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The map label for this gene is dapB

Identifier: 126208164

GI number: 126208164

Start: 782228

End: 783037

Strand: Reverse

Name: dapB

Synonym: APL_0684

Alternate gene names: 126208164

Gene position: 783037-782228 (Counterclockwise)

Preceding gene: 126208165

Following gene: 126208163

Centisome position: 34.43

GC content: 46.05

Gene sequence:

>810_bases
ATGACATTAAAAATCGGGATCGTCGGTGCCGGCGGTCGTATGGGACGCAACCTGATTACTGCGGTACAAAATGCGGAAGG
CGTGGAGTTAGGAGCAGCATTTGAACGTAAAGGTTCAAGTTTAGTCGGTGCGGACGCCGGTGAAGTGGCGGGCATTGGTG
CAACAGGGGTAAAAATCAGTGATGATTTAAACCAAAATACCAATTTTGACGTATTAATTGATTTTACCCGTCCGGAAGGC
ACGCTCGAGCATATTAAATTTTGTGTAGCAAACGGTAAAAAAATGGTCATCGGTACAACCGGTTTTGATGATGCGGGTAA
ACAAGCGATTCAAACGGCGGCAGAGCAAATTTCGATTGTGTTTGCTTCTAATTATAGTGTCGGTGTGAACCTCGTATTCA
AATTATTAGAAAAAGCGGCAAAAGTGATGGGCGATTATTGCGATATCGAAGTGATTGAAGCTCACCACCGTCATAAAGTG
GACGCACCGTCCGGCACAGCACTATCAATGGGCGAACATATCGCTAAAACACTTGGACGTGATCTCAAAACGCACGGTGT
ATTTGCCCGAGAAGGCATTACCGGCGAACGTAAACGTGATGAAATCGGTTTTGCAACCATTCGTGCTGGCGATGTGGTCG
GCGAACACTCGGTATGGTTTGCCGATGAAGGCGAAAGAGTGGAAATTGCTCATAAAGCGTCTAGCCGTATGACGTTCGCC
AACGGTGCGGTACGTGCGGCAAAATGGTTGAATACAAAACAAAACGGTCTGTTTGATATGACGGATGTGCTGGATTTGAA
TAACTTATAA

Upstream 100 bases:

>100_bases
AACATAAATAAGCGGTAAAATTTTTACAATATTTTGCAAATTTATGGCAAAATCAGACCGCTTATTTTAACAAGAACAAG
ACGTTATAGAGGAAGACACA

Downstream 100 bases:

>100_bases
CTAATTGAAATATTAGAAAGGATACACCTAGCGTGTCCCTATTGGTAAAATTGCAAGAATTGTGTATAGGGGCGCATTGA
GTGTGTCCAAAATAAACTCA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MTLKIGIVGAGGRMGRNLITAVQNAEGVELGAAFERKGSSLVGADAGEVAGIGATGVKISDDLNQNTNFDVLIDFTRPEG
TLEHIKFCVANGKKMVIGTTGFDDAGKQAIQTAAEQISIVFASNYSVGVNLVFKLLEKAAKVMGDYCDIEVIEAHHRHKV
DAPSGTALSMGEHIAKTLGRDLKTHGVFAREGITGERKRDEIGFATIRAGDVVGEHSVWFADEGERVEIAHKASSRMTFA
NGAVRAAKWLNTKQNGLFDMTDVLDLNNL

Sequences:

>Translated_269_residues
MTLKIGIVGAGGRMGRNLITAVQNAEGVELGAAFERKGSSLVGADAGEVAGIGATGVKISDDLNQNTNFDVLIDFTRPEG
TLEHIKFCVANGKKMVIGTTGFDDAGKQAIQTAAEQISIVFASNYSVGVNLVFKLLEKAAKVMGDYCDIEVIEAHHRHKV
DAPSGTALSMGEHIAKTLGRDLKTHGVFAREGITGERKRDEIGFATIRAGDVVGEHSVWFADEGERVEIAHKASSRMTFA
NGAVRAAKWLNTKQNGLFDMTDVLDLNNL
>Mature_268_residues
TLKIGIVGAGGRMGRNLITAVQNAEGVELGAAFERKGSSLVGADAGEVAGIGATGVKISDDLNQNTNFDVLIDFTRPEGT
LEHIKFCVANGKKMVIGTTGFDDAGKQAIQTAAEQISIVFASNYSVGVNLVFKLLEKAAKVMGDYCDIEVIEAHHRHKVD
APSGTALSMGEHIAKTLGRDLKTHGVFAREGITGERKRDEIGFATIRAGDVVGEHSVWFADEGERVEIAHKASSRMTFAN
GAVRAAKWLNTKQNGLFDMTDVLDLNNL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=268, Percent_Identity=69.4029850746269, Blast_Score=362, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_ACTP2 (A3N048)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053389.1
- ProteinModelPortal:   A3N048
- SMR:   A3N048
- STRING:   A3N048
- GeneID:   4849484
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0684
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- PhylomeDB:   A3N048
- ProtClustDB:   PRK00048
- BioCyc:   APLE416269:APL_0684-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28701; Mature: 28570

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKIGIVGAGGRMGRNLITAVQNAEGVELGAAFERKGSSLVGADAGEVAGIGATGVKIS
CEEEEEEEECCCHHCHHHHHHHCCCCCCEECHHHHHCCCEEECCCCCCCCCCCCCCEEEC
DDLNQNTNFDVLIDFTRPEGTLEHIKFCVANGKKMVIGTTGFDDAGKQAIQTAAEQISIV
CCCCCCCCEEEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHEEEE
FASNYSVGVNLVFKLLEKAAKVMGDYCDIEVIEAHHRHKVDAPSGTALSMGEHIAKTLGR
EECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECHHCCCCCCCCCCCHHHHHHHHHHHCC
DLKTHGVFAREGITGERKRDEIGFATIRAGDVVGEHSVWFADEGERVEIAHKASSRMTFA
CHHHCCEEEECCCCCCCCCCCCCEEEEEECCEECCCCEEECCCCCEEEEEECCCCCEEEC
NGAVRAAKWLNTKQNGLFDMTDVLDLNNL
CCHHHHHHHHCCCCCCCCCHHHHHCCCCC
>Mature Secondary Structure 
TLKIGIVGAGGRMGRNLITAVQNAEGVELGAAFERKGSSLVGADAGEVAGIGATGVKIS
EEEEEEEECCCHHCHHHHHHHCCCCCCEECHHHHHCCCEEECCCCCCCCCCCCCCEEEC
DDLNQNTNFDVLIDFTRPEGTLEHIKFCVANGKKMVIGTTGFDDAGKQAIQTAAEQISIV
CCCCCCCCEEEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHEEEE
FASNYSVGVNLVFKLLEKAAKVMGDYCDIEVIEAHHRHKVDAPSGTALSMGEHIAKTLGR
EECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECHHCCCCCCCCCCCHHHHHHHHHHHCC
DLKTHGVFAREGITGERKRDEIGFATIRAGDVVGEHSVWFADEGERVEIAHKASSRMTFA
CHHHCCEEEECCCCCCCCCCCCCEEEEEECCEECCCCEEECCCCCEEEEEECCCCCEEEC
NGAVRAAKWLNTKQNGLFDMTDVLDLNNL
CCHHHHHHHHCCCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA