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The map label for this gene is arcB [H]

Identifier: 126208411

GI number: 126208411

Start: 1076113

End: 1077963

Strand: Reverse

Name: arcB [H]

Synonym: APL_0935

Alternate gene names: 126208411

Gene position: 1077963-1076113 (Counterclockwise)

Preceding gene: 126208412

Following gene: 126208408

Centisome position: 47.39

GC content: 42.09

Gene sequence:

>1851_bases
ATGAAGGCGATCAAACAATGCAGCCAGAGTTATGTAAATTGGGTATTGCGCTTGGGGAGAGGAAAGGCTGCCCTATTGGG
ATTCTTTGTATTGGCCAGCTGTGCCATTGTCGCACAAAGCCTTTTAACCTATCTGTTTACGGGCGGTATTTTAGCGCAGG
ATATTTTACGTTCGATTTCTTTCGGGTTGATTTCCGCCCCCTTTGTAATTTATTTCTTTAATCTGATTGTAGAGAAGCTG
GAAAAATCGAGAATCCAGCTTGAGCAAAGCGTGTACGATTTAGGTATTCTGCGCGAGCAAGATGCCTTTTTAAACGCAAC
CTTAGAAAAGAACAACCGTGATAAAAGCGTGTTAATGGCAACGATTAGCCATGAATTACGCACTCCGCTAAACGGTATTA
TCGGGTTAAGTCGAATCTTACTGGAAGGCGAATTGACTGATCAACAACGTGAATATCTAAAAACGATTAATATCAGTGCG
GTTTCGCTAGGGCATATCTTTAGCGATATTATCGATTTAGAAAAAATCGACAGCCGTCGAGTCGAGTTGTTTAGAAAAGA
AATCGAATTCTCGCAACTGATTAGCGATATTAGTAATTTCGGCAATTTAATGGCGGAACAAAATAAAATTAAATTTCATA
TCGATTACTCGGATGATTTACCGAATTTTATCTATGTGGATAATGCCCGCTTAAGCCAAATACTGTGGAATTTGGTCAGC
AATGCGGTCAAATTTACTCCGGCGGGCGGCGATATTTATTTAAGCGTGAAACGGATTGATAACGATCATTTCAGCTTTAG
CTTAAGAGATACCGGCATCGGTATTCCGAAACACGAACAACGCAAAGTGTTTGCAATGTTCTATCAAGCGGAAAATTCTC
AGGAAAGAAAAGCGCAAGGCAGCGGTATCGGTTTGGCGATTTCAAAACGTATCGCAAAATTAATGGGCGGTGATTTAACC
CTACGCAGTGAAATGGGCAAAGGTTCAACTTTTACCTTGACTATTCAGGCGGATCCGGTCGAAGCGAAAAAATCGGTGAA
AATCAACGCGCACGCGTTAAAAGTCTTATTGGTGGAAGATATTGAAGTGAATGTGGTTGTCGCGCGTGCCATGTTAGAGA
AATTCGGCTGTGATGTGGATGTCGCAATGACCGGCGCACAAGCGTTTGAGTTATTTGAACGGAACAGCTACGACTTGATT
TTATTGGATATTCAATTACCGGATATGACCGGCTTTGATATTGCGCAACGATTACGCGAACGTTATGAAAACGAAGAAGT
GGATTATTTACCATTATTAGTGGCATTAACCGCCAATATTATGCAAACCAAAGAGGAATATCAGCAACAGGGTATGGACG
ACGTGTTGCGTAAACCGCTTTCGTTGGAAGCATTATCCGAATGCCTAAATCATTATTTTAACAGTGATTTTTCGGAAAAA
ACTGCTGAAATTCCACCGCTTGTTGAAACGGAAGAAACGCTCAACCTACCGTATGATCGTAAAATTTTATCGGAATTTAT
TGAGGTAATGGGGGCGAAAGCGGTATTGGCGAACTTTGCATTATTCGCCAAATTAATGCCGGAGTATTTGGCTAATCTAC
AACATTATCTGACCGAATGGCAGGCAACCGATTCGCCGGAAATGCGCAAATGTACGGCGGATGAAGCGCATAAAATCAAA
GGCGCATTGGCTTCGGTCAGCTTGAAACGCTTACAAGAAGTCGCACAACTTGCGCAGAGCGATAACGGAGAAGTGTGGGA
ACAGCATATCGCACAATGGGTGTTCCAAATCGCTCAACAGTGGCAAGCGGATTTAGCATTAGCGGAAAATTGGGTAAAAG
AAAATTACTAA

Upstream 100 bases:

