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The map label for this gene is dinP

Identifier: 126208514

GI number: 126208514

Start: 1207863

End: 1208933

Strand: Reverse

Name: dinP

Synonym: APL_1040

Alternate gene names: 126208514

Gene position: 1208933-1207863 (Counterclockwise)

Preceding gene: 126208516

Following gene: 126208513

Centisome position: 53.15

GC content: 44.54

Gene sequence:

>1071_bases
ATGGCAACGCAACGCAAAATAATTCACATTGATATGGACTGCTTTTATGCTGCGATTGAAATGCGAGAAAATCCGGCGTT
AATAGGCAAGCCGGTCGCAGTCGGCGGTTCTGTTGAAGGTCGAGGCGTGCTGACCACTTGCAATTACGAAGCCAGAAAAT
TCGGTTTACACAGTGCAATGCCGACTGCGCAGGCGTTAAAACGCTGTCCGAATCTGATTCTAGTACCGGTAAATATGCCG
TTATACAAAGCGGTTTCCGAGCAGATTCATCAAATATTCCGCCGTTATACCGATATCGTCGAACTGCTTTCATTAGATGA
GGCTTATTTAGATGTGACGGATTGCCGGCAATGTTCCGGCTCAGCCACTTGGATTGCCCAAGAAATTCGAGATGCAATTT
GGAACGAGCTGCATTTAACCGCTTCCGCCGGCATTGCCCCGCTCAAATTTTTGGCAAAAATCGCTTCGGATCAAAATAAG
CCTAACGGGCAATTTGTCATTTCGCCGGAAAATATGACCGCTTTTATTTATGATTTGCCGCTCAAAAAGATCCCGAGAGT
CGGTAAGGTAACCAATGAAAAATTAGCACAGCTGGGATTACATACTTGCGGCGATATTCAGCATAGCGATAAAGCTTTTA
TTTACAAGACGTTTGGCAAATTCGGGCAACGACTTTGGGAGTTCAGTCACGCAATTGATAATCGAAAAATCGAAGCGAAT
CGACCTCGTAAATCTTTAGCGGTCGAAAATACGTTACCGACTGATATTTGGCATTTAGCGGAAGCGGAGCAAATCGTTGA
TGAGCTGTTTAAAAAACTGGTTTTTCGGCTACAACGAAATTGGGGCGAACGTTCATTACAAGAATTTAAAAAATTAGCGA
TTAAACTAAAGTTCGGCGATTTCACGCAAACCACCTTGGAACGAACTACCGACGGGCTTTCGCGAGAGCGTTTTATCGAG
TTGCTTCAACAGGTGTGGCAGCGGACAAATCGGCGTTCGGTGCGTTTAATCGGGCTTTCGGTGCATTACCCGACGGAAAA
AGTTAAAAAACAGTTAAATTTGTGGGAATAA

Upstream 100 bases:

>100_bases
TTCCTTATCATTATTTATTTTTGGGTTGAAATTTTAACGGTAACCACATAAAATGAAACTGTTTTTATATACAGTTGGTT
TTATTTATAAGCAATCAAAA

Downstream 100 bases:

>100_bases
TTATTGTCAAACGCTTGAATTCTTATAGAATTACCCCTATTTAGTGACTAGTTTTTCCTCACTCTTTTTTGGAGATTTAT
TTACCTATGGCAAAAAGAAT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MATQRKIIHIDMDCFYAAIEMRENPALIGKPVAVGGSVEGRGVLTTCNYEARKFGLHSAMPTAQALKRCPNLILVPVNMP
LYKAVSEQIHQIFRRYTDIVELLSLDEAYLDVTDCRQCSGSATWIAQEIRDAIWNELHLTASAGIAPLKFLAKIASDQNK
PNGQFVISPENMTAFIYDLPLKKIPRVGKVTNEKLAQLGLHTCGDIQHSDKAFIYKTFGKFGQRLWEFSHAIDNRKIEAN
RPRKSLAVENTLPTDIWHLAEAEQIVDELFKKLVFRLQRNWGERSLQEFKKLAIKLKFGDFTQTTLERTTDGLSRERFIE
LLQQVWQRTNRRSVRLIGLSVHYPTEKVKKQLNLWE

Sequences:

