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The map label for this gene is aspC [H]

Identifier: 126208142

GI number: 126208142

Start: 755686

End: 756882

Strand: Direct

Name: aspC [H]

Synonym: APL_0662

Alternate gene names: 126208142

Gene position: 755686-756882 (Clockwise)

Preceding gene: 126208141

Following gene: 126208148

Centisome position: 33.22

GC content: 43.78

Gene sequence:

>1197_bases
ATGTCAATGTTCAACCACATTCAGGCTGCTCCGGCAGATCCGATTTTAGGTTTAGGCGAAGCGTTTAAAGCGGAACAACG
TGCAGGGAAAATCAACCTCGGTATCGGTGTTTATATGAATGCGGAAGGTAAAACACCTATCGTGAAAGCGGTAAAAAAAG
CGGAAGCGTTATTATTAGAACAAGAAACGAATAAAAACTACCTCACGATTGACGGTGTACAAGCATTTAACGCTTATACG
CAAGAACTTTTATTCGGTAAAGGGGCGGAAATTATCGCTTCAGGTCGTGCAAAAACCGCACAAAGCTTAGGTGGTACGGG
CGCATTACGTATTGCGGCGGAATTTATCAAACGCCAAACGTCAGCAAAAAATATCTGGATTTCCAACCCGACTTGGCCGA
ACCACAATGCGATTGCCGAAGCGGTCGGTTTAAATGTCAAAGGCTATCGTTATTACAACCCTGAAACACACGGTTTAGAT
TGGGATAACTTGCTTGCCGATTTAAGCCAAGCGGAAGCCGGTGATGTGGTGTTATTACACGGTTGCTGTCATAACCCGAC
CGGTATCGACCCTACACCGGAACAATGGGACGCATTAGCGAAACTTTCTGCGGAAAAAGGTTGGTTACCGTTATTTGACT
TTGCTTACCAAGGTTTCGGTAACGGTTTAGGCCAAGACGCATACGGCTTACGTGCGTTTGTGAAAAACCACAAAGAATTA
TTAATCGCAAGTTCATACTCAAAAAACTTCGGTTTATATAACGAGCGTGTCGGTGCATTTACCTTAGTGGCGGAAAATGC
GGATGTGGCAAATAAAGCATTCACCCAAATTAAATCAATTATTCGTGTGCTTTACTCTAACCCGGCAGCACACGGTGCAA
ATGCGGTTGCTCGTGTATTAGGCGATGAAACGTTACGTGCGGAATGGGTCGCGGAATTAGATGAAATGCGTGATCGCATT
AAAGGTATGCGTAACCGTATGGTGCAATTATTAAAAGAGAAAGGAGCAAAACAAGATTTCGATTTTATTGCAAAACAAAA
CGGTATGTTCTCATTTAGCGGCTTAACACCGGAACAAGTGGATCGCCTACGTGAAGAGTTCGCAATTTATGCGGTACGTT
CAGGTCGTATCAATGTGGCAGGTATTACCGACCAAAATATTGATGCACTTTGCGAAGCGATTGTAAAAGTGCTTTAG

Upstream 100 bases:

>100_bases
CAAAAAATTTTCAAAAATAGACCGCTTTTCTATTGCTAAAATAGCTAATGGGTTGTATAAATATTTCTAATTTCAAACAC
AACTTTATAGAGGACACATT

Downstream 100 bases:

>100_bases
TCACTATTTTGTAAAACCACGGACTACACTGAATACACGGAAAATTTATTCTGTGAACACTATGTAGTTCGTGGTTATTT
TTATGTATAGCTTTAGGTAA

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSMFNHIQAAPADPILGLGEAFKAEQRAGKINLGIGVYMNAEGKTPIVKAVKKAEALLLEQETNKNYLTIDGVQAFNAYT
QELLFGKGAEIIASGRAKTAQSLGGTGALRIAAEFIKRQTSAKNIWISNPTWPNHNAIAEAVGLNVKGYRYYNPETHGLD
WDNLLADLSQAEAGDVVLLHGCCHNPTGIDPTPEQWDALAKLSAEKGWLPLFDFAYQGFGNGLGQDAYGLRAFVKNHKEL
LIASSYSKNFGLYNERVGAFTLVAENADVANKAFTQIKSIIRVLYSNPAAHGANAVARVLGDETLRAEWVAELDEMRDRI
KGMRNRMVQLLKEKGAKQDFDFIAKQNGMFSFSGLTPEQVDRLREEFAIYAVRSGRINVAGITDQNIDALCEAIVKVL

Sequences:

>Translated_398_residues
MSMFNHIQAAPADPILGLGEAFKAEQRAGKINLGIGVYMNAEGKTPIVKAVKKAEALLLEQETNKNYLTIDGVQAFNAYT
QELLFGKGAEIIASGRAKTAQSLGGTGALRIAAEFIKRQTSAKNIWISNPTWPNHNAIAEAVGLNVKGYRYYNPETHGLD
WDNLLADLSQAEAGDVVLLHGCCHNPTGIDPTPEQWDALAKLSAEKGWLPLFDFAYQGFGNGLGQDAYGLRAFVKNHKEL
LIASSYSKNFGLYNERVGAFTLVAENADVANKAFTQIKSIIRVLYSNPAAHGANAVARVLGDETLRAEWVAELDEMRDRI
KGMRNRMVQLLKEKGAKQDFDFIAKQNGMFSFSGLTPEQVDRLREEFAIYAVRSGRINVAGITDQNIDALCEAIVKVL
>Mature_397_residues
SMFNHIQAAPADPILGLGEAFKAEQRAGKINLGIGVYMNAEGKTPIVKAVKKAEALLLEQETNKNYLTIDGVQAFNAYTQ
ELLFGKGAEIIASGRAKTAQSLGGTGALRIAAEFIKRQTSAKNIWISNPTWPNHNAIAEAVGLNVKGYRYYNPETHGLDW
DNLLADLSQAEAGDVVLLHGCCHNPTGIDPTPEQWDALAKLSAEKGWLPLFDFAYQGFGNGLGQDAYGLRAFVKNHKELL
IASSYSKNFGLYNERVGAFTLVAENADVANKAFTQIKSIIRVLYSNPAAHGANAVARVLGDETLRAEWVAELDEMRDRIK
GMRNRMVQLLKEKGAKQDFDFIAKQNGMFSFSGLTPEQVDRLREEFAIYAVRSGRINVAGITDQNIDALCEAIVKVL

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=396, Percent_Identity=43.4343434343434, Blast_Score=364, Evalue=1e-101,
Organism=Homo sapiens, GI4504067, Length=408, Percent_Identity=39.4607843137255, Blast_Score=301, Evalue=8e-82,
Organism=Homo sapiens, GI117414139, Length=381, Percent_Identity=28.0839895013123, Blast_Score=156, Evalue=3e-38,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=63.8888888888889, Blast_Score=538, Evalue=1e-154,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=42.5692695214106, Blast_Score=351, Evalue=5e-98,
Organism=Caenorhabditis elegans, GI71981858, Length=395, Percent_Identity=42.2784810126582, Blast_Score=352, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI25147133, Length=397, Percent_Identity=40.5541561712846, Blast_Score=343, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI17569539, Length=397, Percent_Identity=37.0277078085642, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17569537, Length=396, Percent_Identity=31.0606060606061, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI25147136, Length=213, Percent_Identity=39.4366197183099, Blast_Score=181, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI17550384, Length=263, Percent_Identity=34.6007604562738, Blast_Score=174, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6323055, Length=406, Percent_Identity=38.423645320197, Blast_Score=291, Evalue=9e-80,
Organism=Saccharomyces cerevisiae, GI6322743, Length=430, Percent_Identity=34.1860465116279, Blast_Score=244, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24580970, Length=398, Percent_Identity=41.4572864321608, Blast_Score=331, Evalue=6e-91,
Organism=Drosophila melanogaster, GI24580972, Length=398, Percent_Identity=41.4572864321608, Blast_Score=330, Evalue=7e-91,
Organism=Drosophila melanogaster, GI19920542, Length=389, Percent_Identity=41.9023136246787, Blast_Score=325, Evalue=3e-89,
Organism=Drosophila melanogaster, GI24654046, Length=397, Percent_Identity=39.5465994962217, Blast_Score=305, Evalue=5e-83,
Organism=Drosophila melanogaster, GI19922362, Length=397, Percent_Identity=39.5465994962217, Blast_Score=305, Evalue=5e-83,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43580; Mature: 43449

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMFNHIQAAPADPILGLGEAFKAEQRAGKINLGIGVYMNAEGKTPIVKAVKKAEALLLE
CCHHHHCCCCCCCCCCCCHHHHHHHHHCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
QETNKNYLTIDGVQAFNAYTQELLFGKGAEIIASGRAKTAQSLGGTGALRIAAEFIKRQT
HCCCCCEEEECCHHHHHHHHHHHHHCCCCHHEECCCHHHHHHCCCCHHHHHHHHHHHHHC
SAKNIWISNPTWPNHNAIAEAVGLNVKGYRYYNPETHGLDWDNLLADLSQAEAGDVVLLH
CCCEEEECCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEE
GCCHNPTGIDPTPEQWDALAKLSAEKGWLPLFDFAYQGFGNGLGQDAYGLRAFVKNHKEL
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHE
LIASSYSKNFGLYNERVGAFTLVAENADVANKAFTQIKSIIRVLYSNPAAHGANAVARVL
EEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
GDETLRAEWVAELDEMRDRIKGMRNRMVQLLKEKGAKQDFDFIAKQNGMFSFSGLTPEQV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEECCCCHHHH
DRLREEFAIYAVRSGRINVAGITDQNIDALCEAIVKVL
HHHHHHHEEEEEECCEEEEEECCCCCHHHHHHHHHHHC
>Mature Secondary Structure 
SMFNHIQAAPADPILGLGEAFKAEQRAGKINLGIGVYMNAEGKTPIVKAVKKAEALLLE
CHHHHCCCCCCCCCCCCHHHHHHHHHCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
QETNKNYLTIDGVQAFNAYTQELLFGKGAEIIASGRAKTAQSLGGTGALRIAAEFIKRQT
HCCCCCEEEECCHHHHHHHHHHHHHCCCCHHEECCCHHHHHHCCCCHHHHHHHHHHHHHC
SAKNIWISNPTWPNHNAIAEAVGLNVKGYRYYNPETHGLDWDNLLADLSQAEAGDVVLLH
CCCEEEECCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEE
GCCHNPTGIDPTPEQWDALAKLSAEKGWLPLFDFAYQGFGNGLGQDAYGLRAFVKNHKEL
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHE
LIASSYSKNFGLYNERVGAFTLVAENADVANKAFTQIKSIIRVLYSNPAAHGANAVARVL
EEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
GDETLRAEWVAELDEMRDRIKGMRNRMVQLLKEKGAKQDFDFIAKQNGMFSFSGLTPEQV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEECCCCHHHH
DRLREEFAIYAVRSGRINVAGITDQNIDALCEAIVKVL
HHHHHHHEEEEEECCEEEEEECCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]