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The map label for this gene is argA

Identifier: 126208178

GI number: 126208178

Start: 799732

End: 801045

Strand: Reverse

Name: argA

Synonym: APL_0698

Alternate gene names: 126208178

Gene position: 801045-799732 (Counterclockwise)

Preceding gene: 126208179

Following gene: 126208176

Centisome position: 35.22

GC content: 41.86

Gene sequence:

>1314_bases
ATGCGTAACACAGAATTAGTCCAATGGTTTAGACAATCCACGCCTTACGTAAATATGCACAGAGAGAAAACCTTTGTGAT
TATGTTAGACGGCAATGCGATTGCTCACCCGAATTTTATTAATATTACCAACGATATTGGATTGCTCCATAGTTTAGGTA
TCAAACTGGTTATCGTGTTTGGTGCTCGTTGCCAAATTGACGAGTTATTGGCAAAAAATCAGATGAGTTCCACCTATCAT
AAGCATATTCGTATTACCGATAGCAAAACGTTAGAAGTGGTTAAGCAAGCGGTCGGCGGATTGCATTATGATATTTTTTC
TCGTTTGTCATTACGTTTGCCGAATTCTCCGGTACTAAACGTAGTAAGTAGCAATGCGGTATTAGCGCAACCGCTTGGTG
TAATTGACGGTGTGGATTACGGGTTAAGCGGTAAGATTCGCCGGATTAATATCGAAGGGATTCAGCAACAATTGGCACAA
GATGCGATTGTGGTTATCGGTCCGATTGCGCCTTCGGTTACCGGAGAAATGTTTAATTTACCGTTTGAGGAGATTGCAAC
GCAAATTGCGATTAAGCTAAAAGCGGATAAGCTAATCGGTTTTTGCGATCAGCAAGGGATCTTGGATTCGGAAGGCAATG
TGTTATCGGATTTACACCCTCGTGAAGCTAAACGTTATTTAACGCAGTTTATTGAGTCCGGACAATATCATCATTCCGCC
GCGCGCTTTTTACAAGCGGCAATCGAAGCTTGCCATGCCGGAATTAAACGTTCGCATTTACTGAGCTATAAGGAAGACGG
TTCATTACTGCAAGAGTTATTTTCTCGTGACGGTATCGGTACGCAGTTATCGGAAGAGAGTTCGGAAAATATTCGTTTGG
CAACCTCATTTGATATTCCCGGTTTGTTAAATTTGATTCGACCGTTAGAAGAACAAGGCATTTTAGTAAAACGCTCGCGT
GAACAATTAGAAATGGAAATCAGCAATTATACCATTATTGAGCGTGACGGCATTGTGATTGCCTGTGCGGCATTGAATCA
TTATCCGCAAGAAAAAATGGCGGAAATGGCGTGTGTGGCGGTTCATCCCGATTATCGAGATTCATCACGAGGCGATGTAT
TATTAGAAGCGATTAAACGCCGCGCCTATAAATTACAAGTTGAGAAATTATTTGTGCTAACGACACGCACAACCCAGTGG
TTTCAAGAGCGCGGCTTTGTACTTTCCACAACGGACGATTTACCGAAAGAGAAACGTGAACATTATAACTATCAACGAAT
GTCAAAGATTTTAATCCTAGATCTCGGACAGTAA

Upstream 100 bases:

>100_bases
CCGCTTTTTTATGGACAGATACAAATTTTAATTCAATAAAATTGCATAAATATTCATTTTAATATACATTTGTCAGAAAC
AAAAAAATAATGAGGAAGTT

Downstream 100 bases:

>100_bases
GCGGTTGGATTTTATTGAATATTCGCAAACGCCTTTCCTTAAAAGAAAGGCGTTTTGTTTTTTCAAAAAATAGAAAATCA
AACCGTTTATTACTTATTTC

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MRNTELVQWFRQSTPYVNMHREKTFVIMLDGNAIAHPNFINITNDIGLLHSLGIKLVIVFGARCQIDELLAKNQMSSTYH
KHIRITDSKTLEVVKQAVGGLHYDIFSRLSLRLPNSPVLNVVSSNAVLAQPLGVIDGVDYGLSGKIRRINIEGIQQQLAQ
DAIVVIGPIAPSVTGEMFNLPFEEIATQIAIKLKADKLIGFCDQQGILDSEGNVLSDLHPREAKRYLTQFIESGQYHHSA
ARFLQAAIEACHAGIKRSHLLSYKEDGSLLQELFSRDGIGTQLSEESSENIRLATSFDIPGLLNLIRPLEEQGILVKRSR
EQLEMEISNYTIIERDGIVIACAALNHYPQEKMAEMACVAVHPDYRDSSRGDVLLEAIKRRAYKLQVEKLFVLTTRTTQW
FQERGFVLSTTDDLPKEKREHYNYQRMSKILILDLGQ

Sequences:

>Translated_437_residues
MRNTELVQWFRQSTPYVNMHREKTFVIMLDGNAIAHPNFINITNDIGLLHSLGIKLVIVFGARCQIDELLAKNQMSSTYH
KHIRITDSKTLEVVKQAVGGLHYDIFSRLSLRLPNSPVLNVVSSNAVLAQPLGVIDGVDYGLSGKIRRINIEGIQQQLAQ
DAIVVIGPIAPSVTGEMFNLPFEEIATQIAIKLKADKLIGFCDQQGILDSEGNVLSDLHPREAKRYLTQFIESGQYHHSA
ARFLQAAIEACHAGIKRSHLLSYKEDGSLLQELFSRDGIGTQLSEESSENIRLATSFDIPGLLNLIRPLEEQGILVKRSR
EQLEMEISNYTIIERDGIVIACAALNHYPQEKMAEMACVAVHPDYRDSSRGDVLLEAIKRRAYKLQVEKLFVLTTRTTQW
FQERGFVLSTTDDLPKEKREHYNYQRMSKILILDLGQ
>Mature_437_residues
MRNTELVQWFRQSTPYVNMHREKTFVIMLDGNAIAHPNFINITNDIGLLHSLGIKLVIVFGARCQIDELLAKNQMSSTYH
KHIRITDSKTLEVVKQAVGGLHYDIFSRLSLRLPNSPVLNVVSSNAVLAQPLGVIDGVDYGLSGKIRRINIEGIQQQLAQ
DAIVVIGPIAPSVTGEMFNLPFEEIATQIAIKLKADKLIGFCDQQGILDSEGNVLSDLHPREAKRYLTQFIESGQYHHSA
ARFLQAAIEACHAGIKRSHLLSYKEDGSLLQELFSRDGIGTQLSEESSENIRLATSFDIPGLLNLIRPLEEQGILVKRSR
EQLEMEISNYTIIERDGIVIACAALNHYPQEKMAEMACVAVHPDYRDSSRGDVLLEAIKRRAYKLQVEKLFVLTTRTTQW
FQERGFVLSTTDDLPKEKREHYNYQRMSKILILDLGQ

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain

Homologues:

Organism=Escherichia coli, GI1789181, Length=439, Percent_Identity=61.0478359908884, Blast_Score=545, Evalue=1e-156,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGA_ACTP2 (A3N062)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053403.1
- ProteinModelPortal:   A3N062
- SMR:   A3N062
- STRING:   A3N062
- GeneID:   4848575
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0698
- eggNOG:   COG0548
- HOGENOM:   HBG545264
- OMA:   APYIHAF
- PhylomeDB:   A3N062
- ProtClustDB:   PRK05279
- BioCyc:   APLE416269:APL_0698-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01105
- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167
- Gene3D:   G3DSA:3.40.1160.10
- Gene3D:   G3DSA:3.40.630.30
- PIRSF:   PIRSF000423
- TIGRFAMs:   TIGR01890

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1; SSF53633 Aa_kinase; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.1.1

Molecular weight: Translated: 49292; Mature: 49292

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS51186 GNAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNTELVQWFRQSTPYVNMHREKTFVIMLDGNAIAHPNFINITNDIGLLHSLGIKLVIVF
CCCHHHHHHHHHCCCEEEEECCEEEEEEECCCEECCCCEEEECCCHHHHHHCCEEEEEEE
GARCQIDELLAKNQMSSTYHKHIRITDSKTLEVVKQAVGGLHYDIFSRLSLRLPNSPVLN
CCCCCHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHH
VVSSNAVLAQPLGVIDGVDYGLSGKIRRINIEGIQQQLAQDAIVVIGPIAPSVTGEMFNL
EECCCCEEECCCCHHCCCCCCCCCCEEEEEHHHHHHHHHCCCEEEEECCCCCCCCHHHCC
PFEEIATQIAIKLKADKLIGFCDQQGILDSEGNVLSDLHPREAKRYLTQFIESGQYHHSA
CHHHHHHHHEEEEEHHHHHEECCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCCHHHH
ARFLQAAIEACHAGIKRSHLLSYKEDGSLLQELFSRDGIGTQLSEESSENIRLATSFDIP
HHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCH
GLLNLIRPLEEQGILVKRSREQLEMEISNYTIIERDGIVIACAALNHYPQEKMAEMACVA
HHHHHHHHHHHCCEEEECCHHHHHEECCCEEEEECCCEEEEEHHHCCCCHHHHHHEEEEE
VHPDYRDSSRGDVLLEAIKRRAYKLQVEKLFVLTTRTTQWFQERGFVLSTTDDLPKEKRE
ECCCCCCCCCHHHHHHHHHHHHHEEEEEEEEEEEECHHHHHHHCCCEEECCCCCCHHHHH
HYNYQRMSKILILDLGQ
HCCHHHHCEEEEEECCC
>Mature Secondary Structure
MRNTELVQWFRQSTPYVNMHREKTFVIMLDGNAIAHPNFINITNDIGLLHSLGIKLVIVF
CCCHHHHHHHHHCCCEEEEECCEEEEEEECCCEECCCCEEEECCCHHHHHHCCEEEEEEE
GARCQIDELLAKNQMSSTYHKHIRITDSKTLEVVKQAVGGLHYDIFSRLSLRLPNSPVLN
CCCCCHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHH
VVSSNAVLAQPLGVIDGVDYGLSGKIRRINIEGIQQQLAQDAIVVIGPIAPSVTGEMFNL
EECCCCEEECCCCHHCCCCCCCCCCEEEEEHHHHHHHHHCCCEEEEECCCCCCCCHHHCC
PFEEIATQIAIKLKADKLIGFCDQQGILDSEGNVLSDLHPREAKRYLTQFIESGQYHHSA
CHHHHHHHHEEEEEHHHHHEECCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCCHHHH
ARFLQAAIEACHAGIKRSHLLSYKEDGSLLQELFSRDGIGTQLSEESSENIRLATSFDIP
HHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCH
GLLNLIRPLEEQGILVKRSREQLEMEISNYTIIERDGIVIACAALNHYPQEKMAEMACVA
HHHHHHHHHHHCCEEEECCHHHHHEECCCEEEEECCCEEEEEHHHCCCCHHHHHHEEEEE
VHPDYRDSSRGDVLLEAIKRRAYKLQVEKLFVLTTRTTQWFQERGFVLSTTDDLPKEKRE
ECCCCCCCCCHHHHHHHHHHHHHEEEEEEEEEEEECHHHHHHHCCCEEECCCCCCHHHHH
HYNYQRMSKILILDLGQ
HCCHHHHCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA