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The map label for this gene is fdhE

Identifier: 126208372

GI number: 126208372

Start: 1038255

End: 1039172

Strand: Direct

Name: fdhE

Synonym: APL_0896

Alternate gene names: 126208372

Gene position: 1038255-1039172 (Clockwise)

Preceding gene: 126208371

Following gene: 126208373

Centisome position: 45.65

GC content: 43.36

Gene sequence:

>918_bases
ATGAGTATCCGAATTTTACCCGAAAACGAAATTAAACAAGCTGCAAGCTCGTTTCAAAATCCGCCTTTATTATTCGCTAA
TCCAAAGAACCTATATTTTCGTCGCGCCAAACGATTACGCCAATTGGCTGAAAATAATCCGTTCGGCGATTACTTGGAAT
TTGCGGCGAATCTTTCCGAAGTACAGTTAGATTTATTGGAAAATCATCCCATTGCAAATTATGCGGAAAAATTAACCGCT
TGCATTGAAGAATCAAACGGACAAAAACCGCTGAATGCCAAAACCTTTAAGCGTTCAAGCGAATGGCGCGAATTGCTTTT
GTTATTAACTGAGAAATTTAAACCCTATGCTAACGACACGATGTTGGCAACGATTGAGTTATTAGAGAAATCATCCACTT
CCGAACTGGAAGCGTTAGCCGACGATTTACTCAATGAGCGTTATGAAGCGGTCGGTGCGGATAAAGCGGTATTCTTATGG
GCGGCGTTATCGCTTTATTGGACGCAATTAGCCCAACAGCTACCGCGTAATACGCAAACGGAAGTCGGCGAACGTCATAC
TTGTCCGGTTTGTGACTCTGCACCTATCGTAAGCGTGGTACATTTTGGCGATACGCAAGGCTTACGCTATTTACACTGCT
CTCTATGCGAAAGCGAATGGAATATGGTGCGTTCGCAATGCTCCGTTTGCGATCAAAGCGGTAAATTGGATTATTGGAGT
ATTGATAGTGTAGATGCGCCAGTAAAAGCTGAAAGTTGCGGCGATTGCGAAAGTTATTTGAAAGTGCTTTATCAAGAAAA
AGATCCGCACGTAGAACCGGTTGCGGACGATTTAGGCACGCTATTCTTAGATGCGGAAATGGAACAGAAAGGCTTTGCGC
GCAGCGGCCTAAATCCGTTCTTATTCCAAGTTGAATAA

Upstream 100 bases:

>100_bases
AAGATACAAGTGCGGTAAACTTACCGCACTTTATTTTTAAATACTTGCTAAATTTCTTTTGACTAAGGGAATTTAGCAAG
ATTTAACGAGAGAACATAAT

Downstream 100 bases:

>100_bases
TCCCTTCCTTTACTAATAAGCGGTCAAATTTGACCGCTTATTTTCATCTAAACAGGCTAAACTCTAAGAAATCATAAGGC
ATTCTTTCAATACAGATCAC

Product: formate dehydrogenase accessory protein FdhE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSIRILPENEIKQAASSFQNPPLLFANPKNLYFRRAKRLRQLAENNPFGDYLEFAANLSEVQLDLLENHPIANYAEKLTA
CIEESNGQKPLNAKTFKRSSEWRELLLLLTEKFKPYANDTMLATIELLEKSSTSELEALADDLLNERYEAVGADKAVFLW
AALSLYWTQLAQQLPRNTQTEVGERHTCPVCDSAPIVSVVHFGDTQGLRYLHCSLCESEWNMVRSQCSVCDQSGKLDYWS
IDSVDAPVKAESCGDCESYLKVLYQEKDPHVEPVADDLGTLFLDAEMEQKGFARSGLNPFLFQVE

Sequences:

>Translated_305_residues
MSIRILPENEIKQAASSFQNPPLLFANPKNLYFRRAKRLRQLAENNPFGDYLEFAANLSEVQLDLLENHPIANYAEKLTA
CIEESNGQKPLNAKTFKRSSEWRELLLLLTEKFKPYANDTMLATIELLEKSSTSELEALADDLLNERYEAVGADKAVFLW
AALSLYWTQLAQQLPRNTQTEVGERHTCPVCDSAPIVSVVHFGDTQGLRYLHCSLCESEWNMVRSQCSVCDQSGKLDYWS
IDSVDAPVKAESCGDCESYLKVLYQEKDPHVEPVADDLGTLFLDAEMEQKGFARSGLNPFLFQVE
>Mature_304_residues
SIRILPENEIKQAASSFQNPPLLFANPKNLYFRRAKRLRQLAENNPFGDYLEFAANLSEVQLDLLENHPIANYAEKLTAC
IEESNGQKPLNAKTFKRSSEWRELLLLLTEKFKPYANDTMLATIELLEKSSTSELEALADDLLNERYEAVGADKAVFLWA
ALSLYWTQLAQQLPRNTQTEVGERHTCPVCDSAPIVSVVHFGDTQGLRYLHCSLCESEWNMVRSQCSVCDQSGKLDYWSI
DSVDAPVKAESCGDCESYLKVLYQEKDPHVEPVADDLGTLFLDAEMEQKGFARSGLNPFLFQVE

Specific function: Necessary for formate dehydrogenase activity

COG id: COG3058

COG function: function code O; Uncharacterized protein involved in formate dehydrogenase formation

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fdhE family

Homologues:

Organism=Escherichia coli, GI1790324, Length=310, Percent_Identity=53.5483870967742, Blast_Score=333, Evalue=1e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FDHE_ACTP2 (A3N0Q6)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053597.1
- ProteinModelPortal:   A3N0Q6
- SMR:   A3N0Q6
- STRING:   A3N0Q6
- GeneID:   4849150
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0896
- eggNOG:   COG3058
- HOGENOM:   HBG678838
- OMA:   LCACEWH
- PhylomeDB:   A3N0Q6
- ProtClustDB:   PRK03564
- BioCyc:   APLE416269:APL_0896-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00611
- InterPro:   IPR006452
- PIRSF:   PIRSF018296
- TIGRFAMs:   TIGR01562

Pfam domain/function: PF04216 FdhE

EC number: NA

Molecular weight: Translated: 34513; Mature: 34382

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRILPENEIKQAASSFQNPPLLFANPKNLYFRRAKRLRQLAENNPFGDYLEFAANLSE
CEEEECCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHH
VQLDLLENHPIANYAEKLTACIEESNGQKPLNAKTFKRSSEWRELLLLLTEKFKPYANDT
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH
MLATIELLEKSSTSELEALADDLLNERYEAVGADKAVFLWAALSLYWTQLAQQLPRNTQT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
EVGERHTCPVCDSAPIVSVVHFGDTQGLRYLHCSLCESEWNMVRSQCSVCDQSGKLDYWS
HCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
IDSVDAPVKAESCGDCESYLKVLYQEKDPHVEPVADDLGTLFLDAEMEQKGFARSGLNPF
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHCHHHCCCCCE
LFQVE
EEEEC
>Mature Secondary Structure 
SIRILPENEIKQAASSFQNPPLLFANPKNLYFRRAKRLRQLAENNPFGDYLEFAANLSE
EEEECCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHH
VQLDLLENHPIANYAEKLTACIEESNGQKPLNAKTFKRSSEWRELLLLLTEKFKPYANDT
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH
MLATIELLEKSSTSELEALADDLLNERYEAVGADKAVFLWAALSLYWTQLAQQLPRNTQT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
EVGERHTCPVCDSAPIVSVVHFGDTQGLRYLHCSLCESEWNMVRSQCSVCDQSGKLDYWS
HCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
IDSVDAPVKAESCGDCESYLKVLYQEKDPHVEPVADDLGTLFLDAEMEQKGFARSGLNPF
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHCHHHCCCCCE
LFQVE
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA