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The map label for this gene is nrfE [H]

Identifier: 126208524

GI number: 126208524

Start: 1220471

End: 1222387

Strand: Reverse

Name: nrfE [H]

Synonym: APL_1052

Alternate gene names: 126208524

Gene position: 1222387-1220471 (Counterclockwise)

Preceding gene: 126208525

Following gene: 126208523

Centisome position: 53.74

GC content: 45.28

Gene sequence:

>1917_bases
ATGCTTCCTGAGTTGGGTTATTTTACGTTAATTTTTGCAGCGGTTGCCGCTGTTTGCCAAGTGGGGCTGACATTGTGGGG
AGAGATCACTAAGAAAACGGATTTTCTTCGATACAATGCGTTGTTGAGCAGCCTGCAAACGGTAGGTTGTTTGTCGTCGT
TCGGGATATTGGCTTACGCTTTTTTGAGTGATGATTTTTCGGTGATTTATGTCGCCCAACATTCCAACAGCCAATTACCG
GATTTCTTTAAATTTGCGGCGACTTGGGGCGGACACGAAGGCTCAATGCTGTTTTGGCTGACCGCTCTGACACTATGGAC
CAGCGTTTTTTGCATTTTTTCGGATAAATCTGACCGCTTGTTTAATCAGCGAACCTTGGCGGTATTAGGTTTAATCAGCC
TTGGATTTATGCTCTTTATTTTATTGGTTTCCAATCCGTTTGAGCGTAGTTTTCCGCCTCCGCCGGAGGGCAGAGATCTT
AACCCGATGTTGCAAGACGTAGGGCTTATCTTCCATCCGCCTTTACTTTATTTAGGTTATGTCGGTTTTGCGGTAAGCTT
TGCAATGGTCGTGGCGGCATTAATGGAAGGTATGCTGGATGCCGCAGTAGTGCGTTGGATTCGACCTTGGACAATGATCT
CTTGGGGCTTTCTTACCGCAGGGATTATTCTCGGTGCATGGTGGGCGTATTATGAACTGGGCTGGGGCGGCTGGTGGTTC
TGGGATCCGGTTGAAAACGCTTCGTTAATGCCGTGGCTATTGGGAACCGCATTAGTGCATAGCTTGGTTGTGAGCGAGCA
GCGCGGTATTTTTAACTATTGGACGATTTTACTGGCGATTTTTGCTTTTGCATTGAGCTTACTCGGGACTTTTATCGTGC
GTTCCGGCGTACTCACTTCGGTACATGCGTTTGCAGTTGATCCGGATAGAGGAATGGCACTGCTTATTCTGTTTTTCAGT
TTAAGTTTTATTGCGTTAGCCTTGTTCGCTTTTAGAGTGAATTTGTGGCAGGGCGAAGTGCGTTTCCAACCGCTATCCAA
AGAAACCGCTTTATTATTAGTAAACGGCTTATTGAGCGTAGCGACTTCGGTTGTCCTACTCGGGACTTTTTACCCGATGA
TTTTTACGGCGATGAATTGGGGCTCGATTTCGGTCGGCGCACCTTATTTCAATAATGTTTTTGCACCGTTGGCATTATTA
TTAATGACGGTAATGGGATTTGCCGTCGTATTGCGTTGGAAGCAAATTCCGTCAAAACAAATTCTGATGAAATTATGGCT
GTTACCGGTAGCGGTAGGATTGAGTTTCCTATTGATTCAACAAACGATTTCGCAAACAAAGTTGTATCAATTTGGCGTCT
TGCCGACGGTATTCGTCAGCCTTGCCGTTTGGATTATTCTGACGCATTTGCCTTATTCGGCGAAATTTCTGAAAATCCGA
CCGCTTGCTATGCGTTTGGCGCATATCGGTTTTGCGATTTGTGTTATTGGTGCCATGATGAACAGTTATTACGGCGATGA
AATCGGCGTACGTTTAAAACCGCAGCAACAGGCGGATCTTGCCGGATTTACCTTTAAATATGAAGATTATCAGGATGGGA
TCGGTGCGAACTATACGTCCGAAAATGCGTTATTTAGCATAAGCAAAGCGGGAAAAACGCTTGCGACGGTAGTGGCGGAG
CGCCGCTATTACGATATTCGTACCATGACGATGTCGGAAGTCGGGCTTTATCATCACGGCTTGGACGATATTTATATTGT
GATGGGCGATAAATTCGGCAATTTGGAATATGCTTTCCGTTTGCATTATAAGCCTTATGTCGGCGCATTATGGCTTGGCG
GTATTATTATGGTGATAGCTTCCATACTTGCCTTATTCGGTTATCGTCGAAAATCGGATCTTACAGCGGATAAATAA

Upstream 100 bases:

>100_bases
ATAAAGGTAACAAATCTTTATGATTAGCCTTAGTAAAACAAGCGGTTATTTTTAAGATTTTCTTTGTAAAATCAGATGTT
ATTTATTGAAGTGGGTTCTT

Downstream 100 bases:

>100_bases
TATGAAAAAAACCTTTTTATTTTTACCTTTATTATTGTTGATTGCACTGGTAGCGTTTTTAACCGTACCGTTAATGAATA
AGGATGCCCTTTCGCCGACC

Product: cytochrome c-type biogenesis protein NrfE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MLPELGYFTLIFAAVAAVCQVGLTLWGEITKKTDFLRYNALLSSLQTVGCLSSFGILAYAFLSDDFSVIYVAQHSNSQLP
DFFKFAATWGGHEGSMLFWLTALTLWTSVFCIFSDKSDRLFNQRTLAVLGLISLGFMLFILLVSNPFERSFPPPPEGRDL
NPMLQDVGLIFHPPLLYLGYVGFAVSFAMVVAALMEGMLDAAVVRWIRPWTMISWGFLTAGIILGAWWAYYELGWGGWWF
WDPVENASLMPWLLGTALVHSLVVSEQRGIFNYWTILLAIFAFALSLLGTFIVRSGVLTSVHAFAVDPDRGMALLILFFS
LSFIALALFAFRVNLWQGEVRFQPLSKETALLLVNGLLSVATSVVLLGTFYPMIFTAMNWGSISVGAPYFNNVFAPLALL
LMTVMGFAVVLRWKQIPSKQILMKLWLLPVAVGLSFLLIQQTISQTKLYQFGVLPTVFVSLAVWIILTHLPYSAKFLKIR
PLAMRLAHIGFAICVIGAMMNSYYGDEIGVRLKPQQQADLAGFTFKYEDYQDGIGANYTSENALFSISKAGKTLATVVAE
RRYYDIRTMTMSEVGLYHHGLDDIYIVMGDKFGNLEYAFRLHYKPYVGALWLGGIIMVIASILALFGYRRKSDLTADK

Sequences:

>Translated_638_residues
MLPELGYFTLIFAAVAAVCQVGLTLWGEITKKTDFLRYNALLSSLQTVGCLSSFGILAYAFLSDDFSVIYVAQHSNSQLP
DFFKFAATWGGHEGSMLFWLTALTLWTSVFCIFSDKSDRLFNQRTLAVLGLISLGFMLFILLVSNPFERSFPPPPEGRDL
NPMLQDVGLIFHPPLLYLGYVGFAVSFAMVVAALMEGMLDAAVVRWIRPWTMISWGFLTAGIILGAWWAYYELGWGGWWF
WDPVENASLMPWLLGTALVHSLVVSEQRGIFNYWTILLAIFAFALSLLGTFIVRSGVLTSVHAFAVDPDRGMALLILFFS
LSFIALALFAFRVNLWQGEVRFQPLSKETALLLVNGLLSVATSVVLLGTFYPMIFTAMNWGSISVGAPYFNNVFAPLALL
LMTVMGFAVVLRWKQIPSKQILMKLWLLPVAVGLSFLLIQQTISQTKLYQFGVLPTVFVSLAVWIILTHLPYSAKFLKIR
PLAMRLAHIGFAICVIGAMMNSYYGDEIGVRLKPQQQADLAGFTFKYEDYQDGIGANYTSENALFSISKAGKTLATVVAE
RRYYDIRTMTMSEVGLYHHGLDDIYIVMGDKFGNLEYAFRLHYKPYVGALWLGGIIMVIASILALFGYRRKSDLTADK
>Mature_638_residues
MLPELGYFTLIFAAVAAVCQVGLTLWGEITKKTDFLRYNALLSSLQTVGCLSSFGILAYAFLSDDFSVIYVAQHSNSQLP
DFFKFAATWGGHEGSMLFWLTALTLWTSVFCIFSDKSDRLFNQRTLAVLGLISLGFMLFILLVSNPFERSFPPPPEGRDL
NPMLQDVGLIFHPPLLYLGYVGFAVSFAMVVAALMEGMLDAAVVRWIRPWTMISWGFLTAGIILGAWWAYYELGWGGWWF
WDPVENASLMPWLLGTALVHSLVVSEQRGIFNYWTILLAIFAFALSLLGTFIVRSGVLTSVHAFAVDPDRGMALLILFFS
LSFIALALFAFRVNLWQGEVRFQPLSKETALLLVNGLLSVATSVVLLGTFYPMIFTAMNWGSISVGAPYFNNVFAPLALL
LMTVMGFAVVLRWKQIPSKQILMKLWLLPVAVGLSFLLIQQTISQTKLYQFGVLPTVFVSLAVWIILTHLPYSAKFLKIR
PLAMRLAHIGFAICVIGAMMNSYYGDEIGVRLKPQQQADLAGFTFKYEDYQDGIGANYTSENALFSISKAGKTLATVVAE
RRYYDIRTMTMSEVGLYHHGLDDIYIVMGDKFGNLEYAFRLHYKPYVGALWLGGIIMVIASILALFGYRRKSDLTADK

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=647, Percent_Identity=41.5765069551777, Blast_Score=471, Evalue=1e-134,
Organism=Escherichia coli, GI1790511, Length=579, Percent_Identity=41.6234887737478, Blast_Score=365, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568
- InterPro:   IPR003570
- InterPro:   IPR017563 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 71342; Mature: 71342

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPELGYFTLIFAAVAAVCQVGLTLWGEITKKTDFLRYNALLSSLQTVGCLSSFGILAYA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLSDDFSVIYVAQHSNSQLPDFFKFAATWGGHEGSMLFWLTALTLWTSVFCIFSDKSDRL
HHCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEECCCCHHH
FNQRTLAVLGLISLGFMLFILLVSNPFERSFPPPPEGRDLNPMLQDVGLIFHPPLLYLGY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCHHHCCHHHHHHH
VGFAVSFAMVVAALMEGMLDAAVVRWIRPWTMISWGFLTAGIILGAWWAYYELGWGGWWF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
WDPVENASLMPWLLGTALVHSLVVSEQRGIFNYWTILLAIFAFALSLLGTFIVRSGVLTS
ECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
VHAFAVDPDRGMALLILFFSLSFIALALFAFRVNLWQGEVRFQPLSKETALLLVNGLLSV
HHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHH
ATSVVLLGTFYPMIFTAMNWGSISVGAPYFNNVFAPLALLLMTVMGFAVVLRWKQIPSKQ
HHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
ILMKLWLLPVAVGLSFLLIQQTISQTKLYQFGVLPTVFVSLAVWIILTHLPYSAKFLKIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEH
PLAMRLAHIGFAICVIGAMMNSYYGDEIGVRLKPQQQADLAGFTFKYEDYQDGIGANYTS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCCCCC
ENALFSISKAGKTLATVVAERRYYDIRTMTMSEVGLYHHGLDDIYIVMGDKFGNLEYAFR
CCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEE
LHYKPYVGALWLGGIIMVIASILALFGYRRKSDLTADK
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLPELGYFTLIFAAVAAVCQVGLTLWGEITKKTDFLRYNALLSSLQTVGCLSSFGILAYA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLSDDFSVIYVAQHSNSQLPDFFKFAATWGGHEGSMLFWLTALTLWTSVFCIFSDKSDRL
HHCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEECCCCHHH
FNQRTLAVLGLISLGFMLFILLVSNPFERSFPPPPEGRDLNPMLQDVGLIFHPPLLYLGY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCHHHCCHHHHHHH
VGFAVSFAMVVAALMEGMLDAAVVRWIRPWTMISWGFLTAGIILGAWWAYYELGWGGWWF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
WDPVENASLMPWLLGTALVHSLVVSEQRGIFNYWTILLAIFAFALSLLGTFIVRSGVLTS
ECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
VHAFAVDPDRGMALLILFFSLSFIALALFAFRVNLWQGEVRFQPLSKETALLLVNGLLSV
HHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHH
ATSVVLLGTFYPMIFTAMNWGSISVGAPYFNNVFAPLALLLMTVMGFAVVLRWKQIPSKQ
HHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
ILMKLWLLPVAVGLSFLLIQQTISQTKLYQFGVLPTVFVSLAVWIILTHLPYSAKFLKIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEH
PLAMRLAHIGFAICVIGAMMNSYYGDEIGVRLKPQQQADLAGFTFKYEDYQDGIGANYTS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCCCCC
ENALFSISKAGKTLATVVAERRYYDIRTMTMSEVGLYHHGLDDIYIVMGDKFGNLEYAFR
CCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEE
LHYKPYVGALWLGGIIMVIASILALFGYRRKSDLTADK
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]