAAAACCGTTAGTCGCAAGCTCGGCGGAGGCATTAGAACTGGA
ACGGTTAGCCAAACAGCAAAATGTTGTGTTGTACGTTTATCAAAACCGCCGTTGGGACAGCCATATTGCCACCGCAAAAG
AAGTTTTAGCTAAAAATTTAGTGGGCGAGGTCGTGGATTGCGAAATCCGCTTCGATCGTTATGCGAAAGGCAAAAATGCT
AAAGCATGGAAAGAAGCCGGCGATCGCGGTACCGGTTTAGTTTATGATTTGGGTGTACATTTAATCGATCAATCCATTTA
TCTGTTCGGTAAACCGCAAGCGGTGTTTGCCGATATTCGTTATCAACACGACGGCGCATTGGTGGATGATAACTTTGATA
TACATCTTTATTATGCAAACGGCTTAACGGTTGCCTTACAAGCATCTAAATACGCACGAGAGCCAAGTCCGACCTTCGTA
TTACACGGTAAAAACGGTTCTTATGTGAAAAAATCGCTCGACAGCCAAGAAGCGCATTTAAACAGCGGAGTAATGCCGAT
TGGCGATTGGAACGTTGAGCCGGAAAGCGAATGGGGCGTATTGCATACGGAAATTGACGGCGCAGTCATTCGTAAGCCTT
ATCCGAATGCGCAAGCCAGTTATCAAAATTTGCTAGATGATTTGTATCAAACGATTACCGCAGGTATTGAACCTATCGTT
AAATTAGCGGAAGTGATATTGGTTTTACAGATTATCGAAGCGGCATTTGAAAGTGCAAGTAATGGGCAGAAAATCAAGTT
GTAA

Upstream 100 bases:

>100_bases
GATTCGGATTACTATAAACAATAACCATAGCTAGAAAAAGCGGGGCATTTTTTTCTTTTTCTTCTATACTGGATTTAATT
TTCTTTAATCAGGAGCATAA

Downstream 100 bases:

>100_bases
GAAAAATTTGAGATGACAAGCGGTGGAATTTGTAAAATATTTTGCAAATTTCACCGCTTTTTGTTTTGCTAAATAGCCTT
TAAATCTCTTGATCTCTCTA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MMKILNVAIAGSGYSSRLFHIPFLKNDKRFHIQKVYERTTERAKEWLPDVNIVHEYQALLTPEIDLVIITTPNQTHYEMV
KSALLAGKHVLVEKPLVASSAEALELERLAKQQNVVLYVYQNRRWDSHIATAKEVLAKNLVGEVVDCEIRFDRYAKGKNA
KAWKEAGDRGTGLVYDLGVHLIDQSIYLFGKPQAVFADIRYQHDGALVDDNFDIHLYYANGLTVALQASKYAREPSPTFV
LHGKNGSYVKKSLDSQEAHLNSGVMPIGDWNVEPESEWGVLHTEIDGAVIRKPYPNAQASYQNLLDDLYQTITAGIEPIV
KLAEVILVLQIIEAAFESASNGQKIKL

Sequences:

>Translated_347_residues
MMKILNVAIAGSGYSSRLFHIPFLKNDKRFHIQKVYERTTERAKEWLPDVNIVHEYQALLTPEIDLVIITTPNQTHYEMV
KSALLAGKHVLVEKPLVASSAEALELERLAKQQNVVLYVYQNRRWDSHIATAKEVLAKNLVGEVVDCEIRFDRYAKGKNA
KAWKEAGDRGTGLVYDLGVHLIDQSIYLFGKPQAVFADIRYQHDGALVDDNFDIHLYYANGLTVALQASKYAREPSPTFV
LHGKNGSYVKKSLDSQEAHLNSGVMPIGDWNVEPESEWGVLHTEIDGAVIRKPYPNAQASYQNLLDDLYQTITAGIEPIV
KLAEVILVLQIIEAAFESASNGQKIKL
>Mature_347_residues
MMKILNVAIAGSGYSSRLFHIPFLKNDKRFHIQKVYERTTERAKEWLPDVNIVHEYQALLTPEIDLVIITTPNQTHYEMV
KSALLAGKHVLVEKPLVASSAEALELERLAKQQNVVLYVYQNRRWDSHIATAKEVLAKNLVGEVVDCEIRFDRYAKGKNA
KAWKEAGDRGTGLVYDLGVHLIDQSIYLFGKPQAVFADIRYQHDGALVDDNFDIHLYYANGLTVALQASKYAREPSPTFV
LHGKNGSYVKKSLDSQEAHLNSGVMPIGDWNVEPESEWGVLHTEIDGAVIRKPYPNAQASYQNLLDDLYQTITAGIEPIV
KLAEVILVLQIIEAAFESASNGQKIKL

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1789848, Length=343, Percent_Identity=36.1516034985423, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI87081947, Length=349, Percent_Identity=34.3839541547278, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI145693182, Length=262, Percent_Identity=24.8091603053435, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787574, Length=192, Percent_Identity=26.0416666666667, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082405, Length=303, Percent_Identity=22.4422442244224, Blast_Score=65, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323975, Length=223, Percent_Identity=26.457399103139, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24581117, Length=259, Percent_Identity=28.1853281853282, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38984; Mature: 38984

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKILNVAIAGSGYSSRLFHIPFLKNDKRFHIQKVYERTTERAKEWLPDVNIVHEYQALL
CCEEEEEEEECCCCCCCEEECCEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TPEIDLVIITTPNQTHYEMVKSALLAGKHVLVEKPLVASSAEALELERLAKQQNVVLYVY
CCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHCCEEEEEE
QNRRWDSHIATAKEVLAKNLVGEVVDCEIRFDRYAKGKNAKAWKEAGDRGTGLVYDLGVH
ECCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCHHHHCCCCCCCEEEEHHHH
LIDQSIYLFGKPQAVFADIRYQHDGALVDDNFDIHLYYANGLTVALQASKYAREPSPTFV
HHCCEEEEEECCCEEEEEEEECCCCCEEECCCEEEEEEECCEEEEEECHHHCCCCCCEEE
LHGKNGSYVKKSLDSQEAHLNSGVMPIGDWNVEPESEWGVLHTEIDGAVIRKPYPNAQAS
EECCCCCHHHHHCCCHHHHHCCCCEECCCCCCCCCCCCCEEEEECCCEEEECCCCCHHHH
YQNLLDDLYQTITAGIEPIVKLAEVILVLQIIEAAFESASNGQKIKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECC
>Mature Secondary Structure
MMKILNVAIAGSGYSSRLFHIPFLKNDKRFHIQKVYERTTERAKEWLPDVNIVHEYQALL
CCEEEEEEEECCCCCCCEEECCEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TPEIDLVIITTPNQTHYEMVKSALLAGKHVLVEKPLVASSAEALELERLAKQQNVVLYVY
CCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHCCEEEEEE
QNRRWDSHIATAKEVLAKNLVGEVVDCEIRFDRYAKGKNAKAWKEAGDRGTGLVYDLGVH
ECCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCHHHHCCCCCCCEEEEHHHH
LIDQSIYLFGKPQAVFADIRYQHDGALVDDNFDIHLYYANGLTVALQASKYAREPSPTFV
HHCCEEEEEECCCEEEEEEEECCCCCEEECCCEEEEEEECCEEEEEECHHHCCCCCCEEE
LHGKNGSYVKKSLDSQEAHLNSGVMPIGDWNVEPESEWGVLHTEIDGAVIRKPYPNAQAS
EECCCCCHHHHHCCCHHHHHCCCCEECCCCCCCCCCCCCEEEEECCCEEEECCCCCHHHH
YQNLLDDLYQTITAGIEPIVKLAEVILVLQIIEAAFESASNGQKIKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]