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The map label for this gene is xseA [H]

Identifier: 126208293

GI number: 126208293

Start: 943691

End: 945151

Strand: Direct

Name: xseA [H]

Synonym: APL_0817

Alternate gene names: 126208293

Gene position: 943691-945151 (Clockwise)

Preceding gene: 126208291

Following gene: 126208295

Centisome position: 41.49

GC content: 42.85

Gene sequence:

>1461_bases
ATGAATAATATTCTTACCATCACGCAACTTAACTATTCGGTACGCAATCTGCTTGAAACGGAATTAGGGCAAGTTTGGCT
TACCGGTGAAATTTCCAATTTTAGCCAACCCGTTTCCGGACATTGGTATCTCACCCTTAAAGACGAAAACGCCCAAGTGC
GTGGTGCGATGTTCAGAATGAAAAACCAACGAGTCACTTTCCGTCCGCAAAACGGTATGCAAGTGCTGGTACGTGCGAGT
GTCAGTTTATATGAGCCGCGTGGCGACTATCAAATCATTATTGAAAGTATGCAGCCTGCCGGTGACGGCTTATTACAGCA
ACAGTTTGAACAGCTGAAAATGAAACTGGCCGCCGAAGGACTTTTTGCACAAGAGAAGAAAAAAGCCATTCCGCCTTTTG
CTAAGCGAGTCGGTATTATTACCTCTTCAAGCGGTGCGGCATTACAGGATATTCTGAATATTTTAAAACGCCGTGACCCG
AGTCTGGCGATCATTATTTATCCGACTCTAGTACAAGGTAAAGAAGCGACGCAAGATATTGTAAATACGATTGATTTAGC
CAATCGCCGCCGAGAATGCGATGTGTTAATTGTCGGTCGTGGCGGCGGTTCGCTAGAGGACTTATGGTGTTTTAATGAAG
AAGCTGTCGCTCATGCCATTTTCCGTTCGGATATTCCAATTATCAGTGCAGTAGGTCACGAAACCGATGTGACGATTGCC
GATTTTGTTGCAGATTTAAGAGCGCCGACCCCCTCTGCCGCAGCAGAATTGGTTAGCCGAGATCAACAAGAGTTAGTACG
TCAGTTACAACATCAATTTGACAAATTAAGCCTTGCTTTTGACCGCTTGTGGACGGAGAAACAAACATATTTCGAACGTT
TAAAACTACGTTTAAATGCGCAGCATCCTGCTCGTCAGGTTCAAATGCAGCAGCAACGATTAGCTCAATTTAGCTATCGC
TTAGAAAATGCGATACATAAAACTTATTTAACCGAGAAACAGAAACTCGAACAATTATTGCTACGCTTAACCAATCAGCA
TCCGCAACGTCAGTTACAACAGCAACAAATGCAATTAAAGCAAGCAGAATATCGTCTGGCGCAAGCGATAGAACAAACCT
TAATCCGCAAACAAAACCAGTGGAAACATATTGTCGAACAAGTGAAACGTAATCCGTTGCCATACTGTGTAGAAAAGAAA
AATCAACAGTATGCGCAATTAGCACAACGACTTCAGTTTGCGATTGAAAAGAAATTAACCAAAGAACAGCAAGCATTTCA
GGAACTTTGCACGAGAATAGACGGTTTAAGTCCGCTAAAAATTCTAGCGAGAGGCTATTCCGTGACACAAACCTCTAAAG
GCGAAATCTTGCGTTCAACCGAAAATCTTAAGGTAGGCACGCAAATCACCACTAAACTTTCGCAAGGCGAAATCGTGAGC
GAAATCATTAAAATCAATTGA

Upstream 100 bases:

>100_bases
GGCTTTTTTGTATTTGCAAAAAATAACTGAAAATTTACCGCTTGCACCTTATCTTCCTTTACCAGTAAACTTTCCTAAAA
TCTTCGGCAACTTTCTAGAT

Downstream 100 bases:

>100_bases
TTAAAATACAAACAAACCTAATCAATTTGCTTTTTTCTTTTTCAAATCAAGAAGTTAATCATTTATACTCTATATTGTTC
ACGAAGTTATCCACAATTAA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MNNILTITQLNYSVRNLLETELGQVWLTGEISNFSQPVSGHWYLTLKDENAQVRGAMFRMKNQRVTFRPQNGMQVLVRAS
VSLYEPRGDYQIIIESMQPAGDGLLQQQFEQLKMKLAAEGLFAQEKKKAIPPFAKRVGIITSSSGAALQDILNILKRRDP
SLAIIIYPTLVQGKEATQDIVNTIDLANRRRECDVLIVGRGGGSLEDLWCFNEEAVAHAIFRSDIPIISAVGHETDVTIA
DFVADLRAPTPSAAAELVSRDQQELVRQLQHQFDKLSLAFDRLWTEKQTYFERLKLRLNAQHPARQVQMQQQRLAQFSYR
LENAIHKTYLTEKQKLEQLLLRLTNQHPQRQLQQQQMQLKQAEYRLAQAIEQTLIRKQNQWKHIVEQVKRNPLPYCVEKK
NQQYAQLAQRLQFAIEKKLTKEQQAFQELCTRIDGLSPLKILARGYSVTQTSKGEILRSTENLKVGTQITTKLSQGEIVS
EIIKIN

Sequences:

>Translated_486_residues
MNNILTITQLNYSVRNLLETELGQVWLTGEISNFSQPVSGHWYLTLKDENAQVRGAMFRMKNQRVTFRPQNGMQVLVRAS
VSLYEPRGDYQIIIESMQPAGDGLLQQQFEQLKMKLAAEGLFAQEKKKAIPPFAKRVGIITSSSGAALQDILNILKRRDP
SLAIIIYPTLVQGKEATQDIVNTIDLANRRRECDVLIVGRGGGSLEDLWCFNEEAVAHAIFRSDIPIISAVGHETDVTIA
DFVADLRAPTPSAAAELVSRDQQELVRQLQHQFDKLSLAFDRLWTEKQTYFERLKLRLNAQHPARQVQMQQQRLAQFSYR
LENAIHKTYLTEKQKLEQLLLRLTNQHPQRQLQQQQMQLKQAEYRLAQAIEQTLIRKQNQWKHIVEQVKRNPLPYCVEKK
NQQYAQLAQRLQFAIEKKLTKEQQAFQELCTRIDGLSPLKILARGYSVTQTSKGEILRSTENLKVGTQITTKLSQGEIVS
EIIKIN
>Mature_486_residues
MNNILTITQLNYSVRNLLETELGQVWLTGEISNFSQPVSGHWYLTLKDENAQVRGAMFRMKNQRVTFRPQNGMQVLVRAS
VSLYEPRGDYQIIIESMQPAGDGLLQQQFEQLKMKLAAEGLFAQEKKKAIPPFAKRVGIITSSSGAALQDILNILKRRDP
SLAIIIYPTLVQGKEATQDIVNTIDLANRRRECDVLIVGRGGGSLEDLWCFNEEAVAHAIFRSDIPIISAVGHETDVTIA
DFVADLRAPTPSAAAELVSRDQQELVRQLQHQFDKLSLAFDRLWTEKQTYFERLKLRLNAQHPARQVQMQQQRLAQFSYR
LENAIHKTYLTEKQKLEQLLLRLTNQHPQRQLQQQQMQLKQAEYRLAQAIEQTLIRKQNQWKHIVEQVKRNPLPYCVEKK
NQQYAQLAQRLQFAIEKKLTKEQQAFQELCTRIDGLSPLKILARGYSVTQTSKGEILRSTENLKVGTQITTKLSQGEIVS
EIIKIN

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=482, Percent_Identity=51.6597510373444, Blast_Score=479, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 55724; Mature: 55724

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNILTITQLNYSVRNLLETELGQVWLTGEISNFSQPVSGHWYLTLKDENAQVRGAMFRM
CCCEEEEEECCHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHHH
KNQRVTFRPQNGMQVLVRASVSLYEPRGDYQIIIESMQPAGDGLLQQQFEQLKMKLAAEG
CCCEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
LFAQEKKKAIPPFAKRVGIITSSSGAALQDILNILKRRDPSLAIIIYPTLVQGKEATQDI
HHHHHHHHCCCCHHHHHCCEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHH
VNTIDLANRRRECDVLIVGRGGGSLEDLWCFNEEAVAHAIFRSDIPIISAVGHETDVTIA
HHHHHHHCCCCCCCEEEEECCCCCCHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCCHHH
DFVADLRAPTPSAAAELVSRDQQELVRQLQHQFDKLSLAFDRLWTEKQTYFERLKLRLNA
HHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QHPARQVQMQQQRLAQFSYRLENAIHKTYLTEKQKLEQLLLRLTNQHPQRQLQQQQMQLK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
QAEYRLAQAIEQTLIRKQNQWKHIVEQVKRNPLPYCVEKKNQQYAQLAQRLQFAIEKKLT
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHH
KEQQAFQELCTRIDGLSPLKILARGYSVTQTSKGEILRSTENLKVGTQITTKLSQGEIVS
HHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCHHHCCCCCEECCHHHHHCCCCHHHH
EIIKIN
HHHHCC
>Mature Secondary Structure
MNNILTITQLNYSVRNLLETELGQVWLTGEISNFSQPVSGHWYLTLKDENAQVRGAMFRM
CCCEEEEEECCHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHHH
KNQRVTFRPQNGMQVLVRASVSLYEPRGDYQIIIESMQPAGDGLLQQQFEQLKMKLAAEG
CCCEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
LFAQEKKKAIPPFAKRVGIITSSSGAALQDILNILKRRDPSLAIIIYPTLVQGKEATQDI
HHHHHHHHCCCCHHHHHCCEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHH
VNTIDLANRRRECDVLIVGRGGGSLEDLWCFNEEAVAHAIFRSDIPIISAVGHETDVTIA
HHHHHHHCCCCCCCEEEEECCCCCCHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCCHHH
DFVADLRAPTPSAAAELVSRDQQELVRQLQHQFDKLSLAFDRLWTEKQTYFERLKLRLNA
HHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QHPARQVQMQQQRLAQFSYRLENAIHKTYLTEKQKLEQLLLRLTNQHPQRQLQQQQMQLK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
QAEYRLAQAIEQTLIRKQNQWKHIVEQVKRNPLPYCVEKKNQQYAQLAQRLQFAIEKKLT
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHH
KEQQAFQELCTRIDGLSPLKILARGYSVTQTSKGEILRSTENLKVGTQITTKLSQGEIVS
HHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCHHHCCCCCEECCHHHHHCCCCHHHH
EIIKIN
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA