Click here to switch to the map view.

The map label for this gene is torZ [H]

Identifier: 126208168

GI number: 126208168

Start: 786946

End: 789420

Strand: Reverse

Name: torZ [H]

Synonym: APL_0688

Alternate gene names: 126208168

Gene position: 789420-786946 (Counterclockwise)

Preceding gene: 126208169

Following gene: 126208166

Centisome position: 34.71

GC content: 43.15

Gene sequence:

>2475_bases
ATGAAAACTCAAGAAAAAATTAATGCAAGTCGTCGTGGTTTTATTAAAAATACCTCTCTCGGTCTTGCTGGGACATCTTT
AGCGGGCGGTAGTGTAAATGCCTTAATTTCAACGGAAGCGGCCGCAGCGGAGATGCAAACCGTAATGACAGCAGCACACT
GGGGGGCGTTAGGTATCGTGGTTGAAAACGGTAAAGTGGTTAGATCCGGTCCTGCTATGCCTCCGTCAATCGAAAACGAA
TTACAAACTGTCGTGCCTGATCAAGTACACGGTGAAACTCGCGTTAAATATCCGATGGTACGTAAAGGTTACTTAGAAGG
TAATAAAGATACGACTTTACGTGGTCGTGATGAGTGGGTACGTGTTTCTTGGGATAAAGCGTTTGAATTAGTTGCAAACG
AAATGAAACGTGTGCGTGACGCACATGGCCCAAGTGCAATTTTCGGCGGTTCTTACGGCTGGTATAGCTCAGGCTCATTA
CACGCAGCACGTACATTATTACAACGTTATCTAAACATTACCGGCGGTTTTGTCGGCGTGAAAGGCGACTATTCAACCGG
TGCGGCACAAGTGATTATGCCGCACGTATTGGGAACGATCGAAGTGTATGAACAACAAACCAGCTGGGAAGTTGTTTTAG
AAAGCACGGATGTGATCGTGTTATGGTCGGCAAACCCGTTAAATACGTTGCGTATTGCTTGGACTTCGACTGATCAACAA
GGTTTGGAATACTTCAAAAAATTCAAAGAAAGCGGTAAGCGTATTATCTGTATTGACCCAGTAAGAAGCGAAAGTTGCGA
ATATTTAGGTGCAGAGTGGGTTCCGGTTCATACGGGAACGGACGTAGCGTTAATGTTAGGTATGGCGCATACCTTAGTCG
CAGAAAATAAACACGATAAAGAATTCCTTAAAAAATATACTAAAGGCTATGAACAATTTGAAAAATACTTGCTTGGTACG
GAAGATAAACAGCCGAAAGATGCGGAATGGGCAAGCAAAATTTGTGGCGTACCGGCGGAAACCATCAAAAAATTGGCATT
AGAGTTACAAAGCAAACGTACGATGTTAATGGCAGGTTGGGGTATCCAACGCCAACGTCACGGTGAACAAAGTCACTGGA
TGTTAGTGACATTAGCGGCAATGTTAGGTCAAATCGGTTTACCGGGCGGTGGTTTCGGTTTAAGTTATCACTATTCAAAC
GGTGGTGTACCGACTGCAACCGGTGGTATTTTAGGATCAATTTCGGCAAATCCGACAACTGAAGCGGGTGCAAAAACTTG
GTTGGATGAAACCTCTAAATTCTCTTTCCCGCTTGCTCGCATTTCCGATGCGTTATTAAATCCGGGTAAAACCATTGACT
ATAACGGCACAAAAGTGACTTATCCGGATATTAAAGTAATTTGGTGGTCAGGCGGTAACCCGTTTACGCATCACCAAGAC
ACCAATACCTTAGTAAAAGCGTGGCAAAAACCGGACAGTGTGTTTGTCACCGAATGTCACTGGACACCAACCGCACGTAT
GGCGGATATTGTTTTACCGGCAACAACAAGTTATGAGCGTAATGACTTAACGATGTCAGGAGATTATTCAATGATGAATA
TTTTCCCAATGAAGCAAGTTGTTCCGCCGCAATTTGAAGCGAAAAACGACTACGATATTTTTGCAGAGCTTTCAAAACGT
GCAGGTAAAGAACAAGAATTTACCGAAGGTAAATCGGAAATGGATTGGTTAAAAGGTTTCTATCAAACTGCATTTGATGC
GGCACGTAAAAACCGTGTATTAATGCCTAAATTTGAACAGTTCTGGGCGGATAACAAGCCGATTACCTTTAAAGCGACTG
AAAAAGCGAAAAAATGGGTACGTTATGAAGAATTCCGTAACGATCCGTTACTCAATCCATTAGGTACACCATCAGGCAAA
ATTGAAATTTTCTCTGATGTAGTGGCGAAAATGAATTACGATGATTGTAAAGGTCATCCGACTTGGATGGAACACGAAGA
GTTCGCCGGTAACGCAACCGAAGAAGCACCGCTTGCATTAGTCACTCCACACTCAAAATATCGTTTACATAGTCAATTAG
CTTACAGCGCATTGCGTAAACTTTATGCGGTAAATGATCGTGAGCCGGTATTAATTAATACCGAAGATGCAGCTGCGCGT
GGTATTGCAAACGGTGACATCGTGCGTATTTTCAATAAACGTGGTCAAGTGTTAGCAGGTGCAGTGGTAACAGACGGTAT
CATTAAAGGCACTGTAGCGTTACACGAAGGGGCTTGGTACGATCCGATGGATCTCGGTAAATCGGAACAACCGCTTTGTA
AAAACGGTAATCCAAATGTGTTAACACGTGATGAAGGTACATCAAAATTAGCACAAGGTAACTCACCGAATACGGCAACG
GTACAAGTAGAGAAATTTACCGGCGTTGCACCGGAAGTAACAGTATTTAAAGAACCGAAATATACACAAGCATAG

Upstream 100 bases:

>100_bases
CAAAATCAGACCGCTTACACACCGGATAGTAAAGAAATGCACTATCCCCTCGTGTTTAGAAAGGTGTCAAATTCAACTTA
ACTTTCAGAGGGTTATGCAT

Downstream 100 bases:

>100_bases
TGTTATAGAATAAGTAAACAAAACGCACTAAAGTGAAGGGCTTTAGTGCGTTTTTATATTTATATTAACTGAATGACAAG
CGGTTATTTTTTTAATTTTC

Product: trimethylamine-N-oxide reductase precursor

Products: NA

Alternate protein names: TMAO reductase; Trimethylamine oxidase [H]

Number of amino acids: Translated: 824; Mature: 824

Protein sequence:

>824_residues
MKTQEKINASRRGFIKNTSLGLAGTSLAGGSVNALISTEAAAAEMQTVMTAAHWGALGIVVENGKVVRSGPAMPPSIENE
LQTVVPDQVHGETRVKYPMVRKGYLEGNKDTTLRGRDEWVRVSWDKAFELVANEMKRVRDAHGPSAIFGGSYGWYSSGSL
HAARTLLQRYLNITGGFVGVKGDYSTGAAQVIMPHVLGTIEVYEQQTSWEVVLESTDVIVLWSANPLNTLRIAWTSTDQQ
GLEYFKKFKESGKRIICIDPVRSESCEYLGAEWVPVHTGTDVALMLGMAHTLVAENKHDKEFLKKYTKGYEQFEKYLLGT
EDKQPKDAEWASKICGVPAETIKKLALELQSKRTMLMAGWGIQRQRHGEQSHWMLVTLAAMLGQIGLPGGGFGLSYHYSN
GGVPTATGGILGSISANPTTEAGAKTWLDETSKFSFPLARISDALLNPGKTIDYNGTKVTYPDIKVIWWSGGNPFTHHQD
TNTLVKAWQKPDSVFVTECHWTPTARMADIVLPATTSYERNDLTMSGDYSMMNIFPMKQVVPPQFEAKNDYDIFAELSKR
AGKEQEFTEGKSEMDWLKGFYQTAFDAARKNRVLMPKFEQFWADNKPITFKATEKAKKWVRYEEFRNDPLLNPLGTPSGK
IEIFSDVVAKMNYDDCKGHPTWMEHEEFAGNATEEAPLALVTPHSKYRLHSQLAYSALRKLYAVNDREPVLINTEDAAAR
GIANGDIVRIFNKRGQVLAGAVVTDGIIKGTVALHEGAWYDPMDLGKSEQPLCKNGNPNVLTRDEGTSKLAQGNSPNTAT
VQVEKFTGVAPEVTVFKEPKYTQA

Sequences:

>Translated_824_residues
MKTQEKINASRRGFIKNTSLGLAGTSLAGGSVNALISTEAAAAEMQTVMTAAHWGALGIVVENGKVVRSGPAMPPSIENE
LQTVVPDQVHGETRVKYPMVRKGYLEGNKDTTLRGRDEWVRVSWDKAFELVANEMKRVRDAHGPSAIFGGSYGWYSSGSL
HAARTLLQRYLNITGGFVGVKGDYSTGAAQVIMPHVLGTIEVYEQQTSWEVVLESTDVIVLWSANPLNTLRIAWTSTDQQ
GLEYFKKFKESGKRIICIDPVRSESCEYLGAEWVPVHTGTDVALMLGMAHTLVAENKHDKEFLKKYTKGYEQFEKYLLGT
EDKQPKDAEWASKICGVPAETIKKLALELQSKRTMLMAGWGIQRQRHGEQSHWMLVTLAAMLGQIGLPGGGFGLSYHYSN
GGVPTATGGILGSISANPTTEAGAKTWLDETSKFSFPLARISDALLNPGKTIDYNGTKVTYPDIKVIWWSGGNPFTHHQD
TNTLVKAWQKPDSVFVTECHWTPTARMADIVLPATTSYERNDLTMSGDYSMMNIFPMKQVVPPQFEAKNDYDIFAELSKR
AGKEQEFTEGKSEMDWLKGFYQTAFDAARKNRVLMPKFEQFWADNKPITFKATEKAKKWVRYEEFRNDPLLNPLGTPSGK
IEIFSDVVAKMNYDDCKGHPTWMEHEEFAGNATEEAPLALVTPHSKYRLHSQLAYSALRKLYAVNDREPVLINTEDAAAR
GIANGDIVRIFNKRGQVLAGAVVTDGIIKGTVALHEGAWYDPMDLGKSEQPLCKNGNPNVLTRDEGTSKLAQGNSPNTAT
VQVEKFTGVAPEVTVFKEPKYTQA
>Mature_824_residues
MKTQEKINASRRGFIKNTSLGLAGTSLAGGSVNALISTEAAAAEMQTVMTAAHWGALGIVVENGKVVRSGPAMPPSIENE
LQTVVPDQVHGETRVKYPMVRKGYLEGNKDTTLRGRDEWVRVSWDKAFELVANEMKRVRDAHGPSAIFGGSYGWYSSGSL
HAARTLLQRYLNITGGFVGVKGDYSTGAAQVIMPHVLGTIEVYEQQTSWEVVLESTDVIVLWSANPLNTLRIAWTSTDQQ
GLEYFKKFKESGKRIICIDPVRSESCEYLGAEWVPVHTGTDVALMLGMAHTLVAENKHDKEFLKKYTKGYEQFEKYLLGT
EDKQPKDAEWASKICGVPAETIKKLALELQSKRTMLMAGWGIQRQRHGEQSHWMLVTLAAMLGQIGLPGGGFGLSYHYSN
GGVPTATGGILGSISANPTTEAGAKTWLDETSKFSFPLARISDALLNPGKTIDYNGTKVTYPDIKVIWWSGGNPFTHHQD
TNTLVKAWQKPDSVFVTECHWTPTARMADIVLPATTSYERNDLTMSGDYSMMNIFPMKQVVPPQFEAKNDYDIFAELSKR
AGKEQEFTEGKSEMDWLKGFYQTAFDAARKNRVLMPKFEQFWADNKPITFKATEKAKKWVRYEEFRNDPLLNPLGTPSGK
IEIFSDVVAKMNYDDCKGHPTWMEHEEFAGNATEEAPLALVTPHSKYRLHSQLAYSALRKLYAVNDREPVLINTEDAAAR
GIANGDIVRIFNKRGQVLAGAVVTDGIIKGTVALHEGAWYDPMDLGKSEQPLCKNGNPNVLTRDEGTSKLAQGNSPNTAT
VQVEKFTGVAPEVTVFKEPKYTQA

Specific function: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081994, Length=821, Percent_Identity=56.0292326431181, Blast_Score=933, Evalue=0.0,
Organism=Escherichia coli, GI145693196, Length=785, Percent_Identity=53.3757961783439, Blast_Score=863, Evalue=0.0,
Organism=Escherichia coli, GI1787231, Length=840, Percent_Identity=45.5952380952381, Blast_Score=719, Evalue=0.0,
Organism=Escherichia coli, GI87081797, Length=754, Percent_Identity=32.8912466843501, Blast_Score=322, Evalue=6e-89,
Organism=Escherichia coli, GI1787870, Length=874, Percent_Identity=30.3203661327231, Blast_Score=292, Evalue=7e-80,
Organism=Escherichia coli, GI171474008, Length=744, Percent_Identity=30.3763440860215, Blast_Score=258, Evalue=2e-69,
Organism=Escherichia coli, GI3868721, Length=764, Percent_Identity=22.6439790575916, Blast_Score=137, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.7.2.3 [H]

Molecular weight: Translated: 91252; Mature: 91252

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2 ; PS00932 MOLYBDOPTERIN_PROK_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTQEKINASRRGFIKNTSLGLAGTSLAGGSVNALISTEAAAAEMQTVMTAAHWGALGIV
CCCHHHHCHHHCCCEECCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCEEEEE
VENGKVVRSGPAMPPSIENELQTVVPDQVHGETRVKYPMVRKGYLEGNKDTTLRGRDEWV
EECCEEEECCCCCCCCHHHHHHHHCCCCCCCCCEECCCHHHCCCCCCCCCCEECCCCCEE
RVSWDKAFELVANEMKRVRDAHGPSAIFGGSYGWYSSGSLHAARTLLQRYLNITGGFVGV
EEEHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEE
KGDYSTGAAQVIMPHVLGTIEVYEQQTSWEVVLESTDVIVLWSANPLNTLRIAWTSTDQQ
CCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCEEEEEEECCCHH
GLEYFKKFKESGKRIICIDPVRSESCEYLGAEWVPVHTGTDVALMLGMAHTLVAENKHDK
HHHHHHHHHHCCCEEEEECCCCCCCHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHH
EFLKKYTKGYEQFEKYLLGTEDKQPKDAEWASKICGVPAETIKKLALELQSKRTMLMAGW
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECC
GIQRQRHGEQSHWMLVTLAAMLGQIGLPGGGFGLSYHYSNGGVPTATGGILGSISANPTT
CCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCCC
EAGAKTWLDETSKFSFPLARISDALLNPGKTIDYNGTKVTYPDIKVIWWSGGNPFTHHQD
CHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEECCCCEEECCCEEEEEECCCCCCCCCCC
TNTLVKAWQKPDSVFVTECHWTPTARMADIVLPATTSYERNDLTMSGDYSMMNIFPMKQV
CHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCEECCCCCEEEEECHHHC
VPPQFEAKNDYDIFAELSKRAGKEQEFTEGKSEMDWLKGFYQTAFDAARKNRVLMPKFEQ
CCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
FWADNKPITFKATEKAKKWVRYEEFRNDPLLNPLGTPSGKIEIFSDVVAKMNYDDCKGHP
HCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCC
TWMEHEEFAGNATEEAPLALVTPHSKYRLHSQLAYSALRKLYAVNDREPVLINTEDAAAR
CCCCCHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHC
GIANGDIVRIFNKRGQVLAGAVVTDGIIKGTVALHEGAWYDPMDLGKSEQPLCKNGNPNV
CCCCCCEEEEECCCCCEEEEHHHHCCHHCCEEEEECCCCCCHHHCCCCCCCCCCCCCCCE
LTRDEGTSKLAQGNSPNTATVQVEKFTGVAPEVTVFKEPKYTQA
EECCCCCHHHHCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MKTQEKINASRRGFIKNTSLGLAGTSLAGGSVNALISTEAAAAEMQTVMTAAHWGALGIV
CCCHHHHCHHHCCCEECCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCEEEEE
VENGKVVRSGPAMPPSIENELQTVVPDQVHGETRVKYPMVRKGYLEGNKDTTLRGRDEWV
EECCEEEECCCCCCCCHHHHHHHHCCCCCCCCCEECCCHHHCCCCCCCCCCEECCCCCEE
RVSWDKAFELVANEMKRVRDAHGPSAIFGGSYGWYSSGSLHAARTLLQRYLNITGGFVGV
EEEHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEE
KGDYSTGAAQVIMPHVLGTIEVYEQQTSWEVVLESTDVIVLWSANPLNTLRIAWTSTDQQ
CCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCEEEEEEECCCHH
GLEYFKKFKESGKRIICIDPVRSESCEYLGAEWVPVHTGTDVALMLGMAHTLVAENKHDK
HHHHHHHHHHCCCEEEEECCCCCCCHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHH
EFLKKYTKGYEQFEKYLLGTEDKQPKDAEWASKICGVPAETIKKLALELQSKRTMLMAGW
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECC
GIQRQRHGEQSHWMLVTLAAMLGQIGLPGGGFGLSYHYSNGGVPTATGGILGSISANPTT
CCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCCC
EAGAKTWLDETSKFSFPLARISDALLNPGKTIDYNGTKVTYPDIKVIWWSGGNPFTHHQD
CHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEECCCCEEECCCEEEEEECCCCCCCCCCC
TNTLVKAWQKPDSVFVTECHWTPTARMADIVLPATTSYERNDLTMSGDYSMMNIFPMKQV
CHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCEECCCCCEEEEECHHHC
VPPQFEAKNDYDIFAELSKRAGKEQEFTEGKSEMDWLKGFYQTAFDAARKNRVLMPKFEQ
CCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
FWADNKPITFKATEKAKKWVRYEEFRNDPLLNPLGTPSGKIEIFSDVVAKMNYDDCKGHP
HCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCC
TWMEHEEFAGNATEEAPLALVTPHSKYRLHSQLAYSALRKLYAVNDREPVLINTEDAAAR
CCCCCHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHC
GIANGDIVRIFNKRGQVLAGAVVTDGIIKGTVALHEGAWYDPMDLGKSEQPLCKNGNPNV
CCCCCCEEEEECCCCCEEEEHHHHCCHHCCEEEEECCCCCCHHHCCCCCCCCCCCCCCCE
LTRDEGTSKLAQGNSPNTATVQVEKFTGVAPEVTVFKEPKYTQA
EECCCCCHHHHCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]