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The map label for this gene is csd [H]

Identifier: 126208595

GI number: 126208595

Start: 1300870

End: 1302072

Strand: Reverse

Name: csd [H]

Synonym: APL_1125

Alternate gene names: 126208595

Gene position: 1302072-1300870 (Counterclockwise)

Preceding gene: 126208596

Following gene: 126208594

Centisome position: 57.25

GC content: 44.06

Gene sequence:

>1203_bases
ATGAATATGCAGCAAACGGAAGCGTTTAGATCTCAATTTCCTTTTTTTCGACAACAAGCGGAATGGAGTTATCTGGACTC
CGCCGCCACGACTTTAAAACCACAGATTCTCATTGATAGTACGGTCGAATTTTATGCTTCGGCTGGGTCGGTACATCGCA
GCCAATACGATCTGATACAAAGCCGAGCTTATGAGCGAGCGAGAGATTTAGTCGCTTCTCGTTTTAATACGGAATCTCGC
AATGCGGTGATTTGGACAAGCGGTACCACCCATGCGATTAATTTAGTGGCGTACGGTTTGGAACATTTACTGGAAGCGGG
AGATGAAATTGTGATTTCGGTTGCCGAACATCATGCGAATTTTATTCCGTGGCAGCAGTTAGCACAGCGTAAGCAAGCGA
AATTAATTGTGTTGCCGTTAGATGCAAATTTTCAGTTAAATCCGACCGCTTTAACGCAAGCCGTTTCCGAAAGAACTAAA
ATCGTTGCCTTGAATTTAGTTTCAAACGTAACCGGCGTACGTCAGCCGGTCGAACGGCTGATCCCGATTATTCGCCGCCG
TTCCAATGCAAAAATTTTATTAGATTGCGCGCAAGCGGTATGTTGCGAAAGAGTGGACGTACAAAAACTGGATGCGGATT
TTTATGCCTTTTCGGCGCATAAAATGTATGGACCGACCGGTGTCGGTGTTTTAACCGGAAAATTGCAAAGTTTAGAGCAA
ATTCGACCGCTGTTTTTCGGCGGTAAAATGTTGGAAGATATTTCGGAATCCGCACTTTCCGTTGCCGCTTTACCTTATCG
CTTGGAAGCCGGTACGCCGAATATCGCCGGAATCATTGGTTTCGGCAAAACATTGGAATGGCTCGAACAATGGGATTTCG
AAGCATTGAATCATGTTGTGGATAATCTGGCGGAAGAAGCCTACAAGCGGTTAAAAAAGTATAAAAATATTCGAATTTTT
TCTCAGCCGAATTGTTCTATCATTAGTTTTGCATTTGACGGGATTCATCATGCCGATATTGCGGCGATTATGACCGAAAG
TAAAATCGCGTTACGTAGCGGAGAGCATTGTGCGAAGCCGTATCTGCATTATTTGCAACAAAGCGGCACACTAAGAATTT
CGTTGGCGCATTATACTTCGCCCGACGAATTGGATAAATTCTTCAAGGCGTTGGATTTAGCCTTGGATATTTTGCTTGAT
TAG

Upstream 100 bases:

>100_bases
AAAGTGCGAAGCGTTATTTCGATCTATGCGGTTCTAAAACGATGGACGGTAATCGTGACGGTATTCCTTGTAATAAATTG
TATCGGGAGGCGGTGCGTTA

Downstream 100 bases:

>100_bases
ATCAAAAAAAGATGAAATAGCACTAGAATGAATACCCTAAATAAGGTAATCTTGCCGCCAATTTTCGATTTATTTTAAAA
TTTAAATTTATAGCAAAAGG

Product: putative cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MNMQQTEAFRSQFPFFRQQAEWSYLDSAATTLKPQILIDSTVEFYASAGSVHRSQYDLIQSRAYERARDLVASRFNTESR
NAVIWTSGTTHAINLVAYGLEHLLEAGDEIVISVAEHHANFIPWQQLAQRKQAKLIVLPLDANFQLNPTALTQAVSERTK
IVALNLVSNVTGVRQPVERLIPIIRRRSNAKILLDCAQAVCCERVDVQKLDADFYAFSAHKMYGPTGVGVLTGKLQSLEQ
IRPLFFGGKMLEDISESALSVAALPYRLEAGTPNIAGIIGFGKTLEWLEQWDFEALNHVVDNLAEEAYKRLKKYKNIRIF
SQPNCSIISFAFDGIHHADIAAIMTESKIALRSGEHCAKPYLHYLQQSGTLRISLAHYTSPDELDKFFKALDLALDILLD

Sequences:

>Translated_400_residues
MNMQQTEAFRSQFPFFRQQAEWSYLDSAATTLKPQILIDSTVEFYASAGSVHRSQYDLIQSRAYERARDLVASRFNTESR
NAVIWTSGTTHAINLVAYGLEHLLEAGDEIVISVAEHHANFIPWQQLAQRKQAKLIVLPLDANFQLNPTALTQAVSERTK
IVALNLVSNVTGVRQPVERLIPIIRRRSNAKILLDCAQAVCCERVDVQKLDADFYAFSAHKMYGPTGVGVLTGKLQSLEQ
IRPLFFGGKMLEDISESALSVAALPYRLEAGTPNIAGIIGFGKTLEWLEQWDFEALNHVVDNLAEEAYKRLKKYKNIRIF
SQPNCSIISFAFDGIHHADIAAIMTESKIALRSGEHCAKPYLHYLQQSGTLRISLAHYTSPDELDKFFKALDLALDILLD
>Mature_400_residues
MNMQQTEAFRSQFPFFRQQAEWSYLDSAATTLKPQILIDSTVEFYASAGSVHRSQYDLIQSRAYERARDLVASRFNTESR
NAVIWTSGTTHAINLVAYGLEHLLEAGDEIVISVAEHHANFIPWQQLAQRKQAKLIVLPLDANFQLNPTALTQAVSERTK
IVALNLVSNVTGVRQPVERLIPIIRRRSNAKILLDCAQAVCCERVDVQKLDADFYAFSAHKMYGPTGVGVLTGKLQSLEQ
IRPLFFGGKMLEDISESALSVAALPYRLEAGTPNIAGIIGFGKTLEWLEQWDFEALNHVVDNLAEEAYKRLKKYKNIRIF
SQPNCSIISFAFDGIHHADIAAIMTESKIALRSGEHCAKPYLHYLQQSGTLRISLAHYTSPDELDKFFKALDLALDILLD

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=383, Percent_Identity=24.5430809399478, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI156713448, Length=336, Percent_Identity=25.297619047619, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI1789175, Length=404, Percent_Identity=42.5742574257426, Blast_Score=324, Evalue=7e-90,
Organism=Escherichia coli, GI1787970, Length=397, Percent_Identity=37.5314861460957, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI48994898, Length=389, Percent_Identity=24.9357326478149, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25143064, Length=383, Percent_Identity=24.0208877284595, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6319831, Length=388, Percent_Identity=24.2268041237113, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI20129463, Length=379, Percent_Identity=25.5936675461741, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 44915; Mature: 44915

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMQQTEAFRSQFPFFRQQAEWSYLDSAATTLKPQILIDSTVEFYASAGSVHRSQYDLIQ
CCCHHHHHHHHHCCHHHHHCCHHHHHHHHHHCCCEEEEHHHHHHHHCCCHHHHHHHHHHH
SRAYERARDLVASRFNTESRNAVIWTSGTTHAINLVAYGLEHLLEAGDEIVISVAEHHAN
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHCCC
FIPWQQLAQRKQAKLIVLPLDANFQLNPTALTQAVSERTKIVALNLVSNVTGVRQPVERL
CCCHHHHHHHHCCEEEEEEECCCCEECHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHH
IPIIRRRSNAKILLDCAQAVCCERVDVQKLDADFYAFSAHKMYGPTGVGVLTGKLQSLEQ
HHHHHCCCCCEEHHHHHHHHHHCCCCHHHHCCCHHEEECCCCCCCCCCHHHHHHHHHHHH
IRPLFFGGKMLEDISESALSVAALPYRLEAGTPNIAGIIGFGKTLEWLEQWDFEALNHVV
HHHHHHCHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCHHHHHHHHCCHHHHHHHH
DNLAEEAYKRLKKYKNIRIFSQPNCSIISFAFDGIHHADIAAIMTESKIALRSGEHCAKP
HHHHHHHHHHHHHHCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHH
YLHYLQQSGTLRISLAHYTSPDELDKFFKALDLALDILLD
HHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNMQQTEAFRSQFPFFRQQAEWSYLDSAATTLKPQILIDSTVEFYASAGSVHRSQYDLIQ
CCCHHHHHHHHHCCHHHHHCCHHHHHHHHHHCCCEEEEHHHHHHHHCCCHHHHHHHHHHH
SRAYERARDLVASRFNTESRNAVIWTSGTTHAINLVAYGLEHLLEAGDEIVISVAEHHAN
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHCCC
FIPWQQLAQRKQAKLIVLPLDANFQLNPTALTQAVSERTKIVALNLVSNVTGVRQPVERL
CCCHHHHHHHHCCEEEEEEECCCCEECHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHH
IPIIRRRSNAKILLDCAQAVCCERVDVQKLDADFYAFSAHKMYGPTGVGVLTGKLQSLEQ
HHHHHCCCCCEEHHHHHHHHHHCCCCHHHHCCCHHEEECCCCCCCCCCHHHHHHHHHHHH
IRPLFFGGKMLEDISESALSVAALPYRLEAGTPNIAGIIGFGKTLEWLEQWDFEALNHVV
HHHHHHCHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCHHHHHHHHCCHHHHHHHH
DNLAEEAYKRLKKYKNIRIFSQPNCSIISFAFDGIHHADIAAIMTESKIALRSGEHCAKP
HHHHHHHHHHHHHHCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHH
YLHYLQQSGTLRISLAHYTSPDELDKFFKALDLALDILLD
HHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]