>100_bases
TTTGAATCAATAATCAAAACTATTCAGATACACAGTTTAAGCTATAATAAATCCTTTCTATTTTTAAACGATAGAAAGGA
TTTTCTTTTAAGGGGGAACA

Downstream 100 bases:

>100_bases
TCGAAAGGGGATAACGTCTTTAGGCTTTATCCCATTTTTTATGTTTCGGATTGACGAATTCAATCCCTTTATCTTTAAAA
TGAATTCCTTCGAGTGCCAA

Product: aerobic respiration control sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 616

Protein sequence:

>616_residues
MKAIKQCSQSYVNWVLRLGRGKAALLGFFVLASCAIVAQSLLTYLFTGGILAQDILRSISFGLISAPFVIYFFNLIVEKL
EKSRIQLEQSVYDLGILREQDAFLNATLEKNNRDKSVLMATISHELRTPLNGIIGLSRILLEGELTDQQREYLKTINISA
VSLGHIFSDIIDLEKIDSRRVELFRKEIEFSQLISDISNFGNLMAEQNKIKFHIDYSDDLPNFIYVDNARLSQILWNLVS
NAVKFTPAGGDIYLSVKRIDNDHFSFSLRDTGIGIPKHEQRKVFAMFYQAENSQERKAQGSGIGLAISKRIAKLMGGDLT
LRSEMGKGSTFTLTIQADPVEAKKSVKINAHALKVLLVEDIEVNVVVARAMLEKFGCDVDVAMTGAQAFELFERNSYDLI
LLDIQLPDMTGFDIAQRLRERYENEEVDYLPLLVALTANIMQTKEEYQQQGMDDVLRKPLSLEALSECLNHYFNSDFSEK
TAEIPPLVETEETLNLPYDRKILSEFIEVMGAKAVLANFALFAKLMPEYLANLQHYLTEWQATDSPEMRKCTADEAHKIK
GALASVSLKRLQEVAQLAQSDNGEVWEQHIAQWVFQIAQQWQADLALAENWVKENY

Sequences:

>Translated_616_residues
MKAIKQCSQSYVNWVLRLGRGKAALLGFFVLASCAIVAQSLLTYLFTGGILAQDILRSISFGLISAPFVIYFFNLIVEKL
EKSRIQLEQSVYDLGILREQDAFLNATLEKNNRDKSVLMATISHELRTPLNGIIGLSRILLEGELTDQQREYLKTINISA
VSLGHIFSDIIDLEKIDSRRVELFRKEIEFSQLISDISNFGNLMAEQNKIKFHIDYSDDLPNFIYVDNARLSQILWNLVS
NAVKFTPAGGDIYLSVKRIDNDHFSFSLRDTGIGIPKHEQRKVFAMFYQAENSQERKAQGSGIGLAISKRIAKLMGGDLT
LRSEMGKGSTFTLTIQADPVEAKKSVKINAHALKVLLVEDIEVNVVVARAMLEKFGCDVDVAMTGAQAFELFERNSYDLI
LLDIQLPDMTGFDIAQRLRERYENEEVDYLPLLVALTANIMQTKEEYQQQGMDDVLRKPLSLEALSECLNHYFNSDFSEK
TAEIPPLVETEETLNLPYDRKILSEFIEVMGAKAVLANFALFAKLMPEYLANLQHYLTEWQATDSPEMRKCTADEAHKIK
GALASVSLKRLQEVAQLAQSDNGEVWEQHIAQWVFQIAQQWQADLALAENWVKENY
>Mature_616_residues
MKAIKQCSQSYVNWVLRLGRGKAALLGFFVLASCAIVAQSLLTYLFTGGILAQDILRSISFGLISAPFVIYFFNLIVEKL
EKSRIQLEQSVYDLGILREQDAFLNATLEKNNRDKSVLMATISHELRTPLNGIIGLSRILLEGELTDQQREYLKTINISA
VSLGHIFSDIIDLEKIDSRRVELFRKEIEFSQLISDISNFGNLMAEQNKIKFHIDYSDDLPNFIYVDNARLSQILWNLVS
NAVKFTPAGGDIYLSVKRIDNDHFSFSLRDTGIGIPKHEQRKVFAMFYQAENSQERKAQGSGIGLAISKRIAKLMGGDLT
LRSEMGKGSTFTLTIQADPVEAKKSVKINAHALKVLLVEDIEVNVVVARAMLEKFGCDVDVAMTGAQAFELFERNSYDLI
LLDIQLPDMTGFDIAQRLRERYENEEVDYLPLLVALTANIMQTKEEYQQQGMDDVLRKPLSLEALSECLNHYFNSDFSEK
TAEIPPLVETEETLNLPYDRKILSEFIEVMGAKAVLANFALFAKLMPEYLANLQHYLTEWQATDSPEMRKCTADEAHKIK
GALASVSLKRLQEVAQLAQSDNGEVWEQHIAQWVFQIAQQWQADLALAENWVKENY

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=522, Percent_Identity=46.9348659003831, Blast_Score=466, Evalue=1e-132,
Organism=Escherichia coli, GI1788713, Length=485, Percent_Identity=29.8969072164948, Blast_Score=172, Evalue=6e-44,
Organism=Escherichia coli, GI1789149, Length=411, Percent_Identity=31.8734793187348, Blast_Score=168, Evalue=8e-43,
Organism=Escherichia coli, GI87081816, Length=376, Percent_Identity=28.9893617021277, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI145693157, Length=254, Percent_Identity=36.2204724409449, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1790861, Length=202, Percent_Identity=28.2178217821782, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=28.3783783783784, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786600, Length=217, Percent_Identity=27.6497695852535, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1786783, Length=258, Percent_Identity=26.7441860465116, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=28.110599078341, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786912, Length=225, Percent_Identity=25.3333333333333, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1788279, Length=217, Percent_Identity=26.2672811059908, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=27.1551724137931, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87082128, Length=218, Percent_Identity=25.6880733944954, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=200, Percent_Identity=26.5, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322000, Length=174, Percent_Identity=30.4597701149425, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322044, Length=148, Percent_Identity=34.4594594594595, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69740; Mature: 69740

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIKQCSQSYVNWVLRLGRGKAALLGFFVLASCAIVAQSLLTYLFTGGILAQDILRSIS
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
FGLISAPFVIYFFNLIVEKLEKSRIQLEQSVYDLGILREQDAFLNATLEKNNRDKSVLMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHH
TISHELRTPLNGIIGLSRILLEGELTDQQREYLKTINISAVSLGHIFSDIIDLEKIDSRR
HHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
VELFRKEIEFSQLISDISNFGNLMAEQNKIKFHIDYSDDLPNFIYVDNARLSQILWNLVS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEECCHHHHHHHHHHHH
NAVKFTPAGGDIYLSVKRIDNDHFSFSLRDTGIGIPKHEQRKVFAMFYQAENSQERKAQG
CCEEECCCCCEEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHCC
SGIGLAISKRIAKLMGGDLTLRSEMGKGSTFTLTIQADPVEAKKSVKINAHALKVLLVED
CCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEECCCCCCCCEEEEHHHEEEEEEEC
IEVNVVVARAMLEKFGCDVDVAMTGAQAFELFERNSYDLILLDIQLPDMTGFDIAQRLRE
CCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHH
RYENEEVDYLPLLVALTANIMQTKEEYQQQGMDDVLRKPLSLEALSECLNHYFNSDFSEK
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHCCCCCHH
TAEIPPLVETEETLNLPYDRKILSEFIEVMGAKAVLANFALFAKLMPEYLANLQHYLTEW
HCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QATDSPEMRKCTADEAHKIKGALASVSLKRLQEVAQLAQSDNGEVWEQHIAQWVFQIAQQ
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
WQADLALAENWVKENY
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKAIKQCSQSYVNWVLRLGRGKAALLGFFVLASCAIVAQSLLTYLFTGGILAQDILRSIS
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
FGLISAPFVIYFFNLIVEKLEKSRIQLEQSVYDLGILREQDAFLNATLEKNNRDKSVLMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHH
TISHELRTPLNGIIGLSRILLEGELTDQQREYLKTINISAVSLGHIFSDIIDLEKIDSRR
HHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
VELFRKEIEFSQLISDISNFGNLMAEQNKIKFHIDYSDDLPNFIYVDNARLSQILWNLVS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEECCHHHHHHHHHHHH
NAVKFTPAGGDIYLSVKRIDNDHFSFSLRDTGIGIPKHEQRKVFAMFYQAENSQERKAQG
CCEEECCCCCEEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHCC
SGIGLAISKRIAKLMGGDLTLRSEMGKGSTFTLTIQADPVEAKKSVKINAHALKVLLVED
CCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEECCCCCCCCEEEEHHHEEEEEEEC
IEVNVVVARAMLEKFGCDVDVAMTGAQAFELFERNSYDLILLDIQLPDMTGFDIAQRLRE
CCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHH
RYENEEVDYLPLLVALTANIMQTKEEYQQQGMDDVLRKPLSLEALSECLNHYFNSDFSEK
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHCCCCCHH
TAEIPPLVETEETLNLPYDRKILSEFIEVMGAKAVLANFALFAKLMPEYLANLQHYLTEW
HCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QATDSPEMRKCTADEAHKIKGALASVSLKRLQEVAQLAQSDNGEVWEQHIAQWVFQIAQQ
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
WQADLALAENWVKENY
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]