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The map label for this gene is asnC

Identifier: 126208155

GI number: 126208155

Start: 770614

End: 772017

Strand: Direct

Name: asnC

Synonym: APL_0675

Alternate gene names: 126208155

Gene position: 770614-772017 (Clockwise)

Preceding gene: 126208150

Following gene: 126208158

Centisome position: 33.88

GC content: 44.44

Gene sequence:

>1404_bases
ATGTCTAAATTTCCAACAGTTTCGGAAATCCTATCGGGCAAAGTAGCGGTAGGCGAAGAAGTTGCGGTACGCGGTTGGGT
ACGTACCCGCCGTGACTCAAAAGCAGGTTTATCATTTTTAGCCGTTTATGACGGTTCTTGTTTCGATCCGATCCAATCGA
TCATTAATAACGATTTAGCAAATTATAACGATGAAGTATTACGTTTAACCGCAGGTTGTTCCGTTATCGTCACCGGTAAA
GTGGTTGAATCGCCGGCAGAAGGTCAAGCGGTCGAATTACACGCAACGCACGTGGAAGTGGTCGGTTGGGTTGAAGATCC
GGATACTTATCCGATGGCGGCAAAACGTCACTCAATCGAATATTTACGTGAAGTTGCGCACTTACGTCCTCGTACCAACT
TAATCGGTGCGGTTGCGCGTGTTCGTCACTGCTTAGCACAAGCGATTCACCGTTTCTTTAACGAGCAAGGTTTCTACTGG
GTAGCGACTCCGCTTATTACTGCATCGGATACGGAAGGCGCGGGCGAAATGTTCCGTGTTTCAACATTAGATTTAGAAAA
CTTACCGCGCACTGAGGAAGGCAAAGTCGATTTTAGCCAAGACTTTTTCGGTAAAGAGTCTTTCTTAACCGTATCAGGTC
AGTTAAACGGCGAAACTTACGCTTGTGCATTAAGCAAAGTTTATACGTTCGGCCCGACATTCCGTGCGGAAAACTCAAAT
ACCACTCGCCACTTAGCGGAATTCTGGATGGTTGAGCCTGAATTTGCATTCGCAACCTTAGCGGACAATGCAAAATTAGC
GGAAGATATGCTGAAATATGTGTTTAAAGCGGTACTTGAAGAGCGTAAAGACGATATGCAATTCTTCGCAAAACACATTG
ATAAAGATGTCATTACTCGCTTAGAAAACTTTATCGCTGCACCGTTTGCGCAAGTTGATTACACCGATGCAATTGAAATC
TTATTAAAATCAGGTAAAGAATTTGAATTCCCGGTTTCTTGGGGTATCGATCTTTCTTCCGAACACGAGCGTTTCTTAGC
GGAAGAATATTTCAAATCGCCGGTGGTTGTGAAAAACTATCCGAAAGACATTAAAGCATTCTATATGCGTTTAAACGATG
ACGGTAAAACCGTGGCGGCAATGGACGTATTAGCACCGGGAATCGGTGAGATTATCGGCGGTTCACAGCGTGAAGAACGT
TTAGACGTATTAGACACACGTATGGTTGAAATGGGCTTAAATCCGGAAGATTACTGGTGGTACCGCGATTTACGTAAATA
CGGTACGGTTCCGCACTCCGGCTTCGGCTTAGGTTTTGAACGTTTAATCGTTTATGTAACCGGTTTACAAAATATCCGTG
AAGTAATTCCGTTCCCACGTGCACCGCGTAATGCGAATTTCTAA

Upstream 100 bases:

>100_bases
ATCCAAAAAAATCGACAATTTCCTTTATTTCCTTACTTATTCTTGTAAAATACCGAACGATTATTTTCTGTAAAACTCAC
CATAAAGATTGAGGTATTCA

Downstream 100 bases:

>100_bases
TCGAAACTAACGAAAAAGGGCGAATAAGATTATTCGCCCTTTTGCATATAAGCGGTCAAAATTTGCAAAAAATCAGCAAA
ATTTAACCGCTTGTTGAACT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MSKFPTVSEILSGKVAVGEEVAVRGWVRTRRDSKAGLSFLAVYDGSCFDPIQSIINNDLANYNDEVLRLTAGCSVIVTGK
VVESPAEGQAVELHATHVEVVGWVEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHCLAQAIHRFFNEQGFYW
VATPLITASDTEGAGEMFRVSTLDLENLPRTEEGKVDFSQDFFGKESFLTVSGQLNGETYACALSKVYTFGPTFRAENSN
TTRHLAEFWMVEPEFAFATLADNAKLAEDMLKYVFKAVLEERKDDMQFFAKHIDKDVITRLENFIAAPFAQVDYTDAIEI
LLKSGKEFEFPVSWGIDLSSEHERFLAEEYFKSPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREER
LDVLDTRMVEMGLNPEDYWWYRDLRKYGTVPHSGFGLGFERLIVYVTGLQNIREVIPFPRAPRNANF

Sequences:

>Translated_467_residues
MSKFPTVSEILSGKVAVGEEVAVRGWVRTRRDSKAGLSFLAVYDGSCFDPIQSIINNDLANYNDEVLRLTAGCSVIVTGK
VVESPAEGQAVELHATHVEVVGWVEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHCLAQAIHRFFNEQGFYW
VATPLITASDTEGAGEMFRVSTLDLENLPRTEEGKVDFSQDFFGKESFLTVSGQLNGETYACALSKVYTFGPTFRAENSN
TTRHLAEFWMVEPEFAFATLADNAKLAEDMLKYVFKAVLEERKDDMQFFAKHIDKDVITRLENFIAAPFAQVDYTDAIEI
LLKSGKEFEFPVSWGIDLSSEHERFLAEEYFKSPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREER
LDVLDTRMVEMGLNPEDYWWYRDLRKYGTVPHSGFGLGFERLIVYVTGLQNIREVIPFPRAPRNANF
>Mature_466_residues
SKFPTVSEILSGKVAVGEEVAVRGWVRTRRDSKAGLSFLAVYDGSCFDPIQSIINNDLANYNDEVLRLTAGCSVIVTGKV
VESPAEGQAVELHATHVEVVGWVEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHCLAQAIHRFFNEQGFYWV
ATPLITASDTEGAGEMFRVSTLDLENLPRTEEGKVDFSQDFFGKESFLTVSGQLNGETYACALSKVYTFGPTFRAENSNT
TRHLAEFWMVEPEFAFATLADNAKLAEDMLKYVFKAVLEERKDDMQFFAKHIDKDVITRLENFIAAPFAQVDYTDAIEIL
LKSGKEFEFPVSWGIDLSSEHERFLAEEYFKSPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDTRMVEMGLNPEDYWWYRDLRKYGTVPHSGFGLGFERLIVYVTGLQNIREVIPFPRAPRNANF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=464, Percent_Identity=42.0258620689655, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI4758762, Length=461, Percent_Identity=29.5010845986985, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI45439306, Length=425, Percent_Identity=28, Blast_Score=128, Evalue=1e-29,
Organism=Escherichia coli, GI1787161, Length=467, Percent_Identity=82.2269807280514, Blast_Score=817, Evalue=0.0,
Organism=Escherichia coli, GI1788173, Length=104, Percent_Identity=35.5769230769231, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71984122, Length=452, Percent_Identity=31.4159292035398, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17556372, Length=427, Percent_Identity=30.2107728337237, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17551876, Length=480, Percent_Identity=27.0833333333333, Blast_Score=121, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6319872, Length=471, Percent_Identity=37.5796178343949, Blast_Score=284, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6321807, Length=461, Percent_Identity=32.3210412147505, Blast_Score=212, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6323011, Length=492, Percent_Identity=27.6422764227642, Blast_Score=124, Evalue=3e-29,
Organism=Drosophila melanogaster, GI19922416, Length=469, Percent_Identity=35.6076759061834, Blast_Score=281, Evalue=8e-76,
Organism=Drosophila melanogaster, GI19921528, Length=462, Percent_Identity=29.8701298701299, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI17136276, Length=490, Percent_Identity=26.3265306122449, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_ACTP2 (A3N039)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053380.1
- ProteinModelPortal:   A3N039
- SMR:   A3N039
- STRING:   A3N039
- GeneID:   4850404
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0675
- eggNOG:   COG0017
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- PhylomeDB:   A3N039
- ProtClustDB:   PRK03932
- BioCyc:   APLE416269:APL_0675-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 52727; Mature: 52596

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKFPTVSEILSGKVAVGEEVAVRGWVRTRRDSKAGLSFLAVYDGSCFDPIQSIINNDLA
CCCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHCCHHC
NYNDEVLRLTAGCSVIVTGKVVESPAEGQAVELHATHVEVVGWVEDPDTYPMAAKRHSIE
CCCCCEEEEECCCEEEEECHHHCCCCCCCEEEEEEEEEEEEEEECCCCCCCCHHHHHHHH
YLREVAHLRPRTNLIGAVARVRHCLAQAIHRFFNEQGFYWVATPLITASDTEGAGEMFRV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECEEEECCCCCCCCEEEE
STLDLENLPRTEEGKVDFSQDFFGKESFLTVSGQLNGETYACALSKVYTFGPTFRAENSN
EEECHHCCCCCCCCCCCCCHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEECCCCC
TTRHLAEFWMVEPEFAFATLADNAKLAEDMLKYVFKAVLEERKDDMQFFAKHIDKDVITR
HHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
LENFIAAPFAQVDYTDAIEILLKSGKEFEFPVSWGIDLSSEHERFLAEEYFKSPVVVKNY
HHHHHHCCCHHCCHHHHHHHHHHCCCCEECCEEECCCCCCHHHHHHHHHHHCCCEEECCC
PKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDTRMVEMGLNPEDYWW
CHHHEEHEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHH
YRDLRKYGTVPHSGFGLGFERLIVYVTGLQNIREVIPFPRAPRNANF
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SKFPTVSEILSGKVAVGEEVAVRGWVRTRRDSKAGLSFLAVYDGSCFDPIQSIINNDLA
CCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHCCHHC
NYNDEVLRLTAGCSVIVTGKVVESPAEGQAVELHATHVEVVGWVEDPDTYPMAAKRHSIE
CCCCCEEEEECCCEEEEECHHHCCCCCCCEEEEEEEEEEEEEEECCCCCCCCHHHHHHHH
YLREVAHLRPRTNLIGAVARVRHCLAQAIHRFFNEQGFYWVATPLITASDTEGAGEMFRV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECEEEECCCCCCCCEEEE
STLDLENLPRTEEGKVDFSQDFFGKESFLTVSGQLNGETYACALSKVYTFGPTFRAENSN
EEECHHCCCCCCCCCCCCCHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEECCCCC
TTRHLAEFWMVEPEFAFATLADNAKLAEDMLKYVFKAVLEERKDDMQFFAKHIDKDVITR
HHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
LENFIAAPFAQVDYTDAIEILLKSGKEFEFPVSWGIDLSSEHERFLAEEYFKSPVVVKNY
HHHHHHCCCHHCCHHHHHHHHHHCCCCEECCEEECCCCCCHHHHHHHHHHHCCCEEECCC
PKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDTRMVEMGLNPEDYWW
CHHHEEHEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHH
YRDLRKYGTVPHSGFGLGFERLIVYVTGLQNIREVIPFPRAPRNANF
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA