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The map label for this gene is 126208020

Identifier: 126208020

GI number: 126208020

Start: 608882

End: 609826

Strand: Direct

Name: 126208020

Synonym: APL_0538

Alternate gene names: NA

Gene position: 608882-609826 (Clockwise)

Preceding gene: 126208019

Following gene: 126208021

Centisome position: 26.77

GC content: 41.59

Gene sequence:

>945_bases
ATGAAATATGTAAAAAAATTAGCTTTTCTGACCGCTTGTAGTTTAGCGGTACAAGCTCACGCCGGCGAGAAAATGACCGT
CTTATTAGATTGGTTCGTTAATCCGGATCACGCTGCGATTATTGTGGCGCAACAGAAAGGTTATTTTAAGCAAAACGGCT
TGGAAGTTGAACTAGTAGAGCCGGCGGATCCGTCTATGCCGCCCAAACCGGTTGCGGCAGGGCAGGCGGATATTGCGGTG
GATTATCAGCCGCAATTACAACTACAAGTTGATCAAGGTTTGCCGTTGGTCCGTTTCGGTACGCTGGTTCCTACACCCTT
GAATAGCTTAATTGTTTTGAAAAACGGCTCGGTAAAAAATATCGCCGATTTAAAAGGTAAGAAAATCGGTTATTCGGTAA
GCGGTTTTGAAGATGCATTACTGAATACCATGCTGGCGAATTCAGGTGTCTCAGCGAAAGATGTGGAATTGGTTAATGTA
AATTGGTCGCTTTCTCCAAGTTTGATTAGCGGTCAAGTTGATGCGATTATCGGCGGCTTTCGTAATTTTGAATTAAACCA
GATGCAGTTGGAAAAACAGGAAGGTAAAGCGTTCTTTGCGGAAGATTTCGGCGTACCGGTTTATGAAGAATTAATTCTTG
TCGCGCATAAAGATAAAGCGAACGATGCAAAATTTTCCGCATTTTTGACCTCTTTAGAACAAGCTACGCAATATTTAAAA
CAGTCGCCGGATGAAGCGTGGAATAGTTTTGTTAGTTATAAACCGAAAGAATTGGATACGGCGTTAAATCGTCTTGCATG
GCGTGATACGCTGCCGAAATTAGCAGATGAACCACGCAAATTAGATCGTGAAAAATATCAAAAATTCAGTGAGTTTATGC
AAAAGAACGATTTGACGAAAACTGTACCGGAGTTAAAAGTATATACGGTTGAATTGAAACCATAG

Upstream 100 bases:

>100_bases
AAACTCCAAGAAATCTTTACTACTGCTACACGTATGGAAGTCGCATTTTGGCAAATGGGGCTTGATAAAACAATGTAATC
TTTCTTAAAAGGAGCAAATG

Downstream 100 bases:

>100_bases
AGAAGACTTACTAGAGAGAAATATATGGAAAAGATAGCACAGGCTTTAACTGTCGCCGGTTCGGATAGCGGTGGCGGAGC
GGGGATTCAGGCGGATTTCA

Product: putative ABC transporter substrate-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MKYVKKLAFLTACSLAVQAHAGEKMTVLLDWFVNPDHAAIIVAQQKGYFKQNGLEVELVEPADPSMPPKPVAAGQADIAV
DYQPQLQLQVDQGLPLVRFGTLVPTPLNSLIVLKNGSVKNIADLKGKKIGYSVSGFEDALLNTMLANSGVSAKDVELVNV
NWSLSPSLISGQVDAIIGGFRNFELNQMQLEKQEGKAFFAEDFGVPVYEELILVAHKDKANDAKFSAFLTSLEQATQYLK
QSPDEAWNSFVSYKPKELDTALNRLAWRDTLPKLADEPRKLDREKYQKFSEFMQKNDLTKTVPELKVYTVELKP

Sequences:

>Translated_314_residues
MKYVKKLAFLTACSLAVQAHAGEKMTVLLDWFVNPDHAAIIVAQQKGYFKQNGLEVELVEPADPSMPPKPVAAGQADIAV
DYQPQLQLQVDQGLPLVRFGTLVPTPLNSLIVLKNGSVKNIADLKGKKIGYSVSGFEDALLNTMLANSGVSAKDVELVNV
NWSLSPSLISGQVDAIIGGFRNFELNQMQLEKQEGKAFFAEDFGVPVYEELILVAHKDKANDAKFSAFLTSLEQATQYLK
QSPDEAWNSFVSYKPKELDTALNRLAWRDTLPKLADEPRKLDREKYQKFSEFMQKNDLTKTVPELKVYTVELKP
>Mature_314_residues
MKYVKKLAFLTACSLAVQAHAGEKMTVLLDWFVNPDHAAIIVAQQKGYFKQNGLEVELVEPADPSMPPKPVAAGQADIAV
DYQPQLQLQVDQGLPLVRFGTLVPTPLNSLIVLKNGSVKNIADLKGKKIGYSVSGFEDALLNTMLANSGVSAKDVELVNV
NWSLSPSLISGQVDAIIGGFRNFELNQMQLEKQEGKAFFAEDFGVPVYEELILVAHKDKANDAKFSAFLTSLEQATQYLK
QSPDEAWNSFVSYKPKELDTALNRLAWRDTLPKLADEPRKLDREKYQKFSEFMQKNDLTKTVPELKVYTVELKP

Specific function: Probably involved in thiamine biosynthesis [H]

COG id: COG0715

COG function: function code P; ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NMT1 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319957, Length=247, Percent_Identity=28.3400809716599, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6323997, Length=247, Percent_Identity=28.3400809716599, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6321050, Length=247, Percent_Identity=28.3400809716599, Blast_Score=109, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6322616, Length=247, Percent_Identity=27.9352226720648, Blast_Score=107, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 34921; Mature: 34921

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYVKKLAFLTACSLAVQAHAGEKMTVLLDWFVNPDHAAIIVAQQKGYFKQNGLEVELVE
CHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEEECCCCHHHCCEEEEEEC
PADPSMPPKPVAAGQADIAVDYQPQLQLQVDQGLPLVRFGTLVPTPLNSLIVLKNGSVKN
CCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCEEEECCCCCCCCCCEEEEECCCCCC
IADLKGKKIGYSVSGFEDALLNTMLANSGVSAKDVELVNVNWSLSPSLISGQVDAIIGGF
HHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHCCCHHHHHCCC
RNFELNQMQLEKQEGKAFFAEDFGVPVYEELILVAHKDKANDAKFSAFLTSLEQATQYLK
CCCCCHHHHHHHHCCCEEEEHHCCCCHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
QSPDEAWNSFVSYKPKELDTALNRLAWRDTLPKLADEPRKLDREKYQKFSEFMQKNDLTK
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHH
TVPELKVYTVELKP
CCCCEEEEEEEECC
>Mature Secondary Structure
MKYVKKLAFLTACSLAVQAHAGEKMTVLLDWFVNPDHAAIIVAQQKGYFKQNGLEVELVE
CHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEEECCCCHHHCCEEEEEEC
PADPSMPPKPVAAGQADIAVDYQPQLQLQVDQGLPLVRFGTLVPTPLNSLIVLKNGSVKN
CCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCEEEECCCCCCCCCCEEEEECCCCCC
IADLKGKKIGYSVSGFEDALLNTMLANSGVSAKDVELVNVNWSLSPSLISGQVDAIIGGF
HHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHCCCHHHHHCCC
RNFELNQMQLEKQEGKAFFAEDFGVPVYEELILVAHKDKANDAKFSAFLTSLEQATQYLK
CCCCCHHHHHHHHCCCEEEEHHCCCCHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
QSPDEAWNSFVSYKPKELDTALNRLAWRDTLPKLADEPRKLDREKYQKFSEFMQKNDLTK
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHH
TVPELKVYTVELKP
CCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]