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The map label for this gene is moaE [H]

Identifier: 126208173

GI number: 126208173

Start: 793098

End: 793553

Strand: Direct

Name: moaE [H]

Synonym: APL_0693

Alternate gene names: 126208173

Gene position: 793098-793553 (Clockwise)

Preceding gene: 126208172

Following gene: 126208174

Centisome position: 34.87

GC content: 44.52

Gene sequence:

>456_bases
ATGCACACTACGTTAATCGAAGTTCAACAAGAAACCTTTGATCAAAATGCGATTTATCGTTGGTTAAGCGAACATCATAG
CGTTGGAGCAACTACGCTTTTTGTCGGTAAAGTACGAGAAATGAATTTAGGCGATAATGTGTCCGGTTTATATCTGGAAC
ACTACCCTGCAATGACTAAAAAAGCCCTCCAAGAAATTGTGGATGAGGCTCGTAAGCGTTGGGGTTTGCAACGTGTTGCG
GTAATTCATCGTATTGGGCAACTGCATACCGGCGATGAAATTGTATTGGTTGGGGTAAGTTCCGCTCACCGAGGCGATGC
TTATCACGCCAACGAATTTATCATGGACTATCTGAAAACTCGTGCGCCGTTTTGGAAACGTGAAACCACACAAGACGGTG
ATCGCTGGATAGAAGGCAGAGAAAGCGACCAACTTGAAGCGGATAAATGGCAATGA

Upstream 100 bases:

>100_bases
CAAATTATTAGTGGCAATTAACCAAAGCATTTCGCCGTTGGAAAGTGCAATCAAAGACGGTGATGAAGTCGCGTTCTTCC
CACCGGTAACAGGAGGCTAA

Downstream 100 bases:

>100_bases
ATCACGCCCTTAGATTCACGGAATGTGTCAGAAAGTTTATAATATTCGACAACATTCTGTTTTTTATATATTGAGCATTT
ATGACAACACCAATTATTGA

Product: molybdopterin-converting factor subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MHTTLIEVQQETFDQNAIYRWLSEHHSVGATTLFVGKVREMNLGDNVSGLYLEHYPAMTKKALQEIVDEARKRWGLQRVA
VIHRIGQLHTGDEIVLVGVSSAHRGDAYHANEFIMDYLKTRAPFWKRETTQDGDRWIEGRESDQLEADKWQ

Sequences:

>Translated_151_residues
MHTTLIEVQQETFDQNAIYRWLSEHHSVGATTLFVGKVREMNLGDNVSGLYLEHYPAMTKKALQEIVDEARKRWGLQRVA
VIHRIGQLHTGDEIVLVGVSSAHRGDAYHANEFIMDYLKTRAPFWKRETTQDGDRWIEGRESDQLEADKWQ
>Mature_151_residues
MHTTLIEVQQETFDQNAIYRWLSEHHSVGATTLFVGKVREMNLGDNVSGLYLEHYPAMTKKALQEIVDEARKRWGLQRVA
VIHRIGQLHTGDEIVLVGVSSAHRGDAYHANEFIMDYLKTRAPFWKRETTQDGDRWIEGRESDQLEADKWQ

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=115, Percent_Identity=32.1739130434783, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1787003, Length=150, Percent_Identity=62.6666666666667, Blast_Score=193, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17509279, Length=130, Percent_Identity=32.3076923076923, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21356259, Length=119, Percent_Identity=36.1344537815126, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17521; Mature: 17521

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTTLIEVQQETFDQNAIYRWLSEHHSVGATTLFVGKVREMNLGDNVSGLYLEHYPAMTK
CCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEHHHEECCCCCCCCCHHHHHHHHHHH
KALQEIVDEARKRWGLQRVAVIHRIGQLHTGDEIVLVGVSSAHRGDAYHANEFIMDYLKT
HHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
RAPFWKRETTQDGDRWIEGRESDQLEADKWQ
CCCCCCCCCCCCHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHTTLIEVQQETFDQNAIYRWLSEHHSVGATTLFVGKVREMNLGDNVSGLYLEHYPAMTK
CCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEHHHEECCCCCCCCCHHHHHHHHHHH
KALQEIVDEARKRWGLQRVAVIHRIGQLHTGDEIVLVGVSSAHRGDAYHANEFIMDYLKT
HHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
RAPFWKRETTQDGDRWIEGRESDQLEADKWQ
CCCCCCCCCCCCHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA