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The map label for this gene is galT [H]

Identifier: 126208468

GI number: 126208468

Start: 1149428

End: 1150477

Strand: Direct

Name: galT [H]

Synonym: APL_0994

Alternate gene names: 126208468

Gene position: 1149428-1150477 (Clockwise)

Preceding gene: 126208467

Following gene: 126208469

Centisome position: 50.54

GC content: 45.14

Gene sequence:

>1050_bases
ATGAGCCAACAATTTATCCTAAACGATCACCCTCATCGTCGTTTTAATCCGTTAAAAAATCAATGGATTTTAGTTTCTCC
GCATCGTGCGAAACGTCCGTGGCAAGGTCAGCAGGAAGAAACGGTTGCGGATAATAAACCGAGCTATGATCCGACTTGTT
ATCTCTGTCCGGGAAATAAACGCATTACCGGCGAACAAAATCCCGTTTATAGCAAACCTTTCGTCTTTAAAAACGATTTC
TCCGCACTACTGCCGGATACACCGGCGCCGGAAGCCGGTTCCGATCCGCTTTTCCAAATTTCACATACTCAAGGCGAAAG
CCGTGTAATTTGCTTCTCGCCTGATCACAGTAAAACCTTACCGCAACTTTCGGTGGCTGAAATTGAGCAAGTGGTACAAG
TCTGGCAAGAGCAAGCGAATGAGTTAAAAACACGTTATCAGTGGGTACAAATTTTTGAAAACAAAGGCTCGATGATGGGC
TGCTCTAATCCGCACCCGCACGGTCAAATTTGGGCAAGCAATTTCTTACCGAACGAAATTGCGATTGAAGACGAATGTCA
GGCAAATTACTTTGCTCAATACGGTCGTCCATTGCTTCTTGATTATGCCGAGCGTGAATTAACTAAAAAAGAACGTATCG
TCGTCGAAACCGAAGACTGGATTGCAGTGGTGCCTTACTGGGCTGGCTGGCCGTTTGAAACTTTACTGTTGCCGAAACAC
AAGCACTTTAAACGCATTACCGATTTAAACGAAGCGGAACGAGCGGATTTAGCTCTCGCACTTAAAAAGCTAACCACTCG
CTACGATAACTTATTTAATATCAGTTTCCCATATTCGATGGGCTTCCATTTCGCTCCGTTTAATGAAAGTGATAATCCGC
ATTGGCAACTTCACGCCCATTTCTATCCGCCGTTGTTACGTTCGGCAACCGTGCGTAAATTTATGGTCGGCTACGAGATG
ATGGCGGAAAGTCAGCGAGATCTGACACCGGAACAAGCGGCGGAAAGATTAAATGCTGTGAGCGACAGCGTTCACTATAA
AAATCAATAG

Upstream 100 bases:

>100_bases
AACAATCGGACTACGCTCACTTCTGTGATCATTATCACACACAAAAAAATCAATGTCGGCTATACTCCAATTCTAAAAAC
TCAAATGGAGAAGTTCTACA

Downstream 100 bases:

>100_bases
AAAGAAATAGCGAGAGAGAAAGATAGAATGAAACCACAACAGCTTGCGACACAAAAATTTAGCGAACATTACGGCTACTC
GGCAGCTCAAACCGTATTTG

Product: galactose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Gal-1-P uridylyltransferase; UDP-glucose--hexose-1-phosphate uridylyltransferase [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSQQFILNDHPHRRFNPLKNQWILVSPHRAKRPWQGQQEETVADNKPSYDPTCYLCPGNKRITGEQNPVYSKPFVFKNDF
SALLPDTPAPEAGSDPLFQISHTQGESRVICFSPDHSKTLPQLSVAEIEQVVQVWQEQANELKTRYQWVQIFENKGSMMG
CSNPHPHGQIWASNFLPNEIAIEDECQANYFAQYGRPLLLDYAERELTKKERIVVETEDWIAVVPYWAGWPFETLLLPKH
KHFKRITDLNEAERADLALALKKLTTRYDNLFNISFPYSMGFHFAPFNESDNPHWQLHAHFYPPLLRSATVRKFMVGYEM
MAESQRDLTPEQAAERLNAVSDSVHYKNQ

Sequences:

>Translated_349_residues
MSQQFILNDHPHRRFNPLKNQWILVSPHRAKRPWQGQQEETVADNKPSYDPTCYLCPGNKRITGEQNPVYSKPFVFKNDF
SALLPDTPAPEAGSDPLFQISHTQGESRVICFSPDHSKTLPQLSVAEIEQVVQVWQEQANELKTRYQWVQIFENKGSMMG
CSNPHPHGQIWASNFLPNEIAIEDECQANYFAQYGRPLLLDYAERELTKKERIVVETEDWIAVVPYWAGWPFETLLLPKH
KHFKRITDLNEAERADLALALKKLTTRYDNLFNISFPYSMGFHFAPFNESDNPHWQLHAHFYPPLLRSATVRKFMVGYEM
MAESQRDLTPEQAAERLNAVSDSVHYKNQ
>Mature_348_residues
SQQFILNDHPHRRFNPLKNQWILVSPHRAKRPWQGQQEETVADNKPSYDPTCYLCPGNKRITGEQNPVYSKPFVFKNDFS
ALLPDTPAPEAGSDPLFQISHTQGESRVICFSPDHSKTLPQLSVAEIEQVVQVWQEQANELKTRYQWVQIFENKGSMMGC
SNPHPHGQIWASNFLPNEIAIEDECQANYFAQYGRPLLLDYAERELTKKERIVVETEDWIAVVPYWAGWPFETLLLPKHK
HFKRITDLNEAERADLALALKKLTTRYDNLFNISFPYSMGFHFAPFNESDNPHWQLHAHFYPPLLRSATVRKFMVGYEMM
AESQRDLTPEQAAERLNAVSDSVHYKNQ

Specific function: Galactose metabolism; second step. [C]

COG id: COG1085

COG function: function code C; Galactose-1-phosphate uridylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family [H]

Homologues:

Organism=Homo sapiens, GI22165416, Length=345, Percent_Identity=56.5217391304348, Blast_Score=406, Evalue=1e-113,
Organism=Escherichia coli, GI1786973, Length=344, Percent_Identity=67.1511627906977, Blast_Score=493, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI17557105, Length=348, Percent_Identity=43.9655172413793, Blast_Score=303, Evalue=6e-83,
Organism=Saccharomyces cerevisiae, GI6319492, Length=362, Percent_Identity=48.0662983425414, Blast_Score=352, Evalue=5e-98,
Organism=Drosophila melanogaster, GI24582285, Length=347, Percent_Identity=55.3314121037464, Blast_Score=407, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001937
- InterPro:   IPR019779
- InterPro:   IPR005850
- InterPro:   IPR005849
- InterPro:   IPR011146
- InterPro:   IPR011151 [H]

Pfam domain/function: PF02744 GalP_UDP_tr_C; PF01087 GalP_UDP_transf [H]

EC number: =2.7.7.12 [H]

Molecular weight: Translated: 40532; Mature: 40401

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00117 GAL_P_UDP_TRANSF_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQFILNDHPHRRFNPLKNQWILVSPHRAKRPWQGQQEETVADNKPSYDPTCYLCPGNK
CCCCCCCCCCCCCCCCCCCCCEEEECCHHCCCCCCCCCCCHHCCCCCCCCCEEEEECCCC
RITGEQNPVYSKPFVFKNDFSALLPDTPAPEAGSDPLFQISHTQGESRVICFSPDHSKTL
EECCCCCCCCCCCEEEECCCHHHCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCC
PQLSVAEIEQVVQVWQEQANELKTRYQWVQIFENKGSMMGCSNPHPHGQIWASNFLPNEI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCEEEECCCCCCCE
AIEDECQANYFAQYGRPLLLDYAERELTKKERIVVETEDWIAVVPYWAGWPFETLLLPKH
EECCCHHHHHHHHCCCEEEEHHHHHHHCHHHEEEEEECCCEEEEECCCCCCCCEEECCCH
KHFKRITDLNEAERADLALALKKLTTRYDNLFNISFPYSMGFHFAPFNESDNPHWQLHAH
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCHHCCCEECCCCCCCCCCEEEEEE
FYPPLLRSATVRKFMVGYEMMAESQRDLTPEQAAERLNAVSDSVHYKNQ
ECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SQQFILNDHPHRRFNPLKNQWILVSPHRAKRPWQGQQEETVADNKPSYDPTCYLCPGNK
CCCCCCCCCCCCCCCCCCCCEEEECCHHCCCCCCCCCCCHHCCCCCCCCCEEEEECCCC
RITGEQNPVYSKPFVFKNDFSALLPDTPAPEAGSDPLFQISHTQGESRVICFSPDHSKTL
EECCCCCCCCCCCEEEECCCHHHCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCC
PQLSVAEIEQVVQVWQEQANELKTRYQWVQIFENKGSMMGCSNPHPHGQIWASNFLPNEI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCEEEECCCCCCCE
AIEDECQANYFAQYGRPLLLDYAERELTKKERIVVETEDWIAVVPYWAGWPFETLLLPKH
EECCCHHHHHHHHCCCEEEEHHHHHHHCHHHEEEEEECCCEEEEECCCCCCCCEEECCCH
KHFKRITDLNEAERADLALALKKLTTRYDNLFNISFPYSMGFHFAPFNESDNPHWQLHAH
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCHHCCCEECCCCCCCCCCEEEEEE
FYPPLLRSATVRKFMVGYEMMAESQRDLTPEQAAERLNAVSDSVHYKNQ
ECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1282642; 7542800 [H]