>Translated_356_residues
MATQRKIIHIDMDCFYAAIEMRENPALIGKPVAVGGSVEGRGVLTTCNYEARKFGLHSAMPTAQALKRCPNLILVPVNMP
LYKAVSEQIHQIFRRYTDIVELLSLDEAYLDVTDCRQCSGSATWIAQEIRDAIWNELHLTASAGIAPLKFLAKIASDQNK
PNGQFVISPENMTAFIYDLPLKKIPRVGKVTNEKLAQLGLHTCGDIQHSDKAFIYKTFGKFGQRLWEFSHAIDNRKIEAN
RPRKSLAVENTLPTDIWHLAEAEQIVDELFKKLVFRLQRNWGERSLQEFKKLAIKLKFGDFTQTTLERTTDGLSRERFIE
LLQQVWQRTNRRSVRLIGLSVHYPTEKVKKQLNLWE
>Mature_355_residues
ATQRKIIHIDMDCFYAAIEMRENPALIGKPVAVGGSVEGRGVLTTCNYEARKFGLHSAMPTAQALKRCPNLILVPVNMPL
YKAVSEQIHQIFRRYTDIVELLSLDEAYLDVTDCRQCSGSATWIAQEIRDAIWNELHLTASAGIAPLKFLAKIASDQNKP
NGQFVISPENMTAFIYDLPLKKIPRVGKVTNEKLAQLGLHTCGDIQHSDKAFIYKTFGKFGQRLWEFSHAIDNRKIEANR
PRKSLAVENTLPTDIWHLAEAEQIVDELFKKLVFRLQRNWGERSLQEFKKLAIKLKFGDFTQTTLERTTDGLSRERFIEL
LQQVWQRTNRRSVRLIGLSVHYPTEKVKKQLNLWE

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI84043967, Length=328, Percent_Identity=29.8780487804878, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI154350220, Length=313, Percent_Identity=30.9904153354633, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI7706681, Length=329, Percent_Identity=29.1793313069909, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI7705344, Length=107, Percent_Identity=50.4672897196262, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI5729982, Length=128, Percent_Identity=38.28125, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786425, Length=351, Percent_Identity=53.8461538461538, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI1787432, Length=217, Percent_Identity=30.4147465437788, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193205700, Length=397, Percent_Identity=29.9748110831234, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI17537959, Length=227, Percent_Identity=27.7533039647577, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI193205702, Length=342, Percent_Identity=26.9005847953216, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI115534089, Length=162, Percent_Identity=34.5679012345679, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19923006, Length=324, Percent_Identity=28.0864197530864, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI21355641, Length=320, Percent_Identity=29.6875, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24644984, Length=320, Percent_Identity=29.6875, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24668444, Length=118, Percent_Identity=30.5084745762712, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO4_ACTP2 (A3N148)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053739.1
- ProteinModelPortal:   A3N148
- SMR:   A3N148
- STRING:   A3N148
- GeneID:   4848671
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1040
- eggNOG:   COG0389
- HOGENOM:   HBG734504
- OMA:   QAMARQE
- PhylomeDB:   A3N148
- ProtClustDB:   PRK02406
- BioCyc:   APLE416269:APL_1040-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 40809; Mature: 40678

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 107-107

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQRKIIHIDMDCFYAAIEMRENPALIGKPVAVGGSVEGRGVLTTCNYEARKFGLHSAM
CCCCCEEEEEEHHHHHHHHHHCCCCCEECCCEEECCCCCCCEEEEECCCHHHHHCCHHCC
PTAQALKRCPNLILVPVNMPLYKAVSEQIHQIFRRYTDIVELLSLDEAYLDVTDCRQCSG
CHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCC
SATWIAQEIRDAIWNELHLTASAGIAPLKFLAKIASDQNKPNGQFVISPENMTAFIYDLP
CHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECC
LKKIPRVGKVTNEKLAQLGLHTCGDIQHSDKAFIYKTFGKFGQRLWEFSHAIDNRKIEAN
HHHCCCCCCHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RPRKSLAVENTLPTDIWHLAEAEQIVDELFKKLVFRLQRNWGERSLQEFKKLAIKLKFGD
CCHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCC
FTQTTLERTTDGLSRERFIELLQQVWQRTNRRSVRLIGLSVHYPTEKVKKQLNLWE
CHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCHHHHHHHCCCCC
>Mature Secondary Structure 
ATQRKIIHIDMDCFYAAIEMRENPALIGKPVAVGGSVEGRGVLTTCNYEARKFGLHSAM
CCCCEEEEEEHHHHHHHHHHCCCCCEECCCEEECCCCCCCEEEEECCCHHHHHCCHHCC
PTAQALKRCPNLILVPVNMPLYKAVSEQIHQIFRRYTDIVELLSLDEAYLDVTDCRQCSG
CHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCC
SATWIAQEIRDAIWNELHLTASAGIAPLKFLAKIASDQNKPNGQFVISPENMTAFIYDLP
CHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECC
LKKIPRVGKVTNEKLAQLGLHTCGDIQHSDKAFIYKTFGKFGQRLWEFSHAIDNRKIEAN
HHHCCCCCCHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RPRKSLAVENTLPTDIWHLAEAEQIVDELFKKLVFRLQRNWGERSLQEFKKLAIKLKFGD
CCHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCC
FTQTTLERTTDGLSRERFIELLQQVWQRTNRRSVRLIGLSVHYPTEKVKKQLNLWE
CHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA