Click here to switch to the map view.

The map label for this gene is lctP [C]

Identifier: 126207931

GI number: 126207931

Start: 513511

End: 515106

Strand: Reverse

Name: lctP [C]

Synonym: APL_0447

Alternate gene names: 126207931

Gene position: 515106-513511 (Counterclockwise)

Preceding gene: 126207932

Following gene: 126207930

Centisome position: 22.65

GC content: 41.17

Gene sequence:

>1596_bases
ATGGCGTTATTCCTTAGTATTTTCCCAATCGTTTTACTCATTTATTTAATGGTAAAACGTAACGCATTACCATCCTATGT
TGCATTACCGTGGGTTGCGGTAGTCGTACTGATTATCCATCTGCTTTTCTTTGCAACCGATATTACCATTATCAGTGCAA
ATATCTCATCGGCTATTATGTCGGTATTTACTCCGATTACCGTTATCTTCGGTGCGATTTTATTCAACCGCTTCTCCGAA
GCGTCAGGCGTAACCAATACATTACGCAAATGGTTAGGTACGATTAACCCGAATCCGGTGGCGCAACTTATGATCATCGG
TTGGGCGTTCGCATTTATGATTGAAGGTGCGAGCGGTTTCGGTACGCCGGCGGCAATTGCCGCACCGATTTTAGTCGGTT
TAGGCTTTAACCCGATTAAAGTGGCGATCCTTGCATTAATTATGAACTCAGTGCCGGTATCATTCGGTGCGGTAGGTACG
CCGACTTGGTTCGGTTTCGGTTCGCTAAACTTAGCGGAAGCGCAAATTCTTGAAATCGGTTCAATGACCGCATTAATTCA
TGCTTTTGCCGCATTAGTGATTCCAGTAATTGCTCTAAGCTTTATCGTCACTTGGAAAGAAATCCGTCAAAATATCGTAT
TCGTTTATTTAAGCGTATTTGCTTGCGTTATTCCTTATTTCTTCCTTGCACAAGTAAACTACGAATTCCCGTCGTTAGTC
GGCGGCGCAATCGGTATGTTTATTTCGATTTTCCTTGCAAATAAAGGTGTAGGTTTAGCGAAAGTTGAAAATACATTAGA
TAACTCGTCAGTAACGGCAAAAGAAGTCGCAAAAGCATTACTTCCTACCGGCTTACTAATCGGCTTCTTAATCGTAACGC
GTATCCAACAGTTACCGTTTAAAGCGATGATGAACAACACGACCGCTTGGATCAGCACTCAATTAGGTTCATTAGGTCAA
TTTGAAATCAGCCAAGGTTTAGTATTCAGTTTAAAAAATATCTTCGGTACGACGGTAAGTGCAAACTATAAATTACTTTA
TGTGCCGGCATTAATCCCGTTTGTAATTACCGTATTAATTTGTATCCCGTTATTTGCGTTAAGCGGTTCAAAAGTAAAAG
ACGTATTTGCAGGTAGCTTTAAACAAACCAAAAACCCATTTATCGCATTAGTCGGTGCGTTAATCATGGTGAATTTAATG
TTAGTCGGTAACGACGGTTCAATGGTGAAAATCATTGGTAAGAGCTTTGCAGCGGCAACCGGCGAATATTGGACAATCTT
CGCTTCATACTTAGGTGCGGTAGGTGCGTTCTTCTCCGGTTCTAACACGGTATCTAACTTAACTTTCGGTAGCGTACAGT
TATCAACCGCAGAAATTACCGGCTTATCCACTTCATTAGTGCTTGCATTACAATCCGTAGGCGGCGCAATGGGTAACATG
GTATGTATTAACAATATCGTAGCGGTAAACTCAGTATTAAATATTCAAAATCAAGAAGGCGCAATCCTTAAGAAAACTGT
CTTACCGATGTTTATCTACGGCGTGATTGCGGCAATCGTTGCTTTAACGATTATTCCAATCTTCTTTAACGTGTAA

Upstream 100 bases:

>100_bases
CACATCCCCTCTATTTTTTTGAAAAATCTTACATACAATGCAGTTACCTATTTAACATTATTTTAACCATTCATTATTAA
ATTGCATTACGAGGCTTTTT

Downstream 100 bases:

>100_bases
TAACAAAGTGGTAGAGAAAGATTTCTAAAAGACGTGATACACTAACAAGCGGTTAAATTTAAACTTTTTCTACCTATATT
AAGTAAAAGGAAGTCAGCTG

Product: putative L-lactate permease

Products: Proton [Cytoplasm]; lactate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MALFLSIFPIVLLIYLMVKRNALPSYVALPWVAVVVLIIHLLFFATDITIISANISSAIMSVFTPITVIFGAILFNRFSE
ASGVTNTLRKWLGTINPNPVAQLMIIGWAFAFMIEGASGFGTPAAIAAPILVGLGFNPIKVAILALIMNSVPVSFGAVGT
PTWFGFGSLNLAEAQILEIGSMTALIHAFAALVIPVIALSFIVTWKEIRQNIVFVYLSVFACVIPYFFLAQVNYEFPSLV
GGAIGMFISIFLANKGVGLAKVENTLDNSSVTAKEVAKALLPTGLLIGFLIVTRIQQLPFKAMMNNTTAWISTQLGSLGQ
FEISQGLVFSLKNIFGTTVSANYKLLYVPALIPFVITVLICIPLFALSGSKVKDVFAGSFKQTKNPFIALVGALIMVNLM
LVGNDGSMVKIIGKSFAAATGEYWTIFASYLGAVGAFFSGSNTVSNLTFGSVQLSTAEITGLSTSLVLALQSVGGAMGNM
VCINNIVAVNSVLNIQNQEGAILKKTVLPMFIYGVIAAIVALTIIPIFFNV

Sequences:

>Translated_531_residues
MALFLSIFPIVLLIYLMVKRNALPSYVALPWVAVVVLIIHLLFFATDITIISANISSAIMSVFTPITVIFGAILFNRFSE
ASGVTNTLRKWLGTINPNPVAQLMIIGWAFAFMIEGASGFGTPAAIAAPILVGLGFNPIKVAILALIMNSVPVSFGAVGT
PTWFGFGSLNLAEAQILEIGSMTALIHAFAALVIPVIALSFIVTWKEIRQNIVFVYLSVFACVIPYFFLAQVNYEFPSLV
GGAIGMFISIFLANKGVGLAKVENTLDNSSVTAKEVAKALLPTGLLIGFLIVTRIQQLPFKAMMNNTTAWISTQLGSLGQ
FEISQGLVFSLKNIFGTTVSANYKLLYVPALIPFVITVLICIPLFALSGSKVKDVFAGSFKQTKNPFIALVGALIMVNLM
LVGNDGSMVKIIGKSFAAATGEYWTIFASYLGAVGAFFSGSNTVSNLTFGSVQLSTAEITGLSTSLVLALQSVGGAMGNM
VCINNIVAVNSVLNIQNQEGAILKKTVLPMFIYGVIAAIVALTIIPIFFNV
>Mature_530_residues
ALFLSIFPIVLLIYLMVKRNALPSYVALPWVAVVVLIIHLLFFATDITIISANISSAIMSVFTPITVIFGAILFNRFSEA
SGVTNTLRKWLGTINPNPVAQLMIIGWAFAFMIEGASGFGTPAAIAAPILVGLGFNPIKVAILALIMNSVPVSFGAVGTP
TWFGFGSLNLAEAQILEIGSMTALIHAFAALVIPVIALSFIVTWKEIRQNIVFVYLSVFACVIPYFFLAQVNYEFPSLVG
GAIGMFISIFLANKGVGLAKVENTLDNSSVTAKEVAKALLPTGLLIGFLIVTRIQQLPFKAMMNNTTAWISTQLGSLGQF
EISQGLVFSLKNIFGTTVSANYKLLYVPALIPFVITVLICIPLFALSGSKVKDVFAGSFKQTKNPFIALVGALIMVNLML
VGNDGSMVKIIGKSFAAATGEYWTIFASYLGAVGAFFSGSNTVSNLTFGSVQLSTAEITGLSTSLVLALQSVGGAMGNMV
CINNIVAVNSVLNIQNQEGAILKKTVLPMFIYGVIAAIVALTIIPIFFNV

Specific function: May play a role in L-lactate transport [H]

COG id: COG1620

COG function: function code C; L-lactate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lactate permease family [H]

Homologues:

Organism=Escherichia coli, GI1790031, Length=542, Percent_Identity=25.0922509225092, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1789347, Length=149, Percent_Identity=32.2147651006711, Blast_Score=82, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003804 [H]

Pfam domain/function: PF02652 Lactate_perm [H]

EC number: NA

Molecular weight: Translated: 56522; Mature: 56391

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALFLSIFPIVLLIYLMVKRNALPSYVALPWVAVVVLIIHLLFFATDITIISANISSAIM
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHH
SVFTPITVIFGAILFNRFSEASGVTNTLRKWLGTINPNPVAQLMIIGWAFAFMIEGASGF
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCC
GTPAAIAAPILVGLGFNPIKVAILALIMNSVPVSFGAVGTPTWFGFGSLNLAEAQILEIG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCHHHHHHHHHH
SMTALIHAFAALVIPVIALSFIVTWKEIRQNIVFVYLSVFACVIPYFFLAQVNYEFPSLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
GGAIGMFISIFLANKGVGLAKVENTLDNSSVTAKEVAKALLPTGLLIGFLIVTRIQQLPF
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH
KAMMNNTTAWISTQLGSLGQFEISQGLVFSLKNIFGTTVSANYKLLYVPALIPFVITVLI
HHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEECCEEEEEHHHHHHHHHHHHH
CIPLFALSGSKVKDVFAGSFKQTKNPFIALVGALIMVNLMLVGNDGSMVKIIGKSFAAAT
HHHHHHCCCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHEECCCCCEEEEEHHHHHHCC
GEYWTIFASYLGAVGAFFSGSNTVSNLTFGSVQLSTAEITGLSTSLVLALQSVGGAMGNM
CHHHHHHHHHHHHHHHHHCCCCCCCCEEECCEEEEHHHHCCCHHHHHHHHHHHCCHHCCH
VCINNIVAVNSVLNIQNQEGAILKKTVLPMFIYGVIAAIVALTIIPIFFNV
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALFLSIFPIVLLIYLMVKRNALPSYVALPWVAVVVLIIHLLFFATDITIISANISSAIM
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHH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HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; lactate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + lactate [Periplasm] = Proton [Cytoplasm] + lactate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]