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The map label for this gene is mrp [H]

Identifier: 126208474

GI number: 126208474

Start: 1162405

End: 1163502

Strand: Reverse

Name: mrp [H]

Synonym: APL_1000

Alternate gene names: 126208474

Gene position: 1163502-1162405 (Counterclockwise)

Preceding gene: 126208475

Following gene: 126208473

Centisome position: 51.15

GC content: 43.35

Gene sequence:

>1098_bases
ATGAATCAACTTAACGAACAGCAATTAAGTGAAATTAAATTCGTGTTACAAAATTTCACTCACCCTACTTTACAAAAGGA
CTTAATTGCATTGAATGTATTTAAAAAAGCAGAATTAGGTGCGGGAATTTTACGTTTAGAATTGACCATGCCATTTGCTT
GGAATAGCGGTTTTGCAGTATTAAAAACGGAAACAGAAGCGCAACTCAAACAAGTTACCGGTGCAAGTGAGGTAAAATGG
ATCCTAAATTACCAAATTGCAACCTTAAAACGTGCTAATAATCACCCGGCAGTAAACGGTGTAAAAAATATTATTGCAGT
AACCTCTGGGAAAGGTGGTGTAGGTAAATCGACTACTTCAGTGAACCTCGCATTAGCACTCAAAGCACAAGGCGCAAAAG
TGGGCATTTTGGATGCGGATATTTACGGTCCGTCCATTCCGCATATGTTAGGTGCGCAAGATCAGCGTCCGACGTCTCCG
GATAACAAACATATCACACCGATCGAAGTCTATGGTCTTCAATCGAACTCAATCGGCTATTTAATGGCGGATGATAATGC
GACCATTTGGCGTGGTCCGATGGCGAGTTCGGCATTAAGCCAGTTATTGAATGAAACATGGTGGACGGAATTGGATTACC
TTGTAATCGATATGCCGCCGGGTACAGGCGATATCCAACTTACTCTTTCGCAACAAATTCCGGTTACCGGTGCGGTAGTG
GTAACTACTCCGCAAGATATTGCGTTATTAGATGCGGTGAAAGGTATTTCAATGTTCCAAAAAGTGTCGGTACCGGTCTT
AGGTATCATTGAAAATATGAGCGTGCATATCTGCCAAAATTGCGGTCACCACGAAGATATTTTCGGCACCGGCGGTGCGG
AGAAAGTGGCGAAGAAATACGGCACCAAAGTATTAGGACAAATGCCGTTGCATATTCGCTTACGTCAAGATTTGGATGCC
GGCACACCGACCGTCGTTGCGGCACCGGAACACGAAACCAGCCAAGCATATATCGAATTAGCGGCAAAAGTCGCTTCAGA
ATTATACTGGCAAGGCTCGGTTATCCCGTCTGAAATTATGATTCGTGAAGTGAAATAA

Upstream 100 bases:

>100_bases
TGTTGCATTAGATCCCACCATTTTAGGTATTGATTTAAATAACGATAGCGAAGTAATTTATAGTAAACATTTATATCGAA
TGAAGCCCAAGGATTAATTG

Downstream 100 bases:

>100_bases
GCCTACATAACCACGGAATACCAGATAACACAGAAGGAAAACAAGCGGTAGAATTTGCAGAAAAAGTTGCAAATTCTACC
GCTTTTTTATTAGTACGATT

Product: putative ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MNQLNEQQLSEIKFVLQNFTHPTLQKDLIALNVFKKAELGAGILRLELTMPFAWNSGFAVLKTETEAQLKQVTGASEVKW
ILNYQIATLKRANNHPAVNGVKNIIAVTSGKGGVGKSTTSVNLALALKAQGAKVGILDADIYGPSIPHMLGAQDQRPTSP
DNKHITPIEVYGLQSNSIGYLMADDNATIWRGPMASSALSQLLNETWWTELDYLVIDMPPGTGDIQLTLSQQIPVTGAVV
VTTPQDIALLDAVKGISMFQKVSVPVLGIIENMSVHICQNCGHHEDIFGTGGAEKVAKKYGTKVLGQMPLHIRLRQDLDA
GTPTVVAAPEHETSQAYIELAAKVASELYWQGSVIPSEIMIREVK

Sequences:

>Translated_365_residues
MNQLNEQQLSEIKFVLQNFTHPTLQKDLIALNVFKKAELGAGILRLELTMPFAWNSGFAVLKTETEAQLKQVTGASEVKW
ILNYQIATLKRANNHPAVNGVKNIIAVTSGKGGVGKSTTSVNLALALKAQGAKVGILDADIYGPSIPHMLGAQDQRPTSP
DNKHITPIEVYGLQSNSIGYLMADDNATIWRGPMASSALSQLLNETWWTELDYLVIDMPPGTGDIQLTLSQQIPVTGAVV
VTTPQDIALLDAVKGISMFQKVSVPVLGIIENMSVHICQNCGHHEDIFGTGGAEKVAKKYGTKVLGQMPLHIRLRQDLDA
GTPTVVAAPEHETSQAYIELAAKVASELYWQGSVIPSEIMIREVK
>Mature_365_residues
MNQLNEQQLSEIKFVLQNFTHPTLQKDLIALNVFKKAELGAGILRLELTMPFAWNSGFAVLKTETEAQLKQVTGASEVKW
ILNYQIATLKRANNHPAVNGVKNIIAVTSGKGGVGKSTTSVNLALALKAQGAKVGILDADIYGPSIPHMLGAQDQRPTSP
DNKHITPIEVYGLQSNSIGYLMADDNATIWRGPMASSALSQLLNETWWTELDYLVIDMPPGTGDIQLTLSQQIPVTGAVV
VTTPQDIALLDAVKGISMFQKVSVPVLGIIENMSVHICQNCGHHEDIFGTGGAEKVAKKYGTKVLGQMPLHIRLRQDLDA
GTPTVVAAPEHETSQAYIELAAKVASELYWQGSVIPSEIMIREVK

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=282, Percent_Identity=47.8723404255319, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI6912540, Length=252, Percent_Identity=41.2698412698413, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI118572611, Length=252, Percent_Identity=37.3015873015873, Blast_Score=167, Evalue=1e-41,
Organism=Escherichia coli, GI87082045, Length=349, Percent_Identity=67.3352435530086, Blast_Score=484, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI25143050, Length=261, Percent_Identity=41.7624521072797, Blast_Score=188, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6322188, Length=274, Percent_Identity=36.1313868613139, Blast_Score=177, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6321347, Length=251, Percent_Identity=40.6374501992032, Blast_Score=174, Evalue=2e-44,
Organism=Drosophila melanogaster, GI221511043, Length=252, Percent_Identity=40.8730158730159, Blast_Score=205, Evalue=4e-53,
Organism=Drosophila melanogaster, GI24667611, Length=260, Percent_Identity=38.8461538461538, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI19921440, Length=236, Percent_Identity=38.135593220339, Blast_Score=136, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR000808 [H]

Pfam domain/function: PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 39538; Mature: 39538

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQLNEQQLSEIKFVLQNFTHPTLQKDLIALNVFKKAELGAGILRLELTMPFAWNSGFAV
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHEEHHHHHHCCCCCEEEEEEEECEEECCCEEE
LKTETEAQLKQVTGASEVKWILNYQIATLKRANNHPAVNGVKNIIAVTSGKGGVGKSTTS
EEECHHHHHHHHCCCCCEEEEEEEEEEEEEECCCCCCHHCCCEEEEEECCCCCCCCCCCE
VNLALALKAQGAKVGILDADIYGPSIPHMLGAQDQRPTSPDNKHITPIEVYGLQSNSIGY
EEEEEEEEECCCEEEEEECCCCCCCCCHHCCCCCCCCCCCCCCCCCEEEEEEECCCCEEE
LMADDNATIWRGPMASSALSQLLNETWWTELDYLVIDMPPGTGDIQLTLSQQIPVTGAVV
EEECCCCEEEECCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEECCCCCEEEEE
VTTPQDIALLDAVKGISMFQKVSVPVLGIIENMSVHICQNCGHHEDIFGTGGAEKVAKKY
EECCCCHHHHHHHHHHHHHHHHCCCCEEHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHHH
GTKVLGQMPLHIRLRQDLDAGTPTVVAAPEHETSQAYIELAAKVASELYWQGSVIPSEIM
CCHHHCCCCEEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHE
IREVK
EEECC
>Mature Secondary Structure
MNQLNEQQLSEIKFVLQNFTHPTLQKDLIALNVFKKAELGAGILRLELTMPFAWNSGFAV
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHEEHHHHHHCCCCCEEEEEEEECEEECCCEEE
LKTETEAQLKQVTGASEVKWILNYQIATLKRANNHPAVNGVKNIIAVTSGKGGVGKSTTS
EEECHHHHHHHHCCCCCEEEEEEEEEEEEEECCCCCCHHCCCEEEEEECCCCCCCCCCCE
VNLALALKAQGAKVGILDADIYGPSIPHMLGAQDQRPTSPDNKHITPIEVYGLQSNSIGY
EEEEEEEEECCCEEEEEECCCCCCCCCHHCCCCCCCCCCCCCCCCCEEEEEEECCCCEEE
LMADDNATIWRGPMASSALSQLLNETWWTELDYLVIDMPPGTGDIQLTLSQQIPVTGAVV
EEECCCCEEEECCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEEEECCCCCEEEEE
VTTPQDIALLDAVKGISMFQKVSVPVLGIIENMSVHICQNCGHHEDIFGTGGAEKVAKKY
EECCCCHHHHHHHHHHHHHHHHCCCCEEHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHHH
GTKVLGQMPLHIRLRQDLDAGTPTVVAAPEHETSQAYIELAAKVASELYWQGSVIPSEIM
CCHHHCCCCEEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHE
IREVK
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]