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The map label for this gene is can [H]

Identifier: 126208206

GI number: 126208206

Start: 834060

End: 834776

Strand: Direct

Name: can [H]

Synonym: APL_0726

Alternate gene names: 126208206

Gene position: 834060-834776 (Clockwise)

Preceding gene: 126208205

Following gene: 126208207

Centisome position: 36.67

GC content: 42.26

Gene sequence:

>717_bases
ATGAAACAGATAGAAAAATTGTTTGCCAATAACCATGCTTGGGCAACTCGGATGAAAGACGAACAGTCGGATTATTTTAA
ACAACTTGCCGAGCATCAAAAGCCGACTTATCTTTGGATTGGCTGTTCGGACAGTCGTGTTCCGGCCGAAAAATTAACCG
GTTTAGGTCCGGGCGAGCTTTTTGTTCATCGTAACGTGGCAAATTTAGTTATCCATACCGATCTGAATTGTCTTTCCGTC
GTGCAATATGCGGTAGATGTATTGGAGATCGAACATATTATTATTTGCGGTCATACCAACTGCGGTGGTATCCAAGCTGC
AATTGGTACTGTCGAAGATTACGGTTTAATCAGCAACTGGTTATTGCATATTCGTGATCTGTGGTTTAAACACAGCTATT
TACTCGGTAATCTTCCCTCCGAGCAACGTGCCAATATGCTTACCCGCTTAAACGTTGCCGAGCAAGTTTATAACTTAGGG
CGCAGTTCTATTGTTACCGCCGCTTGGAAGCGAGGTAAGAAACTCTCGATTCACGGCTGGGTATATGATGTTAATGACGG
TTTCTTAATTGATCAGGGGGTAATCGCAACCAGTACGGAAACACTCGAAATTACTTATCGAAATGCGATTGCGAAACTTG
CGACGGAAGTGGAAGAAATGATCGCCAATAAACCCGTCGAACAATCAAATCCAATTGAAAATAATCATATTGATTAA

Upstream 100 bases:

>100_bases
AAGCGGTCGAATTTGTATAATTTTTACAAATTCGACCGCTTTTTTATTCTATGCTAGAATGCAGAAAGATTTAGTAACAA
ATTTTTAACAAGGCTGAACC

Downstream 100 bases:

>100_bases
CCGTATTTAAAAATAGTGTGATAAATCTCACACTATTTCCTTTTCTCACTACCTATTCCGAATATTTTTACCTTTCTTAA
CAAAAAAATTAAATTCTTCT

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MKQIEKLFANNHAWATRMKDEQSDYFKQLAEHQKPTYLWIGCSDSRVPAEKLTGLGPGELFVHRNVANLVIHTDLNCLSV
VQYAVDVLEIEHIIICGHTNCGGIQAAIGTVEDYGLISNWLLHIRDLWFKHSYLLGNLPSEQRANMLTRLNVAEQVYNLG
RSSIVTAAWKRGKKLSIHGWVYDVNDGFLIDQGVIATSTETLEITYRNAIAKLATEVEEMIANKPVEQSNPIENNHID

Sequences:

>Translated_238_residues
MKQIEKLFANNHAWATRMKDEQSDYFKQLAEHQKPTYLWIGCSDSRVPAEKLTGLGPGELFVHRNVANLVIHTDLNCLSV
VQYAVDVLEIEHIIICGHTNCGGIQAAIGTVEDYGLISNWLLHIRDLWFKHSYLLGNLPSEQRANMLTRLNVAEQVYNLG
RSSIVTAAWKRGKKLSIHGWVYDVNDGFLIDQGVIATSTETLEITYRNAIAKLATEVEEMIANKPVEQSNPIENNHID
>Mature_238_residues
MKQIEKLFANNHAWATRMKDEQSDYFKQLAEHQKPTYLWIGCSDSRVPAEKLTGLGPGELFVHRNVANLVIHTDLNCLSV
VQYAVDVLEIEHIIICGHTNCGGIQAAIGTVEDYGLISNWLLHIRDLWFKHSYLLGNLPSEQRANMLTRLNVAEQVYNLG
RSSIVTAAWKRGKKLSIHGWVYDVNDGFLIDQGVIATSTETLEITYRNAIAKLATEVEEMIANKPVEQSNPIENNHID

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=213, Percent_Identity=65.7276995305164, Blast_Score=297, Evalue=3e-82,
Organism=Escherichia coli, GI1786534, Length=168, Percent_Identity=37.5, Blast_Score=102, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324292, Length=194, Percent_Identity=31.4432989690722, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 26853; Mature: 26853

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIEKLFANNHAWATRMKDEQSDYFKQLAEHQKPTYLWIGCSDSRVPAEKLTGLGPGEL
CCHHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCCCCCE
FVHRNVANLVIHTDLNCLSVVQYAVDVLEIEHIIICGHTNCGGIQAAIGTVEDYGLISNW
EEECCCEEEEEECCCHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHCHHHHHHHHHH
LLHIRDLWFKHSYLLGNLPSEQRANMLTRLNVAEQVYNLGRSSIVTAAWKRGKKLSIHGW
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEE
VYDVNDGFLIDQGVIATSTETLEITYRNAIAKLATEVEEMIANKPVEQSNPIENNHID
EEECCCCEEEECCEEEECCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKQIEKLFANNHAWATRMKDEQSDYFKQLAEHQKPTYLWIGCSDSRVPAEKLTGLGPGEL
CCHHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCCCCCE
FVHRNVANLVIHTDLNCLSVVQYAVDVLEIEHIIICGHTNCGGIQAAIGTVEDYGLISNW
EEECCCEEEEEECCCHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHCHHHHHHHHHH
LLHIRDLWFKHSYLLGNLPSEQRANMLTRLNVAEQVYNLGRSSIVTAAWKRGKKLSIHGW
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEE
VYDVNDGFLIDQGVIATSTETLEITYRNAIAKLATEVEEMIANKPVEQSNPIENNHID
EEECCCCEEEECCEEEECCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]