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The map label for this gene is radA [H]

Identifier: 126208357

GI number: 126208357

Start: 1021263

End: 1022642

Strand: Direct

Name: radA [H]

Synonym: APL_0881

Alternate gene names: 126208357

Gene position: 1021263-1022642 (Clockwise)

Preceding gene: 126208350

Following gene: 126208360

Centisome position: 44.9

GC content: 48.48

Gene sequence:

>1380_bases
ATGGCTAAAGCACCAAAAACAGCTTATGTATGTAATGATTGCGGCGCGGAATATTCTCGTTGGATGGGGCAATGCAAAGA
ATGTAAGTCTTGGAATACCGTGAGTGAAATTAGACTTATCTCGAGTAAAGAAGCAACAAAAAGCGACCGCTTCAGCGGAT
ATGCCGGCGAAACCTCCGGTAAAGTTCAAACTTTATCCGAAATCAGCTTACAAGAAGTGCCTCGTTTTAGCAGCGGCTTT
AATGAATTGGATCGCGTACTGGGCGGCGGCGTCGTGCCGGGTTCGGCAATTTTAATCGGCGGCCATCCCGGTGCCGGTAA
ATCCACTCTGCTTTTACAAGTAATGTGCGGTTTGTCTAAAGATTTGCCGACCCTTTACGTGACCGGTGAAGAATCCCTAC
AACAAGTGGCGATGCGAGCGAATCGTTTAGGCTTACCGACCGACAATCTCAAGATGCTTTCAGAAACTTCGGTCGAGCAT
ATTTGTAATATCGCCGACCAAGAAAAGCCGAAAATTATGGTAATCGACTCAATTCAGGTCATGCACCTTGCCGATATTCA
ATCTTCTCCCGGTAGCGTTTCGCAAGTGCGGGAATGCGCTTCGTTTCTGACTCGCTATGCAAAAACCCGCCAAGTAGCGA
TTATTATGGTCGGACACGTCACCAAAGACGGGACACTTGCCGGCCCGAAAGTGTTGGAACACTGTATTGACGCCTCAATT
TTACTGGAAGGCGAATCGGACTCTCGATTCCGTACCTTACGCAGCCAGAAAAACCGTTTCGGTGCGGTCAATGAATTGGG
CGTATTTGCCATGACCGAACAAGGCTTACGAGAAGTAAAAAACCCTTCCGCGATTTTCCTCAGCCGTAGCGATGAACAAA
CGCCGGGCAGTTCCGTGATGGTGCTTTGGGAAGGAACCCGTCCGTTATTAGTCGAAATTCAAGCGTTGGTTGATCATTCG
ATGTTGGCTAATCCTCGCCGTGTCGCCGTAGGTTTGGATCACAACCGTTTATCGCTCTTACTTGCGGTGTTACATCGCCA
CGGCGGTTTGCAAATGTCAGATCAAGATGTGTTCGTCAATGTGGTCGGCGGGGTAAAAGTGACCGAGACCAGTGCCGATC
TCGCCCTAATTTTGGCGTTAATTTCCAGTTTTAGAAATCGTGCGTTACCGCAAGATTTGGTCGTATTCGGCGAGGTGGGA
TTAGCCGGAGAAATTCGTCCGGTACCGAGCGGTCAAGAACGTATCAGCGAAGCGGCGAAGCACGGTTTTAAACGTGCGAT
TATTCCTCACGGCAACGCACCTAAAAAACCGATTAAAGGTATGGAAGTCTTTACCGTTAAGAAACTAAGCGACGCACTAG
ATATTCTCGGCAATCTCTAA

Upstream 100 bases:

>100_bases
CTTCTGCGATCCGTATCGCAAAAACAGAATATTTATAGCTGTTTATTTACTCAGTATCTTTTGCTATGATTATATCGTTT
TAACAAATTCAGAGGTCAAA

Downstream 100 bases:

>100_bases
TACAAAAACAGACCGTGATAAGCGGTCTGTTTTAGTTAAAATCTTACGAATTGATTTCTTGTGGTTTATGCCGATTTTTA
AAGACAAAATAAAAATTCAG

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MAKAPKTAYVCNDCGAEYSRWMGQCKECKSWNTVSEIRLISSKEATKSDRFSGYAGETSGKVQTLSEISLQEVPRFSSGF
NELDRVLGGGVVPGSAILIGGHPGAGKSTLLLQVMCGLSKDLPTLYVTGEESLQQVAMRANRLGLPTDNLKMLSETSVEH
ICNIADQEKPKIMVIDSIQVMHLADIQSSPGSVSQVRECASFLTRYAKTRQVAIIMVGHVTKDGTLAGPKVLEHCIDASI
LLEGESDSRFRTLRSQKNRFGAVNELGVFAMTEQGLREVKNPSAIFLSRSDEQTPGSSVMVLWEGTRPLLVEIQALVDHS
MLANPRRVAVGLDHNRLSLLLAVLHRHGGLQMSDQDVFVNVVGGVKVTETSADLALILALISSFRNRALPQDLVVFGEVG
LAGEIRPVPSGQERISEAAKHGFKRAIIPHGNAPKKPIKGMEVFTVKKLSDALDILGNL

Sequences:

>Translated_459_residues
MAKAPKTAYVCNDCGAEYSRWMGQCKECKSWNTVSEIRLISSKEATKSDRFSGYAGETSGKVQTLSEISLQEVPRFSSGF
NELDRVLGGGVVPGSAILIGGHPGAGKSTLLLQVMCGLSKDLPTLYVTGEESLQQVAMRANRLGLPTDNLKMLSETSVEH
ICNIADQEKPKIMVIDSIQVMHLADIQSSPGSVSQVRECASFLTRYAKTRQVAIIMVGHVTKDGTLAGPKVLEHCIDASI
LLEGESDSRFRTLRSQKNRFGAVNELGVFAMTEQGLREVKNPSAIFLSRSDEQTPGSSVMVLWEGTRPLLVEIQALVDHS
MLANPRRVAVGLDHNRLSLLLAVLHRHGGLQMSDQDVFVNVVGGVKVTETSADLALILALISSFRNRALPQDLVVFGEVG
LAGEIRPVPSGQERISEAAKHGFKRAIIPHGNAPKKPIKGMEVFTVKKLSDALDILGNL
>Mature_458_residues
AKAPKTAYVCNDCGAEYSRWMGQCKECKSWNTVSEIRLISSKEATKSDRFSGYAGETSGKVQTLSEISLQEVPRFSSGFN
ELDRVLGGGVVPGSAILIGGHPGAGKSTLLLQVMCGLSKDLPTLYVTGEESLQQVAMRANRLGLPTDNLKMLSETSVEHI
CNIADQEKPKIMVIDSIQVMHLADIQSSPGSVSQVRECASFLTRYAKTRQVAIIMVGHVTKDGTLAGPKVLEHCIDASIL
LEGESDSRFRTLRSQKNRFGAVNELGVFAMTEQGLREVKNPSAIFLSRSDEQTPGSSVMVLWEGTRPLLVEIQALVDHSM
LANPRRVAVGLDHNRLSLLLAVLHRHGGLQMSDQDVFVNVVGGVKVTETSADLALILALISSFRNRALPQDLVVFGEVGL
AGEIRPVPSGQERISEAAKHGFKRAIIPHGNAPKKPIKGMEVFTVKKLSDALDILGNL

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=460, Percent_Identity=77.8260869565217, Blast_Score=760, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 49679; Mature: 49548

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAPKTAYVCNDCGAEYSRWMGQCKECKSWNTVSEIRLISSKEATKSDRFSGYAGETSG
CCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
KVQTLSEISLQEVPRFSSGFNELDRVLGGGVVPGSAILIGGHPGAGKSTLLLQVMCGLSK
CHHHHHHHHHHHCCCHHCCHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCC
DLPTLYVTGEESLQQVAMRANRLGLPTDNLKMLSETSVEHICNIADQEKPKIMVIDSIQV
CCCEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECEEE
MHLADIQSSPGSVSQVRECASFLTRYAKTRQVAIIMVGHVTKDGTLAGPKVLEHCIDASI
EEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCHHHHHHHCCCEE
LLEGESDSRFRTLRSQKNRFGAVNELGVFAMTEQGLREVKNPSAIFLSRSDEQTPGSSVM
EEECCCCHHHHHHHHHHHHCCCHHHCCHHEECHHHHHHHCCCCEEEEECCCCCCCCCEEE
VLWEGTRPLLVEIQALVDHSMLANPRRVAVGLDHNRLSLLLAVLHRHGGLQMSDQDVFVN
EEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEE
VVGGVKVTETSADLALILALISSFRNRALPQDLVVFGEVGLAGEIRPVPSGQERISEAAK
EECCEEEEECCHHHHHHHHHHHHHHHCCCCCHHEEEECCCCCCCCCCCCCHHHHHHHHHH
HGFKRAIIPHGNAPKKPIKGMEVFTVKKLSDALDILGNL
CCCCEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKAPKTAYVCNDCGAEYSRWMGQCKECKSWNTVSEIRLISSKEATKSDRFSGYAGETSG
CCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCC
KVQTLSEISLQEVPRFSSGFNELDRVLGGGVVPGSAILIGGHPGAGKSTLLLQVMCGLSK
CHHHHHHHHHHHCCCHHCCHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCC
DLPTLYVTGEESLQQVAMRANRLGLPTDNLKMLSETSVEHICNIADQEKPKIMVIDSIQV
CCCEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECEEE
MHLADIQSSPGSVSQVRECASFLTRYAKTRQVAIIMVGHVTKDGTLAGPKVLEHCIDASI
EEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCHHHHHHHCCCEE
LLEGESDSRFRTLRSQKNRFGAVNELGVFAMTEQGLREVKNPSAIFLSRSDEQTPGSSVM
EEECCCCHHHHHHHHHHHHCCCHHHCCHHEECHHHHHHHCCCCEEEEECCCCCCCCCEEE
VLWEGTRPLLVEIQALVDHSMLANPRRVAVGLDHNRLSLLLAVLHRHGGLQMSDQDVFVN
EEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEE
VVGGVKVTETSADLALILALISSFRNRALPQDLVVFGEVGLAGEIRPVPSGQERISEAAK
EECCEEEEECCHHHHHHHHHHHHHHHCCCCCHHEEEECCCCCCCCCCCCCHHHHHHHHHH
HGFKRAIIPHGNAPKKPIKGMEVFTVKKLSDALDILGNL
CCCCEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]