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The map label for this gene is efp

Identifier: 126208158

GI number: 126208158

Start: 773923

End: 774489

Strand: Direct

Name: efp

Synonym: APL_0678

Alternate gene names: 126208158

Gene position: 773923-774489 (Clockwise)

Preceding gene: 126208155

Following gene: 126208159

Centisome position: 34.03

GC content: 42.33

Gene sequence:

>567_bases
ATGGCTAGTTACAGCACTAATGACTTCAAACCGGGTTTAAAATTTATTCAAGATGGCGAACCTTGCGTAATCGTTGAAAA
TGAATTCGTAAAACCGGGTAAAGGTCAAGCGTTTACCCGTACCAAAATCCGTAAATTAATCTCTGGTAAAGTATTAGAGA
TCAACTTCAAATCAGGTACTTCCGTTGAAGCGGCGGATGTTGTTGATTACAACTACACTTACTCATATAAAGACGAAGAT
TTCTGGTACTTTATGCACCCTGAAACGTTCGAACAAATCTCTGTAGATGAAAAAGCATTAGGCGACAACGACAAATGGTT
AGTTGACCAAGCCGAATGTATCATCACATTATGGAACGGTTCCGCAATTTCTGTAACTCCACCGAACTTCGTTGAATTAG
AAGTGGTTGAAACCGATCCGGGCTTAAAAGGCGACACGGCAGGTACCGGCGGTAAACCGGCAACATTAAGCACCGGTGCG
GTTGTTCGTGTACCGTTATTCGTACAAATCGGCGAAGTAATCCGTGTTGATACTCGTTCAGGCGAATACGTTTCACGTGT
GAAATAA

Upstream 100 bases:

>100_bases
AGAGATCTTTCGCTAATTGCTGTATTATATGGGTCTTTTTGACAAATCCAATAGCGGATTTTTAAATTTTGTTAATCTCT
TGTTAATTATTGAGGAAAAA

Downstream 100 bases:

>100_bases
TCTAATTTTATAAGAATTTAAGCGGTCGAATTTCTTGCAAATTTTGCAAACAATTCGACCGCTTTTTTATTTCTCTCTGT
TTGTCGCTTTATGAAATTTG

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MASYSTNDFKPGLKFIQDGEPCVIVENEFVKPGKGQAFTRTKIRKLISGKVLEINFKSGTSVEAADVVDYNYTYSYKDED
FWYFMHPETFEQISVDEKALGDNDKWLVDQAECIITLWNGSAISVTPPNFVELEVVETDPGLKGDTAGTGGKPATLSTGA
VVRVPLFVQIGEVIRVDTRSGEYVSRVK

Sequences:

>Translated_188_residues
MASYSTNDFKPGLKFIQDGEPCVIVENEFVKPGKGQAFTRTKIRKLISGKVLEINFKSGTSVEAADVVDYNYTYSYKDED
FWYFMHPETFEQISVDEKALGDNDKWLVDQAECIITLWNGSAISVTPPNFVELEVVETDPGLKGDTAGTGGKPATLSTGA
VVRVPLFVQIGEVIRVDTRSGEYVSRVK
>Mature_187_residues
ASYSTNDFKPGLKFIQDGEPCVIVENEFVKPGKGQAFTRTKIRKLISGKVLEINFKSGTSVEAADVVDYNYTYSYKDEDF
WYFMHPETFEQISVDEKALGDNDKWLVDQAECIITLWNGSAISVTPPNFVELEVVETDPGLKGDTAGTGGKPATLSTGAV
VRVPLFVQIGEVIRVDTRSGEYVSRVK

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=188, Percent_Identity=72.8723404255319, Blast_Score=291, Evalue=2e-80,
Organism=Escherichia coli, GI87082061, Length=187, Percent_Identity=29.9465240641711, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_ACTP2 (A3N042)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053383.1
- ProteinModelPortal:   A3N042
- SMR:   A3N042
- STRING:   A3N042
- GeneID:   4849216
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0678
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   A3N042
- ProtClustDB:   PRK00529
- BioCyc:   APLE416269:APL_0678-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20817; Mature: 20685

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASYSTNDFKPGLKFIQDGEPCVIVENEFVKPGKGQAFTRTKIRKLISGKVLEINFKSGT
CCCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCCCEEHHHHHHHHHCCCEEEEEECCCC
SVEAADVVDYNYTYSYKDEDFWYFMHPETFEQISVDEKALGDNDKWLVDQAECIITLWNG
CEEEEEEEECCCEEEECCCCEEEEECCCCHHHCCCCHHHCCCCCEEEEECCEEEEEEECC
SAISVTPPNFVELEVVETDPGLKGDTAGTGGKPATLSTGAVVRVPLFVQIGEVIRVDTRS
CEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCEECCCCEEEEEEEEEECCEEEEECCC
GEYVSRVK
CCEEECCC
>Mature Secondary Structure 
ASYSTNDFKPGLKFIQDGEPCVIVENEFVKPGKGQAFTRTKIRKLISGKVLEINFKSGT
CCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCCCEEHHHHHHHHHCCCEEEEEECCCC
SVEAADVVDYNYTYSYKDEDFWYFMHPETFEQISVDEKALGDNDKWLVDQAECIITLWNG
CEEEEEEEECCCEEEECCCCEEEEECCCCHHHCCCCHHHCCCCCEEEEECCEEEEEEECC
SAISVTPPNFVELEVVETDPGLKGDTAGTGGKPATLSTGAVVRVPLFVQIGEVIRVDTRS
CEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCEECCCCEEEEEEEEEECCEEEEECCC
GEYVSRVK
CCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA